Fluorescence resonance energy transfer analysis of α 2a- adrenergic receptor activation reveals distinct agonist-specific conformational changes

Molecular Pharmacology

Volumn 75, Issue 3, 2009, Pages 534-541

  Zurn A ^a   Zabel, U ^a   Vilardaga, J P ^b   Schindelin, H ^c   Lohse, M J ^a   Hoffmann, C ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; CLONIDINE; CYAN FLUORESCENT PROTEIN; DOPAMINE; G PROTEIN COUPLED RECEPTOR; NORADRENALIN; OCTOPAMINE; ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2 ADRENERGIC RECEPTOR; LIGAND; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; ANIMAL; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; PROTEIN BINDING;

ADRENERGIC AGONISTS; ANIMALS; CELL LINE; CLONIDINE; DOPAMINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; MICE; NOREPINEPHRINE; OCTOPAMINE; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, ALPHA-2;

EID: 62149089942     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.052399     Document Type: Article

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