Dietary induction of colonic tumors in a mouse model of sporadic colon cancer

Cancer Research

Volumn 68, Issue 19, 2008, Pages 7803-7810

  Yang, Kan ^a   Kurihara, Naoto ^a   Fan, Kunhua ^a   Newmark, Harold ^b   Rigas, Basil ^c   Bancroft, Laura ^d   Corner, Georgia ^d   Livote, Elayne ^e   Lesser, Martin ^e   Edelmann, Winfried ^d   Velcich, Anna ^d   Lipkin, Martin ^a   Augenlicht, Leonard ^d,f  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^f MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CALCIUM; CHOLINE; COLECALCIFEROL; FOLIC ACID; METHIONINE; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CALCIUM INTAKE; CANCER MODEL; CANCER RISK; CITRIC ACID CYCLE; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DIETARY FIBER; DOWN REGULATION; EPITHELIUM CELL; FEMALE; FOOD INTAKE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; LIFESPAN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VITAMIN INTAKE; WILD TYPE;

ANIMALS; CLUSTER ANALYSIS; COLONIC NEOPLASMS; DIET; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GENES, APC; INCIDENCE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUCIN-1; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

EID: 54249154703     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1209     Document Type: Article

References (44)

1. Slattery ML, Boucher KM, Caan BJ, Potter JD, Ma KN. Eating patterns and risk of colon cancer. Am J Epidemiol 1998;148:4-16.
2. Meyerhardt JA, Niedzwiecki D, Hollis D, et al. Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA 2007;298:754-64.
3. Potter JD. Risk factors for colon neoplasia-epidemiology and biology. Eur J Cancer 1995;31A:1033-8.
4. Newmark HL, Lipkin M, Maheshwari N. Colonic hyperplasia and hyperproliferation induced by a nutritional stress diet with four components of westen-style diet. J Nat Cancer Inst 1990;82:491-6.
5. Newmark HL, Lipkin M, Maheshwari N. Colonic hyperproliferation induced in rats and mice by nutritional-stress diets containing four components of a human western-style diet (series 2). Am J Clin Nutr 1991;54:209-14S.
6. Lipkin M, Yang K, Fan K, et al. Modulation of colonic lesions induced in Apc1638 mice by a western-style diet. Proc Am Assoc Cancer Res 1995;36:596.
7. Yang K, Edelmann W, Fan K, et al. Dietary modulation of carcinoma development in a mouse model for human familial polyposis. Cancer Res 1998;58:5713-7.
8. Yang WC, Mathew J, Velcich A, et al. Targeted inactivation of the p21 WAF1/cip1 gene enhances Apc initiated tumor formation and the tumor promoting activity of a Western-style high risk diet by altering cell maturation in the intestinal mucosa. Cancer Res 2001;61:565-9.
9. Yang W, Bancroft L, Nicholas C, Lozonschi I, Augenlicht LH. Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a western-style high-risk diet. Cancer Res 2003;63:4990-6.
10. Newmark HL, Yang K, Lipkin M, et al. A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice. Carcinogenesis 2001;22:1871-5.
11. Report of the American Institute of Nurtition ad hoc Committee on Standards for Nutritional Studies. J Nutr 1977;107:1340-8.
12. Bieri J. Second report of the ad hoc committee on standards for nutritional studies. J Nutr 1980;110:1726.
13. Newmark HL. Nutrient density: an important and useful tool for laboratory animal studies. Carcinogenesis 1987;8:871-3.
14. Yang K, Edelmann W, Fan K, et al. A mouse model of human familial adenomatous polyposis. J Exp Zool 1997;277:245-54.
15. Boivin GP, Washington K, Yang K, et al. Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology 2003;124:762-77.
16. Yang K, Edelmann W, Fan K, et al. Pathologic findings in gastrointestinal neoplasms of Apc1638 mice. 1994.
17. Velcich A, Yang W, Heyer J, et al. Colorectal cancer in mice genetically deficient in the mucin Muc2. Science 2002;295:1726-9.
