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Volumn 1, Issue 3, 2009, Pages 435-445

Joint injury and osteoarthritis: Soluble mediators in the course and treatment of cartilage pathology

Author keywords

Cartilage; Cytokine; Intra articular trauma; Osteoarthritis; Synovial fluid

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; OSTEOPROTEGERIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 77953462201     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.09.14     Document Type: Review
Times cited : (15)

References (153)
  • 1
    • 0001287304 scopus 로고    scopus 로고
    • Cell-mediated immune reactions
    • Crowe L (Ed.). Mosby, London, UK
    • Roitt IM, Brostoff J, Male DK: Cell-mediated immune reactions. In: Immunology. Crowe L (Ed.). Mosby, London, UK 121-138 (2001).
    • (2001) Immunology , pp. 121-138
    • Roitt, I.M.1    Brostoff, J.2    Male, D.K.3
  • 2
    • 34548567002 scopus 로고    scopus 로고
    • Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans
    • Garlet TP, Coelho U, Silva JS, Garlet GP: Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans. Eur. J. Oral Sci. 115(5), 355-362 (2007).
    • (2007) Eur. J. Oral Sci. , vol.115 , Issue.5 , pp. 355-362
    • Garlet, T.P.1    Coelho, U.2    Silva, J.S.3    Garlet, G.P.4
  • 3
    • 49449085034 scopus 로고    scopus 로고
    • Cytokines that promote periodontal tissue destruction
    • Graves D: Cytokines that promote periodontal tissue destruction. J. Periodontol. 79(Suppl. 8), 1585-1591 (2008).
    • (2008) J. Periodontol. , vol.79 , Issue.SUPPL. 8 , pp. 1585-1591
    • Graves, D.1
  • 4
    • 0034945450 scopus 로고    scopus 로고
    • Role of cytokines and cytokine therapy in wound healing and fibrotic diseases
    • Gharaee-Kermani M, Phan SH: Role of cytokines and cytokine therapy in wound healing and fibrotic diseases. Curr. Pharm. Des. 7(11), 1083-1103 (2001).
    • (2001) Curr. Pharm. Des. , vol.7 , Issue.11 , pp. 1083-1103
    • Gharaee-Kermani, M.1    Phan, S.H.2
  • 5
    • 28044433678 scopus 로고    scopus 로고
    • Role of cytokines and chemokines in pseudomonal keratitis
    • Matsumoto K, Ikema K, Tanihara H: Role of cytokines and chemokines in pseudomonal keratitis. Cornea 24(Suppl. 8), S43-S49 (2005). (Pubitemid 41688555)
    • (2005) Cornea , vol.24 , Issue.8 SUPPL.
    • Matsumoto, K.1    Ikema, K.2    Tanihara, H.3
  • 7
    • 5444259084 scopus 로고    scopus 로고
    • The regulation of chondrocyte function by proinflammatory mediators: Prostaglandins and nitric oxide
    • Goldring MB, Berenbaum F: The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide. Clin. Orthop. Relat. Res. (Suppl 427), S37-S46 (2004).
    • (2004) Clin. Orthop. Relat. Res. , Issue.SUPPL. 427
    • Goldring, M.B.1    Berenbaum, F.2
  • 8
    • 5444238022 scopus 로고    scopus 로고
    • The role of cytokines in cartilage matrix degeneration in osteoarthritis
    • Excellent review on the role of a variety of cytokines in cartilage damage and repair
    • Goldring SR, Goldring MB: The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin. Orthop. Relat. Res. (Suppl. 427), S27-36 (2004). ■■ Excellent review on the role of a variety of cytokines in cartilage damage and repair.
    • (2004) Clin. Orthop. Relat. Res. , Issue.SUPPL. 427
    • Goldring, S.R.1    Goldring, M.B.2
  • 9
    • 0002440327 scopus 로고    scopus 로고
    • Articular cartilage structure, composition, and function
    • American Academy of Orthopaedic Surgeons, Rosemont, IL, USA Comprehensive reference work on composition and biomechanical properties of cartilage
    • Buckwalter JA, Einhorn TA, Simon SB: Articular cartilage structure, composition, and function. In: Orthopaedic Basic Science. American Academy of Orthopaedic Surgeons, Rosemont, IL, USA 444-451 (1999). ■ Comprehensive reference work on composition and biomechanical properties of cartilage.
    • (1999) Orthopaedic Basic Science , pp. 444-451
    • Buckwalter, J.A.1    Einhorn, T.A.2    Simon, S.B.3
  • 10
    • 0024581748 scopus 로고
    • Some recombinant human cytokines stimulate glycosaminoglycan synthesis in human synovial fibroblast cultures and inhibit it in human articular cartilage cultures
    • DOI 10.1002/anr.1780320210
    • Yaron I, Meyer FA, Dayer JM, Bleiberg I, Yaron M: Some recombinant human cytokines stimulate glycosaminoglycan synthesis in human synovial fibroblast cultures and inhibit it in human articular cartilage cultures. Arthritis Rheum. 32(2), 173-180 (1989). (Pubitemid 19056405)
    • (1989) Arthritis and Rheumatism , vol.32 , Issue.2 , pp. 173-180
    • Yaron, I.1    Meyer, F.A.2    Dayer, J.-M.3    Bleiberg, I.4    Yaron, M.5
  • 11
    • 0024210874 scopus 로고
    • Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes
    • Goldring MB, Birkhead J, Sandell LJ, Kimura T, Krane SM: Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J. Clin. Invest. 82(6), 2026-2037 (1988).
    • (1988) J. Clin. Invest. , vol.82 , Issue.6 , pp. 2026-2037
    • Goldring, M.B.1    Birkhead, J.2    Sandell, L.J.3    Kimura, T.4    Krane, S.M.5
  • 12
    • 0029895089 scopus 로고    scopus 로고
    • Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies
    • Schlaak JF, Pfers I, Meyer Zum Buschenfelde KH, Marker-Hermann E: Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies. Clin. Exp. Rheumatol. 14(2), 155-162 (1996).
    • (1996) Clin. Exp. Rheumatol. , vol.14 , Issue.2 , pp. 155-162
    • Schlaak, J.F.1    Pfers, I.2    Meyer Zum Buschenfelde, K.H.3    Marker-Hermann, E.4
  • 13
    • 0025120445 scopus 로고
    • Synovial fluid concentration of five different cytokines in rheumatic diseases
    • Westacott CI, Whicher JT, Barnes IC et al.: Synovial fluid concentration of five different cytokines in rheumatic diseases. Ann. Rheum. Dis. 49(9), 676-681 (1990).
    • (1990) Ann. Rheum. Dis. , vol.49 , Issue.9 , pp. 676-681
    • Westacott, C.I.1    Whicher, J.T.2    Barnes, I.C.3
  • 14
    • 0025675717 scopus 로고
    • Interleukin 1 β in synovial fluid is related to local disease activity in rheumatoid arthritis
    • Rooney M, Symons JA, Duff GW: Interleukin 1 β in synovial fluid is related to local disease activity in rheumatoid arthritis. Rheumatol. Int. 10(5), 217-219 (1990).
    • (1990) Rheumatol. Int. , vol.10 , Issue.5 , pp. 217-219
    • Rooney, M.1    Symons, J.A.2    Duff, G.W.3
  • 15
    • 3442885115 scopus 로고    scopus 로고
    • A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret®), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate
    • Cohen SB, Moreland LW, Cush JJ et al.: A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret®), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann. Rheum. Dis. 63(9), 1062-1068 (2004).
    • (2004) Ann. Rheum. Dis. , vol.63 , Issue.9 , pp. 1062-1068
    • Cohen, S.B.1    Moreland, L.W.2    Cush, J.J.3
  • 16
    • 33646464514 scopus 로고    scopus 로고
    • Etanercept treatment in adults with established rheumatoid arthritis: 7 years of clinical experience
    • Moreland LW, Weinblatt ME, Keystone EC et al.: Etanercept treatment in adults with established rheumatoid arthritis: 7 years of clinical experience. J. Rheumatol. 33(5), 854-861 (2006).
    • (2006) J. Rheumatol. , vol.33 , Issue.5 , pp. 854-861
    • Moreland, L.W.1    Weinblatt, M.E.2    Keystone, E.C.3
  • 17
    • 34447300492 scopus 로고    scopus 로고
    • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): Evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
    • Nishimoto N, Hashimoto J, Miyasaka N et al.: Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann. Rheum. Dis. 66(9), 1162-1167 (2007).
    • (2007) Ann. Rheum. Dis. , vol.66 , Issue.9 , pp. 1162-1167
    • Nishimoto, N.1    Hashimoto, J.2    Miyasaka, N.3
  • 19
    • 0024986801 scopus 로고
    • The role of cytokines in the development of osteoarthritis
    • Loyau G, Pujol JP: The role of cytokines in the development of osteoarthritis. Scand. J. Rheumatol. (Suppl. 81) 8-12 (1990).
