Exendin-4 induction of cyclin D1 expression in INS-1 β-cells: Involvement of cAMP-responsive element

Journal of Endocrinology

Volumn 188, Issue 3, 2006, Pages 623-633

  Kim, M J ^a   Kang, J H ^a   Park, Y G ^b   Ryu, G R ^a   Ko, S H ^a   Jeong, I K ^c   Koh, K H ^a   Rhie, D J ^a   Yoon, S H ^a   Hahn, S J ^a   Kim, M S ^a   Jo, Y H ^a  

^a The Catholic University of Korea   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Hallym University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D1; EXENDIN 4; FORSKOLIN; GLUCAGON LIKE PEPTIDE; GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; RAF PROTEIN;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CHROMATIN; CYCLIC AMP RESPONSIVE ELEMENT; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HORMONE ACTION; HORMONE DETERMINATION; IMMUNOPRECIPITATION; NONHUMAN; PANCREAS ISLET CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; FORSKOLIN; GENE EXPRESSION; INSULIN-SECRETING CELLS; ISOQUINOLINES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCAGON; RESPONSE ELEMENTS; RNA, MESSENGER; SULFONAMIDES; VENOMS;

EID: 33645226637     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06480     Document Type: Article

References (37)

1. Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG & Greenberg ME 1998 Fos family members induce cell cycle entry by activating cyclin D1. Molecular and Cellular Biology 18 5609-5619.
2. Brunet A, Roux D, Lenormand P, Dowd S, Keyse S & Pouysségur J 1999 Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO Journal 18 664-674.
3. Bureau J, Foisy S, Rhodes CJ, Carpenter L & Biden TJ 2001 Protein kinase Cζ activation mediates glucagon-like peptide-1-induced pancreatic β-cell proliferation. Diabetes 50 2237-2243.
4. Chang L & Karin M 2001 Mammalian MAP kinase signaling cascades. Nature 410 37-40.
5. 1. Diabetes 53 149-159.
6. D'Amico M, Hulit J, Amanatullah DF, Zafonte BT, Albanese C, Boouzahzah B, Fu M, Augenlicht LH, Donehower LA, Takemaru K et al. 2000 The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3β and cAMP-responsive element binding protein-dependent pathways. Journal of Biological Chemistry 275 32649-32657.
7. De León DD, Deng S, Madani R, Ahima RS & Drucker DJ 2003 Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. Diabetes 52 365-371.
8. Drucker DJ 2003 Glucagon-like peptide-1 and the islet β-cell: augmentation of cell proliferation and inhibition of apoptosis. Endocrinology 144 5145-5148.
9. Drucker DJ, Philippe J, Mojsov S, Chick WL & Habener JF 1987 Glucagon-like peptide-1 stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. PNAS 84 3434-3438.
10. Egan JM, Bulotta A, Hui H & Perfetti R 2003 GLP-1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells. Diabetes/Metabolism Research and Reviews 19 115-123.
11. Frödin M, Sekine N, Roche E, Filloux G, Prentki M, Wollheim C & Van Obberghen E 1995 Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting β-cell line, INS-1. Journal of Biological Chemistry 270 7882-7889.
12. Gallwitz B, Witt M, Folsch UR, Creutzfeldt W & Schmidt WE 1993 Binding specificity and signal transduction of receptors for glucagons-like peptide-1 (7-36) amide and gastric inhibitory polypeptide on RINm5F insulinoma cells. Journal of Molecular Endocrinology 10 259-268.
13. 3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin. Diabetologia 46 222-230.
14. Gerrish K, Cissell MA & Stein R 2001 The role of hepatic nuclear factor 1α and PDX-1 in transcriptional regulation of the pdx-1 gene. Journal of Biological Chemistry 276 47775-47784.
15. Jeon SY, Baek K-H, Kim Y-S, Park C-G, Kwon HS, Ko SH, Song K-H, Yoo SJ, Son HS, Lee KW et al. 2004 Differentially up-regulated genes in proliferating porcine neonatal pancreas cells caused by epidermal growth factor. Journal of Cellular Biochemistry 91 354-364.
16. Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M & Montminy M 2003 cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2. Genes & Development 17 1575-1580.
