-
1
-
-
0028246688
-
(R)-Methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability
-
Abadji V, Lin S, Taha G, Griffin G, Stevenson LA, Pertwee RG and Makriyannis A (1994) (R)-Methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability. J Med Chem 37:1889-1893.
-
(1994)
J Med Chem
, vol.37
, pp. 1889-1893
-
-
Abadji, V.1
Lin, S.2
Taha, G.3
Griffin, G.4
Stevenson, L.A.5
Pertwee, R.G.6
Makriyannis, A.7
-
2
-
-
0029035597
-
Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs
-
Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK and Martin BR (1995) Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. J Pharmacol Exp Ther 273:1172-1181.
-
(1995)
J Pharmacol Exp Ther
, vol.273
, pp. 1172-1181
-
-
Adams, I.B.1
Ryan, W.2
Singer, M.3
Thomas, B.F.4
Compton, D.R.5
Razdan, R.K.6
Martin, B.R.7
-
3
-
-
0010530489
-
SR144528, a potent selective antagonist of the CB2 receptor
-
International Cannabinoid Research Society, Burlington, VT
-
Earth F, Rinaldi-Carmona M, Millan J, Derocq JM, Bouaboula M, Casselas P, Congy C, Oustric D, Sarran M, Calandra B, Portier M, Shire D, Breliere JC and Fur GL (1997) SR144528, a potent selective antagonist of the CB2 receptor. In 1997 Symposium on the cannabinoids, International Cannabinoid Research Society, Burlington, VT.
-
(1997)
1997 Symposium on the Cannabinoids
-
-
Earth, F.1
Rinaldi-Carmona, M.2
Millan, J.3
Derocq, J.M.4
Bouaboula, M.5
Casselas, P.6
Congy, C.7
Oustric, D.8
Sarran, M.9
Calandra, B.10
Portier, M.11
Shire, D.12
Breliere, J.C.13
Fur, G.L.14
-
4
-
-
0029586743
-
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1
-
Bouaboula M, Poinot-Chazel C, Bourrie B, Canta X, Calandra B, Rinaldi-Carmona M, Fur GL and Casellas P (1995) Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1. Biochem J 312:637-641.
-
(1995)
Biochem J
, vol.312
, pp. 637-641
-
-
Bouaboula, M.1
Poinot-Chazel, C.2
Bourrie, B.3
Canta, X.4
Calandra, B.5
Rinaldi-Carmona, M.6
Fur, G.L.7
Casellas, P.8
-
5
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
6
-
-
0030988864
-
Regional differences in cannabinoid receptor/G protein coupling in rat brain
-
Breivogel CS, Sim LJ and Childers SR (1997) Regional differences in cannabinoid receptor/G protein coupling in rat brain. J Pharmacol Exp Ther 282:1632-1642.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 1632-1642
-
-
Breivogel, C.S.1
Sim, L.J.2
Childers, S.R.3
-
7
-
-
0030720938
-
Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain
-
Burkey TH, Quock RM, Consroe P, Ehlert FJ, Hosohata Y, Roeske WR and Yamamura HI (1997) Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. Eur J Pharmacol 336:295-298.
-
(1997)
Eur J Pharmacol
, vol.336
, pp. 295-298
-
-
Burkey, T.H.1
Quock, R.M.2
Consroe, P.3
Ehlert, F.J.4
Hosohata, Y.5
Roeske, W.R.6
Yamamura, H.I.7
-
8
-
-
0027501457
-
Cannabinoid structure-activity relationships: Correlation of receptor binding and in vivo activities
-
Compton DR, Rice KG, De Costa BR, Razdan RK, Melvin LS, Johnson MR and Martin BR (1993) Cannabinoid structure-activity relationships: Correlation of receptor binding and in vivo activities. J Pharmacol Exp Ther 265: 218-226.
