-
2
-
-
0032479179
-
Anatomy of hot spots in protein interfaces
-
Bogan, A.A., and K.S. Thorn. 1998. Anatomy of hot spots in protein interfaces. J. Mol. Biol. 280:1-9.
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 1-9
-
-
Bogan, A.A.1
Thorn, K.S.2
-
3
-
-
0030840167
-
+ channel with fluorescence
-
+ channel with fluorescence. Neuron. 19:1127-1140.
-
(1997)
Neuron
, vol.19
, pp. 1127-1140
-
-
Cha, A.1
Bezanilla, F.2
-
4
-
-
0032249498
-
Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin
-
Chuang, R.S., H. Jaffe, L. Cribbs, E. Perez-Reyes, and K.J. Swartz. 1998. Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin. Nat. Neurosci. 1:668-674.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 668-674
-
-
Chuang, R.S.1
Jaffe, H.2
Cribbs, L.3
Perez-Reyes, E.4
Swartz, K.J.5
-
5
-
-
0032540358
-
Structural and functional analysis of the 1:1 growth hormone:Receptor complex reveals the molecular basis for receptor affinity
-
Clackson, T., M.H. Ultsch, J.A. Wells, and A.M. de Vos. 1998. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J. Mol. Biol. 277:1111-1128.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 1111-1128
-
-
Clackson, T.1
Ultsch, M.H.2
Wells, J.A.3
De Vos, A.M.4
-
6
-
-
0028916599
-
A hot spot of binding energy in a hormone-receptor interface
-
Clackson, T., and J.A. Wells. 1995. A hot spot of binding energy in a hormone-receptor interface. Science. 267:383-386.
-
(1995)
Science
, vol.267
, pp. 383-386
-
-
Clackson, T.1
Wells, J.A.2
-
7
-
-
0003187567
-
The atomic structure of protein-protein recognition sites
-
Conte, L.L., C. Chothia, and J. Janin. 1999. The atomic structure of protein-protein recognition sites. J. Mol. Biol. 285:2177-2198.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 2177-2198
-
-
Conte, L.L.1
Chothia, C.2
Janin, J.3
-
8
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science. 280:69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Cabral, J.M.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.I.6
Chait, B.T.7
Mackinnon, R.8
-
9
-
-
0030604722
-
Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
-
Doyle, D.A., A. Lee, J. Lewis, E. Kim, M. Sheng, and R. MacKinnon. 1996. Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell. 85:1067-1076.
-
(1996)
Cell
, vol.85
, pp. 1067-1076
-
-
Doyle, D.A.1
Lee, A.2
Lewis, J.3
Kim, E.4
Sheng, M.5
Mackinnon, R.6
-
10
-
-
0024393637
-
A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning
-
Frech, G.C., A.M. VanDongen, G. Schuster, A.M. Brown, and R.H. Joho. 1989. A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature. 340:642-645.
-
(1989)
Nature
, vol.340
, pp. 642-645
-
-
Frech, G.C.1
Vandongen, A.M.2
Schuster, G.3
Brown, A.M.4
Joho, R.H.5
-
13
-
-
0028276482
-
+ channel: Peptide and channel residues mediating molecular recognition
-
+ channel: peptide and channel residues mediating molecular recognition. Neuron. 12:1377-1388.
-
(1994)
Neuron
, vol.12
, pp. 1377-1388
-
-
Goldstein, S.A.1
Pheasant, D.J.2
Miller, C.3
-
15
-
-
0028987938
-
+ channel pore through mutant cycles with a peptide inhibitor
-
+ channel pore through mutant cycles with a peptide inhibitor. Science. 268:307-310.
-
(1995)
Science
, vol.268
, pp. 307-310
-
-
Hidalgo, P.1
MacKinnon, R.2
-
17
-
-
0025996129
-
Identification of amino acid residues involved in dendrotoxin block of rat voltage-dependent potassium channels
-
Hurst, R.S., A.E. Busch, M.P. Kavanaugh, P.B. Osborne, R.A. North, and J.P. Adelman. 1991. Identification of amino acid residues involved in dendrotoxin block of rat voltage-dependent potassium channels. Mol. Pharmacol. 40:572-576.
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 572-576
-
-
Hurst, R.S.1
Busch, A.E.2
Kavanaugh, M.P.3
Osborne, P.B.4
North, R.A.5
Adelman, J.P.6
-
18
-
-
0032552974
-
A snake toxin inhibitor of inward rectifier potassium channel ROMK1
-
Imredy, J.P., C. Chen, and R. MacKinnon. 1998. A snake toxin inhibitor of inward rectifier potassium channel ROMK1. Biochemistry. 37:14867-14874.
