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Volumn 201, Issue 1, 2008, Pages 101-107

Co-administration of berberine and plant stanols synergistically reduces plasma cholesterol in rats

Author keywords

Berberine; Liver cholesterol; Plant stanols; Plasma cholesterol; Plasma triacylglyceride; Rats; Toxicity

Indexed keywords

BERBERINE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; STANOL ESTER;

EID: 52049116419     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.03.008     Document Type: Article
Times cited : (33)

References (70)
  • 1
    • 0242490816 scopus 로고    scopus 로고
    • Pharmacotherapy for dyslipidaemia-current therapies and future agents
    • Bays H., and Stein E.A. Pharmacotherapy for dyslipidaemia-current therapies and future agents. Exp Opin Pharmacother 4 (2003) 1901-1938
    • (2003) Exp Opin Pharmacother , vol.4 , pp. 1901-1938
    • Bays, H.1    Stein, E.A.2
  • 2
    • 0014976138 scopus 로고
    • Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study
    • Kannel W.B., Castelli W.P., Gordon T., and McNamara P.M. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. Ann Intern Med 74 (1971) 1-12
    • (1971) Ann Intern Med , vol.74 , pp. 1-12
    • Kannel, W.B.1    Castelli, W.P.2    Gordon, T.3    McNamara, P.M.4
  • 3
    • 30744455025 scopus 로고    scopus 로고
    • Recent studies of lipoprotein kinetics in the metabolic syndrome and related disorders
    • Chan D.C., Barrett P.H., and Watts G.F. Recent studies of lipoprotein kinetics in the metabolic syndrome and related disorders. Curr Opin Lipidol 17 (2006) 28-36
    • (2006) Curr Opin Lipidol , vol.17 , pp. 28-36
    • Chan, D.C.1    Barrett, P.H.2    Watts, G.F.3
  • 4
    • 0035818574 scopus 로고    scopus 로고
    • Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice
    • Merkel M., Velez-Carrasco W., Hudgins L.C., and Breslow J.L. Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice. Proc Natl Acad Sci USA 98 (2001) 13294-13299
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13294-13299
    • Merkel, M.1    Velez-Carrasco, W.2    Hudgins, L.C.3    Breslow, J.L.4
  • 5
    • 0022980592 scopus 로고
    • Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361,662 men
    • Martin M.J., Hulley S.B., Browner W.S., Kuller L.H., and Wentworth D. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361,662 men. Lancet 2 (1986) 933-936
    • (1986) Lancet , vol.2 , pp. 933-936
    • Martin, M.J.1    Hulley, S.B.2    Browner, W.S.3    Kuller, L.H.4    Wentworth, D.5
  • 6
    • 0027505992 scopus 로고
    • Serum cholesterol in young men and subsequent cardiovascular disease
    • Klag M.J., Ford D.E., Mead L.A., et al. Serum cholesterol in young men and subsequent cardiovascular disease. N Engl J Med 328 (1993) 313-318
    • (1993) N Engl J Med , vol.328 , pp. 313-318
    • Klag, M.J.1    Ford, D.E.2    Mead, L.A.3
  • 7
    • 33748294814 scopus 로고    scopus 로고
    • Metabolic syndrome, low-density lipoprotein cholesterol, and risk of cardiovascular disease: a population-based study
    • Jeppesen J., Hansen T.W., Rasmussen S., Ibsen H., and Torp-Pedersen C. Metabolic syndrome, low-density lipoprotein cholesterol, and risk of cardiovascular disease: a population-based study. Atherosclerosis 189 (2006) 369-374
