Evidence for PI3K-dependent CXCR3 agonist-induced degranulation of human cord blood-derived mast cells

Molecular Immunology

Volumn 47, Issue 14, 2010, Pages 2367-2377

  Willox, Ian ^a   Mirkina, Irina ^b   Westwick, John ^b   Ward, Stephen G ^a  

^a University of Bath   (United Kingdom)

^b Novartis Institute for BioMedical Research   (United Kingdom)

Author keywords

Chemokines; Human; Inflammation; Mast cells; Signal transduction

Indexed keywords

ANTIBODY; CD133 ANTIGEN; CHEMOKINE RECEPTOR AGONIST; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR3 B; CXCL11 CHEMOKINE; CXCL4 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; CELL MATURATION; CONTROLLED STUDY; DEGRANULATION; DOWN REGULATION; HUMAN; HUMAN CELL; IC 50; MAST CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UMBILICAL CORD BLOOD;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD; BASE SEQUENCE; CELL DEGRANULATION; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMOKINE CXCL10; CHEMOKINE CXCL11; CHEMOKINE CXCL9; DNA PRIMERS; FETAL BLOOD; GLYCOPROTEINS; HUMANS; INFANT, NEWBORN; MAP KINASE SIGNALING SYSTEM; MAST CELLS; MICROSCOPY, ELECTRON, TRANSMISSION; PEPTIDES; PLATELET FACTOR 4; RECEPTORS, CXCR3; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 77955430014     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.05.005     Document Type: Article

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