Establishment of recombinant cannabinoid receptor assays and characterization of several natural and synthetic ligands

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 382, Issue 2, 2010, Pages 177-191

  Geiger, Sarah ^a   Nickl, Kathrin ^a   Schneider, Erich H ^a   Seifert, Roland ^b   Heilmann, Jörg ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

9 Tetrahydrocannabinol; Anandamide; Cannabinoid receptor; G protein coupled receptors; Steady state GTPase assay

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ANANDAMIDE; CANNABINOID RECEPTOR; CANNABIS; DODECA 2,4 DIENOIC ACID ISOBUTYLAMIDE; ECHINACEA PURPUREA EXTRACT; GUANOSINE TRIPHOSPHATASE; RECOMBINANT CANNABINOID RECEPTOR; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL MEMBRANE; CEREBELLUM; CONTROLLED STUDY; DRUG SOLUBILITY; ECHINACEA PURPUREA; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LEPIDOPTERA; METABOLITE; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STEADY STATE;

ANIMALS; BACULOVIRIDAE; BINDING, COMPETITIVE; BIOLOGICAL ASSAY; CELL LINE; CELL MEMBRANE; CEREBELLUM; GENETIC VECTORS; HUMANS; LIGANDS; MALE; PLASMIDS; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; RECOMBINANT FUSION PROTEINS; SPLEEN; SPODOPTERA; TRANSFECTION;

EID: 77955553795     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0534-5     Document Type: Article

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