-
1
-
-
20244371690
-
Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis
-
DOI 10.1053/j.gastro.2005.01.054
-
Mariadason JM, Nicholas C, L'Italien KE, et al. Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis. Gastroenterology 2005;128:1081-8. (Pubitemid 40523558)
-
(2005)
Gastroenterology
, vol.128
, Issue.4
, pp. 1081-1088
-
-
Mariadason, J.M.1
Nicholas, C.2
L'Italien, K.E.3
Zhuang, M.4
Smartt, H.J.M.5
Heerdt, B.G.6
Yang, W.7
Corner, G.A.8
Wilson, A.J.9
Klampfer, L.10
Arango, D.11
Augenlicht, L.H.12
-
2
-
-
34447094918
-
kip1 Regulates cdk2 Activity in the Proliferating Zone of the Mouse Intestinal Epithelium: Potential Role in Neoplasia
-
DOI 10.1053/j.gastro.2007.04.043, PII S0016508507008293
-
Smartt H, Guilmeau S, Nasser S, et al. p27kip1 regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia. Gastroenterology 2007;207: 232-43. (Pubitemid 47031132)
-
(2007)
Gastroenterology
, vol.133
, Issue.1
, pp. 232-243
-
-
Smartt, H.J.M.1
Guilmeau, S.2
Nasser, S.V.3
Nicholas, C.4
Bancroft, L.5
Simpson, S.A.6
Yeh, N.7
Yang, W.8
Mariadason, J.M.9
Koff, A.10
Augenlicht, L.H.11
-
3
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su L-K, Kinzler KW, Vogelstein B, et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256:668-70.
-
(1992)
Science
, vol.256
, pp. 668-670
-
-
Su, L.-K.1
Kinzler, K.W.2
Vogelstein, B.3
-
4
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R, Edelmann W, Yang K, et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci U S A 1994;91:8969-73.
-
(1994)
Proc Natl Acad Sci U S a
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
-
5
-
-
0028051822
-
Inactivation of both APC alleles in human and mouse tumors
-
Levy DB, Smith KJ, Beazer-Barclay Y, Hamilton SR, Vogelstein B, Kinzler KW. Inactivation of Both APC alleles in human and mouse tumors. Cancer Res 1994;54:5953-8. (Pubitemid 24375233)
-
(1994)
Cancer Research
, vol.54
, Issue.22
, pp. 5953-5958
-
-
Levy, D.B.1
Smith, K.J.2
Beazer-Barclay, Y.3
Hamilton, S.R.4
Vogelstein, B.5
Kinzler, K.W.6
-
6
-
-
0031568788
-
A mouse model of human familial adenomatous polyposis
-
Yang K, Edelmann W, Fan K, et al. A mouse model of human familial adenomatous polyposis. J Exp Zoolog 1997;277:245-54. (Pubitemid 27134192)
-
(1997)
Journal of Experimental Zoology
, vol.277
, Issue.3
, pp. 245-254
-
-
Yang, K.1
Edelmann, W.2
Fan, K.3
Lau, K.4
Kolli, V.R.5
Fodde, R.6
Khan, P.M.7
Kucherlapati, R.8
Lipkin, M.9
-
7
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M, Oshima H, Kitagawa K, et al. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci U S A 1995;92:4482-6.
-
(1995)
Proc Natl Acad Sci U S a
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
-
8
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG, Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 1971;68:820-3.
-
(1971)
Proc Natl Acad Sci U S A
, vol.68
, pp. 820-823
-
-
Knudson Jr., A.G.1
-
9
-
-
0021879645
-
Hereditary cancer, oncogenes and antioncogenes
-
Knudson AG. Hereditary cancer, oncogenes and antioncogenes. Cancer Res 1985;45:1437-43.