17. Kim M -J, Ryu GR, Chung J-S, Sim SS, Min DS, Rhie D-J, Yoon SH, Hahn SJ, Kim M-S & Jo Y-H 2003 Protective effects of epicatechin against the toxic effects of streptozotocin on rat pancreatic islets: in vivo and in vitro. Pancreas 26 292-299.
18. Kim M-J, Ryu GR, Kang J-H, Sim SS, Min DS, Rhie D-J, Yoon SH, Hahn SJ, Jeong I-K, Hong K-J et al. 2004 Inhibitory effects of epicatechin on interleukin-1-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-B activation. Biochemical Pharmacology 68 1775-1785.
19. Kushner JA, Ciemerych MA, Sicinska E, Wartschow LM, Teta M, Long SY, Sicinski P & White MF 2005 Cyclins D2 and D1 are essential for postnatal pancreatic β-cell growth. Molecular and Cellular Biology 25 3752-3762.
20. Lalli E & Sassone-Corsi P 1994 Signal transduction and gene regulation. Journal of Biological Chemistry 269 17359-17362.
21. Leech CA, Castonguay MA & Habener JF 1999 Expression of adenylyl cyclase subtypes in pancreatic β-cells. Biochemical and Biophysical Research Communications 254 703-706.
22. List JF & Habener JF 2004 Glucagon-like peptide 1 agonists and the development and growth of pancreatic β-cells. American Journal of Physiology Endocrinology and Metabolism 286 E875-E881.
23. Matsushime H, Ewen ME, Strom DK, Kato JY, Hanks SK, Roussel MF & Sherr CJ 1992 Identification and properties of an atypical catalytic subunit (p34 PSK-J3/Cdk4) for mammalian D type G1 cyclins. Cell 71 323-334.
24. Montminy M 1997 Transcriptional regulation by cyclic AMP. Annual Review of Biochemistry 66 807-822.
25. Moriuchi A, Ido A, Nagata Y, Nagata K, Uto H, Hasuike S, Hori T, Hirono S, Hayashi K & Tsubouchi H 2003 A CRE and the region occupied by a protein induced by growth factors contribute to up-regulation of cyclin D1 expression in hepatocytes. Biochemical and Biophysical Research Communications 300 415-421.
26. Nagata D, Suzuki E, Nishimatsu H, Satonaka H, Goto A, Omata M & Hirata Y 2001 Transcriptional activation of the cyclin D1 gene is mediated by multiple cis-elements, including SP1 sites and a cAMP-responsive element in vascular endothelial cells. Journal of Biological Chemistry 276 662-669.
27. Ørskov C 1992 Glucagon-like peptide-1, a new hormone of the entero-insular axis. Diabetologia 35 701-711.
28. Perfetti R & Merkel P 2000 Glucagon-like peptide-1: a major regulator of pancreatic β-cell function. European Journal of Endocrinology 143 717-725.
29. Perry T & Greig NH 2003 The glucagon-like peptides: a double-edged therapeutic sword? Trends in Pharmacological Sciences 24 377-383.
30. Rosenberg D, Groussin L, Jullian E, Perlemoine K, Bertagna X & Bertherat J 2002 Role of the PKA-regulated transcription factor CREB in development and tumorigenesis of endocrine tissues. Annals of the New York Academy of Sciences 968 65-74.
31. Sabbah M, Courilleau D, Mester J & Redeuilh G 1999 Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element. PNAS 96 11217-11222.
32. Sherr CJ 1994 G1 phase progression: cycling on cue. Cell 79 551-555.
33. Susini S, Roche E, Prentki M & Schlegel W 1998 Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, zif268, and nur-77 gene expression in pancreatic β(INS-1) cells. FASEB Journal 12 1173-1182.
34. Tourrel C, Bailbé D, Meile M-J, Kergoat M & Portha B 2001 Glucagon-like peptide-1 and exendin-4 stimulate β-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age. Diabetes 50 1562-1570.
35. Tourrel C, Bailbé D, Lacorne M, Meile M-J, Kergoat M & Portha B 2002 Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagons-like peptide-1 or exendin-4. Diabetes 51 1443-1552.
36. Xu G, Scoffers DA, Habener JF & Bonner-Weir S 1999 Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 2270-2276.
37. Yan Y-X, Nakagawa H, Lee M-H & Rustgi AK 1997 Transforming growth factor-α enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter. Journal of Biological Chemistry 272 33181-33190.