A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a G(q/11) protein, phosphatidylinositol 3-kinase β, and protein kinase Cε

Journal of Biological Chemistry

Volumn 273, Issue 48, 1999, Pages 32016-32022

  Graneß, Angela ^a   Adomeit, Antje ^a   Heinze, Regina ^a   Wetzker, Reinhard ^a   Liebmann, Claus ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; BISINDOLYLMALEIMIDE; BRADYKININ; DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGENIC AGENT; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHOSPHOINOSITIDE; PROTEIN KINASE C; RECEPTOR; WORTMANNIN;

ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BRADYKININ; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CHROMONES; COLONIC NEOPLASMS; DIMERIZATION; DNA, NEOPLASM; ENZYME ACTIVATION; ENZYME INHIBITORS; GTP-BINDING PROTEINS; HUMANS; INDOLES; INOSITOL PHOSPHATES; ISOENZYMES; KINETICS; MACROMOLECULAR SUBSTANCES; MALEIMIDES; MODELS, BIOLOGICAL; MORPHOLINES; PERTUSSIS TOXIN; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; RECEPTORS, BRADYKININ; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA;

EID: 0033610835     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.48.32016     Document Type: Article

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