Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 3, 2009, Pages 387-393

  Reddy, Marpadga A ^a   Sahar, Saurabh ^a   Villeneuve, Louisa M ^a   Lanting, Linda ^a   Natarajan, Rama ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

12 15 lipoxygenase; Atherosclerosis; Histone acetylation; Inflammatory genes; Oxidized lipids; Src kinase; Vascular biology

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; GROWTH FACTOR; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; INTERLEUKIN 6; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; 12 15 LIPOXYGENASE; 12-15-LIPOXYGENASE; CCL2 PROTEIN, MOUSE; CCL2 PROTEIN, RAT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FOCAL ADHESION KINASE; HISTONE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

ACETYLATION; ANIMAL CELL; ARTICLE; ATHEROGENESIS; CELL MIGRATION; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPIGENETICS; GENE EXPRESSION; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; ANIMAL; ATHEROSCLEROSIS; C57BL MOUSE; CELL CULTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; INFLAMMATION; METABOLISM; MOUSE; MOUSE MUTANT; RAT; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT; TIME;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ACETYLATION; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; ATHEROSCLEROSIS; CELLS, CULTURED; CHEMOKINE CCL2; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME ACTIVATION; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION; HISTONES; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS; TRANSFECTION;

EID: 61549093719     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.179150     Document Type: Article

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