    • (1990) Scand. J. Rheumatol. , Issue.SUPPL. 81 , pp. 8-12
    • Loyau, G.1    Pujol, J.P.2
  • 20
    • 52649120855 scopus 로고    scopus 로고
    • Osteoarthritis and rheumatoid arthritis pannus have similar qualitative metabolic characteristics and pro-inflammatory cytokine response
    • Furuzawa-Carballeda J, Macip-Rodriguez PM, Cabrai AR: Osteoarthritis and rheumatoid arthritis pannus have similar qualitative metabolic characteristics and pro-inflammatory cytokine response. Clin. Exp. Rheumatol. 26(4), 554-560 (2008).
    • (2008) Clin. Exp. Rheumatol. , vol.26 , Issue.4 , pp. 554-560
    • Furuzawa-Carballeda, J.1    Macip-Rodriguez, P.M.2    Cabrai, A.R.3
  • 21
    • 54049126553 scopus 로고    scopus 로고
    • T cells in rheumatoid arthritis
    • Cope AP: T cells in rheumatoid arthritis. Arthritis Res. Ther. (10 Suppl. 1) S1 (2008).
    • (2008) Arthritis Res. Ther. , Issue.10 SUPPL. 1
    • Cope, A.P.1
  • 22
    • 0034609563 scopus 로고    scopus 로고
    • Joint injury in young adults and risk for subsequent knee and hip osteoarthritis
    • Gelber AC, Hochberg MC, Mead LA et al.: Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann. Intern. Med. 133(5), 321-328 (2000).
    • (2000) Ann. Intern. Med. , vol.133 , Issue.5 , pp. 321-328
    • Gelber, A.C.1    Hochberg, M.C.2    Mead, L.A.3
  • 24
    • 0031019995 scopus 로고    scopus 로고
    • Partial meniscectomy and osteoarthritis. Implications for treatment of athletes
    • Rangger C, Kathrein A, Klestil T, Glotzer W: Partial meniscectomy and osteoarthritis. Implications for treatment of athletes. Sports Med. 23(1), 61-68 (1997).
    • (1997) Sports Med. , vol.23 , Issue.1 , pp. 61-68
    • Rangger, C.1    Kathrein, A.2    Klestil, T.3    Glotzer, W.4
  • 26
    • 0024528781 scopus 로고
    • Induction of articular cartilage degradation by recombinant interleukin 1 α and 1 β
    • Smith RL, Allison AC, Schurman DJ: Induction of articular cartilage degradation by recombinant interleukin 1 α and 1 β. Connect Tissue Res. 18(4), 307-316 (1989).
    • (1989) Connect Tissue Res. , vol.18 , Issue.4 , pp. 307-316
    • Smith, R.L.1    Allison, A.C.2    Schurman, D.J.3
  • 27
    • 0000609002 scopus 로고
    • Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint
    • Pettipher ER, Higgs GA, Henderson B: Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc. Natl. Acad. Sci. U.S.A. 83(22), 8749-8753 (1986).
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , Issue.22 , pp. 8749-8753
    • Pettipher, E.R.1    Higgs, G.A.2    Henderson, B.3
  • 28
    • 0034124588 scopus 로고    scopus 로고
    • Tumor necrosis factor α can contribute to focal loss of cartilage in osteoarthritis
    • Westacott CI, Barakat AF, Wood L et al.: Tumor necrosis factor α can contribute to focal loss of cartilage in osteoarthritis. Osteoarthr. Cartil. 8(3), 213-221 (2000).
    • (2000) Osteoarthr. Cartil. , vol.8 , Issue.3 , pp. 213-221
    • Westacott, C.I.1    Barakat, A.F.2    Wood, L.3
  • 29
    • 0029779371 scopus 로고    scopus 로고
    • Effects of exogenous IL-1 β, TNF α, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes
    • Henrotin YE, De Groote DD, Labasse AH et al.: Effects of exogenous IL-1 β, TNF α, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes. Osteoarthr. Cartil. 4(3), 163-173 (1996).
    • (1996) Osteoarthr. Cartil. , vol.4 , Issue.3 , pp. 163-173
    • Henrotin, Y.E.1    De Groote, D.D.2    Labasse, A.H.3
  • 30
    • 0024554594 scopus 로고
    • Arthritogenic actions of recombinant IL-1 and tumour necrosis factor α in the rabbit: Evidence for synergistic interactions between cytokines in vivo
    • Henderson B, Pettipher ER: Arthritogenic actions of recombinant IL-1 and tumour necrosis factor α in the rabbit: evidence for synergistic interactions between cytokines in vivo. Clin. Exp. Immunol. 75(2), 306-310 (1989).
    • (1989) Clin. Exp. Immunol. , vol.75 , Issue.2 , pp. 306-310
    • Henderson, B.1    Pettipher, E.R.2
  • 31
    • 0034351876 scopus 로고    scopus 로고
    • Interleukin-1β induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor-stimulated gene 6 in human osteoarthritic chondrocytes in vitro
    • DOI 10.1159/000055915
    • Stove J, Huch K, Gunther KP, Scharf HP: Interleukin-1β induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor- stimulated gene 6 in human osteoarthritic chondrocytes in vitro. Pathobiology 68(3), 144-149 (2000). (Pubitemid 32110323)
    • (2000) Pathobiology , vol.68 , Issue.3 , pp. 144-149
    • Stove, J.1    Huch, K.2    Gunther, K.-P.3    Scharf, H.-P.4
  • 32
    • 0036286667 scopus 로고    scopus 로고
    • The role of cytokines in osteoarthritis pathophysiology
    • Fernandes JC, Martel-Pelletier J, Pelletier JP: The role of cytokines in osteoarthritis pathophysiology. Biorheology, 39(1-2), 237-246 (2002).
    • (2002) Biorheology , vol.39 , Issue.1-2 , pp. 237-246
    • Fernandes, J.C.1    Martel-Pelletier, J.2    Pelletier, J.P.3
  • 33
    • 0036694645 scopus 로고    scopus 로고
    • The balance between IL-1 and IL-1RA in disease
    • In addition to this specific review on the role of IL-1 and its receptor, earlier work by Arend is very constructive in explaining mechanisms of action of IL-1
    • Arend WP: The balance between IL-1 and IL-1RA in disease. Cytokine Growth Factor Rev. 13(4-5), 323-340 (2002). ■ In addition to this specific review on the role of IL-1 and its receptor, earlier work by Arend is very constructive in explaining mechanisms of action of IL-1.
    • (2002) Cytokine Growth Factor Rev. , vol.13 , Issue.4-5 , pp. 323-340
    • Arend, W.P.1
  • 34
    • 20444409138 scopus 로고    scopus 로고
    • Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies
    • DOI 10.1016/j.jim.2005.03.009, PII S0022175905000852
    • de Jager W, Prakken BJ, Bijlsma JW, Kuis W, Rijkers GT: Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies. J. Immunol. Methods 300(1-2), 124-135 (2005). (Pubitemid 40805593)
    • (2005) Journal of Immunological Methods , vol.300 , Issue.1-2 , pp. 124-135
    • De Jager, W.1    Prakken, B.J.2    Bijlsma, J.W.J.3    Kuis, W.4    Rijkers, G.T.5
  • 35
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
    • Arend WP, Dayer JM: Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis. Arthritis Rheum. 38(2), 151-160 (1995).
    • (1995) Arthritis Rheum. , vol.38 , Issue.2 , pp. 151-160
    • Arend, W.P.1    Dayer, J.M.2
  • 36
    • 0034533367 scopus 로고    scopus 로고
    • Modulation of human chondrocyte metabolism by recombinant human interferon
    • Henrotin YE, Zheng SX, Labasse AH et al.: Modulation of human chondrocyte metabolism by recombinant human interferon. Osteoarthr. Cartil. 8(6), 474-482 (2000).
    • (2000) Osteoarthr. Cartil. , vol.8 , Issue.6 , pp. 474-482
    • Henrotin, Y.E.1    Zheng, S.X.2    Labasse, A.H.3
  • 38
    • 38349182179 scopus 로고    scopus 로고
    • Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M
    • Durigova M, Roughley PJ, Mort JS: Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M. Osteoarthr. Cartil. 16(1), 98-104 (2008).
    • (2008) Osteoarthr. Cartil. , vol.16 , Issue.1 , pp. 98-104
    • Durigova, M.1    Roughley, P.J.2    Mort, J.S.3
  • 39
    • 0036222734 scopus 로고    scopus 로고
    • The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: A time-course study using real-time quantitative reverse transcription-polymerase chain reaction
    • Koshy PJ, Lundy CJ, Rowan AD et al.: The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: a time-course study using real-time quantitative reverse transcription-polymerase chain reaction. Arthritis Rheum. 46(4), 961-967 (2002).
    • (2002) Arthritis Rheum. , vol.46 , Issue.4 , pp. 961-967
    • Koshy, P.J.1    Lundy, C.J.2    Rowan, A.D.3
  • 40
    • 40949158747 scopus 로고    scopus 로고
    • Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13
    • Long D, Blake S, Song XY, Lark M, Loeser RF: Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13. Arthritis Res. Ther. 10(1), R23 (2008).
