-
2
-
-
0036512435
-
Multiple myeloma: Evolving genetic events and host interactions
-
Kuehl, W. M. and Bergsagel, P. L., Multiple myeloma: evolving genetic events and host interactions. Nat. Rev. Cancer 2002. 2: 175-187.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 175-187
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
3
-
-
0031985198
-
Multiple myeloma: Increasing evidence for a multistep transformation process
-
Hallek, M., Bergsagel, P. L. and Anderson, K. C., Multiple myeloma: increasing evidence for a multistep transformation process. Blood 1998. 91: 3-21
-
(1998)
Blood
, vol.91
, pp. 3-21
-
-
Hallek, M.1
Bergsagel, P.L.2
Anderson, K.C.3
-
4
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano, M., Hirano, T., Matsuda, T., Taga, T., Horii, Y., Iwato, K., Asaoku, H., Tang, B., Tanabe, O. and Tanaka, H., Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 1988. 332: 83-85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
Taga, T.4
Horii, Y.5
Iwato, K.6
Asaoku, H.7
Tang, B.8
Tanabe, O.9
Tanaka, H.10
-
5
-
-
0024503249
-
Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6
-
Klein, B., Zhang, X. G., Jourdan, M., Content, J., Houssiau, F., Aarden, L., Piechaczyk, M. and Bataille, R., Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6. Blood 1989. 73: 517-526.
-
(1989)
Blood
, vol.73
, pp. 517-526
-
-
Klein, B.1
Zhang, X.G.2
Jourdan, M.3
Content, J.4
Houssiau, F.5
Aarden, L.6
Piechaczyk, M.7
Bataille, R.8
-
6
-
-
0042008128
-
Survival and proliferation factors of normal and malignant plasma cells
-
Klein, B., Tarte, K., Jourdan, M., Mathouk, K., Moreaux, J., Jourdan, E., Legouffe, E., De Vos, J. and Rossi, J. F., Survival and proliferation factors of normal and malignant plasma cells. Int. J. Hematol. 2003. 78: 106-113
-
(2003)
Int. J. Hematol.
, vol.78
, pp. 106-113
-
-
Klein, B.1
Tarte, K.2
Jourdan, M.3
Mathouk, K.4
Moreaux, J.5
Jourdan, E.6
Legouffe, E.7
De Vos, J.8
Rossi, J.F.9
-
7
-
-
0034517587
-
The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma
-
Barille, S., Bataille, R. and Amiot, M., The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma. Eur. Cytokine Netw 2000. 11: 546-551.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 546-551
-
-
Barille, S.1
Bataille, R.2
Amiot, M.3
-
8
-
-
0028282852
-
Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma
-
Zhang, X. G., Gaillard, J. P., Robillard, N., Lu, Z. Y., Gu, Z. J., Jourdan, M., Boiron, J. M., Bataille, R. and Klein, B., Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma. Blood 1994. 83: 3654-3663.
-
(1994)
Blood
, vol.83
, pp. 3654-3663
-
-
Zhang, X.G.1
Gaillard, J.P.2
Robillard, N.3
Lu, Z.Y.4
Gu, Z.J.5
Jourdan, M.6
Boiron, J.M.7
Bataille, R.8
Klein, B.9
-
9
-
-
0033971174
-
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors
-
Gu, Z. J., De Vos, J., Rebouissou, C., Jourdan, M., Zhang, X. G., Rossi, J. F., Wijdenes, J. and Klein, B., Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors. Leukemia 2000. 14: 188-197.
-
(2000)
Leukemia
, vol.14
, pp. 188-197
-
-
Gu, Z.J.1
De Vos, J.2
Rebouissou, C.3
Jourdan, M.4
Zhang, X.G.5
Rossi, J.F.6
Wijdenes, J.7
Klein, B.8
-
10
-
-
0033861096
-
JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells
-
De Vos, J., Jourdan, M., Tarte, K., Jasmin, C. and Klein, B., JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells. Br. J. Haematol 2000. 109: 823-828.
