메뉴 건너뛰기




Volumn , Issue , 2009, Pages 425-442

Pathophysiology of copd

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77953094454     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374001-4.00034-1     Document Type: Chapter
Times cited : (7)

References (102)
  • 2
    • 34548222188 scopus 로고    scopus 로고
    • Global burden of COPD: Risk factors, prevalence, and future trends
    • Mannino D.M., Buist A.S. Global burden of COPD: Risk factors, prevalence, and future trends. Lancet 2007, 370:765-773.
    • (2007) Lancet , vol.370 , pp. 765-773
    • Mannino, D.M.1    Buist, A.S.2
  • 3
    • 33751236493 scopus 로고    scopus 로고
    • Developing COPD: A 25 year follow up study of the general population
    • Lokke A., Lange P., Scharling H., Fabricius P., Vestbo J. Developing COPD: A 25 year follow up study of the general population. Thorax 2006, 61:935-939.
    • (2006) Thorax , vol.61 , pp. 935-939
    • Lokke, A.1    Lange, P.2    Scharling, H.3    Fabricius, P.4    Vestbo, J.5
  • 4
    • 33646202932 scopus 로고    scopus 로고
    • COPD: The dangerous underestimate of 15%
    • Rennard S.I., Vestbo J. COPD: The dangerous underestimate of 15%. Lancet 2006, 367:1216-1219.
    • (2006) Lancet , vol.367 , pp. 1216-1219
    • Rennard, S.I.1    Vestbo, J.2
  • 5
    • 34548317150 scopus 로고    scopus 로고
    • Dyspnea and activity limitation in COPD: Mechanical factors
    • O'Donnell D.E., Laveneziana P. Dyspnea and activity limitation in COPD: Mechanical factors. COPD 2007, 4:225-236.
    • (2007) COPD , vol.4 , pp. 225-236
    • O'Donnell, D.E.1    Laveneziana, P.2
  • 6
    • 36049019384 scopus 로고    scopus 로고
    • Characterisation of phenotypes based on severity of emphysema in chronic obstructive pulmonary disease
    • Makita H., Nasuhara Y., Nagai K., Ito Y., Hasegawa M., Betsuyaku T., et al. Characterisation of phenotypes based on severity of emphysema in chronic obstructive pulmonary disease. Thorax 2007, 62:932-937.
    • (2007) Thorax , vol.62 , pp. 932-937
    • Makita, H.1    Nasuhara, Y.2    Nagai, K.3    Ito, Y.4    Hasegawa, M.5    Betsuyaku, T.6
  • 8
    • 34250175841 scopus 로고    scopus 로고
    • Household air pollution from coal and biomass fuels in China: Measurements, health impacts, and interventions
    • Zhang J.J., Smith K.R. Household air pollution from coal and biomass fuels in China: Measurements, health impacts, and interventions. Environ Health Perspect 2007, 115:848-855.
    • (2007) Environ Health Perspect , vol.115 , pp. 848-855
    • Zhang, J.J.1    Smith, K.R.2
  • 9
    • 34548220492 scopus 로고    scopus 로고
    • Passive smoking exposure and risk of COPD among adults in China: The Guangzhou Biobank Cohort Study
    • Yin P., Jiang C.Q., Cheng K.K., Lam T.H., Lam K.H., Miller M.R., et al. Passive smoking exposure and risk of COPD among adults in China: The Guangzhou Biobank Cohort Study. Lancet 2007, 370:751-757.
    • (2007) Lancet , vol.370 , pp. 751-757
    • Yin, P.1    Jiang, C.Q.2    Cheng, K.K.3    Lam, T.H.4    Lam, K.H.5    Miller, M.R.6
  • 10
    • 0036794862 scopus 로고    scopus 로고
    • Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
    • Donaldson G.C., Seemungal T.A., Bhowmik A., Wedzicha J.A. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002, 57:847-852.
