Killer cells in chronic obstructive pulmonary disease

Clinical Science

Volumn 114, Issue 7-8, 2008, Pages 533-541

  Fairclough, Lucy ^a   Urbanowicz, Richard A ^a   Corne, Jonathan ^b   Lamb, Jonathan R ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease (COPD); Cytokine; Lung; Natural killer cell; T cell receptor; T lymphoycyte

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; FAS LIGAND; GRANZYME; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; PERFORIN;

ADAPTIVE IMMUNITY; AIRWAY OBSTRUCTION; APOPTOSIS; BRONCHIOLITIS; CD8+ T LYMPHOCYTE; CELL INTERACTION; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOKINE RELEASE; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; KILLER CELL; LUNG PARENCHYMA; MORBIDITY; MORTALITY; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW; WORLD HEALTH ORGANIZATION; IMMUNOLOGY; IMMUNOPHENOTYPING; NATURAL KILLER CELL;

CYTOTOXICITY, IMMUNOLOGIC; HUMANS; IMMUNOPHENOTYPING; KILLER CELLS; KILLER CELLS, NATURAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 41949118067     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20070356     Document Type: Review

References (101)

1. Celli, B. R. and MacNee, W. (2004) Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur. Respir. J. 23, 932-946
2. World Health Organization (2007) COPD Factsheet No, 315, World Health Organization (ttp://www.who.int/mediacentre/factsheets/fs315/en/index.html)
3. Brown, C., Crombie, I. and Tunstall-Pedoe, H. (1994) Failure of cigarette smoking to explain international differences in mortality from chronic obstructive pulmonary disease. J. Epidemiol. Community Health 48, 134-139
4. Celli, B. R., Cote, C. C., Marin, J. M. et al. (2004) The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N. Engl. J. Med. 350, 1005-1012
5. Saetta, M., Di Stefano, A., Turato, G. et al. (1998) CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 157, 822-826
6. Finkelstein, R., Fraser, R. S., Ghezzo, H. and Cosio, M. G. (1995) Alveolar inflammation and its relation to emphysema in smokers. Am. J. Respir. Crit. Care Med. 152, 1666-1672
7. Finkelstein, R., Ma, H. D., Ghezzo, H., Whittaker, K., Fraser, R. S. and Cosio, M. G. (1995) Morphometry of small airways in smokers and its relationship to emphysema type and hyperresponsiveness. Am. J. Respir. Crit. Care Med. 152, 267-276
8. Bernard, S., LeBlanc, P., Whittom, F. et al. (1998) Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 158, 629-634
9. Rahman, I., Morrison, D., Donaldson, K. and MacNee, W. (1996) Systemic oxidative stress in asthma, COPD, and smokers. Am. J. Respir. Crit. Care Med. 154, 1055-1060
10. Kamischke, A., Kemper, D. E., Castel, M. A. et al. (1998) Testosterone levels in men with chronic obstructive pulmonary disease with or without glucocorticoid therapy. Eur. Respir. J. 11, 41-45
11. Ekberg-Jansson, A., Andersson, B., Avra, E., Nilsson, O. and Lofdahl, C. G. (2000) The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old. Respir. Med. 94, 264-272
12. Kim, W. D., Kim, W. S., Koh, Y. et al. (2002) Abnormal peripheral blood T-lymphocyte subsets in a subgroup of patients with COPD. Chest 122, 437-444
13. Leckie, M. J., Jenkins, G. R., Khan, J. et al. (2003) Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+). Thorax 58, 23-29
14. Lewis, S. A., Pavord, I. D., Stringer, J. R., Knox, A. J., Weiss, S. T. and Britton, J. R. (2001) The relation between peripheral blood leukocyte counts and respiratory symptoms, atopy, lung function, and airway responsiveness in adults. Chest 119, 105-114
15. Majori, M., Corradi, M., Caminati, A., Cacciani, G., Bertacco, S. and Pesci, A. (1999) Predominant TH1 cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 103, 458-462
16. Barcelo, B., Pons, J., Fuster, A. et al. (2006) Intracellular cytokine profile of T lymphocytes in patients with chronic obstructive pulmonary disease. Clin. Exp. Immunol. 145, 474-479
17. Prieto, A., Reyes, E., Bernstein, E. et al. (2001) Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferon). Am. J. Respir. Crit. Care Med. 163, 1578-1583
18. Zeidel, A., Beilin, B., Yardeni, I., Mayburd, E., Smirnov, G. and Bessler, H. (2002) Immune response in asymptomatic smokers. Acta Anaesthesiol. Scand. 46, 959-964
