-
1
-
-
33947206045
-
Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions
-
Andrew N, Insall RH. 2007. Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions. Nat. Cell Biol. 9:193-200
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 193-200
-
-
Andrew, N.1
Insall, R.H.2
-
2
-
-
33846962880
-
Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP
-
Bader S, Kortholt A, Van Haastert PJ. 2007. Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP. Biochem. J. 402:153-161
-
(2007)
Biochem J.
, vol.402
, pp. 153-161
-
-
Bader, S.1
Kortholt, A.2
Van Haastert, P.J.3
-
3
-
-
33750491282
-
Migration of zebrafish primordial germ cells: A role for myosin contraction and cytoplasmic flow
-
Blaser H, Reichman-Fried M, Castanon I, Dumstrei K, Marlow FL, et al 2006. Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev. Cell 11:613-627
-
(2006)
Dev. Cell
, vol.11
, pp. 613-627
-
-
Blaser, H.1
Reichman-Fried, M.2
Castanon, I.3
Dumstrei, K.4
Marlow, F.L.5
-
4
-
-
33749472179
-
Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum
-
Bolourani P, Spiegelman GB, Weeks G. 2006. Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum. Mol. Biol. Cell 17:4543-4550
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 4543-4550
-
-
Bolourani, P.1
Spiegelman, G.B.2
Weeks, G.3
-
5
-
-
44349156489
-
Rap1 activation in response to cAMP occurs downstream of Ras activation during Dictyostelium aggregation
-
Bolourani P, Spiegelman GB, Weeks G. 2008. Rap1 activation in response to cAMP occurs downstream of Ras activation during Dictyostelium aggregation. J. Biol. Chem. 283:10232-10240
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10232-10240
-
-
Bolourani, P.1
Spiegelman, G.B.2
Weeks, G.3
-
6
-
-
0037009436
-
A novel cGMP signaling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium
-
Bosgraaf L, Russcher H, Smith JL, Wessels D, Soll DR, Van Haastert PJ. 2002. A novel cGMP signaling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J. 21:4560-4570
-
(2002)
EMBO J
, vol.21
, pp. 4560-4570
-
-
Bosgraaf, L.1
Russcher, H.2
Smith, J.L.3
Wessels, D.4
Soll, D.R.5
Van Haastert, P.J.6
-
8
-
-
67649197971
-
The ordered extension of pseudopodia by amoeboid cells in the absence of external cues
-
Bosgraaf L, van Haastert PJ. 2009. The ordered extension of pseudopodia by amoeboid cells in the absence of external cues. PLoS One 4:e5253
-
(2009)
PLoS One
, vol.4
-
-
Bosgraaf, L.1
Van Haastert, P.J.2
-
9
-
-
19444363399
-
RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium
-
Bosgraaf L, Waijer A, Engel R, Visser AJ, Wessels D, et al. 2005. RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium. J. Cell Sci. 118:1899-1910
-
(2005)
J. Cell Sci.
, vol.118
, pp. 1899-1910
-
-
Bosgraaf, L.1
Waijer, A.2
Engel, R.3
Visser, A.J.4
Wessels, D.5
-
10
-
-
0041519055
-
Dynamic organization of the actin system in the motile cells of Dictyostelium
-
Bretschneider T, Jonkman J, Kohler J, Medalia O, Barisic K, et al. 2002. Dynamic organization of the actin system in the motile cells of Dictyostelium. J. Muscle Res. Cell Motil. 23:639-649
-
(2002)
J. Muscle Res. Cell Motil.
, vol.23
, pp. 639-649
-
-
Bretschneider, T.1
Jonkman, J.2
Kohler, J.3
Medalia, O.4
Barisic, K.5
-
11
-
-
0035336844
-
Signaling at zero G: G-protein-independent functions for 7-TM receptors
-
Brzostowski JA, Kimmel AR. 2001. Signaling at zero G: G-protein-independent functions for 7-TM receptors. Trends Biochem. Sci. 26:291-297
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 291-297
-
-
Brzostowski, J.A.1
Kimmel, A.R.2
-
12
-
-
33749473004
-
Nonadaptive regulation of ERK2 in Dictyostelium: Implications for mechanisms of cAMP relay
-
Brzostowski JA, Kimmel AR. 2006. Nonadaptive regulation of ERK2 in Dictyostelium: implications for mechanisms of cAMP relay. Mol. Biol. Cell 17:4220-4227
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 4220-4227
-
-
Brzostowski, J.A.1
Kimmel, A.R.2
-
13
-
-
1842783708
-
A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement
-
Brzostowski JA, Parent CA, Kimmel AR. 2004. A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement. Genes. Dev. 18:805-815
-
(2004)
Genes. Dev.
, vol.18
, pp. 805-815
-
-
Brzostowski, J.A.1
Parent, C.A.2
Kimmel, A.R.3
-
14
-
-
0028933878
-
Agonist-induced loss of ligand binding is correlated with phosphorylation of cAR1, a G protein-coupled chemoattractant receptor from Dictyostelium
-
Caterina MJ, Devreotes PN, Borleis J, Hereld D. 1995. Agonist-induced loss of ligand binding is correlated with phosphorylation of cAR1, a G protein-coupled chemoattractant receptor from Dictyostelium. J. Biol. Chem. 270:8667-8672
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8667-8672
-
-
Caterina, M.J.1
Devreotes, P.N.2
Borleis, J.3
Hereld, D.4
-
15
-
-
34047134459
-
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis
-
Chen L, Iijima M, Tang M, Landree MA, Huang YE, et al. 2007. PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis. Dev. Cell 12:603-614
-
(2007)
Dev. Cell
, vol.12
, pp. 603-614
-
-
Chen, L.1
Iijima, M.2
Tang, M.3
Landree, M.A.4
Huang, Y.E.5
-
16
-
-
0344796392
-
Two phases of actin polymerization display different dependencieson PI(3,4, 5)P3 accumulation and have unique roles during chemotaxis
-
Chen L, Janetopoulos C, Huang YE, Iijima M, Borleis J, Devreotes PN. 2003. Two phases of actin polymerization display different dependencieson PI(3, 4, 5)P3 accumulation and have unique roles during chemotaxis. Mol. Biol. Cell 14:5028-5037
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 5028-5037
-
-
Chen, L.1
Janetopoulos, C.2
Huang, Y.E.3
Iijima, M.4
Borleis, J.5
Devreotes, P.N.6
-
17
-
-
0030028743
-
Signaling through chemoattractant receptors in Dictyostelium
-
Chen MY, Insall RH, Devreotes PN. 1996. Signaling through chemoattractant receptors in Dictyostelium. Trends Genet. 12:52-57
-
(1996)
Trends Genet.