    • (2006) Atherosclerosis , vol.189 , pp. 369-374
    • Jeppesen, J.1    Hansen, T.W.2    Rasmussen, S.3    Ibsen, H.4    Torp-Pedersen, C.5
  • 8
    • 0032947470 scopus 로고    scopus 로고
    • Triglyceride as a risk factor for ischaemic heart disease in British men: effect of adjusting for measurement error
    • Egger M., Smith G.D., Pfluger D., Altpeter E., and Elwood P.C. Triglyceride as a risk factor for ischaemic heart disease in British men: effect of adjusting for measurement error. Atherosclerosis 143 (1999) 275-284
    • (1999) Atherosclerosis , vol.143 , pp. 275-284
    • Egger, M.1    Smith, G.D.2    Pfluger, D.3    Altpeter, E.4    Elwood, P.C.5
  • 9
    • 0035825927 scopus 로고    scopus 로고
    • Pro and con: high-density lipoprotein, triglycerides, and other lipid subfractions are the future of lipid management
    • Assmann G. Pro and con: high-density lipoprotein, triglycerides, and other lipid subfractions are the future of lipid management. Am J Cardiol 87 (2001) 2B-7B
    • (2001) Am J Cardiol , vol.87
    • Assmann, G.1
  • 10
    • 34548485062 scopus 로고    scopus 로고
    • The role of hypertriglyceridemia in atherosclerosis
    • Le N.A., and Walter M.F. The role of hypertriglyceridemia in atherosclerosis. Curr Atheroscler Rep 9 (2007) 110-115
    • (2007) Curr Atheroscler Rep , vol.9 , pp. 110-115
    • Le, N.A.1    Walter, M.F.2
  • 11
    • 0032567996 scopus 로고    scopus 로고
    • Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome
    • Grundy S.M. Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome. Am J Cardiol 81 (1998) 18B-25B
    • (1998) Am J Cardiol , vol.81
    • Grundy, S.M.1
  • 12
    • 0036895750 scopus 로고    scopus 로고
    • Unesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons
    • Vanstone C.A., Raeini-Sarjaz M., Parsons W.E., and Jones P.J. Unesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons. Am J Clin Nutr 76 (2002) 1272-1278
    • (2002) Am J Clin Nutr , vol.76 , pp. 1272-1278
    • Vanstone, C.A.1    Raeini-Sarjaz, M.2    Parsons, W.E.3    Jones, P.J.4
  • 13
    • 19944374769 scopus 로고    scopus 로고
    • Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
    • Kong W., Wei J., Abidi P., et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med 10 (2004) 1344-1351
    • (2004) Nat Med , vol.10 , pp. 1344-1351
    • Kong, W.1    Wei, J.2    Abidi, P.3
  • 15
    • 10644293873 scopus 로고    scopus 로고
    • Lipids in health and disease
    • Shepherd J. Lipids in health and disease. Biochem Soc Trans 32 (2004) 1051-1056
    • (2004) Biochem Soc Trans , vol.32 , pp. 1051-1056
    • Shepherd, J.1
  • 16
    • 33144483670 scopus 로고    scopus 로고
    • The role of statins in clinical medicine-LDL-cholesterol lowering and beyond
    • Rutishauser J. The role of statins in clinical medicine-LDL-cholesterol lowering and beyond. Swiss Med Wkly 136 (2006) 41-49
    • (2006) Swiss Med Wkly , vol.136 , pp. 41-49
    • Rutishauser, J.1
  • 17
    • 6344245933 scopus 로고    scopus 로고
    • Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage. Prescrire Int 2004;13:176-9.
    • Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage. Prescrire Int 2004;13:176-9.