    • (2002) Thorax , vol.57 , pp. 847-852
    • Donaldson, G.C.1    Seemungal, T.A.2    Bhowmik, A.3    Wedzicha, J.A.4
  • 11
    • 0035070005 scopus 로고    scopus 로고
    • Bacterial infection in chronic obstructive pulmonary disease in 2000: A state-of-the-art review
    • Sethi S., Murphy T.F. Bacterial infection in chronic obstructive pulmonary disease in 2000: A state-of-the-art review. Clin Microbiol Rev 2001, 14:336-363.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 336-363
    • Sethi, S.1    Murphy, T.F.2
  • 12
    • 33847032182 scopus 로고    scopus 로고
    • Childhood chest illness and the rate of decline of adult lung function between ages 35 and 45 years
    • Marossy A.E., Strachan D.P., Rudnicka A.R., Anderson H.R. Childhood chest illness and the rate of decline of adult lung function between ages 35 and 45 years. Am J Respir Crit Care Med 2007, 175:355-359.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 355-359
    • Marossy, A.E.1    Strachan, D.P.2    Rudnicka, A.R.3    Anderson, H.R.4
  • 14
    • 43749124657 scopus 로고    scopus 로고
    • HIV associated pulmonary emphysema: A review of the literature and inquiry into its mechanism
    • Petrache I., Diab K., Knox K.S., Twigg H.L., Stephens R.S., Flores S., et al. HIV associated pulmonary emphysema: A review of the literature and inquiry into its mechanism. Thorax 2008, 63:463-469.
    • (2008) Thorax , vol.63 , pp. 463-469
    • Petrache, I.1    Diab, K.2    Knox, K.S.3    Twigg, H.L.4    Stephens, R.S.5    Flores, S.6
  • 15
    • 0017402583 scopus 로고
    • The natural history of chronic airflow obstruction
    • Fletcher C., Peto R. The natural history of chronic airflow obstruction. BMJ 1977, 1:1645-1648.
    • (1977) BMJ , vol.1 , pp. 1645-1648
    • Fletcher, C.1    Peto, R.2
  • 18
    • 2542609402 scopus 로고    scopus 로고
    • Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture
    • Holz O., Zuhlke I., Jaksztat E., Muller K.C., Welker L., Nakashima M., et al. Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture. Eur Respir J 2004, 24:575-579.
    • (2004) Eur Respir J , vol.24 , pp. 575-579
    • Holz, O.1    Zuhlke, I.2    Jaksztat, E.3    Muller, K.C.4    Welker, L.5    Nakashima, M.6
  • 20
    • 33847788971 scopus 로고    scopus 로고
    • Morphological mechanism of the development of pulmonary emphysema in klotho mice
    • Sato A., Hirai T., Imura A., Kita N., Iwano A., Muro S., et al. Morphological mechanism of the development of pulmonary emphysema in klotho mice. Proc Natl Acad Sci USA 2007, 104:2361-2365.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2361-2365
    • Sato, A.1    Hirai, T.2    Imura, A.3    Kita, N.4    Iwano, A.5    Muro, S.6
  • 21
    • 33748297499 scopus 로고    scopus 로고
    • Senescence marker protein-30 protects mice lungs from oxidative stress, aging and smoking
    • Sato T., Seyama K., Sato Y., Mori H., Souma S., Akiyoshi T., et al. Senescence marker protein-30 protects mice lungs from oxidative stress, aging and smoking. Am J Respir Crit Care Med 2006, 174:530-537.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 530-537
    • Sato, T.1    Seyama, K.2    Sato, Y.3    Mori, H.4    Souma, S.5    Akiyoshi, T.6
  • 22
    • 33751213597 scopus 로고    scopus 로고
    • Cigarette smoke inhibits alveolar repair: A mechanism for the development of emphysema
    • Rennard S.I., Togo S., Holz O. Cigarette smoke inhibits alveolar repair: A mechanism for the development of emphysema. Proc Am Thorac Soc 2006, 3:703-708.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 703-708
    • Rennard, S.I.1    Togo, S.2    Holz, O.3
  • 23
    • 0024344149 scopus 로고
    • Effects of starvation and refeeding on elastase-induced emphysema
    • Sahebjami H., Domino M. Effects of starvation and refeeding on elastase-induced emphysema. J Appl Physiol 1989, 66:2611-2616.
    • (1989) J Appl Physiol , vol.66 , pp. 2611-2616
    • Sahebjami, H.1    Domino, M.2
  • 24
    • 0020585494 scopus 로고
    • Cigarette smoke blocks cross-linking of elastin in vitro
    • Laurent P., JanoffA., Kagan H.M. Cigarette smoke blocks cross-linking of elastin in vitro. Chest 1983, 83:63S-65S.