    • (2008) Arthritis Res. Ther. , vol.10 , Issue.1
    • Long, D.1    Blake, S.2    Song, X.Y.3    Lark, M.4    Loeser, R.F.5
  • 41
    • 0141958116 scopus 로고    scopus 로고
    • IL-8/CXCl8 and growth-related oncogene α/CXCL1 induce chondrocyte hypertrophic differentiation
    • Merz D, Liu R, Johnson K, Terkeltaub R: IL-8/CXCL8 and growth-related oncogene α/CXCL1 induce chondrocyte hypertrophic differentiation. J. Immunol. 171(8), 4406-4415 (2003). (Pubitemid 37238720)
    • (2003) Journal of Immunology , vol.171 , Issue.8 , pp. 4406-4415
    • Merz, D.1    Liu, R.2    Johnson, K.3    Terkeltaub, R.4
  • 42
    • 0026660176 scopus 로고
    • Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis
    • Lotz M, Moats T, Villiger PM: Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis. J. Clin. Invest. 90(3), 888-896 (1992).
    • (1992) J. Clin. Invest. , vol.90 , Issue.3 , pp. 888-896
    • Lotz, M.1    Moats, T.2    Villiger, P.M.3
  • 43
    • 0033783333 scopus 로고    scopus 로고
    • IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage
    • Flannery CR, Little CB, Hughes CE et al.: IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage. Matrix Biol. 19(6), 549-553 (2000).
    • (2000) Matrix Biol. , vol.19 , Issue.6 , pp. 549-553
    • Flannery, C.R.1    Little, C.B.2    Hughes, C.E.3
  • 44
    • 0025695743 scopus 로고
    • Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage
    • Nietfeld JJ, Wilbrink B, Helle M et al.: Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage. Arthritis Rheum. 33(11), 1695-1701 (1990).
    • (1990) Arthritis Rheum. , vol.33 , Issue.11 , pp. 1695-1701
    • Nietfeld, J.J.1    Wilbrink, B.2    Helle, M.3
  • 45
    • 0027317928 scopus 로고
    • IL-1 β and IL-6 selectively induce transforming growth factor-β isoforms in human articular chondrocytes
    • Villiger PM, Kusari AB, ten Dijke P, Lotz M: IL-1 β and IL-6 selectively induce transforming growth factor-β isoforms in human articular chondrocytes. J. Immunol. 151(6), 3337-3344 (1993).
    • (1993) J. Immunol. , vol.151 , Issue.6 , pp. 3337-3344
    • Villiger, P.M.1    Kusari, A.B.2    Ten Dijke, P.3    Lotz, M.4
  • 46
    • 0025734094 scopus 로고
    • Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)
    • Lotz M, Guerne PA: Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA).J. Biol. Chem. 266(4), 2017-2020 (1991).
    • (1991) J. Biol. Chem. , vol.266 , Issue.4 , pp. 2017-2020
    • Lotz, M.1    Guerne, P.A.2
  • 47
    • 29144507688 scopus 로고    scopus 로고
    • Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes
    • DOI 10.1002/art.21472
    • Loeser RF, Chubinskaya S, Pacione C, Im HJ: Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes. Arthritis Rheum. 52(12), 3910-3917 (2005). (Pubitemid 41798230)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.12 , pp. 3910-3917
    • Loeser, R.F.1    Chubinskaya, S.2    Pacione, C.3    Im, H.-J.4
  • 48
    • 0037062469 scopus 로고    scopus 로고
    • Basic FGF mediates an immediate response of articular cartilage to mechanical injury
    • Vincent T, Hermansson M, Bolton M, Wait R, Saklatvala J: Basic FGF mediates an immediate response of articular cartilage to mechanical injury. Proc. Natl Acad. Sci. U.S.A. 99(12), 8259-8264 (2002).
    • (2002) Proc. Natl Acad. Sci. U.S.A. , vol.99 , Issue.12 , pp. 8259-8264
    • Vincent, T.1    Hermansson, M.2    Bolton, M.3    Wait, R.4    Saklatvala, J.5
  • 49
    • 0028326788 scopus 로고
    • Growth factor responsiveness of human articular chondrocytes: Distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts
    • Guerne PA, Sublet A, Lotz M: Growth factor responsiveness of human articular chondrocytes: distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts. J. Cell Physiol. 158(3), 476-484 (1994). (Pubitemid 24094429)
    • (1994) Journal of Cellular Physiology , vol.158 , Issue.3 , pp. 476-484
    • Guerne, P.-A.1    Sublet, A.2    Lotz, M.3
  • 50
    • 0032906440 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor α-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: Distinct targeting in the signaling pathways
    • DOI 10.1002/1529-0131(199904)42:4<710::AID-ANR14>3.0.CO;2-4
    • Alaaeddine N, Di Battista JA, Pelletier JP et al.: Inhibition of tumor necrosis factor α-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways. Arthritis Rheum. 42(4), 710-718 (1999). (Pubitemid 29171991)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.4 , pp. 710-718
    • Alaaeddine, N.1    Di Battista, J.A.2    Pelletier, J.-P.3    Kiansa, K.4    Cloutier, J.-M.5    Martel-Pelletier, J.6
  • 51
    • 0025288396 scopus 로고
    • Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist
    • Arend WP, Welgus HG, Thompson RC, Eisenberg SP: Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. J. Clin. Invest. 85(5), 1694-1697 (1990).
    • (1990) J. Clin. Invest. , vol.85 , Issue.5 , pp. 1694-1697
    • Arend, W.P.1    Welgus, H.G.2    Thompson, R.C.3    Eisenberg, S.P.4
  • 52
    • 85047697321 scopus 로고    scopus 로고
    • Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene
    • Frisbie DD, Ghivizzani SC, Robbins PD, Evans CH, McIlwraith CW: Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene. Gene Ther. 9(1), 12-20 (2002).
    • (2002) Gene Ther. , vol.9 , Issue.1 , pp. 12-20
    • Frisbie, D.D.1    Ghivizzani, S.C.2    Robbins, P.D.3    Evans, C.H.4    McIlwraith, C.W.5
  • 53
    • 0026320784 scopus 로고
    • Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor
    • Granowitz EV, Clark BD, Mancilla J, Dinarello CA: Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J. Biol. Chem. 266(22), 14147-14150 (1991).
    • (1991) J. Biol. Chem. , vol.266 , Issue.22 , pp. 14147-14150
    • Granowitz, E.V.1    Clark, B.D.2    Mancilla, J.3    Dinarello, C.A.4
  • 54
    • 0026025748 scopus 로고
    • Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1-stimulated cartilage erosion and chondrocyte responsiveness
    • Smith RJ, Chin JE, Sam LM, Justen JM: Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1-stimulated cartilage erosion and chondrocyte responsiveness. Arthritis Rheum. 34(1), 78-83 (1991).
    • (1991) Arthritis Rheum. , vol.34 , Issue.1 , pp. 78-83
    • Smith, R.J.1    Chin, J.E.2    Sam, L.M.3    Justen, J.M.4
  • 55
    • 0032429276 scopus 로고    scopus 로고
    • Rainbow trout cytokine and cytokine receptor genes
    • Secombes C, Zou J, Daniels G et al.: Rainbow trout cytokine and cytokine receptor genes. Immunol. Rev. 166, 333-340 (1998).
    • (1998) Immunol. Rev. , vol.166 , pp. 333-340
    • Secombes, C.1    Zou, J.2    Daniels, G.3
  • 56
    • 0032076751 scopus 로고    scopus 로고
    • Differential effects of IGF-1 and TGF β-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes
    • van Osch GJ, van den Berg WB, Hunziker EB, Hauselmann HJ: Differential effects of IGF-1 and TGF β-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes. Osteoarthr. Cartil. 6(3), 187-195 (1998).
    • (1998) Osteoarthr. Cartil. , vol.6 , Issue.3 , pp. 187-195
    • Van Osch, G.J.1    Van Den Berg, W.B.2    Hunziker, E.B.3    Hauselmann, H.J.4
  • 57
    • 0030947810 scopus 로고    scopus 로고
    • Transforming growth factor-β predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage
    • Lafeber FP, van Roy HL, van der Kraan PM, van den Berg WB, Bijlsma JW: Transforming growth factor-β predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage. J. Rheumatol. 24(3), 536-542 (1997).
    • (1997) J. Rheumatol. , vol.24 , Issue.3 , pp. 536-542
    • Lafeber, F.P.1    Van Roy, H.L.2    Van Der Kraan, P.M.3    Van Den Berg, W.B.4    Bijlsma, J.W.5
  • 58
    • 41149122197 scopus 로고    scopus 로고
    • Joint fluid antioxidants are decreased in osteoarthritic joints compared with joints with macroscopically intact cartilage and subacute injury
    • Regan EA, Bowler RP, Crapo JD: Joint fluid antioxidants are decreased in osteoarthritic joints compared with joints with macroscopically intact cartilage and subacute injury. Osteoarthr. Cartil. 16(4), 515-521 (2008).