, vol.12
, pp. 52-57
-
-
Chen, M.Y.1
Insall, R.H.2
Devreotes, P.N.3
-
18
-
-
0030722988
-
Anovel cytosolic regulator, Pianissimo, is required for chemoat-tractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium
-
Chen MY, LongY, Devreotes PN. 1997. Anovel cytosolic regulator, Pianissimo, is required for chemoat-tractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium. Genes. Dev. 11:3218-3231
-
(1997)
Genes. Dev.
, vol.11
, pp. 3218-3231
-
-
Chen, M.Y.1
Longy Devreotes, P.N.2
-
19
-
-
0033230933
-
PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis
-
Chung CY, Firtel RA. 1999. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol. 147:559-576
-
(1999)
J. Cell Biol.
, vol.147
, pp. 559-576
-
-
Chung, C.Y.1
Firtel, R.A.2
-
20
-
-
0034625002
-
Role of Rac in controlling the actin cy-toskeleton and chemotaxis in motile cells
-
Chung CY, Lee S, Briscoe C, Ellsworth C, Firtel RA. 2000. Role of Rac in controlling the actin cy-toskeleton and chemotaxis in motile cells. Proc. Natl. Acad. Sci. USA 97:5225-5230
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5225-5230
-
-
Chung, C.Y.1
Lee, S.2
Briscoe, C.3
Ellsworth, C.4
Firtel, R.A.5
-
21
-
-
0035947085
-
Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa
-
Chung CY, Potikyan G, Firtel RA 2001. Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Mol. Cell 7:937-947
-
(2001)
Mol. Cell
, vol.7
, pp. 937-947
-
-
Chung, C.Y.1
Potikyan, G.2
Firtel, R.A.3
-
22
-
-
33750515228
-
Mechanically induced actin-mediated rocketing of phagosomes
-
Clarke M, Muller-Taubenberger A, Anderson KI, Engel U, Gerisch G. 2006. Mechanically induced actin-mediated rocketing of phagosomes. Mol. Biol. Cell 17:4866-4875
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 4866-4875
-
-
Clarke, M.1
Muller-Taubenberger, A.2
Anderson, K.I.3
Engel, U.4
Gerisch, G.5
-
23
-
-
12544249887
-
The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis
-
Comer FI, Lippincott CK, Masbad JJ, Parent CA. 2005. The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis. Curr. Biol. 15:134-139
-
(2005)
Curr. Biol.
, vol.15
, pp. 134-139
-
-
Comer, F.I.1
Lippincott, C.K.2
Masbad, J.J.3
Parent, C.A.4
-
24
-
-
30044443294
-
Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase
-
Comer FI, Parent CA. 2006. Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase. Mol. Biol. Cell 17:357-366
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 357-366
-
-
Comer, F.I.1
Parent, C.A.2
-
25
-
-
0023688555
-
Actin polymerization and pseudopod extension during amoeboid chemotaxis
-
Condeelis J, Hall A, Bresnick A, Warren V, Hock R, et al. 1988. Actin polymerization and pseudopod extension during amoeboid chemotaxis. Cell Motil. Cytoskelet. 10:77-90
-
(1988)
Cell Motil. Cytoskelet.
, vol.10
, pp. 77-90
-
-
Condeelis, J.1
Hall, A.2
Bresnick, A.3
Warren, V.4
Hock, R.5
-
26
-
-
0022639281
-
Characterization of revertants of stmF mutants of Dictyostelium dis-coideum: Evidence that stmF is the structural gene of the cGMP-specific phosphodiesterase
-
Coukell MB, Cameron AM. 1986. Characterization of revertants of stmF mutants of Dictyostelium dis-coideum: evidence that stmF is the structural gene of the cGMP-specific phosphodiesterase. Dev. Genet. 6:163-177
-
(1986)
Dev. Genet.
, vol.6
, pp. 163-177
-
-
Coukell, M.B.1
Cameron, A.M.2
-
27
-
-
70349766884
-
In silico reconstitution of actin-based symmetry breaking and motility
-
Dayel MJ, Akin O, Landeryou M, Risca V, Mogilner A, Mullins RD. 2009. In silico reconstitution of actin-based symmetry breaking and motility. PLoS Biol. 7:e1000201
-
(2009)
PLoS Biol
, vol.7
-
-
Dayel, M.J.1
Akin, O.2
Landeryou, M.3
Risca, V.4
Mogilner, A.5
Mullins, R.D.6
-
28
-
-
0037743735
-
Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
-
Devreotes P, Janetopoulos C. 2003. Eukaryotic chemotaxis: distinctions between directional sensing and polarization. J. Biol. Chem. 278:20445-20448
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20445-20448
-
-
Devreotes, P.1
Janetopoulos, C.2
-
29
-
-
13544249968
-
In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis
-
Dormann D, Weijer G, Dowler S, Weijer CJ. 2004. In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis. J. Cell Sci. 117:6497-6509
-
(2004)
J Cell Sci.
