PUF60: A novel U2AF65-related splicing activity

RNA

Volumn 5, Issue 12, 1999, Pages 1548-1560

  Page McCaw, Patrick Schonleber ^a,b   Amonlirdviman, Kevin ^a,c   Sharp, Phillip A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

p54; PUF60; Pump domain; Pyrimidine tract; RRM; Splicing factor; U2AF

Indexed keywords

PROTEIN DERIVATIVE; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENETIC CONSERVATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; RNA SPLICING; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; CELL NUCLEUS; CHROMATOGRAPHY, AFFINITY; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; NUCLEAR PROTEINS; NUCLEOSIDE-DIPHOSPHATE KINASE; POLY U; RIBONUCLEOPROTEINS; RNA SPLICING; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

EID: 0032806445     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838299991938     Document Type: Article

References (48)

1. Abovich N, Liao XC, Rosbash M. 1994. The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes & Dev 8:843-854.
2. Alam MR, Caldwell BD, Johnson RC, Darlington DN, Mains RE, Eipper BA. 1996. Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme. J Biol Chem 271:28636-28640.
3. Barabino SML, Blencowe BJ, Ryder U, Sproat BS, Lamond AI. 1990. Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly. Cell 63:293-302.
4. Berglund JA, Abovich N, Rosbash M. 1998. A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes & Dev 12:858-867.
5. Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. 1997. The splicing factor BBP interacts specifically with the pre-mRNA branch-point sequence UACUAAC. Cell 89:781-787.
6. Birney E, Kumar S, Krainer AR. 1993. Analysis of the RNA-recognition motif and RS and RGG domains: Conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res 21:5803-5816.
7. Chaudhary N, McMahon C, Blobel G. 1991. Primary structure of a human arginine-rich nuclear protein that colocalizes with spliceosome components. Proc Natl Acad Sci USA 88:8189-8193.
8. Chiara MD, Champion-Arnaud P, Buvoli M, Nadal-Ginard B, Reed R. 1994. Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114. Proc Natl Acad Sci USA 91:6403-6407.
9. Creighton TE. 1984. Proteins: Structures and molecular principles. New York: WH Freeman and Company.
10. Crispino JD, Mermoud JE, Lamond Al, Sharp PA. 1996. Cis-acting elements distinct from the 5′ splice site promote U1-independent pre-mRNA splicing. RNA 2:664-673.
11. Dickson BJ. 1998. Photoreceptor development: Breaking down the barriers. Curr Biol 8:R90-R92.
12. Dignam JD, Lebovitz RM, Roeder RD. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
13. Goldenberg DP, Berget PB, King J. 1982. Maturation of the tail spike endorhamnosidase of Salmonella phage P22. J Biol Chem 257: 7864-7871.
14. Gozani O, Feld R, Reed R. 1996. Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes & Dev 10:233-243.
15. Grabowski PJ, Padgett RA, Sharp PA. 1984. Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate. Cell 37:415-427.
16. Harlow E, Lane D. 1988. Antibodies: A laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
17. Hillier LD, Lennon G, Becker M, Bonaldo MF, Chiapelli B, Chissoe S, Dietrich N, DuBuque T, Favello A, Gish W, Hawkins M, Hultman M, Kucaba T, Lacy M, Le M, Le N, Mardis E, Moore B, Morris M, Parsons J, Prange C, Rifkin L, RohlfingT, Schellenberg K, Soares M, Tan F, Thierry-Meg J, Trevaskis E, Underwood K, Wohldman P, Waterston R, Wilson W, Marra M. 1996. Generation and analysis of 280,000 human expressed sequence tags. Genome Res 6:807-828.
18. Imai H, Chan EK, Kiyosawa K, Fu XD, Tan EM. 1993. Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma. J Clin Invest 92:2419-2426.
19. Kanaar R, Roche SE, Beall EL, Green MR, Rio DC. 1993. The conserved pre-mRNA splicing factor U2AF from Drosophila: Requirement for viability. Science 262:569-573.
20. Kennedy CF, Kramer A, Berget SM. 1998. A role for SRp54 during intron bridging of small introns with pyrimidine tracts upstream of the branch point. Mol Cell Biol 18:5425-5434.