-
(1998)
Biochemistry
, vol.37
, pp. 14867-14874
-
-
Imredy, J.P.1
Chen, C.2
Mackinnon, R.3
-
20
-
-
0029113242
-
Solution structure of the potassium channel inhibitor agitoxin 2: Caliper for probing channel geometry
-
Krezel, A.M., C. Kasibhatla, P. Hidalgo, R. MacKinnon, and G. Wagner. 1995. Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Prot. Sci. 4:1478-1489.
-
(1995)
Prot. Sci.
, vol.4
, pp. 1478-1489
-
-
Krezel, A.M.1
Kasibhatla, C.2
Hidalgo, P.3
Mackinnon, R.4
Wagner, G.5
-
21
-
-
0020475449
-
A simple method for displaying the hydropathic character of a protein
-
Kyte, J., and R.F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105-132.
-
(1982)
J. Mol. Biol.
, vol.157
, pp. 105-132
-
-
Kyte, J.1
Doolittle, R.F.2
-
23
-
-
0032894433
-
Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation
-
Ledwell, J.L., and R.W. Aldrich. 1999. Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J. Gen. Physiol. 113:389-414.
-
(1999)
J. Gen. Physiol.
, vol.113
, pp. 389-414
-
-
Ledwell, J.L.1
Aldrich, R.W.2
-
24
-
-
0028369239
-
Images of purified Shaker potassium channels
-
Li, M., N. Unwin, K.A. Stauffer, Y.N. Jan, and L.Y. Jan. 1994. Images of purified Shaker potassium channels. Curr. Biol. 4:110-115.
-
(1994)
Curr. Biol.
, vol.4
, pp. 110-115
-
-
Li, M.1
Unwin, N.2
Stauffer, K.A.3
Jan, Y.N.4
Jan, L.Y.5
-
29
-
-
0030997658
-
+ channel inhibitor from scorpion venom
-
+ channel inhibitor from scorpion venom. Biochemistry. 36:6936-6940.
-
(1997)
Biochemistry
, vol.36
, pp. 6936-6940
-
-
Lu, Z.1
MacKinnon, R.2
-
30
-
-
0032478696
-
Structural conservation in prokaryotic and eukaryotic potassium channels
-
MacKinnon, R., S.L. Cohen, A. Kuo, A. Lee, and B.T. Chait. 1998. Structural conservation in prokaryotic and eukaryotic potassium channels. Science. 280:106-109.
-
(1998)
Science
, vol.280
, pp. 106-109
-
-
MacKinnon, R.1
Cohen, S.L.2
Kuo, A.3
Lee, A.4
Chait, B.T.5
-
32
-
-
0024426645
-
Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor
-
MacKinnon, R., and C. Miller. 1989. Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science. 245:1382-1385.
-
(1989)
Science
, vol.245
, pp. 1382-1385
-
-
MacKinnon, R.1
Miller, C.2
-
33
-
-
0030059224
-
Direct physical measure of conformational rearrangement underlying potassium channel gating
-
Mannuzzu, L.M., M.M. Moronne, and E.Y. Isacoff. 1996. Direct physical measure of conformational rearrangement underlying potassium channel gating. Science. 271:213-216.
-
(1996)
Science
, vol.271
, pp. 213-216
-
-
Mannuzzu, L.M.1
Moronne, M.M.2
Isacoff, E.Y.3
-
34
-
-
0030978579
-
Alteration of P-type calcium channel gating by the spider toxin ω-Aga-IVA
-
McDonough, S.I., I.M. Mintz, and B.P. Bean. 1997. Alteration of P-type calcium channel gating by the spider toxin ω-Aga-IVA. Biophys. J. 72:2117-2128.
-
(1997)
Biophys. J.
, vol.72
, pp. 2117-2128
-
-
McDonough, S.I.1
Mintz, I.M.2
Bean, B.P.3
-
35
-
-
0024147196
-
+ channel by charybdotoxin and tetraethylammonium
-
+ channel by charybdotoxin and tetraethylammonium. Neuron. 1:1003-1006.
-
(1988)
Neuron
, vol.1
, pp. 1003-1006
-
-
Miller, C.1
-
36
-
-
0028983387
-
+ channel-blocking peptides
-
+ channel-blocking peptides. Neuron. 15:5-10.
-
(1995)
Neuron
, vol.15
, pp. 5-10
-
-
Miller, C.1
-
40
-
-
0026032209
-
Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence
-
Papazian, D.M., L.C. Timpe, Y.N. Jan, and L.Y. Jan. 1991. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature. 349:305-310.