-
(2000)
Br. J. Haematol
, vol.109
, pp. 823-828
-
-
De Vos, J.1
Jourdan, M.2
Tarte, K.3
Jasmin, C.4
Klein, B.5
-
11
-
-
0032711250
-
IL-6 upregulates Mcl-1 in human myeloma cells through JAK/STAT rather than Ras/MAP kinase pathway
-
Puthier, D., Bataille, R. and Amiot, M., IL-6 upregulates Mcl-1 in human myeloma cells through JAK/STAT rather than Ras/MAP kinase pathway. Eur. J. Immunol 1999. 29: 3945-3950.
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 3945-3950
-
-
Puthier, D.1
Bataille, R.2
Amiot, M.3
-
12
-
-
0033179760
-
Bcl-2 family members and the mitochondria in apoptosis
-
Gross, A., McDonnell, J. M. and Korsmeyer, S. J., Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 1999. 13: 1899-1911.
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, J.M.3
-
13
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory, S., Huang, D. C. and Adams, J. M., The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003. 22: 8590-8607.
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
14
-
-
0036659905
-
Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells
-
Derenne, S., Monia, B., Dean, N. M., Taylor, J. K., Rapp, M. J., Harousseau, J. L., Bataille, R. and Amiot, M., Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells. Blood 2002. 100: 194-199.
-
(2002)
Blood
, vol.100
, pp. 194-199
-
-
Derenne, S.1
Monia, B.2
Dean, N.M.3
Taylor, J.K.4
Rapp, M.J.5
Harousseau, J.L.6
Bataille, R.7
Amiot, M.8
-
15
-
-
0037085778
-
Myeloid cell factor-1 is a critical survival factor for multiple myeloma
-
Zhang, B., Gojo, I. and Fenton, R. G., Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood 2002. 99: 1885-1893.
-
(2002)
Blood
, vol.99
, pp. 1885-1893
-
-
Zhang, B.1
Gojo, I.2
Fenton, R.G.3
-
16
-
-
0038021146
-
A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells
-
Jourdan, M., Veyrune, J. L., Vos, J. D., Redal, N., Couderc, G. and Klein, B., A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells. Oncogene 2003. 22: 2950-2959.
-
(2003)
Oncogene
, vol.22
, pp. 2950-2959
-
-
Jourdan, M.1
Veyrune, J.L.2
Vos, J.D.3
Redal, N.4
Couderc, G.5
Klein, B.6
-
17
-
-
0033635733
-
BH3-only proteins - Essential initiators of apoptotic cell death
-
Huang, D. C. and Strasser, A., BH3-only proteins - essential initiators of apoptotic cell death. Cell 2000. 103: 839-842.
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.1
Strasser, A.2
-
18
-
-
0036097786
-
Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath, H. and Strasser, A., Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002. 9: 505-512.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
19
-
-
0032161337
-
BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members
-
Hsu, S. Y., Lin, P. and Hsueh, A. J., BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endocrinol 1998. 12: 1432-1440.
-
(1998)
Mol. Endocrinol.
, vol.12
, pp. 1432-1440
-
-
Hsu, S.Y.1
Lin, P.2
Hsueh, A.J.3
-
20
-
-
0032518787
-
Bim: A novel member of the Bcl-2 family that promotes apoptosis
-
O'Connor, L., Strasser, A., O'Reilly, L. A., Hausmann, G., Adams, J. M., Cory, S. and Huang, D. C., Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998. 17: 384-395.
-
(1998)
EMBO J.
, vol.17
, pp. 384-395
-
-
O'Connor, L.1
Strasser, A.2
O'Reilly, L.A.3
Hausmann, G.4
Adams, J.M.5
Cory, S.6
Huang, D.C.7
-
21
-
-
0033104996
-
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
Puthalakath, H., Huang, D. C., O'Reilly, L. A., King, S. M. and Strasser, A., The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol. Cell 1999. 3: 287-296.