19. Majo, J., Ghezzo, H. and Cosio, M. (2001) Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur. Respir. J. 17, 946-953
20. Costabel, U., Maier, K., Teschler, H. and Wang, Y. M. (1992) Local immune components in chronic obstructive pulmonary disease. Respiration 59 (Suppl. 1), 17-19
21. Akbari, O., Faul, J., Hoyte, E. et al. (2006) CD4+ invariant T-cell-receptor+natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 1117-1129
22. Vijayanand, P., Seumois, G., Pickard, C. et al. (2007) Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N. Engl. J. Med. 356, 1410-1422
23. Suzuki, H., Punt, J. A., Granger, L. G. and Singer, A. (1995) Asymmetric signaling requirements for thymocyte commitment to the CD44- versus CD8+ T cell lineages: a new perspective on thymic commitment and selection. Immunity 2, 413-425
24. Lucas, B. and and Germain, R. N. (1996) Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. Immunity 5, 461-477
25. hi thymocytes. J. Exp. Med. 181, 1643-1651
26. int thymocytes with up-regulated levels of TCR-CD3. J. Immunol. 155, 3806-3814
27. Saetta, M., Turato, G., Maestrelli, P., Mapp, C. E. and Fabbri, L. M. (2001) Cellular and structural bases of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 163, 1304-1309
28. Retamales, I., Elliott, W. M., Meshi, B. et al. (2001) Amplification of inflammation in emphysema and its association with latent adenoviral infection. Am. J. Respir. Crit. Care Med. 164, 469-473
29. Saetta, M., Mariani, M., Panina-Bordignon, P. et al. (2002) Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 165, 1404-1409
30. Sempowski, G. D., Derdak, S. and Phipps, R. P. (1996) Interleukin-4 and interferon-γ discordantly regulate collagen biosynthesis by functionally distinct lung fibroblast subsets. J. Cell. Physiol. 167, 290-296
31. Baggiolini, M. (1998) Chemokines and leukocyte traffic. Nature 392, 565-568
32. Luster, M. I. and Simeonova, P. P. (1998) Asbestos induces inflammatory cytokines in the lung through redox sensitive transcription factors. Toxicol. Lett. 102-103, 271-275
33. D'Ambrosio, D., Mariani, M., Panina-Bordignon, P. and Sinigaglia, F. (2001) Chemokines and their receptors guiding T lymphocyte recruitment in lung inflammation. Am. J. Respir. Crit. Care Med. 164, 1266-1275
34. Spurrell, J. C., Wiehler, S., Zaheer, R. S., Sanders, S. P. and Proud, D. (2005) Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection. Am. J. Physiol. Lung Cell. Mol. Physiol. 289, L85-L95
35. Berke, G. (1994) The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects. Annu. Rev. Immunol. 12, 735-773
36. Hashimoto, S., Kobayashi, A., Kooguchi, K., Kitamura, Y., Onodera, H. and Nakajima, H. (2000) Upregulation of two death pathways of perforin/ granzyme and FasL/Fas in septic acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 161, 237-243
37. bright subset. Blood 97, 3146-3151
38. Cooper, M. A., Fehniger, T. A., Fuchs, A., Colonna, M. and Caligiuri, M. A. (2004) NK cell and DC interactions. Trends Immunol. 25, 47-52
39. Andoniou, C. E., van Dommelen, S. L., Voigt, V. et al. (2005) Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity. Nat. Immunol. 6, 1011-1019
40. Smyth, M. J., Cretney, E., Kelly, J. M. et al. (2005) Activation of NK cell cytotoxicity. Mol. Immunol. 42, 501-510
41. Nagler, A., Lanier, L. L., Cwirla, S. and Phillips, J. H. (1989) Comparative studies of human FcRIII-positive and negative natural killer cells. J. Immunol. 143, 3183-3191
42. Jacobs, R., Stoll, M., Stratmann, G., Leo, R., Link, H. and Schmidt, R. E. (1992) CD16- CD56+ natural killer cells after bone marrow transplantation. Blood 79, 3239-3244
43. bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J. Immunol. 173, 6418-6426
44. Smyth, M. J. and Nutt, S. L. (2006) IL-7 and the thymus dictate the NK cell 'labor market'. Nat. Immunol. 7, 1134-1136
45. Farag, S. S. and and Caligiuri, M. A. (2006) Human natural killer cell development and biology. Blood Rev. 20, 123-137
46. dim cells: role of contact with peripheral fibroblasts. J. Immunol. 179, 89-94
47. Bendelac, A., Bonneville, M. and Kearney, J. F. (2001) Autoreactivity by design: innate B and T lymphocytes. Nat. Rev. Immunol. 1, 177-186
48. Bendelac, A., Rivera, M. N., Park, S. H. and Roark, J. H. (1997) Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15, 535-562