, vol.117
, pp. 6497-6509
-
-
Dormann, D.1
Weijer, G.2
Dowler, S.3
Weijer, C.J.4
-
30
-
-
7244253099
-
Signaling pathways controlling primordial germ cell migration in zebrafish
-
DOI 10.1242/jcs.01362
-
Dumstrei K, Mennecke R, Raz E. 2004. Signaling pathways controlling primordial germ cell migration in zebrafish. J. Cell Sci. 117:4787-4795 (Pubitemid 39433445)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.20
, pp. 4787-4795
-
-
Dumstrei, K.1
Mennecke, R.2
Raz, E.3
-
31
-
-
0027372314
-
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo
-
Egelhoff TT, Lee RJ, Spudich JA 1993. Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell 75:363-371
-
(1993)
Cell
, vol.75
, pp. 363-371
-
-
Egelhoff, T.T.1
Lee, R.J.2
Spudich, J.A.3
-
32
-
-
18344395923
-
The genome of the social amoeba Dictyostelium discoideum
-
DOI 10.1038/nature03481
-
Eichinger L, Pachebat JA, Glockner G, Rajandream MA, Sucgang R, et al 2005. The genome of the social amoeba Dictyostelium discoideum. Nature 435:43-57 (Pubitemid 40655903)
-
(2005)
Nature
, vol.435
, Issue.7038
, pp. 43-57
-
-
Eichinger, I.1
Pachebat, J.A.2
Glockner, G.3
Rajandream, M.-A.4
Sucgang, R.5
Berriman, M.6
Song, J.7
Olsen, R.8
Szafranski, K.9
Xu, Q.10
Tunggal, B.11
Kummerfeld, S.12
Madera, M.13
Konfortov, B.A.14
Rivero, F.15
Bankier, A.T.16
Lehmann, R.17
Hamlin, N.18
Davies, R.19
Gaudet, P.20
Fey, P.21
Pilcher, K.22
Chen, G.23
Saunders, D.24
Sodergren, E.25
Davis, P.26
Kerhornou, A.27
Nie, X.28
Hall, N.29
Anjard, C.30
Hemphill, L.31
Bason, N.32
Farbrother, P.33
Desany, B.34
Just, E.35
Morio, T.36
Rost, R.37
Churcher, C.38
Cooper, J.39
Haydock, S.40
Van Driessche, N.41
Cronin, A.42
Goodhead, I.43
Muzny, D.44
Mourier, T.45
Pain, A.46
Lu, M.47
Harper, D.48
Lindsay, R.49
Hauser, H.50
James, K.51
Quiles, M.52
Madan Babu, M.53
Saito, T.54
Buchrieser, C.55
Wardroper, A.56
Felder, M.57
Thangavelu, M.58
Johnson, D.59
Knights, A.60
Loulseged, H.61
Mungall, K.62
Oliver, K.63
Price, C.64
Quail, M.A.65
Urushihara, H.66
Hernandez, J.67
Rabbinowitsch, E.68
Steffen, D.69
Sanders, M.70
Ma, J.71
Kohara, Y.72
Sharp, S.73
Simmonds, M.74
Spiegler, S.75
Tivey, A.76
Sugano, S.77
White, B.78
Walker, D.79
Woodward, J.80
Winckler, T.81
Tanaka, Y.82
Shaulsky, G.83
Schleicher, M.84
Weinstock, G.85
Rosenthal, A.86
Cox, E.C.87
Chisholm, R.L.88
Gibbs, R.89
Loomis, W.F.90
Platzer, M.91
Kay, R.R.92
Williams, J.93
Dear, P.H.94
Noegel, A.A.95
Barrell, B.96
Kuspa, A.97
more..
-
33
-
-
33845896298
-
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis
-
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, et al. 2007. PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat. Cell Biol. 9:86-91
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 86-91
-
-
Ferguson, G.J.1
Milne, L.2
Kulkarni, S.3
Sasaki, T.4
Walker, S.5
-
34
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S, Meili R, Lee S, Parry L, Firtel RA 2002. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109:611-623
-
(2002)
Cell
, vol.109
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
36
-
-
0025334574
-
In vivo receptor-mediated phosphorylation of a G protein in Dictyostelium
-
Gundersen RE, Devreotes PN 1990. In vivo receptor-mediated phosphorylation of a G protein in Dictyostelium. Science 248:591-593
-
(1990)
Science
, vol.248
, pp. 591-593
-
-
Gundersen, R.E.1
Devreotes, P.N.2
-
37
-
-
36549018694
-
Developmental morphology and chemotactic responses are dependent on G alpha subunit specificity in Dictyostelium
-
Hadwiger JA. 2007. Developmental morphology and chemotactic responses are dependent on G alpha subunit specificity in Dictyostelium. Dev. Biol. 312:1-12
-
(2007)
Dev. Biol.
, vol.312
, pp. 1-12
-
-
Hadwiger, J.A.1
-
38
-
-
33845932606
-
Role of RacC for the regulation of WASP and phos-phatidylinositol 3-kinase during chemotaxis of Dictyostelium
-
Han JW, Leeper L, Rivero F, Chung CY. 2006. Role of RacC for the regulation of WASP and phos-phatidylinositol 3-kinase during chemotaxis of Dictyostelium. J. Biol. Chem. 281:35224-35234
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 35224-35234
-
-
Han, J.W.1
Leeper, L.2
Rivero, F.3
Chung, C.Y.4
-
39
-
-
0028298289
-
Localization of ligand-induced phospho-rylation sites to serine clusters in the C-terminal domain of the Dictyostelium cAMP receptor, cAR1
-
Hereld D, Vaughan R, Kim JY, Borleis J, Devreotes P. 1994. Localization of ligand-induced phospho-rylation sites to serine clusters in the C-terminal domain of the Dictyostelium cAMP receptor, cAR1. J. Biol. Chem. 269:7036-7044
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7036-7044
-
-
Hereld, D.1
Vaughan, R.2
Kim, J.Y.3
Borleis, J.4
Devreotes, P.5
-
40
-
-
34247361650
-
Chemotaxis in the absence of PIP3 gradients
-
Hoeller O, Kay RR. 2007. Chemotaxis in the absence of PIP3 gradients. Curr. Biol. 17:813-817
-
(2007)
Curr. Biol.