-
(1985)
Cancer Res
, vol.45
, pp. 1437-1443
-
-
Knudson, A.G.1
-
10
-
-
25444497707
-
The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis
-
DOI 10.1158/0008-5472.CAN-05-2145
-
Li Q, Ishikawa TO, Oshima M, Taketo MM. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis. Cancer Res 2005;65:8622-7. (Pubitemid 41377347)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8622-8627
-
-
Li, Q.1
Ishikawa, T.-O.2
Oshima, M.3
Taketo, M.M.4
-
11
-
-
0020645866
-
Tritiated thymidine (0(p),0(h)) labelling distribution as a marker for hereditary predisposition to colon cancer
-
Lipkin M, Blattner WE, Fraumeni JF, Lynch HT, Deschner E, Winawer S. Tritiated thymidine (0p,0h)labeling distribution as a marker for hereditary predisposition to colon cancer. Cancer Res 1983;43:1899-904. (Pubitemid 13122601)
-
(1983)
Cancer Research
, vol.43
, Issue.4
, pp. 1899-1904
-
-
Lipkin, M.1
Blattner, W.E.2
Fraumeni Jr., J.F.3
-
12
-
-
0344413420
-
Live and let die in the intestinal epithelium
-
DOI 10.1016/j.ceb.2003.10.012
-
Sancho E, Batlle E, Clevers H. Live and let die in the intestinal epithelium. Curr Opin Cell Biol 2003;15:763-70. (Pubitemid 37487970)
-
(2003)
Current Opinion in Cell Biology
, vol.15
, Issue.6
, pp. 763-770
-
-
Sancho, E.1
Batlle, E.2
Clevers, H.3
-
13
-
-
0035863515
-
Targeted inactivation of the p21 WAF1/cip1 gene enhances Apc initiated tumor formation and the tumor promoting activity of a Western-style high risk diet by altering cell maturation in the intestinal mucosa
-
Yang WC, Mathew J, Velcich A, et al. Targeted inactivation of the p21 WAF1/cip1 gene enhances Apc initiated tumor formation and the tumor promoting activity of a Western-style high risk diet by altering cell maturation in the intestinal mucosa. Cancer Res 2001;61: 565-9.
-
(2001)
Cancer Res
, vol.61
, pp. 565-569
-
-
Yang, W.C.1
Mathew, J.2
Velcich, A.3
-
14
-
-
24044542944
-
Gene expression profiling in single cells within tissue
-
DOI 10.1038/nmeth786
-
Capodieci P, Donovan M, Buchinsky H, et al. Gene expression profiling in single cells within tissue. Nat Methods 2005;2:663-5. (Pubitemid 41223092)
-
(2005)
Nature Methods
, vol.2
, Issue.9
, pp. 663-665
-
-
Capodieci, P.1
Donovan, M.2
Buchinsky, H.3
Jeffers, Y.4
Cordon-Cardo, C.5
Gerald, W.6
Edelson, J.7
Shenoy, S.M.8
Singer, R.H.9
-
16
-
-
0036827874
-
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention
-
Wilson AJ, Velcich A, Arango D, et al. Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. Cancer Res 2002;62:6006-10. (Pubitemid 35244443)
-
(2002)
Cancer Research
, vol.62
, Issue.21
, pp. 6006-6010
-
-
Wilson, A.J.1
Velcich, A.2
Arango, D.3
Kurland, A.R.4
Shenoy, S.M.5
Pezo, R.C.6
Levsky, J.M.7
Singer, R.H.8
Augenlicht, L.H.9
-
17
-
-
48549105218
-
Single-cell profiling of transcription site activation predicts chemotherapeutic response of human colorectal tumor cells
-
Pezo R, Gandhi S, Shirley L, Pestell R, Augenlicht L, Singer R. Single-cell profiling of transcription site activation predicts chemotherapeutic response of human colorectal tumor cells. Cancer Res 2008;68: 4977-82.
-
(2008)
Cancer Res
, vol.68
, pp. 4977-4982
-
-
Pezo, R.1
Gandhi, S.2
Shirley, L.3
Pestell, R.4
Augenlicht, L.5
Singer, R.6
-
18
-
-
58149375066
-
Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locusin colonic carcinoma cells
-
Maier S, Daroqui CM, Scherer S, et al. Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locusin colonic carcinoma cells. J Cell Physiol 2009;218:638-42.
-
(2009)
J Cell Physiol
, vol.218
, pp. 638-642
-
-
Maier, S.1
Daroqui, C.M.2
Scherer, S.3
-
21
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
DOI 10.1038/18884
-
Tetsu O, McCormick F. β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-6. (Pubitemid 29180374)
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
22
-
-
0033545845
-
The cyclin D1 gene is a target of the B-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the B-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A 1999;96:5522-7.