  • 18
    • 31144469006 scopus 로고    scopus 로고
    • Mechanisms of rhabdomyolysis with statins
    • Magalhaes M.E. Mechanisms of rhabdomyolysis with statins. Arq Bras Cardiol 85 Suppl. 5 (2005) 42-44
    • (2005) Arq Bras Cardiol , vol.85 , Issue.SUPPL. 5 , pp. 42-44
    • Magalhaes, M.E.1
  • 19
    • 0032697540 scopus 로고    scopus 로고
    • Poor responders to statins: a potential target fro stanol esters
    • Thompson G.R. Poor responders to statins: a potential target fro stanol esters. Eur Heart J Suppl 1 (1999) S114-S117
    • (1999) Eur Heart J Suppl , vol.1
    • Thompson, G.R.1
  • 20
    • 16544395078 scopus 로고    scopus 로고
    • Plant sterols and endurance training combine to favorably alter plasma lipid profiles in previously sedentary hypercholesterolemic adults after 8 wk
    • Varady K.A., Ebine N., Vanstone C.A., Parsons W.E., and Jones P.J. Plant sterols and endurance training combine to favorably alter plasma lipid profiles in previously sedentary hypercholesterolemic adults after 8 wk. Am J Clin Nutr 80 (2004) 1159-1166
    • (2004) Am J Clin Nutr , vol.80 , pp. 1159-1166
    • Varady, K.A.1    Ebine, N.2    Vanstone, C.A.3    Parsons, W.E.4    Jones, P.J.5
  • 21
    • 33744988148 scopus 로고    scopus 로고
    • Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols
    • Korpela R., Tuomilehto J., Hogstrom P., et al. Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols. Eur J Clin Nutr 60 (2006) 633-642
    • (2006) Eur J Clin Nutr , vol.60 , pp. 633-642
    • Korpela, R.1    Tuomilehto, J.2    Hogstrom, P.3
  • 22
    • 34247192604 scopus 로고    scopus 로고
    • The lipid lowering effect of plant sterol ester capsules in hypercholesterolemic subjects
    • Acuff R.V., Cai D.J., Dong Z.P., and Bell D. The lipid lowering effect of plant sterol ester capsules in hypercholesterolemic subjects. Lipids Health Dis 6 (2007) 11
    • (2007) Lipids Health Dis , vol.6 , pp. 11
    • Acuff, R.V.1    Cai, D.J.2    Dong, Z.P.3    Bell, D.4
  • 23
    • 0034122924 scopus 로고    scopus 로고
    • Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters
    • Jones P.J., Raeini-Sarjaz M., Ntanios F.Y., et al. Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters. J Lipid Res 41 (2000) 697-705
    • (2000) J Lipid Res , vol.41 , pp. 697-705
    • Jones, P.J.1    Raeini-Sarjaz, M.2    Ntanios, F.Y.3
  • 24
    • 0034012947 scopus 로고    scopus 로고
    • Serum, biliary, and fecal cholesterol and plant sterols in colectomized patients before and during consumption of stanol ester margarine
    • Miettinen T.A., Vuoristo M., Nissinen M., Jarvinen H.J., and Gylling H. Serum, biliary, and fecal cholesterol and plant sterols in colectomized patients before and during consumption of stanol ester margarine. Am J Clin Nutr 71 (2000) 1095-1102
    • (2000) Am J Clin Nutr , vol.71 , pp. 1095-1102
    • Miettinen, T.A.1    Vuoristo, M.2    Nissinen, M.3    Jarvinen, H.J.4    Gylling, H.5
  • 25
    • 0345493907 scopus 로고    scopus 로고
    • Sitostanol administered in lecithin micelles potently reduces cholesterol absorption in humans
    • Ostlund Jr. R.E., Spilburg C.A., and Stenson W.F. Sitostanol administered in lecithin micelles potently reduces cholesterol absorption in humans. Am J Clin Nutr 70 (1999) 826-831
    • (1999) Am J Clin Nutr , vol.70 , pp. 826-831