    • (2008) Osteoarthr. Cartil. , vol.16 , Issue.4 , pp. 515-521
    • Regan, E.A.1    Bowler, R.P.2    Crapo, J.D.3
  • 60
    • 34250699624 scopus 로고    scopus 로고
    • Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model
    • Goodrich LR, Hidaka C, Robbins PD, Evans CH, Nixon AJ: Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model. J. Bone Joint Surg. Br. 89(5), 672-685 (2007).
    • (2007) J. Bone Joint Surg. Br. , vol.89 , Issue.5 , pp. 672-685
    • Goodrich, L.R.1    Hidaka, C.2    Robbins, P.D.3    Evans, C.H.4    Nixon, A.J.5
  • 61
    • 0036207912 scopus 로고    scopus 로고
    • Insulin-like growth factor-I enhances cell-based repair of articular cartilage
    • Fortier LA, Mohammed HO, Lust G, Nixon AJ: Insulin-like growth factor-I enhances cell-based repair of articular cartilage. J. Bone Joint Surg. Br. 84(2), 276-288 (2002).
    • (2002) J. Bone Joint Surg. Br. , vol.84 , Issue.2 , pp. 276-288
    • Fortier, L.A.1    Mohammed, H.O.2    Lust, G.3    Nixon, A.J.4
  • 62
    • 0037261211 scopus 로고    scopus 로고
    • Combined effects of insulin-like growth factor-1 and transforming growth factor-β1 on periosteal mesenchymal cells during chondrogenesis in vitro
    • Fukumoto T, Sperling JW, Sanyal A et al.: Combined effects of insulin-like growth factor-1 and transforming growth factor-β1 on periosteal mesenchymal cells during chondrogenesis in vitro. Osteoarthr. Cartil. 11(1), 55-64 (2003).
    • (2003) Osteoarthr. Cartil. , vol.11 , Issue.1 , pp. 55-64
    • Fukumoto, T.1    Sperling, J.W.2    Sanyal, A.3
  • 63
    • 0028037466 scopus 로고
    • Growth hormone directly and indirectly stimulates articular chondrocyte cell growth
    • Tsukazaki T, Matsumoto T, Enomoto H et al.: Growth hormone directly and indirectly stimulates articular chondrocyte cell growth. Osteoarthr. Cartil. 2(4), 259-267 (1994).
    • (1994) Osteoarthr. Cartil. , vol.2 , Issue.4 , pp. 259-267
    • Tsukazaki, T.1    Matsumoto, T.2    Enomoto, H.3
  • 64
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong YY, Feige U, Sarosi I et al.: Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 402(6759), 304-309 (1999).
    • (1999) Nature , vol.402 , Issue.6759 , pp. 304-309
    • Kong, Y.Y.1    Feige, U.2    Sarosi, I.3
  • 65
    • 35348875030 scopus 로고    scopus 로고
    • Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a murine model of osteoarthritis
    • DOI 10.1002/art.22941
    • Shimizu S, Asou Y, Itoh S et al.: Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a murine model of osteoarthritis. Arthritis Rheum. 56(10), 3358-3365 (2007). (Pubitemid 47585430)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.10 , pp. 3358-3365
    • Shimizu, S.1    Asou, Y.2    Itoh, S.3    Chung, U.-I.4    Kawaguchi, H.5    Shinomiya, K.6    Muneta, T.7
  • 66
    • 0035219887 scopus 로고    scopus 로고
    • Preliminary report: Relationship between osteoprotegerin/ osteoclastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee
    • DOI 10.1053/meta.2001.19327
    • Takemura M, Harada A, Mizuno M, Yano K, Yamada Y: Relationship between osteoprotegerin/osteodastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee. Metabolism 50(1), 1-2 (2001). (Pubitemid 32058540)
    • (2001) Metabolism: Clinical and Experimental , vol.50 , Issue.1 , pp. 1-2
    • Takemura, M.1    Harada, A.2    Mizuno, M.3    Yano, K.4    Yamada, Y.5
  • 67
    • 0031706086 scopus 로고    scopus 로고
    • Composition and dynamics of articular cartilage: Structure, function, and maintaining healthy state
    • Cohen NP, Foster RJ, Mow VC: Composition and dynamics of articular cartilage: structure, function, and maintaining healthy state. J. Orthop. Sports Phys. Ther. 28(4), 203-215 (1998).
    • (1998) J. Orthop. Sports Phys. Ther. , vol.28 , Issue.4 , pp. 203-215
    • Cohen, N.P.1    Foster, R.J.2    Mow, V.C.3
  • 69
    • 0033569125 scopus 로고    scopus 로고
    • Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments
    • Homandberg GA: Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments. Front Biosci. 4, D713-D730 (1999).
    • (1999) Front Biosci. , vol.4
    • Homandberg, G.A.1
  • 70
    • 0021167083 scopus 로고
    • Characterization of synovial fluid fibronectin from patients with rheumatic inflammatory diseases and healthy subjects
    • Carnemolla B, Cutolo M, Castellani P et al.: Characterization of synovial fluid fibronectin from patients with rheumatic inflammatory diseases and healthy subjects. Arthritis Rheum. 27(8), 913-921 (1984). (Pubitemid 14067787)
    • (1984) Arthritis and Rheumatism , vol.27 , Issue.8 , pp. 913-921
    • Carnemolla, B.1    Cutolo, M.2    Castellani, P.3
  • 71
    • 12844287561 scopus 로고    scopus 로고
    • Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice
    • Xu L, Peng H, Wu D et al.: Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J. Biol. Chem. 280(1), 548-555 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.1 , pp. 548-555
    • Xu, L.1    Peng, H.2    Wu, D.3
  • 72
    • 34547783916 scopus 로고    scopus 로고
    • Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis
    • DOI 10.1002/art.22761
    • Xu L, Peng H, Glasson S et al.: Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. Arthritis Rheum. 56(8), 2663-2673 (2007). (Pubitemid 47237284)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.8 , pp. 2663-2673
    • Xu, L.1    Peng, H.2    Glasson, S.3    Lee, P.L.4    Hu, K.5    Ijiri, K.6    Olsen, B.R.7    Goldring, M.B.8    Li, Y.9
  • 75
    • 0009345056 scopus 로고
    • Structure of synovial lining
    • Henderson B, Edwards JCW (Eds): Chapman and Hall Medical, Cambridge, UK
    • Henderson B, Edwards JCW (Eds): Structure of synovial lining. In: The Synovial Lining in Health and Disease. Chapman and Hall Medical, Cambridge, UK 17-40 (1987).
    • (1987) The Synovial Lining in Health and Disease , pp. 17-40
  • 76
    • 0001168336 scopus 로고
    • The origin and nature of normal human synovial fluid
    • Ropes MW, Rossmeisl EC, Bauer W: The origin and nature of normal human synovial fluid. J. Clin. Invest. 19(6), 795-799 (1940).
    • (1940) J. Clin. Invest. , vol.19 , Issue.6 , pp. 795-799
    • Ropes, M.W.1    Rossmeisl, E.C.2    Bauer, W.3
  • 77
  • 78
    • 0027588238 scopus 로고
    • Metalloprotease activity, phospholipase A2 activity and cytokine concentration in osteoarthritis synovial fluids
    • Vignon E, Balblanc JC, Mathieu P, Louisot P, Richard M: Metalloprotease activity, phospholipase A2 activity and cytokine concentration in osteoarthritis synovial fluids. Osteoarthr. Cartil. 1(2), 115-120 (1993).
    • (1993) Osteoarthr. Cartil. , vol.1 , Issue.2 , pp. 115-120
    • Vignon, E.1    Balblanc, J.C.2    Mathieu, P.3    Louisot, P.4    Richard, M.5
  • 80
    • 34547843666 scopus 로고    scopus 로고
    • Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone
    • DOI 10.1016/j.cyto.2007.06.001, PII S1043466607001512
    • Hulejova H, Baresova V, Klezl Z et al.: Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone. Cytokine 38(3), 151-156 (2007). (Pubitemid 47248299)
    • (2007) Cytokine , vol.38 , Issue.3 , pp. 151-156
    • Hulejova, H.1    Baresova, V.2    Klezl, Z.3    Polanska, M.4    Adam, M.5    Senolt, L.6
  • 81
    • 34547650510 scopus 로고    scopus 로고
    • Comparison of marker gene expression in chondrocytes from patients receiving autologous chondrocyte transplantation versus osteoarthritis patients
    • Stoop R, Albrecht D, Gaissmaier C et al.: Comparison of marker gene expression in chondrocytes from patients receiving autologous chondrocyte transplantation versus osteoarthritis patients. Arthritis Res. Ther. 9(3), R60 (2007).