21. Konarska MM, Sharp PA. 1986. Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell 46: 845-855.
22. Li S, Li Y, Carthew RW, Lai ZC. 1997. Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional represser Tramtrack. Cell 90:469-478.
23. Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA, Pruisner SB. 1986. Separation and properties of cellular and scrapie prion proteins. Proc Natl Acad Sci USA 83:2310-2314.
24. Michaud S, Reed R. 1991. An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway. Genes & Dev 5:2534-2546.
25. Moore MJ, Sharp PA. 1992. Site-specific modification of pre-mRNA: The 2′ hydroxyl groups at the splice sites. Science 256:992-997.
26. Pan KM, Baldwin M, Nguyen J, Gasset M, Serban A, Groth D, Mehlorn I, Huang Z, Fletterick RJ, Cohen FE, Pruisner SB. 1993. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci USA 90:10962-10966.
27. Peek R, Pruijn GJ, van der Kemp AJ, van Venrooij WJ. 1993. Subcellular distribution of Ro ribonucleoprotein complexes and their constituents. J Cell Sci 106:929-935.
28. Potashkin J, Naik K, Wentz HK. 1993. U2AF homolog required for splicing in vivo. Science 262:573-575.
29. Query CC, McCaw PS, Sharp PA. 1997. A minimal spliceosomal complex A recognizes the branch site and polypyrimidine tract. Mol Cell Biol 17:2944-2953.
30. Query CC, Strobel SA, Sharp PA. 1996. Three recognition events at the branch-site adenine. EMBO J 15:1392-1402.
31. Rain JC, Rafi Z, Rhani Z, Legrain P, Kramer A. 1998. Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1. RNA 4:551-565.
32. Roscigno RF, Weiner M, Garcia-Blanco MA. 1993. A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing. J Biol Chem 268: 11222-11229.
33. Rudner DZ, Kanaar R, Breger KS, Rio DC. 1996. Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. Proc Natl Acad Sci USA 93: 10333-10337.
34. Ruskin B, Zamore PD, Green MR. 1988. A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell 52: 207-219.
35. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: A laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
36. Staknis D, Reed R. 1994. SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol Cell Biol 14:7570-7682.
37. Steinbacher S, Seckler R, Miller S, Steipe B, Huber R, Reinemer P. 1994. Crystal structure of P22 tailspike protein interdigitated subunits in a thermostable trimer. Science 265:383-386.
38. Tronchere H, Wang J, Fu XD. 1997. A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA. Nature 388:397-400.
39. Wahren M, Mellqvist E, Vene S, Ringertz NR, Pettersson I. 1996. Nuclear colocalization of the Ro 60-kDa autoantigen and a subset of U snRNP domains. Eur J Cell Biol 70:189-197.
40. Wentz HK, Potashkin J. 1996. The small subunit of the splicing factor U2AF is conserved in fission yeast. Nucleic Acids Res 24:1849-1854.
41. Zamore PD, Green MR. 1989. Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci USA 86:9243-9247.
42. Zamore PD, Green MR. 1991. Biochemical characterization of U2 snRNP auxiliary factor: An essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J 10:207-214.
43. Zamore PD, Patton JG, Green MR. 1992. Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355: 609-614.
44. Zhang M, Zamore PD, Carmo-Fonseca M, Lamond AI, Green MR. 1992. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc Natl Acad Sci USA 89:8769-8773.
45. Zhang WJ, Wu JY. 1996. Functional properties of p54, a novel SR protein active in constitutive and alternative splicing. Mol Cell Biol 16:5400-5408.
46. Zorio DA, Blumenthal T. 1999. U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans. RNA 4:487-494.
47. Zorio DA, Lea K, Blumenthal T. 1997. Cloning of Caenorhabditis U2AF65: An alternatively spliced RNA containing a novel exon. Mol Cell Biol 17:946-953.
48. Zuo P, Maniatis T. 1996. The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing. Genes & Dev 10:1356-1368.