-
(1999)
Mol. Cell
, vol.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.2
O'Reilly, L.A.3
King, S.M.4
Strasser, A.5
-
22
-
-
0035135349
-
Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors
-
Shinjyo, T., Kuribara, R., Inukai, T., Hosoi, H., Kinoshita, T., Miyajima, A., Houghton, P. J., Look, A. T., Ozawa, K. and Inaba, T., Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol. Cell. Biol 2001. 21: 854-864.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 854-864
-
-
Shinjyo, T.1
Kuribara, R.2
Inukai, T.3
Hosoi, H.4
Kinoshita, T.5
Miyajima, A.6
Houghton, P.J.7
Look, A.T.8
Ozawa, K.9
Inaba, T.10
-
23
-
-
0037443492
-
Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival
-
Villunger, A., Scott, C., Bouillet, P. and Strasser, A., Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival. Blood 2003. 101: 2393-2400.
-
(2003)
Blood
, vol.101
, pp. 2393-2400
-
-
Villunger, A.1
Scott, C.2
Bouillet, P.3
Strasser, A.4
-
24
-
-
0035053624
-
Induction of Bim, a proapoptotic BH3-only Bcl-2 family member, is critical for neuronal apoptosis
-
Putcha, G. V., Moulder, K. L., Golden, J. P., Bouillet, P., Adams, J. A., Strasser, A. and Johnson, E. M., Induction of Bim, a proapoptotic BH3-only Bcl-2 family member, is critical for neuronal apoptosis. Neuron 2001. 29: 615-628.
-
(2001)
Neuron.
, vol.29
, pp. 615-628
-
-
Putcha, G.V.1
Moulder, K.L.2
Golden, J.P.3
Bouillet, P.4
Adams, J.A.5
Strasser, A.6
Johnson, E.M.7
-
25
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet, P., Metcalf, D., Huang, D. C., Tarlinton, D. M., Kay, T. W., Kontgen, F., Adams, J. M. and Strasser, A., Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999. 286: 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
Tarlinton, D.M.4
Kay, T.W.5
Kontgen, F.6
Adams, J.M.7
Strasser, A.8
-
26
-
-
0035977077
-
Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family
-
U,M
-
U, M., Miyashita, T., Shikama, Y., Tadokoro, K. and Yamada, M., Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family. FEBS Lett 2001. 509: 135-141.
-
(2001)
FEBS Lett.
, vol.509
, pp. 135-141
-
-
Miyashita, T.1
Shikama, Y.2
Tadokoro, K.3
Yamada, M.4
-
27
-
-
0037092570
-
Identification and characterization of Bim gamma, a novel proapoptotic BH3-only splice variant of Bim
-
Liu, J. W., Chandra, D., Tang, S. H., Chopra, D. and Tang, D. G., Identification and characterization of Bim gamma, a novel proapoptotic BH3-only splice variant of Bim. Cancer Res 2002. 62: 2976-2981.
-
(2002)
Cancer Res.
, vol.62
, pp. 2976-2981
-
-
Liu, J.W.1
Chandra, D.2
Tang, S.H.3
Chopra, D.4
Tang, D.G.5
-
28
-
-
0242521470
-
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
-
Luciano, F., Jacquel, A., Colosetti, P., Herrant, M., Cagnol, S., Pages, G. and Auberger, P., Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 2003. 22: 6785-6793.
-
(2003)
Oncogene
, vol.22
, pp. 6785-6793
-
-
Luciano, F.1
Jacquel, A.2
Colosetti, P.3
Herrant, M.4
Cagnol, S.5
Pages, G.6
Auberger, P.7
-
29
-
-
0036830438
-
L protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL
-
L protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL. J. Biol. Chem 2002. 277: 41604-41612.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41604-41612
-
-
Yamaguchi, H.1
Wang, H.G.2
-
30
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome C
-
Wei, M. C., Lindsten, T., Mootha, V. K., Weiler, S., Gross, A., Ashiya, M., Thompson, C. B. and Korsmeyer S. J., tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome C. Genes Dev 2000. 14: 2060-2071.
-
(2000)
Genes Dev.