-
(1993)
J Pharmacol Exp Ther
, vol.265
, pp. 218-226
-
-
Compton, D.R.1
Rice, K.G.2
De Costa, B.R.3
Razdan, R.K.4
Melvin, L.S.5
Johnson, M.R.6
Martin, B.R.7
-
10
-
-
0024263922
-
Determination and characterization of a cannabinoid receptor in rat brain
-
Devane WA, Dysarz FA, Johnson MR, Melvin LS and Howlett AC (1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34:605-613.
-
(1988)
Mol Pharmacol
, vol.34
, pp. 605-613
-
-
Devane, W.A.1
Dysarz, F.A.2
Johnson, M.R.3
Melvin, L.S.4
Howlett, A.C.5
-
11
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A and Mechoulam R (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949.
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
12
-
-
0026741825
-
Simultaneous coupling of α2-adrenoceptors to two G proteins with opposing effects
-
Eason MG, Kurose H, Holt BD, Raymond JR and Liggett SB (1992) Simultaneous coupling of α2-adrenoceptors to two G proteins with opposing effects. J Biol Chem 267:15795-15801.
-
(1992)
J Biol Chem
, vol.267
, pp. 15795-15801
-
-
Eason, M.G.1
Kurose, H.2
Holt, B.D.3
Raymond, J.R.4
Liggett, S.B.5
-
14
-
-
0031047273
-
Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
-
Glass M, Dragunow M and Faull RLM (1997) Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience 77:299-318.
-
(1997)
Neuroscience
, vol.77
, pp. 299-318
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.M.3
-
15
-
-
0025954862
-
Characterization and localization of cannabinoid receptors in rat brain: A quantative in vitro autographic study
-
Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR and Rice KC (1991) Characterization and localization of cannabinoid receptors in rat brain: A quantative in vitro autographic study. J Neurosci 11:563-583.
-
(1991)
J Neurosci
, vol.11
, pp. 563-583
-
-
Herkenham, M.1
Lynn, A.B.2
Johnson, M.R.3
Melvin, L.S.4
De Costa, B.R.5
Rice, K.C.6
-
16
-
-
0023092620
-
The GTP-binding protein, Go, regulates neuronal calcium channels
-
Hescheler J, Rosenthal W, Trautwein W and Schultz G (1987) The GTP-binding protein, Go, regulates neuronal calcium channels. Nature 325:445-447.
-
(1987)
Nature
, vol.325
, pp. 445-447
-
-
Hescheler, J.1
Rosenthal, W.2
Trautwein, W.3
Schultz, G.4
-
18
-
-
0021722983
-
Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes
-
Hewlett AC and Fleming RM (1984) Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes. Mol Pharmacol 26:532-538.
-
(1984)
Mol Pharmacol
, vol.26
, pp. 532-538
-
-
Hewlett, A.C.1
Fleming, R.M.2
-
19
-
-
0028987880
-
Pharmacology of cannabinoid receptors
-
Howlett AC (1995) Pharmacology of cannabinoid receptors. Annu Rev Pharmacol Toxicol 35:607-634.
-
(1995)
Annu Rev Pharmacol Toxicol
, vol.35
, pp. 607-634
-
-
Howlett, A.C.1
-
20
-
-
0002660089
-
Cannabinoid compounds and signal transduction mechanisms
-
ed. by Roger Pertwee, Academic Press, London
-
Howlett AC (1995) Cannabinoid compounds and signal transduction mechanisms. In Cannabinoid Receptors, ed. by Roger Pertwee, pp 167-204, Academic Press, London.
-
(1995)
Cannabinoid Receptors
, pp. 167-204
-
-
Howlett, A.C.1
-
21
-
-
0029846519
-
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with a high affinity for the CB2 receptor
-
Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH (1996) Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with a high affinity for the CB2 receptor. J Med Chem 39:3875-3877.
-
(1996)
J Med Chem
, vol.39
, pp. 3875-3877
-
-
Huffman, J.W.1
Yu, S.2
Showalter, V.3
Abood, M.E.4
Wiley, J.L.5
Compton, D.R.6
Martin, B.R.7
Bramblett, R.D.8
Reggio, P.H.9
-
22
-
-
0029786614
-
Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves
-
Ishac EJN, Jiang L, Lake KD, Varga K, Abood ME and Kunos G (1996) Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. Br J Pharm 118:2023-2028.