, vol.17
, pp. 813-817
-
-
Hoeller, O.1
Kay, R.R.2
-
42
-
-
0038247883
-
Receptor-mediated regulation of PI3Ks confines PI(3,4, 5)P3 to the leading edge of chemotaxing cells
-
Huang YE, Iijima M, Parent CA, Funamoto S, Firtel RA, Devreotes P. 2003. Receptor-mediated regulation of PI3Ks confines PI(3, 4, 5)P3 to the leading edge of chemotaxing cells. Mol. Biol. Cell 14:1913-1922
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1913-1922
-
-
Huang, Y.E.1
Iijima, M.2
Parent, C.A.3
Funamoto, S.4
Firtel, R.A.5
Devreotes, P.6
-
43
-
-
3142766112
-
Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting
-
Hynes TR, Tang L, Mervine SM, Sabo JL, Yost EA, et al. 2004. Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting. J. Biol. Chem. 279:30279-30286
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30279-30286
-
-
Hynes, T.R.1
Tang, L.2
Mervine, S.M.3
Sabo, J.L.4
Yost, E.A.5
-
45
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Iijima M, Devreotes P 2002. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109:599-610
-
(2002)
Cell
, vol.109
, pp. 599-610
-
-
Iijima, M.1
Devreotes, P.2
-
46
-
-
0036773899
-
Temporal and spatial regulation of chemotaxis
-
Iijima M, Huang YE, Devreotes P. 2002. Temporal and spatial regulation of chemotaxis. Dev. Cell 3:469-478
-
(2002)
Dev. Cell
, vol.3
, pp. 469-478
-
-
Iijima, M.1
Huang, Y.E.2
Devreotes, P.3
-
47
-
-
1942501586
-
Novel mechanism of PTEN regulation by its phosphatidylinositol 4, 5-bisphosphate binding motif is critical for chemotaxis
-
Iijima M, Huang YE, Luo HR, Vazquez F, Devreotes PN. 2004. Novel mechanism of PTEN regulation by its phosphatidylinositol 4, 5-bisphosphate binding motif is critical for chemotaxis. J. Biol. Chem. 279:16606-16613
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16606-16613
-
-
Iijima, M.1
Huang, Y.E.2
Luo, H.R.3
Vazquez, F.4
Devreotes, P.N.5
-
48
-
-
52449120635
-
Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration
-
Inoue T, Meyer T. 2008. Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration. PLoS ONE 3:e3068
-
(2008)
PLoS ONE
, vol.3
-
-
Inoue, T.1
Meyer, T.2
-
49
-
-
0030156329
-
The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium
-
Insall RH, Borleis J, Devreotes PN. 1996. The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium. Curr. Biol. 6:719-729
-
(1996)
Curr. Biol.
, vol.6
, pp. 719-729
-
-
Insall, R.H.1
Borleis, J.2
Devreotes, P.N.3
-
50
-
-
70249116807
-
Actin dynamics at the leading edge: From simple machinery to complex networks
-
Insall RH, Machesky LM. 2009. Actin dynamics at the leading edge: from simple machinery to complex networks. Dev. Cell 17:310-322
-
(2009)
Dev. Cell
, vol.17
, pp. 310-322
-
-
Insall, R.H.1
MacHesky, L.M.2
-
52
-
-
53449096043
-
An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis
-
Isik N, Brzostowski JA, Jin T. 2008. An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis. Dev. Cell 15:590-602
-
(2008)
Dev. Cell
, vol.15
, pp. 590-602
-
-
Isik, N.1
Brzostowski, J.A.2
Jin, T.3
-
53
-
-
16244377763
-
Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis
-
Janetopoulos C, Borleis J, Vazquez F, Iijima M, Devreotes P. 2005. Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis. Dev. Cell 8:467-477
-
(2005)
Dev. Cell
, vol.8
, pp. 467-477
-
-
Janetopoulos, C.1
Borleis, J.2
Vazquez, F.3
Iijima, M.4
Devreotes, P.5
-
54
-
-
0035937571
-
Receptor-mediated activation of heterotrimeric G-proteins in living cells
-
Janetopoulos C, Jin T, Devreotes P 2001. Receptor-mediated activation of heterotrimeric G-proteins in living cells. Science 291:2408-2411
-
(2001)
Science
, vol.291
, pp. 2408-2411
-
-
Janetopoulos, C.1
Jin, T.2
Devreotes, P.3
-
55
-
-
2942687012
-
Chemoattractant-induced phosphatidylinositol 3, 4, 5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton
-
Janetopoulos C, Ma L, Devreotes PN, Iglesias PA. 2004. Chemoattractant-induced phosphatidylinositol 3, 4, 5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 101:8951-8956
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8951-8956
-
-
Janetopoulos, C.1
Ma, L.2
Devreotes, P.N.3
Iglesias, P.A.4
-
56
-
-
36849005496
-
Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells
-
Jeon TJ, Lee DJ, Lee S, Weeks G, Firtel RA. 2007. Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells. J. Cell Biol. 179:833-843
-
(2007)
J. Cell Biol.
, vol.179
, pp. 833-843
-
-
Jeon, T.J.1
Lee, D.J.2
Lee, S.3
Weeks, G.4
Firtel, R.A.5
-
57
-
-
33947718091
-
Rap1 controls cell adhesion and cell motility through the regulation of myosin II
-
DOI 10.1083/jcb.200607072
-
Jeon TJ, Lee DJ, Merlot S, Weeks G, Firtel RA. 2007. Rap1 controls cell adhesion and cell motility through the regulation of myosin II. J. Cell Biol. 176:1021-1033 (Pubitemid 46506974)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.7
, pp. 1021-1033
-
-
Jeon, T.J.1
Lee, D.-J.2
Merlot, S.3
Weeks, G.4
Firtel, R.A.5
-
58
-
-
0034635567
-
Localization of the G protein betagamma complex in living cells during chemotaxis
-
Jin T, Zhang N, Long Y, Parent CA, Devreotes PN 2000. Localization of the G protein betagamma complex in living cells during chemotaxis. Science 287:1034-1036
-
(2000)
Science
, vol.287
, pp. 1034-1036
-
-
Jin, T.1
Zhang, N.2
Long, Y.3
Parent, C.A.4
Devreotes, P.N.5
-
59
-
-
38949102726
-
Dynacortin facilitates polarization of chemotaxing cells
-
Kabacoff C, Xiong Y, Musib R, Reichl EM, Kim J, et al. 2007. Dynacortin facilitates polarization of chemotaxing cells. BMC Biol. 5:53
-
(2007)
BMC Biol.