-
(1991)
Nature
, vol.349
, pp. 305-310
-
-
Papazian, D.M.1
Timpe, L.C.2
Jan, Y.N.3
Jan, L.Y.4
-
42
-
-
0026666693
-
Mapping function to structure in a channel-blocking peptide: Electrostatic mutants of charybdotoxin
-
Park, C.S., and C. Miller. 1992b. Mapping function to structure in a channel-blocking peptide: electrostatic mutants of charybdotoxin. Biochemistry. 31:7749-7755.
-
(1992)
Biochemistry
, vol.31
, pp. 7749-7755
-
-
Park, C.S.1
Miller, C.2
-
45
-
-
0030064382
-
+ channel selectivity filter by mutant cycle-based structure analysis
-
+ channel selectivity filter by mutant cycle-based structure analysis. Neuron. 16:131-139.
-
(1996)
Neuron
, vol.16
, pp. 131-139
-
-
Ranganathan, R.1
Lewis, J.H.2
MacKinnon, R.3
-
48
-
-
0029056922
-
Energetics of protein-protein interactions: Analysis of the barnase-barstar interface by single mutations and double mutant cycles
-
Schreiber, G., and A.R. Fersht. 1995. Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles. J. Mol. Biol. 248:478-486.
-
(1995)
J. Mol. Biol.
, vol.248
, pp. 478-486
-
-
Schreiber, G.1
Fersht, A.R.2
-
49
-
-
0028841033
-
A prokaryotic potassium ion channel with two predicted transmembrane segments from streptomyces lividans
-
Schrempf, H., O. Schmidt, R. Kummerlen, S. Hinnah, D. Muller, M. Betzler, T. Steinkamp, and R. Wagner. 1995. A prokaryotic potassium ion channel with two predicted transmembrane segments from Streptomyces lividans. EMBO (Eur. Mol. Biol. Organ.) J. 14:5170-5178.
-
(1995)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.14
, pp. 5170-5178
-
-
Schrempf, H.1
Schmidt, O.2
Kummerlen, R.3
Hinnah, S.4
Muller, D.5
Betzler, M.6
Steinkamp, T.7
Wagner, R.8
-
51
-
-
0031905513
-
Role of the S4 in cooperativety of voltage-dependent potassium channel activation
-
Smith-Maxwell, C.J., J.L. Ledwell, and R.W. Aldrich. 1998a. Role of the S4 in cooperativety of voltage-dependent potassium channel activation. J. Gen. Physiol. 111:399-420.
-
(1998)
J. Gen. Physiol.
, vol.111
, pp. 399-420
-
-
Smith-Maxwell, C.J.1
Ledwell, J.L.2
Aldrich, R.W.3
-
52
-
-
0031929388
-
Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation
-
Smith-Maxwell, C.J., J.L. Ledwell, and R.W. Aldrich. 1998b. Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation. J. Gen. Physiol. 111:421-439.
-
(1998)
J. Gen. Physiol.
, vol.111
, pp. 421-439
-
-
Smith-Maxwell, C.J.1
Ledwell, J.L.2
Aldrich, R.W.3
-
53
-
-
0028117321
-
+ channel structure from a complete functional map of the molecular surface of charybdotoxin
-
+ channel structure from a complete functional map of the molecular surface of charybdotoxin. Biochemistry. 33:443-450.
-
(1994)
Biochemistry
, vol.33
, pp. 443-450
-
-
Stampe, P.1
Kolmakova-Partensky, L.2
Miller, C.3
-
56
-
-
0028811258
-
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a
-
Swartz, K.J., and R. MacKinnon. 1995. An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula. Neuron. 15:941-949.
-
(1995)
Chilean Tarantula. Neuron
, vol.15
, pp. 941-949
-
-
Swartz, K.J.1
Mackinnon, R.2
-
57
-
-
0030952979
-
+ channel through multiple binding sites
-
+ channel through multiple binding sites. Neuron. 18:665-673.
-
(1997)
Neuron
, vol.18
, pp. 665-673
-
-
Swartz, K.J.1
MacKinnon, R.2
-
61
-
-
0030021584
-
Molecular basis of charge movement in voltage-gated sodium channels
-
Yang, N., A.L. George, Jr., and R. Horn. 1996. Molecular basis of charge movement in voltage-gated sodium channels. Neuron. 16: 113-122.
-
(1996)
Neuron
, vol.16
, pp. 113-122
-
-
Yang, N.1
George A.L., Jr.2
Horn, R.3
-
62
-
-
0029845542
-
Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel
-
Yusaf, S.P., D. Wray, and A. Sivaprasadarao. 1996. Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel. Pflügers Arch. 433:91-97.
-
(1996)
Pflügers Arch.
, vol.433
, pp. 91-97
-
-
Yusaf, S.P.1
Wray, D.2
Sivaprasadarao, A.3
|