-
1
-
-
0026698778
-
Enhancement of host defense by Y-25510, ( ±)-3-[4-(2-dimethylamino-1-methylethoxy) phenyl]-1H-pyrazolo-[3,4-b]pyridine-1-acetic acid, a novel synthetic compound. A comparison with recombinant human granulocyte colony-stimulating factor in 5-fluorouracil-treated mice
-
Hisadome M, Fukuda T, Terasawa M, Oe T, Takahata H, Goto K, Turuta S, Nomoto K (1992) Enhancement of host defense by Y-25510, ( ±)-3-[4-(2-dimethylamino-1-methylethoxy) phenyl]-1H-pyrazolo-[3,4-b]pyridine-1-acetic acid, a novel synthetic compound. A comparison with recombinant human granulocyte colony-stimulating factor in 5-fluorouracil-treated mice. Int J Immunopharmacol 14: 1195-1201
-
(1992)
Int J Immunopharmacol
, vol.14
, pp. 1195-1201
-
-
Hisadome, M.1
Fukuda, T.2
Terasawa, M.3
Oe, T.4
Takahata, H.5
Goto, K.6
Turuta, S.7
Nomoto, K.8
-
2
-
-
0024322829
-
Interleukin-1 potentiates granulopoiesis and thrombopoiesis by producing hematopoietic factors in vivo
-
Nakai S, Aihara K, Hirai Y (1989) Interleukin-1 potentiates granulopoiesis and thrombopoiesis by producing hematopoietic factors in vivo. Life Sci 45: 585-591
-
(1989)
Life Sci
, vol.45
, pp. 585-591
-
-
Nakai, S.1
Aihara, K.2
Hirai, Y.3
-
3
-
-
0024446495
-
Interleukin 6 is a potent thrombopoietic factor in vivo in mice
-
Ishibashi T, Kimura H, Shikama Y, Uchida T, Kariyone S, Hirano T (1989) Interleukin 6 is a potent thrombopoietic factor in vivo in mice. Blood 74: 1241-1244
-
(1989)
Blood
, vol.74
, pp. 1241-1244
-
-
Ishibashi, T.1
Kimura, H.2
Shikama, Y.3
Uchida, T.4
Kariyone, S.5
Hirano, T.6
-
4
-
-
0025218965
-
In vivo effects of recombinant human interleukin-6 in primates: Stimulated production of platelets
-
Asano S, Okano A, Ozuwa K, Nakahata T, Ishibashi T, Koike K, Kimura H, Tanioka Y, Shibuya A, Hirano T, Kishimato T, Takaku F, Akiyama Y (1990) In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets. Blood 75: 1602-1605
-
(1990)
Blood
, vol.75
, pp. 1602-1605
-
-
Asano, S.1
Okano, A.2
Ozuwa, K.3
Nakahata, T.4
Ishibashi, T.5
Koike, K.6
Kimura, H.7
Tanioka, Y.8
Shibuya, A.9
Hirano, T.10
Kishimato, T.11
Takaku, F.12
Akiyama, Y.13
-
5
-
-
0030158059
-
Enhancement of in vivo production of IL-1α and IL-6 in mice by Y-25510, a 1H-pyrazolo-[3,4-b]pyridine-1-acetic acid derivative
-
Hisadome M, Fukuda T, Matsuyuki H, Ikeda Y, Nomoto K (1996) Enhancement of in vivo production of IL-1α and IL-6 in mice by Y-25510, a 1H-pyrazolo-[3,4-b]pyridine-1-acetic acid derivative. Int J Immunopharmacol 18: 379-384
-
(1996)
Int J Immunopharmacol
, vol.18
, pp. 379-384
-
-
Hisadome, M.1
Fukuda, T.2
Matsuyuki, H.3
Ikeda, Y.4
Nomoto, K.5
-
6
-
-
0030299075
-
( ± )-3-[4-(2-dimethylamino-1-methylethoxy)phenyl]-1H-pyrazolo [3, 4-b]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1β and IL-6 at the level of messenger RNA expression in cultured human monocytes
-
1996
-
Kusuhara H, Komatsu H, Hisadome M, Ikeda Y (1997) ( ± )-3-[4-(2-dimethylamino-1-methylethoxy)phenyl]-1H-pyrazolo [3, 4-b]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1β and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol 18: 719-728 (1996)
-
(1997)
Int J Immunopharmacol
, vol.18
, pp. 719-728
-
-
Kusuhara, H.1
Komatsu, H.2
Hisadome, M.3
Ikeda, Y.4
-
7
-
-
6844253024
-
A clinical phase study of IL-1
-
Kitamura K, Takaku F (1989) A clinical phase study of IL-1 (abstract). Biotherapy 3: 1430-1437
-
(1989)
Biotherapy