, vol.5
, pp. 53
-
-
Kabacoff, C.1
Xiong, Y.2
Musib, R.3
Reichl, E.M.4
Kim, J.5
-
60
-
-
34247884549
-
Cyclic AMP signaling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs
-
Kae H, Kortholt A, Rehmann H, Insall RH, Van Haastert PJ, et al. 2007. Cyclic AMP signaling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs. EMBO Rep. 8:477-482
-
(2007)
EMBO Rep
, vol.8
, pp. 477-482
-
-
Kae, H.1
Kortholt, A.2
Rehmann, H.3
Insall, R.H.4
Van Haastert, P.J.5
-
61
-
-
4344571626
-
Chemoattractant-induced Ras activation during Dic-tyostelium aggregation
-
Kae H, Lim CJ, Spiegelman GB, Weeks G. 2004. Chemoattractant-induced Ras activation during Dic-tyostelium aggregation. EMBO Rep. 5:602-606
-
(2004)
EMBO Rep.
, vol.5
, pp. 602-606
-
-
Kae, H.1
Lim, C.J.2
Spiegelman, G.B.3
Weeks, G.4
-
62
-
-
47049110588
-
PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis
-
Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN. 2008. PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis. Curr. Biol. 18:1034-1043
-
(2008)
Curr. Biol.
, vol.18
, pp. 1034-1043
-
-
Kamimura, Y.1
Xiong, Y.2
Iglesias, P.A.3
Hoeller, O.4
Bolourani, P.5
Devreotes, P.N.6
-
64
-
-
34547663507
-
Cell motility and cytoskeletal regulation in invasion and metastasis
-
DOI 10.1007/s10911-007-9046-4
-
Kedrin D, van Rheenen J, Hernandez L, Condeelis J, Segall JE. 2007. Cell motility and cytoskeletal regulation in invasion and metastasis. J. Mammary Gland Biol. Neoplasia 12:143-152 (Pubitemid 47215432)
-
(2007)
Journal of Mammary Gland Biology and Neoplasia
, vol.12
, Issue.2-3
, pp. 143-152
-
-
Kedrin, D.1
Van Rheenen, J.2
Hernandez, L.3
Condeelis, J.4
Segall, J.E.5
-
65
-
-
34249111428
-
Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling
-
Keizer-Gunnink I, Kortholt A, Van Haastert PJ. 2007. Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling. J. Cell Biol. 177:579-585
-
(2007)
J. Cell Biol.
, vol.177
, pp. 579-585
-
-
Keizer-Gunnink, I.1
Kortholt, A.2
Van Haastert, P.J.3
-
66
-
-
0034054109
-
Functional overlap of the Dictyostelium RasG, RasD and RasB proteins
-
Khosla M, Spiegelman GB, Insall R, Weeks G. 2000. Functional overlap of the Dictyostelium RasG, RasD and RasB proteins. J. Cell Sci. 113(Pt. 8):1427-1434
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 8
, pp. 1427-1434
-
-
Khosla, M.1
Spiegelman, G.B.2
Insall, R.3
Weeks, G.4
-
67
-
-
0032080837
-
Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: Receptor subtypes activate common responses at different agonist concentrations
-
Kim JY, Borleis JA, Devreotes PN. 1998. Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: receptor subtypes activate common responses at different agonist concentrations. Dev. Biol. 197:117-128
-
(1998)
Dev. Biol.
, vol.197
, pp. 117-128
-
-
Kim, J.Y.1
Borleis, J.A.2
Devreotes, P.N.3
-
68
-
-
0031034484
-
Random mutagenesis of the cAMP chemoattractant receptor, cAR1, of Dictyostelium. Mutant classes that cause discrete shifts in agonist affinity and lock the receptor in a novel activational intermediate
-
Kim JY, Caterina MJ, Milne JL, Lin KC, Borleis JA, Devreotes PN. 1997. Random mutagenesis of the cAMP chemoattractant receptor, cAR1, of Dictyostelium. Mutant classes that cause discrete shifts in agonist affinity and lock the receptor in a novel activational intermediate. J. Biol. Chem. 272:2060-2068
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2060-2068
-
-
Kim, J.Y.1
Caterina, M.J.2
Milne, J.L.3
Lin, K.C.4
Borleis, J.A.5
Devreotes, P.N.6
-
69
-
-
0028052268
-
Random chimeragenesis of G-protein-coupled receptors. Mapping the affinity of the cAMP chemoattractant receptors in Dictyostelium
-
Kim JY, Devreotes PN. 1994. Random chimeragenesis of G-protein-coupled receptors. Mapping the affinity of the cAMP chemoattractant receptors in Dictyostelium. J. Biol. Chem. 269:28724-28731
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28724-28731
-
-
Kim, J.Y.1
Devreotes, P.N.2
-
70
-
-
0030766477
-
Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses
-
Kim JY, Soede RD, Schaap P, Valkema R, Borleis JA, et al. 1997. Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses. J. Biol. Chem. 272:27313-27318
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27313-27318
-
-
Kim, J.Y.1
Soede, R.D.2
Schaap, P.3
Valkema, R.4
Borleis, J.A.5
-
71
-
-
37049035944
-
Phospholipase Cregulation of phosphatidylinositol 3, 4, 5-trisphosphate-mediated chemotaxis
-
Kortholt A, King JS, Keizer-Gunnink I, Harwood AJ, Van Haastert PJ. 2007. Phospholipase Cregulation of phosphatidylinositol 3, 4, 5-trisphosphate- mediated chemotaxis. Mol. Biol. Cell 18:4772-4779
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4772-4779
-
-