    • (1983) Chest , vol.83
    • Laurent, P.1    Janoff, A.2    Kagan, H.M.3
  • 27
    • 2942720573 scopus 로고    scopus 로고
    • The nature of small-airway obstruction in chronic obstructive pulmonary disease
    • Hogg J.C., Chu F., Utokaparch S., Woods R., Elliott W.M., Buzatu L., et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004, 350:2645-2653.
    • (2004) N Engl J Med , vol.350 , pp. 2645-2653
    • Hogg, J.C.1    Chu, F.2    Utokaparch, S.3    Woods, R.4    Elliott, W.M.5    Buzatu, L.6
  • 28
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
    • Barnes P.J., Shapiro S.D., Pauwels R.A. Chronic obstructive pulmonary disease: Molecular and cellular mechanisms. Eur Respir J 2003, 22:672-688.
    • (2003) Eur Respir J , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 29
    • 10644266789 scopus 로고    scopus 로고
    • Mediators of chronic obstructive pulmonary disease
    • Barnes P.J. Mediators of chronic obstructive pulmonary disease. Pharmacol Rev 2004, 56:515-548.
    • (2004) Pharmacol Rev , vol.56 , pp. 515-548
    • Barnes, P.J.1
  • 30
    • 33748580720 scopus 로고    scopus 로고
    • Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease
    • Donnelly L.E., Barnes P.J. Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease. Trends Pharmacol Sci 2006, 27:546-553.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 546-553
    • Donnelly, L.E.1    Barnes, P.J.2
  • 31
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes P.J. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 2008, 8:183-192.
    • (2008) Nat Rev Immunol , vol.8 , pp. 183-192
    • Barnes, P.J.1
  • 32
    • 0037320195 scopus 로고    scopus 로고
    • Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease
    • Fabbri L.M., Romagnoli M., Corbetta L., Casoni G., Busljetic K., Turato G., et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003, 167:418-424.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 418-424
    • Fabbri, L.M.1    Romagnoli, M.2    Corbetta, L.3    Casoni, G.4    Busljetic, K.5    Turato, G.6
  • 33
    • 0033711405 scopus 로고    scopus 로고
    • Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease
    • Papi A., Romagnoli M., Baraldo S., Braccioni F., Guzzinati I., Saetta M., et al. Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000, 162:1773-1777.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1773-1777
    • Papi, A.1    Romagnoli, M.2    Baraldo, S.3    Braccioni, F.4    Guzzinati, I.5    Saetta, M.6
  • 34
    • 0034032761 scopus 로고    scopus 로고
    • Comparison of the structural and inflammatory features of COPD and asthma
    • Jeffery P.K. Comparison of the structural and inflammatory features of COPD and asthma. Chest 2000, 117:251S-260S.
    • (2000) Chest , vol.117
    • Jeffery, P.K.1
  • 35
    • 33645507720 scopus 로고    scopus 로고
    • The role of airway secretions in COPD: Pathophysiology, epidemiology and pharmacotherapeutic options
    • Rogers D.F. The role of airway secretions in COPD: Pathophysiology, epidemiology and pharmacotherapeutic options. COPD 2005, 2:341-353.
    • (2005) COPD , vol.2 , pp. 341-353
    • Rogers, D.F.1
  • 37
    • 38449105137 scopus 로고    scopus 로고
    • Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: A pooled analysis
    • Gamble E., Grootendorst D.C., Hattotuwa K., O'Shaughnessy T., Ram F.S., Qiu Y., et al. Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: A pooled analysis. Eur Respir J 2007, 30:467-471.
    • (2007) Eur Respir J , vol.30 , pp. 467-471
    • Gamble, E.1    Grootendorst, D.C.2    Hattotuwa, K.3    O'Shaughnessy, T.4    Ram, F.S.5    Qiu, Y.6
  • 38
    • 0036118262 scopus 로고    scopus 로고
    • Epidermal growth factor receptor family in lung cancer and premalignancy
    • Franklin W.A., Veve R., Hirsch F.R., Helfrich B.A., Bunn P.A. Epidermal growth factor receptor family in lung cancer and premalignancy. Semin Oncol 2002, 29:3-14.
