Minireview: GPCR and G proteins: Drug efficacy and activation in live cells

Molecular Endocrinology

Volumn 23, Issue 5, 2009, Pages 590-599

  Vilardaga, Jean Pierre ^a,b   Bünemann, Moritz ^c   Feinstein, Timothy N ^a   Lambert, Nevin ^e   Nikolaev, Viacheslav O ^c   Engelhardt, Stefan ^e   Lohse, Martin J ^c,d   Hoffmann, Carsten ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; BUCINDOLOL; CARVEDILOL; CLONIDINE; DOPAMINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; METOPROLOL; MOXONIDINE; NORADRENALIN; OXYMETAZOLINE; RAUWOLSCINE; SEROTONIN 4 AGONIST; YOHIMBINE;

AMINO ACID SUBSTITUTION; BINDING AFFINITY; CELL ACTIVATION; DISSOCIATION; DNA POLYMORPHISM; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG SELECTIVITY; ENERGY TRANSFER; GENE ACTIVATION; GENETIC POLYMORPHISM; HEART FAILURE; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; SHORT SURVEY; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; LUMINESCENCE; METABOLISM; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP-BINDING PROTEINS; HUMANS; KINETICS; LUMINESCENT MEASUREMENTS; MODELS, BIOLOGICAL; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 66649110614     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2008-0204     Document Type: Short Survey

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