-
(1999)
Proc Natl Acad Sci U S a
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
-
23
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He T-C, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science 1998;281:1509-12.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.-C.1
Sparks, A.B.2
Rago, C.3
-
24
-
-
51249120100
-
Intestinal deletion of protein O-fucosyltransferase in the mouse inhibits Notch signaling and causes entero-colitis
-
Guilmeau S, Flandez M, Bancroft L, et al. Intestinal deletion of protein O-fucosyltransferase in the mouse inhibits Notch signaling and causes entero-colitis. Gastroenterology 2008;135:849-60.
-
(2008)
Gastroenterology
, vol.135
, pp. 849-860
-
-
Guilmeau, S.1
Flandez, M.2
Bancroft, L.3
-
26
-
-
0032535296
-
Dietary modulation of carcinoma development in a mouse model for human familial polyposis
-
Yang K, Edelmann W, Fan K, et al. Dietary modulation of carcinoma development in a mouse model for human familial polyposis. Cancer Res 1998;58:5713-7.
-
(1998)
Cancer Res
, vol.58
, pp. 5713-5717
-
-
Yang, K.1
Edelmann, W.2
Fan, K.3
-
27
-
-
54249154703
-
Dietary induction of colonic tumors in a mouse model of sporadic colon cancer
-
Yang K, Kurihara N, Fan K, et al. Dietary induction of colonic tumors in a mouse model of sporadic colon cancer. Cancer Res 2008;68: 7803-10.
-
(2008)
Cancer Res
, vol.68
, pp. 7803-7810
-
-
Yang, K.1
Kurihara, N.2
Fan, K.3
-
28
-
-
0042941403
-
Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a western-style high-risk diet
-
Yang W, Bancroft L, Nicholas C, Lozonschi I, Augenlicht LH. Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a western-style high-risk diet. Cancer Res 2003;63:4990-6.
-
(2003)
Cancer Res
, vol.63
, pp. 4990-4996
-
-
Yang, W.1
Bancroft, L.2
Nicholas, C.3
Lozonschi, I.4
Augenlicht, L.H.5
-
29
-
-
17144374133
-
Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- Mice
-
Yang W, Velcich A, Lozonschi I, et al. Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice. Am J Pathol 2005;166:1239-46.
-
(2005)
Am J Pathol
, vol.166
, pp. 1239-1246
-
-
Yang, W.1
Velcich, A.2
Lozonschi, I.3
-
30
-
-
77954377947
-
-
Website m. Available from
-
Website m. Available from: http://www.myccancergene.org/site/mycTargetDB. asp.
-
-
-
-
31
-
-
33846988274
-
Min/+ mouse
-
Ignatenko NA, Holubec H, Besselsen DG, et al. Role of c-Myc in intestinal tumorigenesis of the ApcMin/+ mouse. Cancer Biol Ther 2006;5:1658-64. (Pubitemid 46256645)
-
(2006)
Cancer Biology and Therapy
, vol.5
, Issue.12
, pp. 1658-1664
-
-
Ignatenko, N.A.1
Holubec, H.2
Besselsen, D.G.3
Blohm-Mangone, K.A.4
Padilla-Torres, J.L.5
Nagle, R.B.6
De Alboranc, I.M.7
Guillen-R, J.M.8
Gerner, E.W.9
-
32
-
-
34247187543
-
Myc deletion rescues Apc deficiency in the small intestine
-
DOI 10.1038/nature05674, PII NATURE05674
-
Sansom OJ, Meniel VS, Muncan V, et al. Myc deletion rescues Apc deficiency in the small intestine. Nature 2007;446:676-9. (Pubitemid 46606884)
-
(2007)
Nature
, vol.446
, Issue.7136
, pp. 676-679
-
-
Sansom, O.J.1
Meniel, V.S.2
Muncan, V.3
Phesse, T.J.4
Wilkins, J.A.5
Reed, K.R.6
Vass, J.K.7
Athineos, D.8
Clevers, H.9
Clarke, A.R.10
-
33
-
-
20544447734
-
Notch signals control the fate of immature progenitor cells in the intestine
-
DOI 10.1038/nature03589
-
Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S. Notch signals control the fate of immature progenitor cells in the intestine. Nature 2005;435:964-8. (Pubitemid 40896323)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 964-968
-
-
Fre, S.1
Huyghe, M.2
Mourikis, P.3
Robine, S.4
Louvard, D.5
Artavanis-Tsakonas, S.6
-
34
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
DOI 10.1126/science.1065718
-
Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 2001;294:2155-8. (Pubitemid 33150670)