    • (2002) Semin Oncol , vol.29 , pp. 3-14
    • Franklin, W.A.1    Veve, R.2    Hirsch, F.R.3    Helfrich, B.A.4    Bunn, P.A.5
  • 39
    • 0026761415 scopus 로고
    • Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP)
    • Mio T., Nagai S., Kitaichi M., Kawatani A., Izumi T. Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP). Chest 1992, 102:832-837.
    • (1992) Chest , vol.102 , pp. 832-837
    • Mio, T.1    Nagai, S.2    Kitaichi, M.3    Kawatani, A.4    Izumi, T.5
  • 40
    • 0034524384 scopus 로고    scopus 로고
    • Fibroblast contractility: Usual interstitial pneumonia and nonspecific interstitial pneumonia
    • Miki H., Mio T., Nagai S., Hoshino Y., Nagao T., Kitaichi M., et al. Fibroblast contractility: Usual interstitial pneumonia and nonspecific interstitial pneumonia. Am J Respir Crit Care Med 2000, 162:2259-2264.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 2259-2264
    • Miki, H.1    Mio, T.2    Nagai, S.3    Hoshino, Y.4    Nagao, T.5    Kitaichi, M.6
  • 41
    • 0030071687 scopus 로고    scopus 로고
    • Differences in interleukin-8 and tumor necrosis factor-a in induced sputum from patients with chronic obstructive pulmonary disease or asthma
    • Keatings V.M., Collins P.D., Scott D.M., Barnes P.J. Differences in interleukin-8 and tumor necrosis factor-a in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996, 153:530-534.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 530-534
    • Keatings, V.M.1    Collins, P.D.2    Scott, D.M.3    Barnes, P.J.4
  • 43
    • 33748053351 scopus 로고    scopus 로고
    • Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF)
    • Vlahos R., Bozinovski S., Hamilton J.A., Anderson G.P. Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF). Pharmacol Ther 2006, 112:106-115.
    • (2006) Pharmacol Ther , vol.112 , pp. 106-115
    • Vlahos, R.1    Bozinovski, S.2    Hamilton, J.A.3    Anderson, G.P.4
  • 44
    • 0028265386 scopus 로고
    • Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis
    • Di Stefano A., Maestrelli P., Roggeri A., Turato G., Calabro S., Potena A., et al. Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis. Am J Respir Crit Care Med 1994, 149:803-810.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 803-810
    • Di Stefano, A.1    Maestrelli, P.2    Roggeri, A.3    Turato, G.4    Calabro, S.5    Potena, A.6
  • 45
    • 0036311347 scopus 로고    scopus 로고
    • Elevated levels of the chemokines GRO-a and MCP-1 in sputum samples from COPD patients
    • Traves S.L., Culpitt S., Russell R.E.K., Barnes P.J., Donnelly L.E. Elevated levels of the chemokines GRO-a and MCP-1 in sputum samples from COPD patients. Thorax 2002, 57:590-595.
    • (2002) Thorax , vol.57 , pp. 590-595
    • Traves, S.L.1    Culpitt, S.2    Russell, R.E.K.3    Barnes, P.J.4    Donnelly, L.E.5
  • 46
    • 0031059872 scopus 로고    scopus 로고
    • Granulocyte activation markers in induced sputum: Comparison between chronic obstructive pulmonary disease, asthma and normal subjects
    • Keatings V.M., Barnes P.J. Granulocyte activation markers in induced sputum: Comparison between chronic obstructive pulmonary disease, asthma and normal subjects. Am J Respir Crit Care Med 1997, 155:449-453.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 449-453
    • Keatings, V.M.1    Barnes, P.J.2
  • 47
    • 0345073628 scopus 로고    scopus 로고
    • Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD
    • Biernacki W.A., Kharitonov S.A., Barnes P.J. Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD. Thorax 2003, 58:294-298.
    • (2003) Thorax , vol.58 , pp. 294-298
    • Biernacki, W.A.1    Kharitonov, S.A.2    Barnes, P.J.3
  • 48
    • 0035137558 scopus 로고    scopus 로고
    • Granulocyte inflammatory markers and airway infection during acute exacerbation of chronic obstructive pulmonary disease
    • Aaron S.D., Angel J.B., Lunau M., Wright K., Fex C., Le Saux N., et al. Granulocyte inflammatory markers and airway infection during acute exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001, 163:349-355.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 349-355
    • Aaron, S.D.1    Angel, J.B.2    Lunau, M.3    Wright, K.4    Fex, C.5    Le Saux, N.6
  • 49
    • 33750627155 scopus 로고    scopus 로고
    • Macrophages as orchestrators of COPD
    • Barnes P.J. Macrophages as orchestrators of COPD. COPD 2004, 1:59-70.
