Locomotor activity and occupancy of brain cannabinoid CB1 receptors by the antagonist/inverse agonist AM281

Synapse

Volumn 38, Issue 4, 2000, Pages 477-482

  Cosenza, Melissa ^a   Gifford, Andrew N ^a   Gatley, S John ^a   Pyatt, Beatrice ^a   Liu, Qian ^b   Makriyannis, Alexros ^b   Volkow, Nora D ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Antagonist; Cannabinoid; Locomotor activity; Pyrazole; Radioiodine

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; IODINE 131; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BRAIN LEVEL; DRUG EFFECT; DRUG RECEPTOR BINDING; IC 50; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR OCCUPANCY; SEDATION;

ANIMALS; BRAIN; DRUG COMBINATIONS; MALE; MICE; MORPHOLINES; MOTOR ACTIVITY; NAPHTHALENES; PYRAZOLES; RECEPTORS, CANNABINOID; RECEPTORS, DRUG;

EID: 0034672835     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2396(20001215)38:4<477::AID-SYN13>3.0.CO;2-Y     Document Type: Article

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