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
31
-
-
2442656629
-
Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells
-
Zhu, Y., Swanson, B. J., Wang, M., Hildeman, D. A., Schaefer, B. C., Liu, X., Suzuki, H., Milhara, K., Kappler, J. and Marrack, P., Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc. Natl. Acad. Sci. USA 2004. 101: 7681-7686.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7681-7686
-
-
Zhu, Y.1
Swanson, B.J.2
Wang, M.3
Hildeman, D.A.4
Schaefer, B.C.5
Liu, X.6
Suzuki, H.7
Milhara, K.8
Kappler, J.9
Marrack, P.10
-
32
-
-
0030033049
-
Expression of the Bcl-2 homologue Mcl-1 correlates with survival of peripheral blood B lymphocytes
-
Lomo, J., Smeland, E. B., Krajewski, S., Reed, J. C. and Blomhoff, H. K., Expression of the Bcl-2 homologue Mcl-1 correlates with survival of peripheral blood B lymphocytes. Cancer Res. 1996. 56: 40-43.
-
(1996)
Cancer Res.
, vol.56
, pp. 40-43
-
-
Lomo, J.1
Smeland, E.B.2
Krajewski, S.3
Reed, J.C.4
Blomhoff, H.K.5
-
33
-
-
0035876931
-
Cooperative regulation of Mcl-1 by Janus kinase/STAT and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils
-
Epling-Burnette, P. K., Zhong, B., Bai, F., Jiang, K., Bailey, R. D., Garcia, R., Jove, R., Djeu, J. Y., Loughran, T. P. Jr. and Wei, S., Cooperative regulation of Mcl-1 by Janus kinase/STAT and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils. J. Immunol. 2001. 166: 7486-7495.
-
(2001)
J. Immunol.
, vol.166
, pp. 7486-7495
-
-
Epling-Burnette, P.K.1
Zhong, B.2
Bai, F.3
Jiang, K.4
Bailey, R.D.5
Garcia, R.6
Jove, R.7
Djeu, J.Y.8
Loughran Jr., T.P.9
Wei, S.10
-
34
-
-
0035825596
-
The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6
-
Kuo, M. L., Chuang, S. E., Lin, M. T. and Yang, S. Y., The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogrene 2001. 20: 677-685.
-
(2001)
Oncogrene
, vol.20
, pp. 677-685
-
-
Kuo, M.L.1
Chuang, S.E.2
Lin, M.T.3
Yang, S.Y.4
-
35
-
-
0038393112
-
Apoptosis in the development and maintenance of the immune system
-
Opferman, J. T. and Korsmeyer, S. J., Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 2003. 4: 410-415.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 410-415
-
-
Opferman, J.T.1
Korsmeyer, S.J.2
-
36
-
-
0034525417
-
Regulation of Bcl-2 family proteins in myeloma cells by three myeloma survival factors: Interleukin-6, interferon-alpha and insulin-like growth factor 1
-
Jourdan, M., De Vos, J., Mechti N. and Klein, B., Regulation of Bcl-2 family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1. Cell Death Differ 2000. 7: 1244-1252.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1244-1252
-
-
Jourdan, M.1
De Vos, J.2
Mechti, N.3
Klein, B.4
-
37
-
-
0037592259
-
Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis
-
Wang, Z., Malone, M. H., He, H., McColl, K. S. and Distelhorst, C. W., Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J. Biol. Chem 2003. 278: 23861-23867.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23861-23867
-
-
Wang, Z.1
Malone, M.H.2
He, H.3
McColl, K.S.4
Distelhorst, C.W.5
-
38
-
-
0038046166
-
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
-
Nijhawan, D., Fang, M., Traer, E., Zhong, Q., Gao, W., Du, F. and Wang, X., Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev 2003. 17: 1475-1486.
-
(2003)
Genes Dev.
, vol.17
, pp. 1475-1486
-
-
Nijhawan, D.1
Fang, M.2
Traer, E.3
Zhong, Q.4
Gao, W.5
Du, F.6
Wang, X.7
-
39
-
-
0348014686
-
DNA damage response and Mcl-1 destruction initiate apoptosis in adenovirus-infected cells
-
Cuconati, A., Mukherjee, C., Perez, D. and White, E., DNA damage response and Mcl-1 destruction initiate apoptosis in adenovirus-infected cells. Genes Dev 2003. 17: 2922-2932.
-
(2003)
Genes Dev.
