A shaker K+ channel with a miniature engineered voltage sensor

Cell

Volumn 142, Issue 4, 2010, Pages 580-589

  Xu, Yanping ^a   Ramu, Yajamana ^a   Lu, Zhe ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cellbio; Molneuro; Proteins

Indexed keywords

ARGININE; COMPLEMENTARY DNA; GLYCINE; SHAKER POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; CHIMERA; CONTROLLED STUDY; GENE DELETION; HYDROPHOBICITY; PERIODICITY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

EID: 77955626630     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2010.07.013     Document Type: Article

References (65)

1. + channel. Neuron 1996, 16:1169-1177.
2. Ahern C.A., Horn R. Specificity of charge-carrying residues in the voltage sensor of potassium channels. J. Gen. Physiol. 2004, 123:205-216.
3. Alabi A.A., Bahamonde M.I., Jung H.J., Kim J.I., Swartz K.J. Portability of paddle motif function and pharmacology in voltage sensors. Nature 2007, 450:370-375.
4. Armstrong C.M. Sodium channels and gating currents. Physiol. Rev. 1981, 61:644-683.
5. Armstrong C.M., Bezanilla F. Currents related to movement of the gating particles of the sodium channels. Nature 1973, 242:459-461.
6. Bosmans F., Martin-Eauclaire M.F., Swartz K.J. Deconstructing voltage sensor function and pharmacology in sodium channels. Nature 2008, 456:202-208.
7. Broomand A., Elinder F. Large-scale movement within the voltage-sensor paddle of a potassium channel-support for a helical-screw motion. Neuron 2008, 59:770-777.
8. Campos F.V., Chanda B., Roux B., Bezanilla F. Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel. Proc. Natl. Acad. Sci. USA 2007, 104:7904-7909.
9. Catterall W.A. Structure and function of voltage-sensitive ion channels. Science 1988, 242:50-61.
10. + channel in a lipid bilayer. Science 2004, 306:491-495.
11. + conduction and selectivity. Science 1998, 280:69-77.
12. Freites J.A., Tobias D.J., von Heijne G., White S.H. Interface connections of a transmembrane voltage sensor. Proc. Natl. Acad. Sci. USA 2005, 102:15059-15064.
13. + channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 1994, 33:6834-6839.
14. Glauner K.S., Mannuzzu L.M., Gandhi C.S., Isacoff E.Y. Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel. Nature 1999, 402:813-817.
15. + channel gating kinetics by deletions in the S3-S4 linker. Proc. Natl. Acad. Sci. USA 2001, 98:9617-9623.
16. Grabe M., Lai H.C., Jain M., Jan Y.N., Jan L.Y. Structure prediction for the down state of a potassium channel voltage sensor. Nature 2007, 445:550-553.
17. + channel. J. Gen. Physiol. 2002, 119:521-532.
18. Hessa T., White S.H., von Heijne G. Membrane insertion of a potassium-channel voltage sensor. Science 2005, 307:1427.
19. Hoshi T., Zagotta W.N., Aldrich R.W. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 1990, 250:533-538.
20. Islas L.D., Sigworth F.J. Voltage sensitivity and gating charge in Shaker and Shab family potassium channels. J. Gen. Physiol. 1999, 114:723-742.
21. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., MacKinnon R. The open pore conformation of potassium channels. Nature 2002, 417:523-526.
22. + channel. Nature 2003, 423:33-41.
23. Khalili-Araghi F., Jogini V., Yarov-Yarovoy V., Tajkhorshid E., Roux B., Schulten K. Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel. Biophys. J. 2010, 98:2189-2198.
24. Kitaguchi T., Sukhareva M., Swartz K.J. Stabilizing the closed S6 gate in the Shaker Kv channel through modification of a hydrophobic seal. J. Gen. Physiol. 2004, 124:319-332.
25. Kubo Y., Baldwin T.J., Jan Y.N., Jan L.Y. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 1993, 362:127-133.
26. + channel S4. Neuron 1996, 16:387-397.
27. +) channel. J. Gen. Physiol. 2000, 115:673-684.
28. + channel. Nature 1991, 353:752-756.