, vol.3
, pp. 1430-1437
-
-
Kitamura, K.1
Takaku, F.2
-
8
-
-
0026633556
-
The toxic and hematologic effects of interleukin-1 alpha administrated in a phase I trial to patients with advanced malignancies
-
Smith II JW, Urba WJ, Curti BD, Elwood LJ, Steis RG, Janik JE (1992) The toxic and hematologic effects of interleukin-1 alpha administrated in a phase I trial to patients with advanced malignancies. J Clin Oncol 10: 1141-1152
-
(1992)
J Clin Oncol
, vol.10
, pp. 1141-1152
-
-
Smith II, J.W.1
Urba, W.J.2
Curti, B.D.3
Elwood, L.J.4
Steis, R.G.5
Janik, J.E.6
-
9
-
-
0005497545
-
Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: Safety and pharmacokinetics in single subcutaneous administration
-
in Japanese with English abstract
-
Azuma J, Kurimoto T, Awata S, Sawamura A, Yoshida H, Seto Y (1989) Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: safety and pharmacokinetics in single subcutaneous administration (in Japanese with English abstract). Rinsyo Iyaku 5: 2231-2252
-
(1989)
Rinsyo Iyaku
, vol.5
, pp. 2231-2252
-
-
Azuma, J.1
Kurimoto, T.2
Awata, S.3
Sawamura, A.4
Yoshida, H.5
Seto, Y.6
-
10
-
-
0342522757
-
Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: Safety and pharmacokinetics in single intravenous infusion
-
in Japanese with English abstract
-
Azuma J, Hamaguchi T, Seung-Eun P, Kurimoto T, Yoshida H, Seto Y, Mochizuki N, Kaneko T, Shimosaka A, Itoh H, Akahori H, Takaku F (1989) Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: safety and pharmacokinetics in single intravenous infusion (in Japanese with English abstract). Rinsyo Iyaku 5: 1579-1603
-
(1989)
Rinsyo Iyaku
, vol.5
, pp. 1579-1603
-
-
Azuma, J.1
Hamaguchi, T.2
Seung-Eun, P.3
Kurimoto, T.4
Yoshida, H.5
Seto, Y.6
Mochizuki, N.7
Kaneko, T.8
Shimosaka, A.9
Itoh, H.10
Akahori, H.11
Takaku, F.12
-
11
-
-
0343828049
-
Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: Safety and pharmacokinetics in consecutive subcutaneous administration
-
in Japanese with English abstract
-
Azuma J, Tsuji S, Seung-Eun P, Yoshida H, Seto Y, Mochizuki N, Kaneko T, Shimosaka A, Itoh H, Akahori H, Mikawa K, Sasahara K, Takaku F (1989) Phase I study of KRN 8601 (rhG-CSF) in normal healthy volunteers: safety and pharmacokinetics in consecutive subcutaneous administration (in Japanese with English abstract). Rinsyo Iyaku 5: 2253-2269
-
(1989)
Rinsyo Iyaku
, vol.5
, pp. 2253-2269
-
-
Azuma, J.1
Tsuji, S.2
Seung-Eun, P.3
Yoshida, H.4
Seto, Y.5
Mochizuki, N.6
Kaneko, T.7
Shimosaka, A.8
Itoh, H.9
Akahori, H.10
Mikawa, K.11
Sasahara, K.12
Takaku, F.13
-
12
-
-
0026094306
-
Interleukin 10 (IL-10) inhibits cytokine synthesis byhuman monocytes: An autoreguratory role of IL-10 produced by monocytes
-
Malefyt RDW, Abrams J, Bennett B, Figdor CG, Vries JED (1991) Interleukin 10 (IL-10) inhibits cytokine synthesis byhuman monocytes: an autoreguratory role of IL-10 produced by monocytes. J Exp Med 174: 1209-1220
-
(1991)
J Exp Med
, vol.174
, pp. 1209-1220
-
-
Malefyt, R.D.W.1
Abrams, J.2
Bennett, B.3
Figdor, C.G.4
Vries, J.E.D.5
-
13
-
-
0025889028
-
IL-10 inhibits cytokine production by activated macrophages
-
Fiorentino DF, Zlotnik A, Mosman TR, Howard M, O'garra A (1991) IL-10 inhibits cytokine production by activated macrophages. J Immunol 147: 3815-3822
-
(1991)
J Immunol
, vol.147
, pp. 3815-3822
-
-
Fiorentino, D.F.1
Zlotnik, A.2
Mosman, T.R.3
Howard, M.4
O'garra, A.5
|