    • Ostlund Jr., R.E.1    Spilburg, C.A.2    Stenson, W.F.3
  • 26
    • 33845595888 scopus 로고    scopus 로고
    • The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms
    • Abidi P., Chen W., Kraemer F.B., Li H., and Liu J. The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms. J Lipid Res 47 (2006) 2134-2147
    • (2006) J Lipid Res , vol.47 , pp. 2134-2147
    • Abidi, P.1    Chen, W.2    Kraemer, F.B.3    Li, H.4    Liu, J.5
  • 27
    • 26244452375 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine
    • Abidi P., Zhou Y., Jiang J.D., and Liu J. Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine. Arterioscler Thromb Vasc Biol 25 (2005) 2170-2176
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2170-2176
    • Abidi, P.1    Zhou, Y.2    Jiang, J.D.3    Liu, J.4
  • 28
    • 0032961863 scopus 로고    scopus 로고
    • Spreads enriched with three different levels of vegetable oil sterols and the degree of cholesterol lowering in normocholesterolaemic and mildly hypercholesterolaemic subjects
    • Hendriks H.F., Weststrate J.A., van Vliet T., and Meijer G.W. Spreads enriched with three different levels of vegetable oil sterols and the degree of cholesterol lowering in normocholesterolaemic and mildly hypercholesterolaemic subjects. Eur J Clin Nutr 53 (1999) 319-327
    • (1999) Eur J Clin Nutr , vol.53 , pp. 319-327
    • Hendriks, H.F.1    Weststrate, J.A.2    van Vliet, T.3    Meijer, G.W.4
  • 29
    • 0032966743 scopus 로고    scopus 로고
    • Effects of 2 low-fat stanol ester-containing margarines on serum cholesterol concentrations as part of a low-fat diet in hypercholesterolemic subjects
    • Hallikainen M.A., and Uusitupa M.I. Effects of 2 low-fat stanol ester-containing margarines on serum cholesterol concentrations as part of a low-fat diet in hypercholesterolemic subjects. Am J Clin Nutr 69 (1999) 403-410
    • (1999) Am J Clin Nutr , vol.69 , pp. 403-410
    • Hallikainen, M.A.1    Uusitupa, M.I.2
  • 30
    • 0033049497 scopus 로고    scopus 로고
    • Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men
    • Jones P.J., Ntanios F.Y., Raeini-Sarjaz M., and Vanstone C.A. Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men. Am J Clin Nutr 69 (1999) 1144-1150
    • (1999) Am J Clin Nutr , vol.69 , pp. 1144-1150
    • Jones, P.J.1    Ntanios, F.Y.2    Raeini-Sarjaz, M.3    Vanstone, C.A.4
  • 31
    • 0042206849 scopus 로고    scopus 로고
    • Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
    • Katan M.B., Grundy S.M., Jones P., et al. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc 78 (2003) 965-978
    • (2003) Mayo Clin Proc , vol.78 , pp. 965-978
    • Katan, M.B.1    Grundy, S.M.2    Jones, P.3
  • 32
    • 3042743975 scopus 로고    scopus 로고
    • Combination of phytosterols and omega-3 fatty acids: a potential strategy to promote cardiovascular health
    • Normen L., Shaw C.A., Fink C.S., and Awad A.B. Combination of phytosterols and omega-3 fatty acids: a potential strategy to promote cardiovascular health. Curr Med Chem Cardiovasc Hematol Agents 2 (2004) 1-12
    • (2004) Curr Med Chem Cardiovasc Hematol Agents , vol.2 , pp. 1-12
    • Normen, L.1    Shaw, C.A.2    Fink, C.S.3    Awad, A.B.4
  • 33
    • 0032894986 scopus 로고    scopus 로고
    • Cholesterol reduction by different plant stanol mixtures and with variable fat intake