-
(1996)
Br J Pharm
, vol.118
, pp. 2023-2028
-
-
Ishac, E.J.N.1
Jiang, L.2
Lake, K.D.3
Varga, K.4
Abood, M.E.5
Kunos, G.6
-
23
-
-
0026511304
-
Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles
-
Jansen EM, Haycock DA, Ward SJ and Seybold VS (1992) Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles. Brain Res 575:93-102.
-
(1992)
Brain Res
, vol.575
, pp. 93-102
-
-
Jansen, E.M.1
Haycock, D.A.2
Ward, S.J.3
Seybold, V.S.4
-
24
-
-
0029812311
-
The classification of seven transmembrane receptors in recombinant expression systems
-
Kenakin T (1996) The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol Rev 48:451.
-
(1996)
Pharmacol Rev
, vol.48
, pp. 451
-
-
Kenakin, T.1
-
25
-
-
0027379769
-
Aminoalkylindole binding in rat cerebellum: Selective displacement by natural and synthetic cannabinoids
-
Kuster JE, Stevenson JI, Ward SJ, D'Ambra TE and Haycock DA (1993) Aminoalkylindole binding in rat cerebellum: Selective displacement by natural and synthetic cannabinoids. J Pharmacol Exp Ther 264:1352-1363.
-
(1993)
J Pharmacol Exp Ther
, vol.264
, pp. 1352-1363
-
-
Kuster, J.E.1
Stevenson, J.I.2
Ward, S.J.3
D'Ambra, T.E.4
Haycock, D.A.5
-
27
-
-
0027403710
-
μ and d opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma cells
-
Laugwitz K-L, Offermans S, Spicher K and Schultz G (1993) μ and d opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma cells. Neuron 10:233-242.
-
(1993)
Neuron
, vol.10
, pp. 233-242
-
-
Laugwitz, K.-L.1
Offermans, S.2
Spicher, K.3
Schultz, G.4
-
28
-
-
0002866945
-
Structural requirements for cannabinoid receptor probes
-
ed. by R. G. Pertwee, Academic Press, London
-
Martin BR, Thomas BF and Razdan RK (1995) Structural requirements for cannabinoid receptor probes. In Cannabinoid receptors ed. by R. G. Pertwee, p. p. 35-86, Academic Press, London.
-
(1995)
Cannabinoid Receptors
, pp. 35-86
-
-
Martin, B.R.1
Thomas, B.F.2
Razdan, R.K.3
-
29
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC and Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
30
-
-
0029585847
-
Structure-activity relationships defining the ACD-tricyclic cannabinoids: Cannabinoid receptor binding and analgesic activity
-
Melvin LS, Milne GM, Wilken GH and Howlett AC (1995) Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity. Drug Des Discov 13(2):155-166.
-
(1995)
Drug Des Discov
, vol.13
, Issue.2
, pp. 155-166
-
-
Melvin, L.S.1
Milne, G.M.2
Wilken, G.H.3
Howlett, A.C.4
-
31
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL and Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 386:61-64.
-
(1993)
Nature
, vol.386
, pp. 61-64
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
32
-
-
0027249634
-
The evidence for the existence of cannabinoid receptors
-
Pertwee R (1993) The evidence for the existence of cannabinoid receptors. Gen Pharmacol 24:811-824.
-
(1993)
Gen Pharmacol
, vol.24
, pp. 811-824
-
-
Pertwee, R.1
-
33
-
-
0029081885
-
Pharmacological characterisation of three novel cannabinoid receptor agonists in the mouse isolated vas deferens
-
Pertwee RG, Griffin G, Lainton JAH and Huffman JW (1995a) Pharmacological characterisation of three novel cannabinoid receptor agonists in the mouse isolated vas deferens. Eu J Pharm 284:241-247.