49. Porcelli, S. A. and Modlin, R. L. (1999) The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu. Rev. Immunol. 17, 297-329
50. Godfrey, D. I., MacDonald, H. R., Kronenberg, M., Smyth, M. J. and Van Kaer, L. (2004) NKT cells: what's in a name? Nat. Rev. Immunol. 4, 231-237
51. Brigl, M. and Brenner, M. B. (2004) CD1: antigen presentation and T cell function. Annu. Rev. Immunol. 22, 817-890
52. Kronenberg, M. and Gapin, L. (2002) The unconventional lifestyle of NKT cells. Nat. Rev. Immunol. 2 8, 557-568
53. Emoto, M. and Kaufmann, S. H. (2003) Liver NKT cells: an account of heterogeneity. Trends Immunol. 24, 364-369
54. Norris, S., Doherty, D. G., Collins, C. et al. (1999) Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T cell receptor bearing cells. Hum. Immunol. 60, 20-31
55. Kenna, T., Golden-Mason, L., Porcelli, S. A. et al. (2003) NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells. J. Immunol. 171, 1775-1779
56. Oren, A., Husebo, C., Iversen, A. C. and Austgulen, R. (2005) A comparative study of immunomagnetic methods used for separation of human natural killer cells from peripheral blood. J. Immunol. Methods 303, 1-10
57. Bendelac, A., Lantz, O., Quimby, M. E., Yewdell, J. W., Bennink, J. R. and Brutkiewicz, R. R. (1995) CD1 recognition by mouse NK1+ T lymphocytes. Science 268, 863-865
58. Pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179, 1285-1295
59. Hammond, K. J. and Kronenberg, M. (2003) Natural killer T cells: natural or unnatural regulators of autoimmunity? Curr. Opin. Immunol. 15, 683-689
60. Smyth, M. J., Crowe, N. Y., Hayakawa, Y., Takeda, K., Yagita, H. and Godfrey, D. I. (2002) NKT cells: conductors of tumor immunity? Curr. Opin. Immunol. 14, 165-171
61. Skold, M. and Behar, S. M. (2003) Role of CD1d-restricted NKT cells in microbial immunity. Infect. Immun. 71, 5447-5455
62. Laloux, V., Beaudoin, L., Ronet, C. and Lehuen, A. (2002) Phenotypic and functional differences between NKT cells colonizing splanchnic and peripheral lymph nodes. J. Immunol. 168, 3251-3258
63. Takahashi, T., Nieda, M., Koezuka, Y. et al. (2000) Analysis of human Vα 24+ CD4+ NKT cells activated by α-glycosylceramide-pulsed monocyte-derived dendritic cells. J. Immunol. 164, 4458-4464
64. Takahashi, T., Chiba, S., Nieda, M. et al. (2002) Cutting edge: analysis of human Vα 24+CD8+ NK T cells activated by α-galactosylceramide- pulsed monocyte-derived dendritic cells. J. Immunol. 168, 3140-3144
65. Gumperz, J. E., Miyake, S., Yamamura, T. and Brenner, M. B. (2002) Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195, 625-636
66. Kim, C. H., Butcher, E. C. and Johnston, B. (2002) Distinct subsets of human Vα24-invariant NKT cells: cytokine responses and chemokine receptor expression. Trends Immunol. 23, 516-519
67. Lee, P. T., Benlagha, K., Teyton, L. and Bendelac, A. (2002) Distinct functional lineages of human Vα24 natural killer T cells. J. Exp. Med. 195, 637-641
68. Cardell, S. L. (2006) The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice. Clin. Exp. Immunol. 143, 194-202
69. Bendelac, A., Savage, P. B. and Teyton, L. (2007) The biology of NKT cells. Annu. Rev. Immunol. 25, 297-336
70. Wingender, G. and Kronenberg, M. (2008) The role of canonical natural killer T cells in mucosal immunity and inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 294, G1-G8
71. Treiner, E., Duban, L., Bahram, S. et al. (2003) Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422, 164-169
72. Kawano, T., Cui, J., Koezuka, Y. et al. (1997) CD1d-restricted and TCR-mediated activation of vα14 NKT cells by glycosylceramides. Science 278, 1626-1629
73. Zhou, D., Mattner, J., Cantu, III, C. et al. (2004) Lysosomal glycosphingolipid recognition by NKT cells. Science 306, 1786-1789
74. Cardell, S., Tangri, S., Chan, S., Kronenberg, M., Benoist, C. and Mathis, D. (1995) CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice. J. Exp. Med. 182, 993-1004
75. Zeng, D., Dick, M., Cheng, L. et al. (1998) Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokines. J. Exp. Med. 187, 525-536
76. Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M. and Bendelac, A. (1998) CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells. J. Immunol. 160, 3121-3127