    • Gylling H., and Miettinen T.A. Cholesterol reduction by different plant stanol mixtures and with variable fat intake. Metabolism 48 (1999) 575-580
    • (1999) Metabolism , vol.48 , pp. 575-580
    • Gylling, H.1    Miettinen, T.A.2
  • 34
    • 0031745196 scopus 로고    scopus 로고
    • Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hypercholesterolaemic subjects
    • Weststrate J.A., and Meijer G.W. Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hypercholesterolaemic subjects. Eur J Clin Nutr 52 (1998) 334-343
    • (1998) Eur J Clin Nutr , vol.52 , pp. 334-343
    • Weststrate, J.A.1    Meijer, G.W.2
  • 35
    • 11344284960 scopus 로고    scopus 로고
    • Plant sterol/stanol prescription is an effective treatment strategy for managing hypercholesterolemia in outpatient clinical practice
    • Patch C.S., Tapsell L.C., and Williams P.G. Plant sterol/stanol prescription is an effective treatment strategy for managing hypercholesterolemia in outpatient clinical practice. J Am Diet Assoc 105 (2005) 46-52
    • (2005) J Am Diet Assoc , vol.105 , pp. 46-52
    • Patch, C.S.1    Tapsell, L.C.2    Williams, P.G.3
  • 36
    • 0028869083 scopus 로고
    • A diet moderately enriched in phytosterols lowers plasma cholesterol concentrations in normocholesterolemic humans
    • Pelletier X., Belbraouet S., Mirabel D., et al. A diet moderately enriched in phytosterols lowers plasma cholesterol concentrations in normocholesterolemic humans. Ann Nutr Metab 39 (1995) 291-295
    • (1995) Ann Nutr Metab , vol.39 , pp. 291-295
    • Pelletier, X.1    Belbraouet, S.2    Mirabel, D.3
  • 37
    • 33748086019 scopus 로고    scopus 로고
    • Endothelial function in hypercholesterolemic subjects: effects of plant stanol and sterol esters
    • Hallikainen M., Lyyra-Laitinen T., Laitinen T., et al. Endothelial function in hypercholesterolemic subjects: effects of plant stanol and sterol esters. Atherosclerosis 188 (2005) 425-432
    • (2005) Atherosclerosis , vol.188 , pp. 425-432
    • Hallikainen, M.1    Lyyra-Laitinen, T.2    Laitinen, T.3
  • 38
    • 0020004724 scopus 로고
    • 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol
    • 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 28 (1982) 1379-1388
    • (1982) Clin Chem , vol.28 , pp. 1379-1388
    • Warnick, G.R.1    Benderson, J.2    Albers, J.J.3
  • 39
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 40
    • 1842817729 scopus 로고    scopus 로고
    • Soy protein reduces triglyceride levels and triglyceride fatty acid fractional synthesis rate in hypercholesterolemic subjects
    • Wang Y., Jones P.J., Ausman L.M., and Lichtenstein A.H. Soy protein reduces triglyceride levels and triglyceride fatty acid fractional synthesis rate in hypercholesterolemic subjects. Atherosclerosis 173 (2004) 269-275
    • (2004) Atherosclerosis , vol.173 , pp. 269-275
    • Wang, Y.1    Jones, P.J.2    Ausman, L.M.3    Lichtenstein, A.H.4
  • 41
    • 0024730409 scopus 로고
    • Evaluation of the antiatherosclerotic properties of natural compounds of plant origin on cell cultures of the human aortic intima
    • Ren L.H., Vasil'ev A.V., Orkehov A.N., Tertov V.V., and Tutel'ian V.A. Evaluation of the antiatherosclerotic properties of natural compounds of plant origin on cell cultures of the human aortic intima. Farmakol Toksikol 52 (1989) 44-46