    • (2007) Arthritis Res. Ther. , vol.9 , Issue.3
    • Stoop, R.1    Albrecht, D.2    Gaissmaier, C.3
  • 82
    • 0032963536 scopus 로고    scopus 로고
    • Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage
    • Moos V, Fickert S, Muller B, Weber U, Sieper J: Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage. J. Rheumatol. 26(4), 870-879 (1999). (Pubitemid 29195675)
    • (1999) Journal of Rheumatology , vol.26 , Issue.4 , pp. 870-879
    • Moos, V.1    Fickert, S.2    Muller, B.3    Weber, U.4    Sieper, J.5
  • 83
    • 0031047265 scopus 로고    scopus 로고
    • Synovial membrane inflammation and cytokine production in patients with early osteoarthritis
    • Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M: Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J. Rheumatol. 24(2), 365-371 (1997). (Pubitemid 27104104)
    • (1997) Journal of Rheumatology , vol.24 , Issue.2 , pp. 365-371
    • Smith, M.D.1    Triantafillou, S.2    Parker, A.3    Youssef, P.P.4    Coleman, M.5
  • 84
    • 0028348850 scopus 로고
    • Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies
    • Bertazzolo N, Punzi L, Stefani MP et al.: Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies. Agents Actions 41(1-2), 90-92 (1994).
    • (1994) Agents Actions , vol.41 , Issue.1-2 , pp. 90-92
    • Bertazzolo, N.1    Punzi, L.2    Stefani, M.P.3
  • 85
    • 0029739690 scopus 로고    scopus 로고
    • Practical significance of cytokine determination in joint fluid in patients with arthroses or rheumatoid arthritis
    • Neidel J, Schulze M, Sova L, Lindschau J: Practical significance of cytokine determination in joint fluid in patients with arthroses or rheumatoid arthritis. Z. Orthop. Ihre Grenzgeb. 134(4), 381-385 (1996).
    • (1996) Z. Orthop. Ihre Grenzgeb. , vol.134 , Issue.4 , pp. 381-385
    • Neidel, J.1    Schulze, M.2    Sova, L.3    Lindschau, J.4
  • 86
    • 0023677438 scopus 로고
    • Inhibition of cartilage proteoglycan synthesis by interleukin I
    • Benton HP, Tyler JA: Inhibition of cartilage proteoglycan synthesis by interleukin I. Biochem. Biophys. Res. Commun. 154(1), 421-428 (1988).
    • (1988) Biochem. Biophys. Res. Commun. , vol.154 , Issue.1 , pp. 421-428
    • Benton, H.P.1    Tyler, J.A.2
  • 88
    • 0035048597 scopus 로고    scopus 로고
    • IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis
    • DOI 10.1186/ar294
    • Chabaud M, Lubberts E, Joosten L, van Den Berg W, Miossec P. IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 3(3), 168-177 (2001). (Pubitemid 32303433)
    • (2001) Arthritis Research , vol.3 , Issue.3 , pp. 168-177
    • Chabaud, M.1    Lubberts, E.2    Joosten, L.3    Van Den Berg, W.4    Miossec, P.5
  • 89
    • 0037766040 scopus 로고    scopus 로고
    • Glucosamine and chondroitin sulfate: Biological response modifiers of chondrocytes under simulated conditions of joint stress
    • Lippiello L. Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stress. Osteoarthr. Cartil. 11(5), 335-342 (2003).
    • (2003) Osteoarthr. Cartil. , vol.11 , Issue.5 , pp. 335-342
    • Lippiello, L.1
  • 90
    • 34247880271 scopus 로고    scopus 로고
    • Resveratrol inhibits IL-1 β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro
    • Shakibaei M, John T, Seifarth C, Mobasheri A: Resveratrol inhibits IL-1 β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro. Ann. N Y. Acad. Sci. 1095, 554-563 (2007).
    • (2007) Ann. N Y. Acad. Sci. , vol.1095 , pp. 554-563
    • Shakibaei, M.1    John, T.2    Seifarth, C.3    Mobasheri, A.4
  • 91
    • 55449110376 scopus 로고    scopus 로고
    • The canine bilateral groove model of osteoarthritis
    • Interna F, DeGroot J, Elshof B et al.: The canine bilateral groove model of osteoarthritis. J. Orthop. Res. 26(11), 1471-1477 (2008).
    • (2008) J. Orthop. Res. , vol.26 , Issue.11 , pp. 1471-1477
    • Interna, F.1    DeGroot, J.2    Elshof, B.3
  • 93
    • 0015619712 scopus 로고
    • Experimentally induced degenerative joint lesions following partial meniscectomy in the rabbit
    • Moskowitz RW, Davis W, Sammarco J et al.: Experimentally induced degenerative joint lesions following partial meniscectomy in the rabbit. Arthritis Rheum. 16(3), 397-405 (1973).
    • (1973) Arthritis Rheum. , vol.16 , Issue.3 , pp. 397-405
    • Moskowitz, R.W.1    Davis, W.2    Sammarco, J.3
  • 94
    • 38949205532 scopus 로고    scopus 로고
    • Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-κBp65-specific siRNA
    • Chen LX, Lin L, Wang HJ et al.: Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-κBp65-specific siRNA. Osteoarthr. Cartil. 16(2), 174-184 (2008).
    • (2008) Osteoarthr. Cartil. , vol.16 , Issue.2 , pp. 174-184
    • Chen, L.X.1    Lin, L.2    Wang, H.J.3
  • 95
    • 0015643003 scopus 로고
    • Experimentally-induced osteoarthritis in the dog
    • Pond MJ, Nuki G. Experimentally-induced osteoarthritis in the dog. Ann. Rheum. Dis. 32(4), 387-388 (1973).
    • (1973) Ann. Rheum. Dis. , vol.32 , Issue.4 , pp. 387-388
    • Pond, M.J.1    Nuki, G.2
  • 96
    • 0032708885 scopus 로고    scopus 로고
    • The increase of parathyroid hormone-related peptide and cytokine levels in synovial fluid of elderly rheumatoid arthritis and osteoarthritis
    • Horiuchi T, Yoshida T, Koshihara Y et al.: The increase of parathyroid hormone-related peptide and cytokine levels in synovial fluid of elderly rheumatoid arthritis and osteoarthritis. Endocr.J. 46(5), 643-649 (1999).
    • (1999) Endocr.J. , vol.46 , Issue.5 , pp. 643-649
    • Horiuchi, T.1    Yoshida, T.2    Koshihara, Y.3
  • 97
    • 0029364166 scopus 로고
    • Effects of human knee synovial fluid on chondrogenesis in vitro
    • One of the earlier studies in which the role of intra-articular injury and subsequent changes in synovial fluid composition on cartilage metabolism were recognized
    • Rodrigo JJ, Steadman JR, Syftestad G, Benton H, Silliman J: Effects of human knee synovial fluid on chondrogenesis in vitro. Am. J. Knee Surg. 8(4), 124-129 (1995). ■ One of the earlier studies in which the role of intra-articular injury and subsequent changes in synovial fluid composition on cartilage metabolism were recognized.
    • (1995) Am. J. Knee Surg. , vol.8 , Issue.4 , pp. 124-129
    • Rodrigo, J.J.1    Steadman, J.R.2    Syftestad, G.3    Benton, H.4    Silliman, J.5
  • 98
    • 33744461318 scopus 로고    scopus 로고
    • Proinflammatory cytokine activities, matrix metalloproteinase-3 activity, and sulfated glycosaminoglycan content in synovial fluid of dogs with naturally acquired cranial cruciate ligament rupture
    • Fujita Y, Hara Y, Nezu Y, Schulz KS, Tagawa M: Proinflammatory cytokine activities, matrix metalloproteinase-3 activity, and sulfated glycosaminoglycan content in synovial fluid of dogs with naturally acquired cranial cruciate ligament rupture. Vet. Surg. 35(4), 369-376 (2006).
    • (2006) Vet. Surg. , vol.35 , Issue.4 , pp. 369-376
    • Fujita, Y.1    Hara, Y.2    Nezu, Y.3    Schulz, K.S.4    Tagawa, M.5
  • 99
    • 0033193125 scopus 로고    scopus 로고
    • Changes in concentrations of biochemical markers of osteoarthritis following surgical repair of ruptured cranial cruciate ligaments in dogs
    • InnesJF, Sharif M, Barr AR: Changes in concentrations of biochemical markers of osteoarthritis following surgical repair of ruptured cranial cruciate ligaments in dogs. Am. J. Vet. Res. 60(9), 1164-1168 (1999).
    • (1999) Am. J. Vet. Res. , vol.60 , Issue.9 , pp. 1164-1168
    • Innes, J.F.1    Sharif, M.2    Barr, A.R.3
  • 100
    • 34548140516 scopus 로고    scopus 로고
    • Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology
    • Ley C, Ekman S, Elmen A, Nilsson G, Eloranta ml : Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology. J. Vet. Med. A. Physiol. Pathol. Clin. Med. 54(7), 346-351 (2007).
    • (2007) J. Vet. Med. A. Physiol. Pathol. Clin. Med. , vol.54 , Issue.7 , pp. 346-351
    • Ley, C.1    Ekman, S.2    Elmen, A.3    Nilsson, G.4    Ml, E.5
  • 101
    • 0035046932 scopus 로고    scopus 로고
    • Intra-articular hyaluronic acid following knee immobilisation for 6 weeks in rabbits
    • Fu LL, Maffulli N, Chan KM: Intra-articular hyaluronic acid following knee immobilisation for 6 weeks in rabbits. Clin. Rheumatol. 20(2), 98-103 (2001).