-
(1995)
Eu J Pharm
, vol.284
, pp. 241-247
-
-
Pertwee, R.G.1
Griffin, G.2
Lainton, J.A.H.3
Huffman, J.W.4
-
34
-
-
0028924860
-
Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations
-
Pertwee RG, Fernando SR, Griffin G, Abadji V and Makriyannis A (1995b) Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. Eu J Pharm 272:73-78.
-
(1995)
Eu J Pharm
, vol.272
, pp. 73-78
-
-
Pertwee, R.G.1
Fernando, S.R.2
Griffin, G.3
Abadji, V.4
Makriyannis, A.5
-
35
-
-
0028950113
-
A preliminary investigation of the mechanisms underlying cannabinoid tolerance in the mouse vas deferens
-
Pertwee RG and Griffin G (1995) A preliminary investigation of the mechanisms underlying cannabinoid tolerance in the mouse vas deferens. Eu J Pharm 272:67-72.
-
(1995)
Eu J Pharm
, vol.272
, pp. 67-72
-
-
Pertwee, R.G.1
Griffin, G.2
-
36
-
-
0028179209
-
Interaction of δ-opioid receptors with multiple G proteins: A non-relationship between agonist potency to inhibit adeylyl cyclase and to activate G proteins
-
Prather PL, Loh HH and Law PY (1994) Interaction of δ-opioid receptors with multiple G proteins: A non-relationship between agonist potency to inhibit adeylyl cyclase and to activate G proteins. Mol Pharmacol 45:997-1003.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 997-1003
-
-
Prather, P.L.1
Loh, H.H.2
Law, P.Y.3
-
37
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
Rinaldi-Carmona M, Earth F, Heaulme M, Shire D, Calandra B, Congy C, Martinez S, Maruani, J, Neliat G, Caput D, Ferrar P, Soubrie P, Breliere JC and Fur GL (1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 350:240-244.
-
(1994)
FEBS Lett
, vol.350
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
Earth, F.2
Heaulme, M.3
Shire, D.4
Calandra, B.5
Congy, C.6
Martinez, S.7
Maruani, J.8
Neliat, G.9
Caput, D.10
Ferrar, P.11
Soubrie, P.12
Breliere, J.C.13
Fur, G.L.14
-
38
-
-
0013488799
-
3H]SR141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain
-
3H]SR141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain. Life Sci 56:2033-2040, 1996.
-
(1996)
Life Sci
, vol.56
, pp. 2033-2040
-
-
Rinaldi-Carmona, M.1
Pialot, F.2
Congy, C.3
Redon, E.4
Earth, F.5
Bachy, A.6
Breliere, J.-C.7
Soubrie, P.8
Le Fur, G.9
-
40
-
-
0030425575
-
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
-
Showalter VM, Compton DR, Martin BR and Abood ME (1996) Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 278:989-999.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 989-999
-
-
Showalter, V.M.1
Compton, D.R.2
Martin, B.R.3
Abood, M.E.4
-
42
-
-
0029870716
-
The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons
-
Skaper SD, Buriani A, Toso RD, Petrelli L, Romanello S, Facci L and Leon A (1996) The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. Proc Natl Acad Sci USA 93:3984-3989.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3984-3989
-
-
Skaper, S.D.1
Buriani, A.2
Toso, R.D.3
Petrelli, L.4
Romanello, S.5
Facci, L.6
Leon, A.7
-
43
-
-
0028314995
-
Measurement of receptor-stimulated guanosine-5′-O-(γ-thio)triphosphate binding by G proteins
-
Weiland T and Jakobs KH (1994) Measurement of receptor-stimulated guanosine-5′-O-(γ-thio)triphosphate binding by G proteins. Methods Enzymol 237:3-13.
-
(1994)
Methods Enzymol
, vol.237
, pp. 3-13
-
-
Weiland, T.1
Jakobs, K.H.2
|