    • (2004) COPD , vol.1 , pp. 59-70
    • Barnes, P.J.1
  • 51
    • 0036006795 scopus 로고    scopus 로고
    • Emphysematous lung destruction by cigarette smoke. The effects of latent adenoviral infection on the lung inflammatory response
    • Meshi B., Vitalis T.Z., Ionescu D., Elliott W.M., Liu C., Wang X.D., et al. Emphysematous lung destruction by cigarette smoke. The effects of latent adenoviral infection on the lung inflammatory response. Am J Respir Cell Mol Biol 2002, 26:52-57.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 52-57
    • Meshi, B.1    Vitalis, T.Z.2    Ionescu, D.3    Elliott, W.M.4    Liu, C.5    Wang, X.D.6
  • 53
    • 0037383155 scopus 로고    scopus 로고
    • Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations
    • Caramori G., Romagnoli M., Casolari P., Bellettato C., Casoni G., Boschetto P., et al. Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations. Thorax 2003, 58:348-351.
    • (2003) Thorax , vol.58 , pp. 348-351
    • Caramori, G.1    Romagnoli, M.2    Casolari, P.3    Bellettato, C.4    Casoni, G.5    Boschetto, P.6
  • 54
    • 3442895601 scopus 로고    scopus 로고
    • Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: A role for CXCR2
    • Traves S.L., Smith S.J., Barnes P.J., Donnelly L.E. Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: A role for CXCR2. J Leukoc Biol 2004, 76:441-450.
    • (2004) J Leukoc Biol , vol.76 , pp. 441-450
    • Traves, S.L.1    Smith, S.J.2    Barnes, P.J.3    Donnelly, L.E.4
  • 55
    • 15744363493 scopus 로고    scopus 로고
    • An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema
    • Grumelli S., Corry D.B., Song L-X., Song L., Green L., Huh J., et al. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 2004, 1:75-83.
    • (2004) PLoS Med , vol.1 , pp. 75-83
    • Grumelli, S.1    Corry, D.B.2    Song, L.-X.3    Song, L.4    Green, L.5    Huh, J.6
  • 56
    • 0036724480 scopus 로고    scopus 로고
    • Increased p21CIP1/WAF1 and B cell lymphoma leukemia-xL expression and reduced apoptosis in alveolar macrophages from smokers
    • Tomita K., Caramori G., Lim S., Ito K., Hanazawa T., Oates T., et al. Increased p21CIP1/WAF1 and B cell lymphoma leukemia-xL expression and reduced apoptosis in alveolar macrophages from smokers. Am J Respir Crit Care Med 2002, 166:724-731.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 724-731
    • Tomita, K.1    Caramori, G.2    Lim, S.3    Ito, K.4    Hanazawa, T.5    Oates, T.6
  • 57
    • 0031045482 scopus 로고    scopus 로고
    • Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD
    • Keatings V.M., Jatakanon A., Worsdell Y.M., Barnes P.J. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997, 155:542-548.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 542-548
    • Keatings, V.M.1    Jatakanon, A.2    Worsdell, Y.M.3    Barnes, P.J.4
  • 58
    • 0037216753 scopus 로고    scopus 로고
    • Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease
    • Culpitt S.V., Rogers D.F., Shah P., de Matos C., Russell R.E., Donnelly L.E., et al. Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003, 167:24-31.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 24-31
    • Culpitt, S.V.1    Rogers, D.F.2    Shah, P.3    de Matos, C.4    Russell, R.E.5    Donnelly, L.E.6
  • 59
    • 21044458874 scopus 로고    scopus 로고
    • Decreased histone deacetylase activity in chronic obstructive pulmonary disease
    • Ito K., Ito M., Elliott W.M., Cosio B., Caramori G., Kon O.M., et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005, 352:1967-1976.
    • (2005) N Engl J Med , vol.352 , pp. 1967-1976
    • Ito, K.1    Ito, M.2    Elliott, W.M.3    Cosio, B.4    Caramori, G.5    Kon, O.M.6
  • 60
    • 33144482007 scopus 로고    scopus 로고
    • Reduced histone deacetylase in COPD: Clinical implications
    • Barnes P.J. Reduced histone deacetylase in COPD: Clinical implications. Chest 2006, 129:151-155.