    • (1989) Farmakol Toksikol , vol.52 , pp. 44-46
    • Ren, L.H.1    Vasil'ev, A.V.2    Orkehov, A.N.3    Tertov, V.V.4    Tutel'ian, V.A.5
  • 42
    • 0026649758 scopus 로고
    • Studies on the antinephritic effect of plant components. (4). Reduction of protein excretion by berberine and coptisine in rats with original-type anti-GBM nephritis
    • Hattori T., Furuta K., Nagao T., et al. Studies on the antinephritic effect of plant components. (4). Reduction of protein excretion by berberine and coptisine in rats with original-type anti-GBM nephritis. Jpn J Pharmacol 59 (1992) 159-169
    • (1992) Jpn J Pharmacol , vol.59 , pp. 159-169
    • Hattori, T.1    Furuta, K.2    Nagao, T.3
  • 43
    • 1842708890 scopus 로고    scopus 로고
    • Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion
    • Leng S.H., Lu F.E., and Xu L.J. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacol Sin 25 (2004) 496-502
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 496-502
    • Leng, S.H.1    Lu, F.E.2    Xu, L.J.3
  • 44
    • 0027243366 scopus 로고
    • Animal models of human lipid metabolism
    • Suckling K.E., and Jackson B. Animal models of human lipid metabolism. Prog Lipid Res 32 (1993) 1-24
    • (1993) Prog Lipid Res , vol.32 , pp. 1-24
    • Suckling, K.E.1    Jackson, B.2
  • 45
    • 0030898403 scopus 로고    scopus 로고
    • Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: human and animal studies
    • Kris-Etherton P.M., and Dietschy J. Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: human and animal studies. Am J Clin Nutr 65 (1997) S1590-S1596
    • (1997) Am J Clin Nutr , vol.65
    • Kris-Etherton, P.M.1    Dietschy, J.2
  • 46
    • 31544483596 scopus 로고    scopus 로고
    • Comparative aspects of lipid metabolism: impact on contemporary research and use of animal models
    • Bergen W.G., and Mersmann H.J. Comparative aspects of lipid metabolism: impact on contemporary research and use of animal models. J Nutr 135 (2005) 2499-2502
    • (2005) J Nutr , vol.135 , pp. 2499-2502
    • Bergen, W.G.1    Mersmann, H.J.2
  • 47
    • 33749327046 scopus 로고    scopus 로고
    • Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats
    • Tang L.Q., Wei W., Chen L.M., and Liu S. Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats. J Ethnopharmacol 108 (2006) 109-115
    • (2006) J Ethnopharmacol , vol.108 , pp. 109-115
    • Tang, L.Q.1    Wei, W.2    Chen, L.M.3    Liu, S.4
  • 48
    • 0036300607 scopus 로고    scopus 로고
    • Free phytosterols effectively reduce plasma and liver cholesterol in gerbils fed cholesterol
    • Hayes K.C., Pronczuk A., Wijendran V., and Beer M. Free phytosterols effectively reduce plasma and liver cholesterol in gerbils fed cholesterol. J Nutr 132 (2002) 1983-1988
    • (2002) J Nutr , vol.132 , pp. 1983-1988
    • Hayes, K.C.1    Pronczuk, A.2    Wijendran, V.3    Beer, M.4
  • 49
    • 31344448041 scopus 로고    scopus 로고
    • Rapeseed oil, olive oil, plant sterols, and cholesterol metabolism: an ileostomy study
    • Ellegard L., Andersson H., and Bosaeus I. Rapeseed oil, olive oil, plant sterols, and cholesterol metabolism: an ileostomy study. Eur J Clin Nutr 59 (2005) 1374-1378
    • (2005) Eur J Clin Nutr , vol.59 , pp. 1374-1378
    • Ellegard, L.1    Andersson, H.2    Bosaeus, I.3