18. Klampfer L, Huang J, Kaler P, Sasazuki T, Shirasawa S, Augenlicht L. STAT1-independent inhibition of cyclooxygenase-2 expression by IFNg;a common pathway of IFNγ-mediated gene repression but not gene activation. Oncogene 2007;26:2071-81.
19. Fleiss J. Statistical Methods for Rates and Proportions. 2nd ed. New York: Wiley; 1981.
20. Mckenzie D, Mackinnon A, Peladeau N, et al. Comparing correlated ns by resampling: is one level of agreement significantly different from another? J Psychiatric Res 1996;30:483-92.
21. Baron J, Beach M, Mandel R, et al. Calcium supplements for the prevention of colorectal adenomas. N Engl J Med 1999;340:101-7.
22. Grau MV, Baron JA, Sandler RS, et al. Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial. J Natl Cancer Inst 2003;95:1765-71.
23. Bonithon-Kopp C, Kronborg O, Giacosa A, Rath U, Faivre J; European Cancer Prevention Organisation Study Group. Calcium and fibre supplementation in prevention of colorectal adenoma recurrence: a randomised intervention trial. Lancet 2000;356:1300-6.
24. Lappe J, Travers-Gustafson D, Dvaies K, Recker R, Heaney R. Vitamin D and caclium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007;85:1586-91.
25. Grau MV, Baron JA, Sandler RS, et al. Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial. J Natl Cancer Inst 2007;99:129-36.
26. Wallace K, Baron JA, Cole BF, et al. Effect of calcium supplementation on the risk of large bowel polyps. J Natl Cancer Inst 2004;96:921-5.
27. Rundle AG, Lebwohl B, Vogel R, Levine S, Neugut AI. Colonoscopic screening in average-risk individuals ages 40 to 49 vs 50 to 59 years. Gastroenterology 2008;134:1311-5.
28. Fodde R, Edelmann W, Yang K, et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci US A 1994;91:8969-73.
29. Yang K, Popova N, Yang W, et al. Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. Cancer Res 2008;68:7313-22.
30. Oshima M, Oshima H, Kobayashi M, Tsutsumi M, Taketo MM. Evidence against dominant negative mechanisms of intestinal polyp formation by Apc gene mutations. Cancer Res 1995;55:2719-22.
31. Li Q, Ishikawa TO, Oshima M, Taketo MM. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis. Cancer Res 2005;65:8622-7.
32. Kim SY, Volsky DJ. PAGE: parametric analysis of gene set enrichment. BMC Bioinformatics 2005;6:144.
33. Kim SB, Yang S, Kim SK, et al. GAzer: gene set analyzer. Bioinformatics 2007;23:1697-9.
34. Warburg O. On respiratory impairment in cancer cells. Science 1956;124:269-70.
35. Thompson CB, Bauer DE, Lum JJ, et al. How do cancer cells acquire the fuel needed to support cell growth? Cold Spring Harb Symp Quant Biol 2005;70:357-62.
36. Gottlieb E, Tomlinson I. Mitochondrial tumor suppressors: a genetic and biochemical update. Nat Rev Cancer 2005;5:857-66.
37. Fantin VR, St-Pierre J, Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 2006;9:425-34.
38. Fearnhead NS, Wilding JL, Winney B, et al. Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci US A 2004;101:15992-7.
39. Fodde R. The multiple functions of tumour suppressors: its all in APC. Nat Cell Biol 2003;5:190-2.
40. Cook DL, Gerber AN, Tapscott SJ. Modeling stochastic gene expression: implications for haploinsufficiency. Proc Natl Acad Sci US A 1998;95:15641-6.
41. Mikol YB, Hoover KL, Creasia D, Poirier LA. Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets. Carcinogenesis 1983;4:1619-29.
42. Ghoshal AK, Farber E. The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens. Carcinogenesis 1984;5:1367-70.
43. Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci US A 1998;95:14863-8.
44. Dahlquist KD, Salomonis N, Vranizan K, Lawlor SC, Conklin BR. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 2002;31:19-20.