Ligand regulation of the quaternary organization of cell surface M 3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogeneous time-resolved FRET

Journal of Biological Chemistry

Volumn 285, Issue 30, 2010, Pages 23318-23330

  Alvarez Curto, Elisa ^a   Ward, Richard J ^a   Pediani, John D ^a   Milligan, Graeme ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

293 CELLS; ACCEPTOR LEVELS; CARBACHOL; CELL SURFACES; CLOZAPINE; CONCENTRATION-DEPENDENT; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIGAND BINDING; MUSCARINIC ACETYLCHOLINE RECEPTORS; ON-DEMAND; PHYSICAL INTERACTIONS; PLASMA MEMBRANES; RATIOMETRIC; RATIOMETRIC FLUORESCENCE; SYNTHETIC LIGANDS; TIME-RESOLVED; WILD TYPES;

CELL MEMBRANES; CLOUDS; COMPLEXATION; ENERGY TRANSFER; FLUORESCENCE; RESONANCE;

LIGANDS;

ACETYLCHOLINE; ATROPINE; CALCIUM ION; CARBACHOL; CLOZAPINE N OXIDE; MUSCARINIC M3 RECEPTOR; RADIOLIGAND; RECEPTOR ACTIVATED SOLELY BY SYNTHETIC LIGAND; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CELL LINE; CELL LYSATE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; FLUORESCENCE IMAGING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; WILD TYPE;

CELL LINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; MOLECULAR IMAGING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RECEPTOR, MUSCARINIC M3; TIME FACTORS;

EID: 77954917965     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.122184     Document Type: Article

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