    • (2006) Chest , vol.129 , pp. 151-155
    • Barnes, P.J.1
  • 61
    • 0035402125 scopus 로고    scopus 로고
    • Exacerbations of Bronchitis: Bronchial eosinophilia and gene expression for interleukin-4, interleukin-5, and eosinophil chemoattractants
    • Zhu J., Qiu Y.S., Majumdar S., Gamble E., Matin D., Turato G., et al. Exacerbations of Bronchitis: Bronchial eosinophilia and gene expression for interleukin-4, interleukin-5, and eosinophil chemoattractants. Am J Respir Crit Care Med 2001, 164:109-116.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 109-116
    • Zhu, J.1    Qiu, Y.S.2    Majumdar, S.3    Gamble, E.4    Matin, D.5    Turato, G.6
  • 62
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • Hammad H., Lambrecht B.N. Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008, 8:193-204.
    • (2008) Nat Rev Immunol , vol.8 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 65
    • 15744364004 scopus 로고    scopus 로고
    • Characterization of T lymphocytes in chronic obstructive pulmonary disease
    • Barnes P.J., Cosio M.G. Characterization of T lymphocytes in chronic obstructive pulmonary disease. PLoS Med 2004, 1:25-27.
    • (2004) PLoS Med , vol.1 , pp. 25-27
    • Barnes, P.J.1    Cosio, M.G.2
  • 67
    • 0037092562 scopus 로고    scopus 로고
    • Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease
    • Saetta M., Mariani M., Panina-Bordignon P., Turato G., Buonsanti C., Baraldo S., et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002, 165:1404-1409.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1404-1409
    • Saetta, M.1    Mariani, M.2    Panina-Bordignon, P.3    Turato, G.4    Buonsanti, C.5    Baraldo, S.6
  • 68
    • 0036257614 scopus 로고    scopus 로고
    • Inflammation of the airways and lung parenchyma in COPD: Role of T cells
    • Cosio M.G., Majo J., Cosio M.G. Inflammation of the airways and lung parenchyma in COPD: Role of T cells. Chest 2002, 121:160S-165S.
    • (2002) Chest , vol.121
    • Cosio, M.G.1    Majo, J.2    Cosio, M.G.3
  • 69
    • 0037114131 scopus 로고    scopus 로고
    • Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: Parallels with human disease
    • Takubo Y., Guerassimov A., Ghezzo H., Triantafillopoulos A., Bates J.H., Hoidal J.R., et al. Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: Parallels with human disease. Am J Respir Crit Care Med 2002, 166:1596-1603.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1596-1603
    • Takubo, Y.1    Guerassimov, A.2    Ghezzo, H.3    Triantafillopoulos, A.4    Bates, J.H.5    Hoidal, J.R.6
  • 70
    • 0033966777 scopus 로고    scopus 로고
    • Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome
    • Hashimoto S., Kobayashi A., Kooguchi K., Kitamura Y., Onodera H., Nakajima H. Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome. Am J Respir Crit Care Med 2000, 161:237-243.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 237-243
    • Hashimoto, S.1    Kobayashi, A.2    Kooguchi, K.3    Kitamura, Y.4    Onodera, H.5    Nakajima, H.6
  • 72
    • 0034949094 scopus 로고    scopus 로고
    • Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
    • Majo J., Ghezzo H., Cosio M.G. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J 2001, 17:946-953.
    • (2001) Eur Respir J , vol.17 , pp. 946-953
    • Majo, J.1    Ghezzo, H.2    Cosio, M.G.3
  • 76
    • 33646922638 scopus 로고    scopus 로고
    • Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease
    • Barczyk A., Pierzchala W., Kon O.M., Cosio B., Adcock I.M., Barnes P.J. Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease. J Allergy Clin Immunol 2006, 117:1484-1492.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1484-1492
    • Barczyk, A.1    Pierzchala, W.2    Kon, O.M.3    Cosio, B.4    Adcock, I.M.5    Barnes, P.J.6
  • 78
    • 34047261246 scopus 로고    scopus 로고
    • Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease
    • Vijayanand P., Seumois G., Pickard C., Powell R.M., Angco G., Sammut D., et al. Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N Engl J Med 2007, 356:1410-1422.