    • (2001) Clin. Rheumatol. , vol.20 , Issue.2 , pp. 98-103
    • Fu, L.L.1    Maffulli, N.2    Chan, K.M.3
  • 102
    • 0027669992 scopus 로고
    • Repair of articular cartilage injury following intra-articular chymopapain-induced matrix proteoglycan loss
    • Williams JM, Ongchi DR, Thonar EJ: Repair of articular cartilage injury following intra-articular chymopapain-induced matrix proteoglycan loss. J. Orthop. Res. 11(5), 705-716 (1993).
    • (1993) J. Orthop. Res. , vol.11 , Issue.5 , pp. 705-716
    • Williams, J.M.1    Ongchi, D.R.2    Thonar, E.J.3
  • 103
    • 0031947430 scopus 로고    scopus 로고
    • Age- and injury-dependent concentrations of transforming growth factor-β 1 and proteoglycan fragments in rabbit knee joint fluid
    • Wei X, Messner K: Age- and injury-dependent concentrations of transforming growth factor-β 1 and proteoglycan fragments in rabbit knee joint fluid. Osteoarthr. Cartil. 6(1), 10-18 (1998).
    • (1998) Osteoarthr. Cartil. , vol.6 , Issue.1 , pp. 10-18
    • Wei, X.1    Messner, K.2
  • 104
    • 0037342667 scopus 로고    scopus 로고
    • Intraarticular inflammatory cytokines in acute anterior cruciate ligament injured knee
    • DOI 10.1016/S0968-0160(02)00083-2, PII S0968016002000832
    • Irie K, Uchiyama E, Iwaso H: Intraarticular inflammatory cytokines in acute anterior cruciate ligament injured knee. Knee 10(1), 93-96 (2003). (Pubitemid 36324521)
    • (2003) Knee , vol.10 , Issue.1 , pp. 93-96
    • Irie, K.1    Uchiyama, E.2    Iwaso, H.3
  • 105
    • 33645397152 scopus 로고    scopus 로고
    • Changes in biochemical parameters after anterior cruciate ligament injury
    • Higuchi H, Shirakura K, Kimura M et al.: Changes in biochemical parameters after anterior cruciate ligament injury. Int. Orthop. 30(1), 43-47 (2006).
    • (2006) Int. Orthop. , vol.30 , Issue.1 , pp. 43-47
    • Higuchi, H.1    Shirakura, K.2    Kimura, M.3
  • 106
    • 28444451487 scopus 로고    scopus 로고
    • Inflammatory cytokine profiles associated with chondral damage in the anterior cruciate ligament- Deficient k nee
    • Marks PH, Donaldson ml : Inflammatory cytokine profiles associated with chondral damage in the anterior cruciate ligament- deficient k nee. Arthroscopy 21(11), 1342-1347 (2005).
    • (2005) Arthroscopy , vol.21 , Issue.11 , pp. 1342-1347
    • Marks, P.H.1    Donaldson, M.L.2
  • 107
    • 33846422434 scopus 로고    scopus 로고
    • The effect of synovial fluid from injured knee joints on in vitro chondrogenesis
    • Yang KG, Saris DB, Verbout AJ, Creemers LB, Dhert WJ: The effect of synovial fluid from injured knee joints on in vitro chondrogenesis. Tissue Eng. 12(10), 2957-2964 (2006).
    • (2006) Tissue Eng. , vol.12 , Issue.10 , pp. 2957-2964
    • Yang, K.G.1    Saris, D.B.2    Verbout, A.J.3    Creemers, L.B.4    Dhert, W.J.5
  • 108
    • 3042806298 scopus 로고    scopus 로고
    • Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and ibuprofen in the treatment of osteoarthritis of the knee
    • Schiff M, Minic M: Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee. J. Rheumatol. 31(7), 1373-1383 (2004). (Pubitemid 38879205)
    • (2004) Journal of Rheumatology , vol.31 , Issue.7 , pp. 1373-1383
    • Schiff, M.1    Minic, M.2
  • 109
    • 0036319011 scopus 로고    scopus 로고
    • Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage
    • Mastbergen SC, Lafeber FP, Bijlsma JW: Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage. Rheumatology (Oxford) 41(7), 801-808 (2002).
    • (2002) Rheumatology (Oxford) , vol.41 , Issue.7 , pp. 801-808
    • Mastbergen, S.C.1    Lafeber, F.P.2    Bijlsma, J.W.3
  • 110
    • 61849096247 scopus 로고    scopus 로고
    • The chondroprorective effect of selective COX-2 inhibition in osteoarthritis: Ex vivo evaluation of human cartilage tissue after in vivo treatment
    • de Boer TN, Huisman AM, Polak AA et al.: The chondroprorective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment. Osteoarthr. Cartil. 17(4), 482-488 (2008).
    • (2008) Osteoarthr. Cartil. , vol.17 , Issue.4 , pp. 482-488
    • De Boer, T.N.1    Huisman, A.M.2    Polak, A.A.3
  • 111
    • 31044456298 scopus 로고    scopus 로고
    • Etoricoxib in the treatment of osteoarthritis over 52-weeks: A double-blind, active-comparator controlled trial [NCT00242489]
    • Curtis SP, Bockow B, Fisher C et al.: Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489]. BMC Musculoskelet. Disord. 6, 58 (2005).
    • (2005) BMC Musculoskelet. Disord. , vol.6 , pp. 58
    • Curtis, S.P.1    Bockow, B.2    Fisher, C.3
  • 112
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon SD, McMurray JJ, Pfeffer MA et al.: Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N. Engl. J. Med. 352(11), 1071-1080 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , Issue.11 , pp. 1071-1080
    • Solomon, S.D.1    Mcmurray, J.J.2    Pfeffer, M.A.3
  • 113
    • 33344461287 scopus 로고    scopus 로고
    • Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
    • Clegg DO, Reda DJ, Harris CL et al.: Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N. Engl. J. Med. 354(8), 795-808 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , Issue.8 , pp. 795-808
    • Clegg, D.O.1    Reda, D.J.2    Harris, C.L.3
  • 114
    • 17444406716 scopus 로고    scopus 로고
    • Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: Systematic review andm eta-analysis
    • Arrich J, Piribauer F, Mad P etal: Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review andm eta-analysis. CMAJ. 172(8), 1039-1043 (2005).
    • (2005) CMAJ , vol.172 , Issue.8 , pp. 1039-1043
    • Arrich, J.1    Piribauer, F.2    Mad, P.3
  • 116
    • 84925558062 scopus 로고    scopus 로고
    • Viscosupplementation for the treatment of osteoarthritis of the knee
    • CD005321
    • Bellamy N, Campbell J, Robinson V et al.: Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane Database Syst. Rev. (2), CD005321 (2006).
    • (2006) Cochrane Database Syst. Rev. , Issue.2
    • Bellamy, N.1    Campbell, J.2    Robinson, V.3
  • 117
    • 0033060229 scopus 로고    scopus 로고
    • Perceived risks of joint infection following intra-articular corticosteroid injections: A survey of rheumatologists
    • Pal B, Morris J: Perceived risks of joint infection following intra-articular corticosteroid injections: a survey of rheumatologists. Clin. Rheumatol. 18(3), 264-265 (1999).
    • (1999) Clin. Rheumatol. , vol.18 , Issue.3 , pp. 264-265
    • Pal, B.1    Morris, J.2
  • 118
    • 34447299665 scopus 로고    scopus 로고
    • Preliminary effects of hyaluronic acid on early rehabilitation of patients with isolated anterior cruciate ligament reconstruction
    • Huang MH, Yang RC, Chou PH: Preliminary effects of hyaluronic acid on early rehabilitation of patients with isolated anterior cruciate ligament reconstruction. Clin. J. Sport Med. 17(4), 242-250 (2007).
    • (2007) Clin. J. Sport Med. , vol.17 , Issue.4 , pp. 242-250
    • Huang, M.H.1    Yang, R.C.2    Chou, P.H.3
  • 119
    • 41249087458 scopus 로고    scopus 로고
    • Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared with placebo in a prospective randomized controlled trial
    • Yang KG, Raijmakers NJ, van Arkel ER et al.: Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared with placebo in a prospective randomized controlled trial. Osteoarthr. Cartil. 16(4), 498-505 (2008).
    • (2008) Osteoarthr. Cartil. , vol.16 , Issue.4 , pp. 498-505
    • Yang, K.G.1    Raijmakers, N.J.2    Van Arkel, E.R.3
  • 120
    • 77953448351 scopus 로고    scopus 로고
    • Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis
    • Baltzer AW, Moser C, Jansen SA, Krauspe R: Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis. Osteoarthr. Cartil. (2008).
    • (2008) Osteoarthr. Cartil.
    • Baltzer, A.W.1    Moser, C.2    Jansen, S.A.3    Krauspe, R.4
  • 121
    • 33645719123 scopus 로고    scopus 로고
    • Results from a double blind, placebo-controlled, multicenter trial of a single intra-articular injection of anakinra (Kineret®) in patients with osteoarthritis of the knee
    • Chevalier X, Goupille P, Beaulieu AD et al.: Results from a double blind, placebo-controlled, multicenter trial of a single intra-articular injection of anakinra (Kineret®) in patients with osteoarthritis of the knee. Arthritis Rheum. 52(9), S507-S507 (2005).