  • 50
    • 22144499587 scopus 로고    scopus 로고
    • Free phytosterols facilitate excretion of endogenous cholesterol in gerbils
    • Hayes K.C., Pronczuk A., Wijendran V., and Beer M. Free phytosterols facilitate excretion of endogenous cholesterol in gerbils. J Nutr Biochem 16 (2005) 305-311
    • (2005) J Nutr Biochem , vol.16 , pp. 305-311
    • Hayes, K.C.1    Pronczuk, A.2    Wijendran, V.3    Beer, M.4
  • 51
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
    • Lee Y.S., Kim W.S., Kim K.H., et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 55 (2006) 2256-2264
    • (2006) Diabetes , vol.55 , pp. 2256-2264
    • Lee, Y.S.1    Kim, W.S.2    Kim, K.H.3
  • 52
    • 33744804815 scopus 로고    scopus 로고
    • Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine
    • Brusq J.M., Ancellin N., Grondin P., et al. Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine. J Lipid Res 47 (2006) 1281-1288
    • (2006) J Lipid Res , vol.47 , pp. 1281-1288
    • Brusq, J.M.1    Ancellin, N.2    Grondin, P.3
  • 53
    • 33846185097 scopus 로고    scopus 로고
    • Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte
    • Choi B.H., Ahn I.S., Kim Y.H., et al. Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte. Exp Mol Med 38 (2006) 599-605
    • (2006) Exp Mol Med , vol.38 , pp. 599-605
    • Choi, B.H.1    Ahn, I.S.2    Kim, Y.H.3
  • 55
    • 0029585418 scopus 로고
    • Enhanced efficacy of sitostanol-containing versus sitostanol-free phytosterol mixtures in altering lipoprotein cholesterol levels and synthesis in rats
    • Ling W.H., and Jones P.J. Enhanced efficacy of sitostanol-containing versus sitostanol-free phytosterol mixtures in altering lipoprotein cholesterol levels and synthesis in rats. Atherosclerosis 118 (1995) 319-331
    • (1995) Atherosclerosis , vol.118 , pp. 319-331
    • Ling, W.H.1    Jones, P.J.2
  • 56
    • 21944443404 scopus 로고    scopus 로고
    • Plant sterols are efficacious in lowering plasma LDL and non-HDL cholesterol in hypercholesterolemic type 2 diabetic and nondiabetic persons
    • Lau V.W., Journoud M., and Jones P.J. Plant sterols are efficacious in lowering plasma LDL and non-HDL cholesterol in hypercholesterolemic type 2 diabetic and nondiabetic persons. Am J Clin Nutr 81 (2005) 1351-1358
    • (2005) Am J Clin Nutr , vol.81 , pp. 1351-1358
    • Lau, V.W.1    Journoud, M.2    Jones, P.J.3
  • 57
    • 0037316361 scopus 로고    scopus 로고
    • Effects of policosanols and phytosterols on lipid levels and cholesterol biosynthesis in hamsters
    • Wang Y.W., Jones P.J., Pischel I., and Fairow C. Effects of policosanols and phytosterols on lipid levels and cholesterol biosynthesis in hamsters. Lipids 38 (2003) 165-170
    • (2003) Lipids , vol.38 , pp. 165-170
    • Wang, Y.W.1    Jones, P.J.2    Pischel, I.3    Fairow, C.4
  • 58
    • 0025305313 scopus 로고
    • Plasma membrane bleb formation and rupture: a common feature of hepatocellular injury
    • Gores G.J., Herman B., and Lemasters J.J. Plasma membrane bleb formation and rupture: a common feature of hepatocellular injury. Hepatology 11 (1990) 690-698
    • (1990) Hepatology , vol.11 , pp. 690-698
    • Gores, G.J.1    Herman, B.2    Lemasters, J.J.3
  • 59
    • 0030772958 scopus 로고    scopus 로고
    • How do plasma membranes reach the circulation?