, vol.17
, pp. 2922-2932
-
-
Cuconati, A.1
Mukherjee, C.2
Perez, D.3
White, E.4
-
40
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet, P., Purton, J. F., Godfrey, D. I., Zhang, L. C., Coultas, L., Puthalakath, H., Pellegrini, M., Cory, S., Adams, J. M. and Strasser, A., BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 2002. 415: 922-926.
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
Purton, J.F.2
Godfrey, D.I.3
Zhang, L.C.4
Coultas, L.5
Puthalakath, H.6
Pellegrini, M.7
Cory, S.8
Adams, J.M.9
Strasser, A.10
-
41
-
-
0034786019
-
Bcl-2, Bcl-x(L) sequester BH3 domain-only molecules preventing Bax- and Bak-mediated mitochondrial apoptosis
-
Cheng, E. H., Wei, M. C., Weiler, S., Flavell, R. A., Mak, T. W., Lindsten, T. and Korsmeyer, S. J., Bcl-2, Bcl-x(L) sequester BH3 domain-only molecules preventing Bax- and Bak-mediated mitochondrial apoptosis. Mol. Cell 2001. 8: 705-711.
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
42
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong, W. X., Lindsten, T., Ross, A. J., MacGregor, G. R. and Thompson, C. B., BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001. 15: 1481-1486.
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
43
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S. and Korsmeyer, S. J., Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2002. 2: 183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
44
-
-
0036069819
-
Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim
-
Hildeman, D. A., Zhu, Y., Mitchell, T. C., Bouillet, P., Strasser, A., Kappler, J. and Marrack, P., Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim. Immunity 2002. 16: 759-767.
-
(2002)
Immunity
, vol.16
, pp. 759-767
-
-
Hildeman, D.A.1
Zhu, Y.2
Mitchell, T.C.3
Bouillet, P.4
Strasser, A.5
Kappler, J.6
Marrack, P.7
-
45
-
-
0142245593
-
Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels
-
van de Donk, N. W., Kamphuis, M. M., van Kessel, B., Lokhorst, H. M. and Bloem, A. C., Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels. Blood 2003. 102: 3354-3362.
-
(2003)
Blood
, vol.102
, pp. 3354-3362
-
-
van de Donk, N.W.1
Kamphuis, M.M.2
van Kessel, B.3
Lokhorst, H.M.4
Bloem, A.C.5
-
46
-
-
0036850211
-
The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1
-
Gojo, I., Zhang, B. and Fenton, R. G., The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1. Clin. Cancer Res 2002. 8: 3527-3538.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3527-3538
-
-
Gojo, I.1
Zhang, B.2
Fenton, R.G.3
-
47
-
-
0041822678
-
Guardians of cell death: The Bcl-2 family proteins
-
Daniel, P. T., Schulze-Osthoff, K., Belka, C. and Guner, D., Guardians of cell death: the Bcl-2 family proteins. Essays Biochem 2003. 39: 73-88.
-
(2003)
Essays Biochem.
, vol.39
, pp. 73-88
-
-
Daniel, P.T.1
Schulze-Osthoff, K.2
Belka, C.3
Guner, D.4
-
49
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
Tzung, S. P., Kim, K. M., Basanez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y. and Hockenbery, D. M., Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat. Cell Biol 2001. 3: 183-191.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 183-191
-
-
Tzung, S.P.1
Kim, K.M.2
Basanez, G.3
Giedt, C.D.4
Simon, J.5
Zimmerberg, J.6
Zhang, K.Y.7
Hockenbery, D.M.8
-
50
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a JAK-2 inhibitor
-
Meydan, N., Grunberger, T., Dadi, H., Sahar, M., Arpaia, E., Lapidot, Z., Leeder, J. S., Freedman, M., Cohen, A., Gazit, A. and Roifman, C. M., Inhibition of acute lymphoblastic leukaemia by a JAK-2 inhibitor. Nature 1996. 379: 645-648.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
Sahar, M.4
Arpaia, E.5
Lapidot, Z.6
Leeder, J.S.7
Freedman, M.8
Cohen, A.9
Gazit, A.10
Roifman, C.M.11
|