    • (2007) N Engl J Med , vol.356 , pp. 1410-1422
    • Vijayanand, P.1    Seumois, G.2    Pickard, C.3    Powell, R.M.4    Angco, G.5    Sammut, D.6
  • 80
    • 0344088442 scopus 로고    scopus 로고
    • Neutrophil chemotactic activity of sputum from patients with COPD: Role of interleukin 8 and leukotriene B4
    • Beeh K.M., Kornmann O., Buhl R., Culpitt S.V., Giembycz M.A., Barnes P.J. Neutrophil chemotactic activity of sputum from patients with COPD: Role of interleukin 8 and leukotriene B4. Chest 2003, 123:1240-1247.
    • (2003) Chest , vol.123 , pp. 1240-1247
    • Beeh, K.M.1    Kornmann, O.2    Buhl, R.3    Culpitt, S.V.4    Giembycz, M.A.5    Barnes, P.J.6
  • 81
    • 23244438717 scopus 로고    scopus 로고
    • Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: Cellular and molecular mechanisms
    • Rahman I. Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: Cellular and molecular mechanisms. Cell Biochem Biophys 2005, 43:167-188.
    • (2005) Cell Biochem Biophys , vol.43 , pp. 167-188
    • Rahman, I.1
  • 82
    • 10044235066 scopus 로고    scopus 로고
    • Isoprostanes: Markers and mediators of oxidative stress
    • Montuschi P., Barnes P.J., Roberts L.J. Isoprostanes: Markers and mediators of oxidative stress. FASEB J 2004, 18:1791-1800.
    • (2004) FASEB J , vol.18 , pp. 1791-1800
    • Montuschi, P.1    Barnes, P.J.2    Roberts, L.J.3
  • 83
    • 15244356847 scopus 로고    scopus 로고
    • Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
    • Rangasamy T., Cho C.Y., Thimmulappa R.K., Zhen L., Srisuma S.S., Kensler T.W., et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004, 114:1248-1259.
    • (2004) J Clin Invest , vol.114 , pp. 1248-1259
    • Rangasamy, T.1    Cho, C.Y.2    Thimmulappa, R.K.3    Zhen, L.4    Srisuma, S.S.5    Kensler, T.W.6
  • 84
    • 27744450995 scopus 로고    scopus 로고
    • Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema
    • Ishii Y., Itoh K., Morishima Y., Kimura T., Kiwamoto T., Iizuka T., et al. Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema. J Immunol 2005, 175:6968-6975.
    • (2005) J Immunol , vol.175 , pp. 6968-6975
    • Ishii, Y.1    Itoh, K.2    Morishima, Y.3    Kimura, T.4    Kiwamoto, T.5    Iizuka, T.6
  • 85
    • 0037423725 scopus 로고    scopus 로고
    • The effect of oxidative stress on histone acetylation and IL-8 release
    • Tomita K., Barnes P.J., Adcock I.M. The effect of oxidative stress on histone acetylation and IL-8 release. Biochem Biophys Res Commun 2003, 301:572-577.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 572-577
    • Tomita, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 86
    • 0842308109 scopus 로고    scopus 로고
    • Oxidative stress reduces histone deacetylase (HDAC)2 activity and enhances IL-8 gene expression: Role of tyrosine nitration
    • Ito K., Tomita T., Barnes P.J., Adcock I.M. Oxidative stress reduces histone deacetylase (HDAC)2 activity and enhances IL-8 gene expression: Role of tyrosine nitration. Biochem Biophys Res Commun 2004, 315:240-245.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 240-245
    • Ito, K.1    Tomita, T.2    Barnes, P.J.3    Adcock, I.M.4
  • 90
    • 0031150005 scopus 로고    scopus 로고
    • Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions
    • Boivin G.P., Ormsby I., Jones-Carson J., O'Toole B.A., Doetschman T. Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions. Transgenic Res 1997, 6:197-202.
    • (1997) Transgenic Res , vol.6 , pp. 197-202
    • Boivin, G.P.1    Ormsby, I.2    Jones-Carson, J.3    O'Toole, B.A.4    Doetschman, T.5
  • 91
    • 3242799550 scopus 로고    scopus 로고
    • Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis
    • Bonniaud P., Kolb M., Galt T., Robertson J., Robbins C., Stampfli M., et al. Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol 2004, 173:2099-2108.
