Compromise in mRNA processing machinery in senescent human fibroblasts: Implications for a novel potential role of Phospho-ATR (ser428)

Biogerontology

Volumn 11, Issue 4, 2010, Pages 421-436

  Chandris, Panagiotis ^a,b   Giannouli, Christina C ^a   Panayotou, George ^a   Kletsas, Dimitris ^b  

^a Institute of Molecular Oncology   (Greece)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

Ataxia telangiectasia; ATR; RNA; Senescence; Splicing speckles

Indexed keywords

ATR PROTEIN; MESSENGER RNA; POLYADENYLATED RNA; REACTIVE OXYGEN METABOLITE; SERINE; ATM PROTEIN; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; LAMIN A; LMNA PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL AGING; CELL CYCLE S PHASE; CONFOCAL MICROSCOPY; DNA REPLICATION; ENZYME PHOSPHORYLATION; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IN VITRO STUDY; MESSENGER RNA SYNTHESIS; POLYADENYLATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL NUCLEUS; CYTOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA SPLICING; ULTRASTRUCTURE;

ANIMALS; CELL AGING; CELL CYCLE PROTEINS; CELL LINE; CELL NUCLEUS; DNA REPLICATION; FIBROBLASTS; HUMANS; LAMIN TYPE A; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA SPLICING; RNA, MESSENGER; SERINE; ATAXIA TELANGIECTASIA MUTATED PROTEINS;

EID: 77954951751     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-010-9261-z     Document Type: Article

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