-
(2001)
Science
, vol.294
, Issue.5549
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
35
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
DOI 10.1038/71657
-
Jensen J, Pedersen EE, Galante P, et al. Control of endodermal endocrine development by Hes-1. Nat Genet 2000;24:36-44. (Pubitemid 30041417)
-
(2000)
Nature Genetics
, vol.24
, Issue.1
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
36
-
-
37849022071
-
Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis
-
Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT. Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Mol Cell Biol 2008;28:718-31.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 718-731
-
-
Guzy, R.D.1
Sharma, B.2
Bell, E.3
Chandel, N.S.4
Schumacker, P.T.5
-
37
-
-
34247527730
-
Hypoxia-Inducible Factors, Stem Cells, and Cancer
-
DOI 10.1016/j.cell.2007.04.019, PII S0092867407005259
-
Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007;129:465-72. (Pubitemid 46660978)
-
(2007)
Cell
, vol.129
, Issue.3
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
38
-
-
0030703623
-
Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
-
Mahmoud NN, Boolbol SK, Bilinski RT, Martucci C, Chadburn A, Bertagnolli MM. Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration. Cancer Res 1997;57: 5045-50. (Pubitemid 27498118)
-
(1997)
Cancer Research
, vol.57
, Issue.22
, pp. 5045-5050
-
-
Mahmoud, N.N.1
Boolbol, S.K.2
Bilinski, R.T.3
Martucci, C.4
Chadburn, A.5
Bertagnolli, M.M.6
-
39
-
-
0033556002
-
Genotype-phenotype correlation in murine Apc mutation: Differences in enterocyte migration and response to sulindac
-
Mahmoud NN, Bilinski RT, Churchill MR, Edelmann W, Kucherlapati R, Bertagnolli MM. Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac. Cancer Res 1999;59:353-9.
-
(1999)
Cancer Res
, vol.59
, pp. 353-359
-
-
Mahmoud, N.N.1
Bilinski, R.T.2
Churchill, M.R.3
Edelmann, W.4
Kucherlapati, R.5
Bertagnolli, M.M.6
-
40
-
-
0031408413
-
Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis
-
Smits R, Kartheuser A, Jagmohan-Changur S, et al. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis 1997;18: 321-7.
-
(1997)
Carcinogenesis
, vol.18
, pp. 321-327
-
-
Smits, R.1
Kartheuser, A.2
Jagmohan-Changur, S.3
-
41
-
-
54649084868
-
Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: Potential role of chronic inflammation
-
Yang K, Popova N, Yang W, et al. Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. Cancer Res 2008;68:7313-22.
-
(2008)
Cancer Res
, vol.68
, pp. 7313-7322
-
-
Yang, K.1
Popova, N.2
Yang, W.3
-
42
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker N, Ridgway RA, van Es JH, et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 2009;457:608-11.
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
Van Es, J.H.3
-
43
-
-
0033405298
-
Short chain fatty acid metabolism, apoptosis and Apc initiated tumorigenesis in the mouse gastrointestinal mucosa
-
Augenlicht LH, Anthony GM, Chruch TL, et al. Short chain fatty acid metabolism, apoptosis and Apc initiated tumorigenesis in the mouse gastrointestinal mucosa. Cancer Res 1999;59:6005-9.
-
(1999)
Cancer Res
, vol.59
, pp. 6005-6009
-
-
Augenlicht, L.H.1
Anthony, G.M.2
Chruch, T.L.3
-
44
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek V, Barker N, Moerer P, et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998;19:379-83.
-
(1998)
Nat Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
-
45
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009;324:1029-33.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
46
-
-
0027443181
-
The role of hypoxia in the maintenance of hematopoietic stem cells
-
Cipolleschi MG, Dello Sbarba P, Olivotto M. The role of hypoxia in the maintenance of hematopoietic stem cells. Blood 1993;82: 2031-7.