    • Van Hoof V.O., Deng J.T., and De Broe M.E. How do plasma membranes reach the circulation?. Clin Chim Acta 266 (1997) 23-31
    • (1997) Clin Chim Acta , vol.266 , pp. 23-31
    • Van Hoof, V.O.1    Deng, J.T.2    De Broe, M.E.3
  • 60
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
    • Buse J.B., Klonoff D.C., Nielsen L.L., et al. Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials. Clin Ther 29 (2007) 139-153
    • (2007) Clin Ther , vol.29 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3
  • 61
    • 0028864517 scopus 로고
    • Enhanced biliary excretion of canalicular membrane enzymes in ethynylestradiol-induced cholestasis. Effects of ursodeoxycholic acid administration
    • Arrese M., Pizarro M., Solis N., Koenig C., and Accatino L. Enhanced biliary excretion of canalicular membrane enzymes in ethynylestradiol-induced cholestasis. Effects of ursodeoxycholic acid administration. Biochem Pharmacol 50 (1995) 1223-1232
    • (1995) Biochem Pharmacol , vol.50 , pp. 1223-1232
    • Arrese, M.1    Pizarro, M.2    Solis, N.3    Koenig, C.4    Accatino, L.5
  • 62
    • 0038466096 scopus 로고    scopus 로고
    • Induction of interleukin-12 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid, deviates CD4+ T cells from a Th2 to a Th1 response
    • Kim T.S., Kang B.Y., Cho D., and Kim S.H. Induction of interleukin-12 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid, deviates CD4+ T cells from a Th2 to a Th1 response. Immunology 109 (2003) 407-414
    • (2003) Immunology , vol.109 , pp. 407-414
    • Kim, T.S.1    Kang, B.Y.2    Cho, D.3    Kim, S.H.4
  • 63
    • 0037094342 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase in the induction of interleukin-12 p40 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid
    • Kang B.Y., Chung S.W., Cho D., and Kim T.S. Involvement of p38 mitogen-activated protein kinase in the induction of interleukin-12 p40 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid. Biochem Pharmacol 63 (2002) 1901-1910
    • (2002) Biochem Pharmacol , vol.63 , pp. 1901-1910
    • Kang, B.Y.1    Chung, S.W.2    Cho, D.3    Kim, T.S.4
  • 64
    • 0032985993 scopus 로고    scopus 로고
    • Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells
    • Fukuda K., Hibiya Y., Mutoh M., et al. Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol 66 (1999) 227-233
    • (1999) J Ethnopharmacol , vol.66 , pp. 227-233
    • Fukuda, K.1    Hibiya, Y.2    Mutoh, M.3
  • 65
    • 34250890634 scopus 로고    scopus 로고
    • Phytosterols as anticancer compounds
    • Bradford P.G., and Awad A.B. Phytosterols as anticancer compounds. Mol Nutr Food Res 51 (2007) 161-170
    • (2007) Mol Nutr Food Res , vol.51 , pp. 161-170
    • Bradford, P.G.1    Awad, A.B.2
  • 66
    • 0041917266 scopus 로고    scopus 로고
    • Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease
    • Kidd P. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern Med Rev 8 (2003) 223-246
    • (2003) Altern Med Rev , vol.8 , pp. 223-246
    • Kidd, P.1
  • 67
    • 0032466196 scopus 로고    scopus 로고
    • Gender effects of tall oil versus soybean phytosterols as cholesterol-lowering agents in hamsters
    • Ntanios F.Y., MacDougall D.E., and Jones P.J. Gender effects of tall oil versus soybean phytosterols as cholesterol-lowering agents in hamsters. Can J Physiol Pharmacol 76 (1998) 780-787
    • (1998) Can J Physiol Pharmacol , vol.76 , pp. 780-787
    • Ntanios, F.Y.1    MacDougall, D.E.2    Jones, P.J.3
  • 68
    • 4344624966 scopus 로고    scopus 로고
    • Phytosterols and cholesterol metabolism
    • Ostlund Jr. R.E. Phytosterols and cholesterol metabolism. Curr Opin Lipidol 15 (2004) 37-41
    • (2004) Curr Opin Lipidol , vol.15 , pp. 37-41
    • Ostlund Jr., R.E.1
  • 69
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw S., Nihal M., and Ahmad N. Dose translation from animal to human studies revisited. FASEB J 22 (2008) 659-661
    • (2008) FASEB J , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 70
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves P.G., Nielsen F.H., and Fahey Jr. G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123 (1993) 1939-1951
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.