Kortholt, A.1
King, J.S.2
Keizer-Gunnink, I.3
Harwood, A.J.4
Van Haastert, P.J.5
-
72
-
-
33747708176
-
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum
-
Kortholt A, Rehmann H, Kae H, Bosgraaf L, Keizer-Gunnink I, et al. 2006. Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum. J. Biol. Chem. 281:23367-23376
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23367-23376
-
-
Kortholt, A.1
Rehmann, H.2
Kae, H.3
Bosgraaf, L.4
Keizer-Gunnink, I.5
-
73
-
-
0037459060
-
Adenylyl cyclase localization regulates streaming during chemo-taxis
-
Kriebel PW, Barr VA, Parent CA 2003. Adenylyl cyclase localization regulates streaming during chemo-taxis. Cell 112:549-560
-
(2003)
Cell
, vol.112
, pp. 549-560
-
-
Kriebel, P.W.1
Barr, V.A.2
Parent, C.A.3
-
74
-
-
0026059565
-
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium
-
Kumagai A, Hadwiger JA, Pupillo M, Firtel RA. 1991. Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. J. Biol. Chem. 266:1220-1228
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1220-1228
-
-
Kumagai, A.1
Hadwiger, J.A.2
Pupillo, M.3
Firtel, R.A.4
-
75
-
-
26244438381
-
TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium
-
Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, et al. 2005. TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol. Biol. Cell 16:4572-4583
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4572-4583
-
-
Lee, S.1
Comer, F.I.2
Sasaki, A.3
McLeod, I.X.4
Duong, Y.5
-
76
-
-
9444297930
-
Dictyostelium PAKc is required for proper chemotaxis
-
Lee S, Rivero F, Park KC, Huang E, Funamoto S, Firtel RA. 2004. Dictyostelium PAKc is required for proper chemotaxis. Mol. Biol. Cell 15:5456-5469
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 5456-5469
-
-
Lee, S.1
Rivero, F.2
Park, K.C.3
Huang, E.4
Funamoto, S.5
Firtel, R.A.6
-
77
-
-
51849167782
-
Understanding PTEN regulation: PIP2, polarity and protein stability
-
Leslie NR, Batty IH, Maccario H, Davidson L, Downes CP. 2008. Understanding PTEN regulation: PIP2, polarity and protein stability. Oncogene 27:5464-5476
-
(2008)
Oncogene
, vol.27
, pp. 5464-5476
-
-
Leslie, N.R.1
Batty, I.H.2
MacCario, H.3
Davidson, L.4
Downes, C.P.5
-
78
-
-
33745594814
-
Directional sensing in eukaryotic chemotaxis: A balanced inactivation model
-
Levine H, Kessler DA, Rappel WJ. 2006. Directional sensing in eukaryotic chemotaxis: a balanced inactivation model. Proc. Natl. Acad. Sci. USA 103:9761-9766
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9761-9766
-
-
Levine, H.1
Kessler, D.A.2
Rappel, W.J.3
-
79
-
-
2342548658
-
Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration
-
Liang W, Licate L, Warrick H, Spudich J, Egelhoff T. 2002. Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration. BMC Cell Biol. 3:19
-
(2002)
BMC Cell Biol
, vol.3
, pp. 19
-
-
Liang, W.1
Licate, L.2
Warrick, H.3
Spudich, J.4
Egelhoff, T.5
-
80
-
-
2442526725
-
Periodic signaling controlled by an oscillatory circuit that includes protein kinases ERK2 and PKA
-
Maeda M, Lu S, Shaulsky G, Miyazaki Y, Kuwayama H, et al 2004. Periodic signaling controlled by an oscillatory circuit that includes protein kinases ERK2 and PKA. Science 304:875-878
-
(2004)
Science
, vol.304
, pp. 875-878
-
-
Maeda, M.1
Lu, S.2
Shaulsky, G.3
Miyazaki, Y.4
Kuwayama, H.5
-
81
-
-
51349153846
-
The Roco protein family: A functional perspective
-
Marin I, van Egmond WN, van Haastert PJ. 2008. The Roco protein family: a functional perspective. FASEB J. 22:3103-3110
-
(2008)
FASEB J.
, vol.22
, pp. 3103-3110
-
-
Marin, I.1
Van Egmond, W.N.2
Van Haastert, P.J.3
-
82
-
-
0032823984
-
Orientation of chemotactic cells and growth cones: Models and mechanisms
-
Meinhardt H. 1999. Orientation of chemotactic cells and growth cones: models and mechanisms. J. Cell Sci. 112(Pt. 17):2867-2874
-
(1999)
J. Cell Sci.
, vol.112
, Issue.PART 17
, pp. 2867-2874
-
-
Meinhardt, H.1
-
83
-
-
0041327718
-
Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways
-
Merlot S, Firtel RA. 2003. Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J. Cell Sci. 116:3471-3478
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3471-3478
-
-
Merlot, S.1
Firtel, R.A.2
-
84
-
-
0027416555
-
2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism
-
2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism. Mol. Biol. Cell 4:283-292
-
(1993)
Mol. Biol. Cell
, vol.4
, pp. 283-292
-
-
Milne, J.L.1
Devreotes, P.N.2
-
87
-
-
44649140579
-
Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions
-
Mondal S, Bakthavatsalam D, Steimle P, Gassen B, Rivero F, Noegel AA. 2008. Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions. J. Cell Biol. 181:747-760
-
(2008)