    • (2005) Arthritis Rheum. , vol.52 , Issue.9
    • Chevalier, X.1    Goupille, P.2    Beaulieu, A.D.3
  • 122
    • 0030961873 scopus 로고    scopus 로고
    • In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy
    • Pelletier JP, Caron JP, Evans C et al.: In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum. 40(6), 1012-1019 (1997).
    • (1997) Arthritis Rheum. , vol.40 , Issue.6 , pp. 1012-1019
    • Pelletier, J.P.1    Caron, J.P.2    Evans, C.3
  • 123
    • 0141956375 scopus 로고    scopus 로고
    • The production of anti-inflammatory cytokines in whole blood by physico-chemical induction
    • Meijer H, Reinecke J, Becker C, Tholen G, Wehling P: The production of anti-inflammatory cytokines in whole blood by physico-chemical induction. Inflamm. Res. 52(10), 404-407 (2003).
    • (2003) Inflamm. Res. , vol.52 , Issue.10 , pp. 404-407
    • Meijer, H.1    Reinecke, J.2    Becker, C.3    Tholen, G.4    Wehling, P.5
  • 124
    • 33947652733 scopus 로고    scopus 로고
    • Clinical, biochemical, and histologic effects of intra-articular administration of autologous conditioned serum in horses with experimentally induced osteoarthritis
    • Frisbie DD, Kawcak CE, Werpy NM, Park RD, McIlwraith CW: Clinical, biochemical, and histologic effects of intra-articular administration of autologous conditioned serum in horses with experimentally induced osteoarthritis. Am. J Vet. Res. 68(3), 290-296 (2007).
    • (2007) Am. J Vet. Res. , vol.68 , Issue.3 , pp. 290-296
    • Frisbie, D.D.1    Kawcak, C.E.2    Werpy, N.M.3    Park, R.D.4    McIlwraith, C.W.5
  • 125
    • 41249087458 scopus 로고    scopus 로고
    • Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared with placebo in a prospective randomized controlled trial
    • Yang KG, Raijmakers NJ, van Arkel ER et al.: Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared with placebo in a prospective randomized controlled trial. Osteoarthr. Cartil. 16(4), 498-505 (2008).
    • (2008) Osteoarthr. Cartil. , vol.16 , Issue.4 , pp. 498-505
    • Yang, K.G.1    Raijmakers, N.J.2    Van Arkel, E.R.3
  • 126
    • 56049109217 scopus 로고    scopus 로고
    • The placebo effect and its determinants in osteoarthritis - Meta-analysis of randomised controlled trials
    • Zhang W, Robertson J, Jones AC, Dieppe PA, Doherty M: The placebo effect and its determinants in osteoarthritis - meta-analysis of randomised controlled trials. Ann. Rheum. Dis. 67(12), 1716-1723 (2008).
    • (2008) Ann. Rheum. Dis. , vol.67 , Issue.12 , pp. 1716-1723
    • Zhang, W.1    Robertson, J.2    Jones, A.C.3    Dieppe, P.A.4    Doherty, M.5
  • 127
    • 58149250232 scopus 로고    scopus 로고
    • Assessment of the efficacy of joint lavage in rabbits with osteoarthritis of the knee
    • Fu X, Lin L, Zhang J, Yu C: Assessment of the efficacy of joint lavage in rabbits with osteoarthritis of the knee. J. Orthop. Res. 27(1), 91-96 (2009).
    • (2009) J. Orthop. Res. , vol.27 , Issue.1 , pp. 91-96
    • Fu, X.1    Lin, L.2    Zhang, J.3    Yu, C.4
  • 128
    • 49049087511 scopus 로고    scopus 로고
    • A high interleukin 1 receptor antagonist/IL-1β ratio occurs naturally in knee osteoarthritis
    • Richette P, Francois M, Vicaut E et al.: A high interleukin 1 receptor antagonist/IL-1β ratio occurs naturally in knee osteoarthritis. J. Rheumatol. 35(8), 1650-1654 (2008).
    • (2008) J. Rheumatol. , vol.35 , Issue.8 , pp. 1650-1654
    • Richette, P.1    Francois, M.2    Vicaut, E.3
  • 129
    • 34948826557 scopus 로고    scopus 로고
    • Autologous conditioned serum in the treatment of orthopedic diseases: The Orthokine therapy
    • DOI 10.2165/00063030-200721050-00004
    • Wehling P, Moser C, Frisbie D et al.: Autologous conditioned serum in the treatment of orthopedic diseases: the orthokine therapy. BioDrugs 21(5), 323-332 (2007). (Pubitemid 47529471)
    • (2007) BioDrugs , vol.21 , Issue.5 , pp. 323-332
    • Wehling, P.1    Moser, C.2    Frisbied, D.3    McIlwraith, C.W.4    Kawcak, C.E.5    Krauspe, R.6    Reinecke, J.A.7
  • 131
    • 33645131117 scopus 로고    scopus 로고
    • Successful treatment of inflammatory knee osteoarthritis with tumour necrosis factor blockade
    • Grunke M, Schulze-Koops H: Successful treatment of inflammatory knee osteoarthritis with tumour necrosis factor blockade. Ann. Rheum. Dis. 65(4), 555-556 (2006).
    • (2006) Ann. Rheum. Dis. , vol.65 , Issue.4 , pp. 555-556
    • Grunke, M.1    Schulze-Koops, H.2
  • 132
    • 0037061888 scopus 로고    scopus 로고
    • Cytokines induce inflammation and cartilage degradation. Oral TNF-α blocker against arthrosis
    • Cytokines induce inflammation and cartilage degradation. Oral TNF-α blocker against arthrosis. MMW Fortschr. Med. 144(15), 64 (2002).
    • (2002) MMW Fortschr. Med. , vol.144 , Issue.15 , pp. 64
  • 133
    • 17444448249 scopus 로고    scopus 로고
    • Osteoarthritic synovial fluid and synovium supernatants up-regulate tumor necrosis factor receptors on human articular chondrocytes
    • Webb GR, Westacott CI,Elson CJ: Osteoarthritic synovial fluid and synovium supernatants up-regulate tumor necrosis factor receptors on human articular chondrocytes. Osteoarthr. Cartil. 6(3), 167-176 (1998).
    • (1998) Osteoarthr. Cartil. , vol.6 , Issue.3 , pp. 167-176
    • Webb, G.R.1    Westacott, C.I.2    Elson, C.J.3
  • 134
    • 0036012888 scopus 로고    scopus 로고
    • Effects of TNFα-antagonists on nitric oxide production in human cartilage
    • Vuolteenaho K, Moilanen T, Hamalainen M, Moilanen E: Effects of TNFα-antagonists on nitric oxide production in human cartilage. Osteoarthr. Cartil. 10(4), 327-332 (2002).
    • (2002) Osteoarthr. Cartil. , vol.10 , Issue.4 , pp. 327-332
    • Vuolteenaho, K.1    Moilanen, T.2    Hamalainen, M.3    Moilanen, E.4
  • 135
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • DOI 10.1001/jama.295.19.2275
    • Bongartz T, Sutton AJ, Sweeting MJ et al.: Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 295(19), 2275-2285 (2006). (Pubitemid 43736578)
    • (2006) Journal of the American Medical Association , vol.295 , Issue.19 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3    Buchan, I.4    Matteson, E.L.5    Montori, V.6
  • 136
    • 0035163230 scopus 로고    scopus 로고
    • Protocol issues for delayed Gd(DTPA) (2-)-enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage
    • Clear explanation of a promising and currently broadly recognized technique for the noninvasive imaging of cartilage by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC)
    • Burstein D, Velyvis J, Scott KT et al.: Protocol issues for delayed Gd(DTPA) (2-)-enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage. Magn. Reson. Med. 45(1), 36-41 (2001). ■ Clear explanation of a promising and currently broadly recognized technique for the noninvasive imaging of cartilage by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC).
    • (2001) Magn. Reson. Med. , vol.45 , Issue.1 , pp. 36-41
    • Burstein, D.1    Velyvis, J.2    Scott, K.T.3
  • 137
    • 28544443402 scopus 로고    scopus 로고
    • Glycosaminoglycan content of knee cartilage following posterior cruciate ligament rupture demonstrated by delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC). A case report
    • Young AA, Stanwell P, Williams A et al.: Glycosaminoglycan content of knee cartilage following posterior cruciate ligament rupture demonstrated by delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC). A case report. J. Bone Joint Surg. Am. 87(12), 2763-2767 (2005).
    • (2005) J. Bone Joint Surg. Am. , vol.87 , Issue.12 , pp. 2763-2767
    • Young, A.A.1    Stanwell, P.2    Williams, A.3
  • 138
    • 0031596527 scopus 로고    scopus 로고
    • The effect of Y-25510 injection on the serum levels of some cytokines in healthy adult volunteers
    • Azuma J, Ogura M, Yamamoto I et al.: The effect of Y-25510 injection on the serum levels of some cytokines in healthy adult volunteers. Eur. J. Clin. Pharmacol. 53(6), 411-419 (1998).
