ATR enforces the topoisomerase II-dependent G 2 checkpoint through inhibition of Plk1 kinase

Journal of Biological Chemistry

Volumn 277, Issue 39, 2002, Pages 36832-36838

  Deming, Paula B ^a,b   Flores, Kristina G ^a,b   Stephen Downes, C ^a,b   Paules, Richard S ^a,b   Kaufmann, William K ^a,b,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOSIS;

CELLS; CHEMICAL REACTIONS; DNA; GENES;

BIOCHEMISTRY;

2,3 BIS(3,5 DIOXO 1 PIPERAZINYL)BUTANE; ATR PROTEIN; CAFFEINE; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DNA TOPOISOMERASE (ATP HYDROLYSING); POLO LIKE KINASE; POLO LIKE KINASE 1; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; ATAXIA TELANGIECTASIA; CELL CYCLE G2 PHASE; CHROMOSOME ABERRATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME MECHANISM; FIBROBLAST; GENETIC STABILITY; HELA CELL; HUMAN; HUMAN CELL; INCIDENCE; INHIBITION KINETICS; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; WILD TYPE;

ALLELES; BLOTTING, WESTERN; CAFFEINE; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL NUCLEUS; CENTRAL NERVOUS SYSTEM STIMULANTS; CHROMOSOME ABERRATIONS; CYCLIN B; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; ENZYME ACTIVATION; FIBROBLASTS; G2 PHASE; HELA CELLS; HUMANS; MITOSIS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TIME FACTORS; TRANSFECTION;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0037184108     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206109200     Document Type: Article

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