J. Cell Biol.
, vol.181
, pp. 747-760
-
-
Mondal, S.1
Bakthavatsalam, D.2
Steimle, P.3
Gassen, B.4
Rivero, F.5
Noegel, A.A.6
-
88
-
-
0026895972
-
Streamer F mutants and chemotaxis of Dictyostelium
-
Newell PC, Liu G 1992. Streamer F mutants and chemotaxis of Dictyostelium. Bioessays 14:473-479
-
(1992)
Bioessays
, vol.14
, pp. 473-479
-
-
Newell, P.C.1
Liu, G.2
-
89
-
-
61949094973
-
Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility
-
Para A, Krischke M, Merlot S, Shen Z, Oberholzer M, et al. 2009. Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility. Mol. Biol. Cell 20:699-707
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 699-707
-
-
Para, A.1
Krischke, M.2
Merlot, S.3
Shen, Z.4
Oberholzer, M.5
-
90
-
-
0032475863
-
G protein signaling events are activated at the leading edge of chemotactic cells
-
Parent CA, Blacklock BJ, Froehlich WM, Murphy DB, Devreotes PN 1998. G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95:81-91
-
(1998)
Cell
, vol.95
, pp. 81-91
-
-
Parent, C.A.1
Blacklock, B.J.2
Froehlich, W.M.3
Murphy, D.B.4
Devreotes, P.N.5
-
91
-
-
0033617576
-
A cell's sense of direction
-
Parent CA, Devreotes PN 1999. A cell's sense of direction. Science 284:765-770
-
(1999)
Science
, vol.284
, pp. 765-770
-
-
Parent, C.A.1
Devreotes, P.N.2
-
92
-
-
8444247968
-
Rac regulation of chemotaxis and morphogenesis in Dictyostelium
-
Park KC, Rivero F, Meili R, Lee S, Apone F, Firtel RA. 2004. Rac regulation of chemotaxis and morphogenesis in Dictyostelium. EMBO J. 23:4177-4189
-
(2004)
EMBO J
, vol.23
, pp. 4177-4189
-
-
Park, K.C.1
Rivero, F.2
Meili, R.3
Lee, S.4
Apone, F.5
Firtel, R.A.6
-
93
-
-
0026504354
-
Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development
-
Pitt GS, Milona N, Borleis J, Lin KC, Reed RR, Devreotes PN 1992. Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell 69:305-315
-
(1992)
Cell
, vol.69
, pp. 305-315
-
-
Pitt, G.S.1
Milona, N.2
Borleis, J.3
Lin, K.C.4
Reed, R.R.5
Devreotes, P.N.6
-
94
-
-
0034866573
-
A diffusion-translocation model for gradient sensing by chemotactic cells
-
Postma M, Van Haastert PJ. 2001. A diffusion-translocation model for gradient sensing by chemotactic cells. Biophys. J. 81:1314-1323
-
(2001)
Biophys J.
, vol.81
, pp. 1314-1323
-
-
Postma, M.1
Van Haastert, P.J.2
-
95
-
-
67649464358
-
PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells
-
Pramanik MK, Iijima M, Iwadate Y, Yumura S. 2009. PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells. Genes Cells 14:821-834
-
(2009)
Genes Cells
, vol.14
, pp. 821-834
-
-
Pramanik, M.K.1
Iijima, M.2
Iwadate, Y.3
Yumura, S.4
-
96
-
-
58849102128
-
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN
-
Rahdar M, Inoue T, Meyer T, Zhang J, Vazquez F, Devreotes PN. 2009. A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. Proc. Natl. Acad. Sci. USA 106:480-485
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 480-485
-
-
Rahdar, M.1
Inoue, T.2
Meyer, T.3
Zhang, J.4
Vazquez, F.5
Devreotes, P.N.6
-
97
-
-
19644371017
-
Dictyostelium LIS1 is a centro-somal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics
-
Rehberg M, Kleylein-Sohn J, Faix J, Ho TH, Schulz I, Graf R. 2005. Dictyostelium LIS1 is a centro-somal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics. Mol. Biol. Cell 16:2759-2771
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2759-2771
-
-
Rehberg, M.1
Kleylein-Sohn, J.2
Faix, J.3
Ho, T.H.4
Schulz, I.5
Graf, R.6
-
98
-
-
0037088636
-
Characterization of two unusual guanylyl cyclases from Dictyostelium
-
Roelofs J, Van Haastert PJ. 2002. Characterization of two unusual guanylyl cyclases from Dictyostelium. J. Biol. Chem. 277:9167-9174
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9167-9174
-
-
Roelofs, J.1
Van Haastert, P.J.2
-
99
-
-
8444221934
-
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
-
Sasaki AT, Chun C, Takeda K, Firtel RA. 2004. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167:505-518
-
(2004)
J. Cell Biol.
, vol.167
, pp. 505-518
-
-
Sasaki, A.T.1
Chun, C.2
Takeda, K.3
Firtel, R.A.4
-
100
-
-
33744928091
-
Mechanisms of gradient sensing and chemotaxis: Conserved pathways, diverse regulation
-
Schneider IC, Haugh JM. 2006. Mechanisms of gradient sensing and chemotaxis: conserved pathways, diverse regulation. Cell Cycle 5:1130-1134
-
(2006)
Cell Cycle
, vol.5
, pp. 1130-1134
-
-
Schneider, I.C.1
Haugh, J.M.2
-
101
-
-
0035951831
-
Recruitment of a specific amoeboid myosin i isoform to the plasma membrane in chemotactic Dictyostelium cells
-
Senda S, Lee SF, Cote GP, Titus MA. 2001. Recruitment of a specific amoeboid myosin I isoform to the plasma membrane in chemotactic Dictyostelium cells. J. Biol. Chem. 276:2898-2904
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2898-2904
-
-
Senda, S.1
Lee, S.F.2
Cote, G.P.3
Titus, M.A.4
-
102
-
-
0028286341
-
Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cARs). Evidence for involvement of cAR1 in aggregative gene expression
-
Soede RD, Insall RH, Devreotes PN, Schaap P 1994. Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cARs). Evidence for involvement of cAR1 in aggregative gene expression. Development 120:1997-2002
-
(1994)
Development
, vol.120
, pp. 1997-2002
-
-
Soede, R.D.1
Insall, R.H.2
Devreotes, P.N.3
Schaap, P.4
-
103
-
-
33750324227
-
RacG regulates morphology, phagocytosis, and chemotaxis, Eukaryot
-
Somesh BP, Vlahou G, Iijima M, Insall RH, Devreotes P, Rivero F 2006. RacG regulates morphology, phagocytosis, and chemotaxis. Eukaryot. Cell 5:1648-1663
-
(2006)
Cell
, vol.5
, pp. 1648-1663
-
-
Somesh, B.P.1
Vlahou, G.2
Iijima, M.3
Insall, R.H.4
Devreotes, P.5
Rivero, F.6
-
104
-
-
0035337319
-
Recruitment of a myosin heavy chain kinase to actin-rich protrusions in Dictyostelium
-
Steimle PA, Yumura S, Cote GP, Medley QG, Polyakov MV, et al. 2001. Recruitment of a myosin heavy chain kinase to actin-rich protrusions in Dictyostelium. Curr. Biol. 11:708-713
-
(2001)
Curr. Biol.
