Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies

Journal of Immunological Methods

Volumn 300, Issue 1-2, 2005, Pages 124-135

  De Jager, Wilco ^a,c,d   Prakken, Berent J ^a,c,d   Bijlsma, Johannes W J ^b   Kuis, Wietse ^a,c,d   Rijkers, Ger T ^a,b,c,d  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c IACOPO Institute for Translational Medicine   (Netherlands)

^d IACOPO Institute for Translational Medicine   (United States)

Author keywords

Cytokines; Luminex; Multiplex immunoassay; Protein L; Rheumatoid factor

Indexed keywords

AUTOANTIBODY; HETEROPHILE ANTIBODY; IMMUNOGLOBULIN; MACROGOL; PROTEIN; RHEUMATOID FACTOR;

ABSORPTION; ADULT; AGED; ANTIBODY DETECTION; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOASSAY; INTERMETHOD COMPARISON; MALE; MULTIPLEX IMMUNOASSAY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; STATISTICAL SIGNIFICANCE; SYNOVIAL FLUID; VALIDATION PROCESS; VARIANCE;

ANTIBODIES, HETEROPHILE; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; BLOOD PROTEINS; CASE-CONTROL STUDIES; CHEMOKINES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOASSAY; OSTEOARTHRITIS; SYNOVIAL FLUID;

RODENTIA;

EID: 20444409138     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2005.03.009     Document Type: Article

References (22)

1. B. Akerstrom, and L. Bjorck Protein L: an immunoglobulin light chain-binding bacterial protein. Characterization of binding and physicochemical properties J. Biol. Chem. 1989 19740
2. A. Davidson, and B. Diamond Autoimmune diseases N. Engl. J. Med. 2001 340
3. W. de Jager, H. Te Velthuis, B.J. Prakken, W. Kuis, and G.T. Rijkers Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells Clin. Diagn. Lab. Immunol. 2003 133
4. L. De Rycke, E. Kruithof, N. Van Damme, I.E. Hoffman, B.N. Van den, B.F. Van den, E.M. Veys, and F. De Keyser Antinuclear antibodies following infliximab treatment in patients with rheumatoid arthritis or spondylarthropathy Arthritis Rheum. 2003 1015
5. M.J. Elliott, R.N. Maini, M. Feldmann, A. Long-Fox, P. Charles, H. Bijl, and J.N. Woody Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis Lancet 1994 1125
6. R.M. Fleishmann Safety of anakinra, a recombinant interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis and comparison to anti-TNF-alpha agents Clin. Exp. Rheumatol. 2002 S35
7. N. Godessart, and S.L. Kunkel Chemokines in autoimmune disease Curr. Opin. Immunol. 2001 670
8. C. Hennig, L. Rink, U. Fagin, W.J. Jabs, and H. Kirchner The influence of naturally occurring heterophilic anti-immunoglobulin antibodies on direct measurement of serum proteins using sandwich ELISAs J. Immunol. Methods 2000 71
9. K.L. Kellar, R.R. Kalwar, K.A. Dubois, D. Crouse, W.D. Chafin, and B.E. Kane Multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants Cytometry 2001 27
10. S.S. Khan, M.S. Smith, D. Reda, A.F. Suffredini, and J.P. McCoy Jr. Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers Cytometry 2004 35
11. L.J. Kricka Human anti-animal antibody interferences in immunological assays Clin. Chem. 1999 942
12. A.D. Luster Chemokines-chemotactic cytokines that mediate inflammation N. Engl. J. Med. 1998 436
13. S.A. Luther, and J.G. Cyster Chemokines as regulators of T cell differentiation Nat. Immunol. 2001 102
14. T.B. Martins, B.M. Pasi, C.M. Litwin, and H.R. Hill Heterophile antibody interference in a multiplexed fluorescent microsphere immunoassay for quantitation of cytokines in human serum Clin. Diagn. Lab. 2004 325
15. T.L. Moore, R.W. Dorner, and J. Zuckner 19S IgM rheumatoid factor-7S IgG rheumatoid factor immune complexes isolated in patients with rheumatoid arthritis J. Lab. Clin. Med. 1986 465
16. A. O'Garra, and K. Murphy Role of cytokines in determining T-lymphocyte function Nat. Rev., Immunol. 1994 458
17. J.J. O'Shea, A. Ma, and P. Lipsky Cytokines and autoimmunity Nat. Rev., Immunol. 2002 37
18. U. Prabhakar, E. Eirikis, and H.M. Davis Simultaneous quantification of proinflammatory cytokines in human plasma using the LabMAP assay J. Immunol. Methods 2002 207
19. U. Prabhakar, E. Eirikis, M. Reddy, E. Silvestro, S. Spitz, C. Pendley, H.M. Davis, and B.E. Miller Validation and comparative analysis of a multiplexed assay for the simultaneous quantitative measurement of Th1/Th2 cytokines in human serum and human peripheral blood mononuclear cell culture supernatants J. Immunol. Methods 2004 27
20. M. Tiittanen, M. Knip, and O. Vaarala Anti-insulin activity in IgG-fractions from children with newly-diagnosed type 1 diabetes and negative for insulin autoantibodies Autoimmunity 2004 45
21. D.A. Vignali Multiplexed particle-based flow cytometric assays J. Immunol. Methods 2000 243
22. M. Ziolkowska, A. Koc, G. Luszczykiewicz, K. Ksiezopolska-Pietrzak, E. Klimczak, H. Chwalinska-Sadowska, and W. Maslinski High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism J. Immunol. 2000 2832