    • (1998) Eur. J. Clin. Pharmacol. , vol.53 , Issue.6 , pp. 411-419
    • Azuma, J.1    Ogura, M.2    Yamamoto, I.3
  • 139
    • 0031694535 scopus 로고    scopus 로고
    • Study of pro-inflammatory (TNF-α, IL-1α, IL-6) and T-cell-derived (IL-2, IL-4) cytokines in plasma and synovial fluid of patients with juvenile chronic arthritis: Correlations with clinical and laboratory parameters
    • Kutukculer N, Caglayan S, Aydogdu F: Study of pro-inflammatory (TNF-α, IL-1α, IL-6) and T-cell-derived (IL-2, IL-4) cytokines in plasma and synovial fluid of patients with juvenile chronic arthritis: correlations with clinical and laboratory parameters. Clin. Rheumatol. 17(4), 288-292 (1998).
    • (1998) Clin. Rheumatol. , vol.17 , Issue.4 , pp. 288-292
    • Kutukculer, N.1    Caglayan, S.2    Aydogdu, F.3
  • 140
    • 31544468755 scopus 로고    scopus 로고
    • Mirthful laughter differentially affects serum pro- And anti-inflammatory cytokine levels depending on the level of disease activity in patients with rheumatoid arthritis
    • DOI 10.1093/rheumatology/kei081
    • Matsuzaki T, Nakajima A, Ishigami S, Tanno M, Yoshino S: Mirthful laughter differentially affects serum pro- and anti-inflammatory cytokine levels depending on the level of disease activity in patients with rheumatoid arthritis. Rheumatology (Oxford) 45(2), 182-186 (2006). (Pubitemid 43160080)
    • (2006) Rheumatology , vol.45 , Issue.2 , pp. 182-186
    • Matsuzaki, T.1    Nakajima, A.2    Ishigami, S.3    Tanno, M.4    Yoshino, S.5
  • 141
    • 0033501137 scopus 로고    scopus 로고
    • Serum levels of IL-6 type cytokines and soluble IL-6 receptors in active B-cell chronic lymphocytic leukemia and in cladribine induced remission
    • Robak T, Wierzbowska A, Blasinska-Morawiec M, Korycka A, Blonski JZ: Serum levels of IL-6 type cytokines and soluble IL-6 receptors in active B-cell chronic lymphocytic leukemia and in cladribine induced remission. Mediators Inflamm. 8(6), 277-286 (1999). (Pubitemid 30232873)
    • (1999) Mediators of Inflammation , vol.8 , Issue.6 , pp. 277-286
    • Robak, T.1    Wierzbowska, A.2    Blasinska-Morawiec, M.3    Korycka, A.4    Blonski, J.Z.5
  • 142
    • 0034783163 scopus 로고    scopus 로고
    • Variations in serum IL-7 and 90K/Mac-2 binding protein (Mac-2 BP) levels analysed in cohorts of HIV-1 patients and correlated with clinical changes following antiretroviral therapy
    • Darcissac EC, Vidal V, De La Tribonniere X, Mouton Y, Bahr GM: Variations in serum IL-7 and 90K/Mac-2 binding protein (Mac-2 BP) levels analysed in cohorts of HIV-1 patients and correlated with clinical changes following antiretroviral therapy. Clin. Exp. Immunol. 126(2), 287-294 (2001).
    • (2001) Clin. Exp. Immunol. , vol.126 , Issue.2 , pp. 287-294
    • Darcissac, E.C.1    Vidal, V.2    De La Tribonniere, X.3    Mouton, Y.4    Bahr, G.M.5
  • 144
    • 33745713597 scopus 로고    scopus 로고
    • Blood serum levels of IL-2, IL-6,IL-8, TNF-α and IL-1β in patients on maintenance hemodialysis
    • Rysz J, Banach M, Cialkowska-Rysz A et al.: Blood serum levels of IL-2, IL-6,IL-8, TNF-α and IL-1β in patients on maintenance hemodialysis. Cell Mol. Immunol. 3(2), 151-154 (2006).
    • (2006) Cell Mol. Immunol. , vol.3 , Issue.2 , pp. 151-154
    • Rysz, J.1    Banach, M.2    Cialkowska-Rysz, A.3
  • 145
    • 0035178667 scopus 로고    scopus 로고
    • Serum levels of interleukins (IL)-4, IL-5, IL-13, and interferon-γ in acute asthma
    • Lee YC, Lee KH, Lee HB, Rhee YK: Serum levels of interleukins (IL)-4, IL-5, IL-13, and interferon-γ in acute asthma. J. Asthma 38(8), 665-671 (2001).
    • (2001) J. Asthma , vol.38 , Issue.8 , pp. 665-671
    • Lee, Y.C.1    Lee, K.H.2    Lee, H.B.3    Rhee, Y.K.4
  • 146
    • 33644809273 scopus 로고    scopus 로고
    • Serum interleukin 17 and interleukin 18 levels in familial Mediterranean fever
    • Haznedaroglu S, Ozturk MA, Sancak B et al.: Serum interleukin 17 and interleukin 18 levels in familial Mediterranean fever. Clin. Exp. Rheumatol. 23(4 Suppl 38), S77-80 (2005).
    • (2005) Clin. Exp. Rheumatol. , vol.23 , Issue.4 SUPPL. 38
    • Haznedaroglu, S.1    Ozturk, M.A.2    Sancak, B.3
  • 147
    • 40649083317 scopus 로고    scopus 로고
    • Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases
    • Agarwal S, Misra R, Aggarwal A: Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases. J. Rheumatol. 35(3), 515-519 (2008).
    • (2008) J. Rheumatol. , vol.35 , Issue.3 , pp. 515-519
    • Agarwal, S.1    Misra, R.2    Aggarwal, A.3
  • 149
    • 0034040139 scopus 로고    scopus 로고
    • Synovial fluid levels of tumor necrosis factor α and oncostatin M correlate with levels of markers of the degradation of crosslinked collagen and cartilage aggrecan in rheumatoid arthritis but not in osteoarthritis
    • DOI 10.1002/1529-0131(200002)43:2<281::AID-ANR7>3.0.CO;2-7
    • Manicourt DH, Poilvache P, Van Egeren A et al.: Synovial fluid levels of tumor necrosis factor α and oncostatin M correlate with levels of markers of the degradation of crosslinked collagen and cartilage aggrecan in rheumatoid arthritis but not in osteoarthritis. Arthritis Rheum. 43(2), 281-288 (2000). (Pubitemid 30395736)
    • (2000) Arthritis and Rheumatism , vol.43 , Issue.2 , pp. 281-288
    • Manicourt, D.-H.1    Poilvache, P.2    Van Egeren, A.3    Devogelaer, J.-P.4    Lenz, M.-E.5    Thonar, E.J.-M.A.6
  • 150
    • 0030903094 scopus 로고    scopus 로고
    • The synovial expression and serum levels of interleukin-6, interleukin- 11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis
    • DOI 10.1002/art.1780400614
    • Okamoto H, Yamamura M, Morita Y et al.: The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis. Arthritis Rheum. 40(6), 1096-1105 (1997). (Pubitemid 27242297)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.6 , pp. 1096-1105
    • Okamoto, H.1    Yamamura, M.2    Morita, Y.3    Harada, S.4    Makino, H.5    Ota, Z.6
  • 151
    • 33746040154 scopus 로고    scopus 로고
    • The serum levels of growth factors: PDGF, TGF-β and VEGF are increased after strenuous physical exercise
    • Czarkowska-Paczek B, Bartlomiejczyk I, Przybylski J: The serum levels of growth factors: PDGF, TGF-β and VEGF are increased after strenuous physical exercise. J. Physiol. Pharmacol. 57(2), 189-197 (2006).
    • (2006) J. Physiol. Pharmacol. , vol.57 , Issue.2 , pp. 189-197
    • Czarkowska-Paczek, B.1    Bartlomiejczyk, I.2    Przybylski, J.3
  • 152
    • 70349345810 scopus 로고    scopus 로고
    • Serum IGF-I and C-reactive protein in healthy black and white young men: The CARDIA male hormone study
    • Colangelo LA, Chiu B, Kopp P, Liu K, Gapstur SM: Serum IGF-I and C-reactive protein in healthy black and white young men: The CARDIA male hormone study. Growth Horm. IGF Res. (2009).
    • (2009) Growth Horm. IGF Res.
    • Colangelo, L.A.1    Chiu, B.2    Kopp, P.3    Liu, K.4    Gapstur, S.M.5
  • 153
    • 0029907076 scopus 로고    scopus 로고
    • IGF and IGF-binding protein system in the synovial fluid of osteoarthritic and rheumatoid arthritic patients
    • Tavera C, Abribat T, Reboul P et al.: IGF and IGF-binding protein system in the synovial fluid of osteoarthritic and rheumatoid arthritic patients.
    • (1996) Osteoarthr. Cartil. , vol.4 , Issue.4 , pp. 263-274
    • Tavera, C.1    Abribat, T.2    Reboul, P.3


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