-
(1993)
Blood
, vol.82
, pp. 2031-2037
-
-
Cipolleschi, M.G.1
Dello Sbarba, P.2
Olivotto, M.3
-
47
-
-
85047692887
-
Expansion of human SCID-repopulating cells under hypoxic conditions
-
DOI 10.1172/JCI200317669
-
Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 2003;112:126-35. (Pubitemid 38056384)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.1
, pp. 126-135
-
-
Danet, G.H.1
Pan, Y.2
Luongo, J.L.3
Bonnet, D.A.4
Simon, M.C.5
-
48
-
-
0034307432
-
Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells
-
Morrison SJ, Csete M, Groves AK, Melega W, Wold B, Anderson DJ. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells. J Neurosci 2000;20:7370-6.
-
(2000)
J Neurosci
, vol.20
, pp. 7370-7376
-
-
Morrison, S.J.1
Csete, M.2
Groves, A.K.3
Melega, W.4
Wold, B.5
Anderson, D.J.6
-
49
-
-
0034901617
-
Hypoxia-inducible factor and the development of stem cells of the cardiovascular system
-
Ramirez-Bergeron DL, Simon MC. Hypoxia-inducible factor and the development of stem cells of the cardiovascular system. Stem Cells 2001;19:279-86.
-
(2001)
Stem Cells
, vol.19
, pp. 279-286
-
-
Ramirez-Bergeron, D.L.1
Simon, M.C.2
-
50
-
-
0034307725
-
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
-
Studer L, Csete M, Lee SH, et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci 2000;20:7377-83.
-
(2000)
J Neurosci
, vol.20
, pp. 7377-7383
-
-
Studer, L.1
Csete, M.2
Lee, S.H.3
-
51
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
-
Pollard PJ, Briere JJ, Alam NA, et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations. Hum Mol Genet 2005;14: 2231-9.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
-
52
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
DOI 10.1038/sj.onc.1209594, PII 1209594
-
King A, Selak MA, Gottlieb E. Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. Oncogene 2006;25:4675-82. (Pubitemid 44187617)
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
53
-
-
33947520506
-
Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: Possible links between cellmetabolism and stabilization of HIF
-
Koivunen P, Hirsila M, Remes AM, Hassinen IE, Kivirikko KI, Myllyharju J. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cellmetabolism and stabilization of HIF. J Biol Chem 2007;282:4524-32.
-
(2007)
J Biol Chem
, vol.282
, pp. 4524-4532
-
-
Koivunen, P.1
Hirsila, M.2
Remes, A.M.3
Hassinen, I.E.4
Kivirikko, K.I.5
Myllyharju, J.6
-
54
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc Natl Acad Sci U S A 1998;95: 11715-20.
-
(1998)
Proc Natl Acad Sci U S a
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
55
-
-
67650480092
-
MTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
-
Shackelford DB, Vasquez DS, Corbeil J, et al. mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome. Proc Natl Acad Sci U S A 2009;106: 11137-42.
-
(2009)
Proc Natl Acad Sci U S a
, vol.106
, pp. 11137-11142
-
-
Shackelford, D.B.1
Vasquez, D.S.2
Corbeil, J.3
-
56
-
-
0037096906
-
The "just-right" signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade
-
Albuquerque C, Breukel C, van der Luijt R, et al. The "just-right" signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade. Hum Mol Genet 2002;11:1549-60.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
Van Der Luijt, R.3
-
57
-
-
40949105143
-
Further upregulation of {β}-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of Apc Min/+ mice
-
Oyama T, Yamada Y, Hata K, et al. Further upregulation of {β}-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of Apc Min/+ mice. Carcinogenesis 2008;29:666-72.
-
(2008)
Carcinogenesis
, vol.29
, pp. 666-672
-
-
Oyama, T.1
Yamada, Y.2
Hata, K.3
-
58
-
-
18744398990
-
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
-
Kielman MF, Rindapaa M, Gaspar C, et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling. Nat Genet 2002;32:594-605.
-
(2002)
Nat Genet
, vol.32
, pp. 594-605
-
-
Kielman, M.F.1
Rindapaa, M.2
Gaspar, C.3
-
59
-
-
0032428151
-
Modeling stochastic gene expression: Implications for haploinsufficiency
-
Cook DL, Gerber AN, Tapscott SJ. Modeling stochastic gene expression: implications for haploinsufficiency. Proc Natl Acad Sci U S A 1998;95:15641-6.
-
(1998)
Proc Natl Acad Sci U S a
, vol.95
, pp. 15641-15646
-
-
Cook, D.L.1
Gerber, A.N.2
Tapscott, S.J.3
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