29. + channel determined by construction of multimeric cDNAs. Neuron 1992, 9:861-871.
30. + channel. Neuron 1997, 19:175-184.
31. Long S.B., Campbell E.B., Mackinnon R. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 2005, 309:903-908.
32. Long S.B., Tao X., Campbell E.B., MacKinnon R. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature 2007, 450:376-382.
33. + channels. Neuron 1991, 7:327-336.
34. Lu Z., Klem A.M., Ramu Y. Ion conduction pore is conserved among potassium channels. Nature 2001, 413:809-813.
35. + channels. J. Gen. Physiol. 2002, 120:663-676.
36. Mannuzzu L.M., Moronne M.M., Isacoff E.Y. Direct physical measure of conformational rearrangement underlying potassium channel gating. Science 1996, 271:213-216.
37. Milescu M., Bosmans F., Lee S., Alabi A.A., Kim J.I., Swartz K.J. Interactions between lipids and voltage sensor paddles detected with tarantula toxins. Nat. Struct. Mol. Biol. 2009, 16:1080-1085.
38. Murata Y., Iwasaki H., Sasaki M., Inaba K., Okamura Y. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 2005, 435:1239-1243.
39. Noda M., Shimizu S., Tanabe T., Takai T., Kayano T., Ikeda T., Takahashi H., Nakayama H., Kanaoka Y., Minamino N., et al. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature 1984, 312:121-127.
40. Papazian D.M., Timpe L.C., Jan Y.N., Jan L.Y. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature 1991, 349:305-310.
41. + channel. Neuron 1995, 14:1293-1301.
42. +) channel. Neuron 2007, 56:124-140.
43. + channels. Neuron 1993, 11:353-358.
44. Phillips L.R., Milescu M., Li-Smerin Y., Mindell J.A., Kim J.I., Swartz K.J. Voltage-sensor activation with a tarantula toxin as cargo. Nature 2005, 436:857-860.
45. + channels. Neuron 2008, 59:98-109.
46. Radzicka A., Wolfenden R. Comparing the polarities of the amino acids: side-chain distribution coefficients between the vapor phase, cyclohexane, 1-octanol, and neutral aqueous solution. Biochemistry 1988, 27:1664-1670.
47. Ramsey I.S., Moran M.M., Chong J.A., Clapham D.E. A voltage-gated proton-selective channel lacking the pore domain. Nature 2006, 440:1213-1216.
48. Ramu Y., Xu Y., Lu Z. Enzymatic activation of voltage-gated potassium channels. Nature 2006, 442:696-699.
49. + channel. Cell 2005, 123:463-475.
50. Sasaki M., Takagi M., Okamura Y. A voltage sensor-domain protein is a voltage-gated proton channel. Science 2006, 312:589-592.
51. Schmidt D., Jiang Q.X., MacKinnon R. Phospholipids and the origin of cationic gating charges in voltage sensors. Nature 2006, 444:775-779.
52. Schoppa N.E., McCormack K., Tanouye M.A., Sigworth F.J. The size of gating charge in wild-type and mutant Shaker potassium channels. Science 1992, 255:1712-1715.
53. + channel. Neuron 1996, 16:1159-1167.
54. + channels. Proc. Natl. Acad. Sci. USA 2003, 100:2935-2940.
55. Smith-Maxwell C.J., Ledwell J.L., Aldrich R.W. Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation. J. Gen. Physiol. 1998, 111:421-439.
56. + channel. J. Gen. Physiol. 1998, 112:211-221.
57. + channel. Neuron 1997, 19:1319-1327.
58. Stühmer W., Conti F., Suzuki H., Wang X.D., Noda M., Yahagi N., Kubo H., Numa S. Structural parts involved in activation and inactivation of the sodium channel. Nature 1989, 339:597-603.
59. + channels. Neuron 1997, 18:675-682.
60. + channel. J. Gen. Physiol. 1997, 109:301-311.
61. Tao X., Lee A., Limapichat W., Dougherty D.A., MacKinnon R. A gating charge transfer center in voltage sensors. Science 2010, 328:67-73.
62. + channels. J. Biol. Chem. 2002, 277:18994-19000.
63. + channels. Nature 2008, 451:826-829.
64. Yang N., Horn R. Evidence for voltage-dependent S4 movement in sodium channels. Neuron 1995, 15:213-218.
65. Yang N., George A.L., Horn R. Molecular basis of charge movement in voltage-gated sodium channels. Neuron 1996, 16:113-122.