77. Behar, S. M., Podrebarac, T. A., Roy, C. J., Wang, C. R. and Brenner, M. B. (1999) Diverse TCRs recognize murine CD1. J. Immunol. 162, 161-167
78. Skold, M., Faizunnessa, N. N., Wang, C. R. and Cardell, S. (2000) CD1d-specific NK1.1+ T cells with a transgenic variant TCR. J. Immunol. 165, 168-174
79. Stenstrom, M., Skold, M., Ericsson, A. et al. (2004) Surface receptors identify mouse NK1.1+ T cell subsets distinguished by function and T cell receptor type. Eur. J. Immunol. 34, 56-65
80. Duarte, N., Stenstrom, M., Campino, S. et al. (2004) Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells. J. Immunol. 173, 3112-3118
81. Park, S. H., Weiss, A., Benlagha, K., Kyin, T., Teyton, L. and Bendelac, A. (2001) The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J. Exp. Med. 193, 893-904
82. Gumperz, J. E., Roy, C., Makowska, A. et al. (2000) Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 12, 211-221
83. Makowska, A., Kawano, T., Taniguchi, M. and Cardell, S. (2000) Differences in the ligand specificity between CD1d-restricted T cells with limited and diverse T-cell receptor repertoire. Scand. J. Immunol. 52, 71-79
84. Jahng, A., Maricic, I., Aguilera, C., Cardell, S., Halder, R. C. and Kumar, V. (2004) Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 199, 947-957
85. Exley, M. A., Tahir, S. M., Cheng, O. et al. (2001) A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses. J. Immunol. 167, 5531-5534
86. Exley, M. A., He, Q., Cheng, O. et al. (2002) Cutting edge: compartmentalization of Th1-like noninvariant CD1d-reactive T cells in hepatitis C virus-infected liver. J. Immunol. 168, 1519-1523
87. Fuss, I. J., Heller, F., Boirivant, M. et al. (2004) Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J. Clin. Invest. 113, 1490-1497
88. Kawachi, I., Maldonado, J., Strader, C. and Gilfillan, S. (2006) MR1-restricted Vα19i mucosal-associated invariant T cells are innate T cells in the gut lamina propria that provide a rapid and diverse cytokine response. J. Immunol. 176, 1618-1627
89. Treiner, E., Duban, L., Moura, I. C., Hansen, T., Gilfillan, S. and Lantz, O. (2005) Mucosal-associated invariant T (MAIT) cells: an evolutionarily conserved T cell subset. Microbes Infect. 7, 552-559
90. Treiner, E. and Lantz, O. (2006) CD1d- and MR1-restricted invariant T cells: of mice and men. Curr. Opin. Immunol. 18, 519-526
91. Shimamura, M. and and Huang, Y. Y. (2002) Presence of a novel subset of NKT cells bearing an invariant V(α)19.1-J(α)26 TCRα chain. FEBS Lett. 516, 97-100
92. Okamoto, N., Kanie, O., Huang, Y. Y., Fujii, R., Watanabe, H. and Shimamura, M. (2005) Synthetic α-mannosyl ceramide as a potent stimulant for an NKT cell repertoire bearing the invariant Vα19-Jα26 TCR α chain. Chem. Biol. 12, 677-683
93. Shimamura, M., Huang, Y. Y., Okamoto, N. et al. (2007) Modulation of Vα19 NKT cell immune responses by α-mannosyl ceramide derivatives consisting of a series of modified sphingosines. Eur. J. Immunol. 37, 1836-1844
94. Shimamura, M., Huang, Y. Y., Okamoto, N. et al. (2007) Glycolipids with nonreducing end α-mannosyl residues that have the potential to activate invariant Vα19 NKT cells. FEBS J. 274, 2921-2932
95. Nikos, S. (2007) 'In the beginning' of COPD: is evolution important? Am. J. Respir. Crit. Care Med. 175, 423-424
96. Chrysofakis, G., Tzanakis, N., Kyriakoy, D. et al. (2004) Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD. Chest 125, 71-76
97. Vernooy, J. H., Moller, G. M., van Suylen, R. J. et al. (2007) Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 175, 464-472
98. Hodge, S., Hodge, G., Nairn, J., Holmes, M. and Reynolds, P. (2006) Increased airway granzyme b and perforin in current and ex-smoking COPD subjects. COPD 3, 179-187
99. Domagala-Kulawik, J., Hoser, G., Daprowska, M. and Chazan, R. (2006) Increased proportion of Fas positive CD8+ cells in peripheral blood of patients with COPD. Respir. Med. 101, 1338-1343
100. Panina-Bordignon, P., Papi, A., Mariani, M. et al. (2001) The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J. Clin. Invest. 107, 1357-1364
101. Barczyk, A., Pierzchała, W., Kon, O., Cosio, B., Adcock, I. and Barnes, P. (2006) Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 117, 1484-1492