Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome

Journal of Immunology

Volumn 184, Issue 12, 2010, Pages 7092-7099

  Okuya, Koichi ^a   Tamura, Yasuaki ^a   Saito, Keita ^a   Kutomi, Goro ^a   Torigoe, Toshihiko ^a   Hirata, Koichi ^a   Sato, Noriyuki ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; DNA; EARLY ENDOSOME ANTIGEN 1; GAMMA INTERFERON; HEAT SHOCK PROTEIN 90; INTERFERON; RAB PROTEIN; TOLL LIKE RECEPTOR 9; AUTOANTIGEN; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; OLIGODEOXYRIBONUCLEOTIDE; TLR9 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER IMMUNOTHERAPY; CELL ISOLATION; CELL SELECTION; CELL STIMULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA DRUG COMPLEX; DNA ISOLATION; ENDOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOTHERAPY; INTERFERON INDUCTION; INTERFERON PRODUCTION; INTERNALIZATION; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN TARGETING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL SEPARATION; DENDRITIC CELL; IMMUNOLOGY; METABOLISM; PROTEIN TRANSPORT;

ANIMALS; AUTOANTIGENS; CELL SEPARATION; DENDRITIC CELLS; DNA; ENDOSOMES; FLOW CYTOMETRY; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN TRANSPORT; TOLL-LIKE RECEPTOR 9;

EID: 77953641046     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000490     Document Type: Article

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