    • (2004) J Immunol , vol.173 , pp. 2099-2108
    • Bonniaud, P.1    Kolb, M.2    Galt, T.3    Robertson, J.4    Robbins, C.5    Stampfli, M.6
  • 92
    • 3242706027 scopus 로고    scopus 로고
    • Cigarette smoke Induces MUC5AC mucin overproduction via tumor necrosis factor-a converting enzyme in human airway epithelial (NCI-H292) cells
    • Shao M.X., Nakanaga T., Nadel J.A. Cigarette smoke Induces MUC5AC mucin overproduction via tumor necrosis factor-a converting enzyme in human airway epithelial (NCI-H292) cells. Am J Physiol Lung Cell Mol Physiol 2004, 287:L420-L427.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287
    • Shao, M.X.1    Nakanaga, T.2    Nadel, J.A.3
  • 93
    • 8544250584 scopus 로고    scopus 로고
    • Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium
    • Burgel P.R., Nadel J.A. Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax 2004, 59:992-996.
    • (2004) Thorax , vol.59 , pp. 992-996
    • Burgel, P.R.1    Nadel, J.A.2
  • 94
    • 7044224186 scopus 로고    scopus 로고
    • VEGF obstructs the lungs
    • Rothenberg M.E. VEGF obstructs the lungs. Nat Med 2004, 10:1041-1042.
    • (2004) Nat Med , vol.10 , pp. 1041-1042
    • Rothenberg, M.E.1
  • 95
    • 18844434417 scopus 로고    scopus 로고
    • Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
    • Petrache I., Natarajan V., Zhen L., Medler T.R., Richter A.T., Cho C., et al. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 2005, 11:491-498.
    • (2005) Nat Med , vol.11 , pp. 491-498
    • Petrache, I.1    Natarajan, V.2    Zhen, L.3    Medler, T.R.4    Richter, A.T.5    Cho, C.6
  • 96
    • 0036010527 scopus 로고    scopus 로고
    • Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease
    • Russell R.E., Culpitt S.V., DeMatos C., Donnelly L., Smith M., Wiggins J., et al. Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2002, 26:602-609.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 602-609
    • Russell, R.E.1    Culpitt, S.V.2    DeMatos, C.3    Donnelly, L.4    Smith, M.5    Wiggins, J.6
  • 97
    • 0030823772 scopus 로고    scopus 로고
    • Requirement for macrophage metalloelastase for cigarette smoke-induced emphysema in mice
    • Hautamaki R.D., Kobayashi D.K., Senior R.M., Shapiro S.D. Requirement for macrophage metalloelastase for cigarette smoke-induced emphysema in mice. Science 1997, 277:2002-2004.
    • (1997) Science , vol.277 , pp. 2002-2004
    • Hautamaki, R.D.1    Kobayashi, D.K.2    Senior, R.M.3    Shapiro, S.D.4
  • 98
    • 0035077465 scopus 로고    scopus 로고
    • Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema
    • Imai K., Dalal S.S., Chen E.S., Downey R., Schulman L.L., Ginsburg M., et al. Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema. Am J Respir Crit Care Med 2001, 163:6-91.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 6-91
    • Imai, K.1    Dalal, S.S.2    Chen, E.S.3    Downey, R.4    Schulman, L.L.5    Ginsburg, M.6
  • 99
    • 33747834015 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: A systemic disease
    • Agusti A. Chronic obstructive pulmonary disease: A systemic disease. Proc Am Thorac Soc 2006, 3:478-481.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 478-481
    • Agusti, A.1
  • 100
    • 40549125613 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: A chronic systemic inflammatory disease
    • van Eeden S.F., Sin D.D. Chronic obstructive pulmonary disease: A chronic systemic inflammatory disease. Respiration 2008, 75:224-238.
    • (2008) Respiration , vol.75 , pp. 224-238
    • van Eeden, S.F.1    Sin, D.D.2
  • 101
    • 4444280869 scopus 로고    scopus 로고
    • Prospects for new drugs for chronic obstructive pulmonary disease
    • Barnes P.J., Hansel T.T. Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 2004, 364:985-996.
    • (2004) Lancet , vol.364 , pp. 985-996
    • Barnes, P.J.1    Hansel, T.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.