, vol.11
, pp. 708-713
-
-
Steimle, P.A.1
Yumura, S.2
Cote, G.P.3
Medley, Q.G.4
Polyakov, M.V.5
-
105
-
-
44349180298
-
Moving towards a better understanding of chemotaxis
-
Stephens L, Milne L, Hawkins P. 2008. Moving towards a better understanding of chemotaxis. Curr. Biol. 18:R485-94
-
(2008)
Curr. Biol.
, vol.18
-
-
Stephens, L.1
Milne, L.2
Hawkins, P.3
-
106
-
-
0020060138
-
Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis
-
Swanson JA, Taylor DL 1982. Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis. Cell 28:225-232
-
(1982)
Cell
, vol.28
, pp. 225-232
-
-
Swanson, J.A.1
Taylor, D.L.2
-
107
-
-
50049103371
-
Tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis
-
Tang L, Franca-Koh J, Xiong Y, Chen MY, Long Y, et al. 2008. tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis. Genes. Dev. 22:2278-2290
-
(2008)
Genes. Dev.
, vol.22
, pp. 2278-2290
-
-
Tang, L.1
Franca-Koh, J.2
Xiong, Y.3
Chen, M.Y.4
Long, Y.5
-
108
-
-
0035955356
-
Single-molecule analysis of chemotactic signaling in Dictyostelium cells
-
DOI 10.1126/science.1063951
-
Ueda M, Sako Y, Tanaka T, Devreotes P, Yanagida T 2001. Single-molecule analysis of chemotactic signaling in Dictyostelium cells. Science 294:864-867 (Pubitemid 33032106)
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 864-867
-
-
Ueda, M.1
Sako, Y.2
Tanaka, T.3
Devreotes, P.4
Yanagida, T.5
-
109
-
-
57649178295
-
Intramolecular activation mechanism of the Dictyostelium LRRK2 homolog Roco protein GbpC
-
van Egmond WN, Kortholt A, Plak K, Bosgraaf L, Bosgraaf S, et al. 2008. Intramolecular activation mechanism of the Dictyostelium LRRK2 homolog Roco protein GbpC. J. Biol. Chem. 283:30412-30420
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30412-30420
-
-
Van Egmond, W.N.1
Kortholt, A.2
Plak, K.3
Bosgraaf, L.4
Bosgraaf, S.5
-
110
-
-
0035903161
-
The protein kinase YakA regulates G-protein-linked signaling responses during growth and development of Dictyostelium
-
van Es S, Weening KE, Devreotes PN. 2001. The protein kinase YakA regulates G-protein-linked signaling responses during growth and development of Dictyostelium. J. Biol. Chem. 276:30761-30765
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30761-30765
-
-
Van Es, S.1
Weening, K.E.2
Devreotes, P.N.3
-
111
-
-
0021773971
-
Guanine nucleotides modulate cell surface cAMP-binding sites in membranes from Dictyostelium discoideum
-
Van Haastert PJ. 1984. Guanine nucleotides modulate cell surface cAMP-binding sites in membranes from Dictyostelium discoideum. Biochem. Biophys. Res. Commun. 124:597-604
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.124
, pp. 597-604
-
-
Van Haastert, P.J.1
-
112
-
-
34249873508
-
Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis
-
van Haastert PJ, Keizer-Gunnink I, Kortholt A. 2007. Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis. J. Cell Biol. 177:809-816
-
(2007)
J. Cell Biol.
, vol.177
, pp. 809-816
-
-
Van Haastert, P.J.1
Keizer-Gunnink, I.2
Kortholt, A.3
-
113
-
-
0030737616
-
CGMP as second messenger during Dictyostelium chemotaxis
-
van Haastert PJ, Kuwayama H. 1997. cGMP as second messenger during Dictyostelium chemotaxis. FEBS Lett. 410:25-28
-
(1997)
FEBS Lett
, vol.410
, pp. 25-28
-
-
Van Haastert, P.J.1
Kuwayama, H.2
-
114
-
-
37249000008
-
EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells
-
van Rheenen J, Song X, van Roosmalen W, Cammer M, Chen X, et al. 2007. EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells. J. Cell Biol. 179:1247-1259
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1247-1259
-
-
Van Rheenen, J.1
Song, X.2
Van Roosmalen, W.3
Cammer, M.4
Chen, X.5
-
115
-
-
0024279294
-
Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum
-
Vaughan RA, Devreotes PN. 1988. Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum. J. Biol. Chem. 263:14538-14543
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 14538-14543
-
-
Vaughan, R.A.1
Devreotes, P.N.2
-
116
-
-
33644870152
-
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
-
Vazquez F, Matsuoka S, Sellers WR, Yanagida T, Ueda M, Devreotes PN. 2006. Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane. Proc. Natl. Acad. Sci. USA 103:3633-3638
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3633-3638
-
-
Vazquez, F.1
Matsuoka, S.2
Sellers, W.R.3
Yanagida, T.4
Ueda, M.5
Devreotes, P.N.6
-
117
-
-
55049102752
-
The GPI-anchored superoxide dismutase SodC is essential for regulating basal Ras activity and for chemotaxis of Dictyostelium discoideum
-
Veeranki S, Kim B, Kim L. 2008. The GPI-anchored superoxide dismutase SodC is essential for regulating basal Ras activity and for chemotaxis of Dictyostelium discoideum. J. Cell Sci. 121:3099-3108
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3099-3108
-
-
Veeranki, S.1
Kim, B.2
Kim, L.3
-
118
-
-
0034646916
-
Reaction-diffusion waves of actin filament polymerization/ depolymerization in Dictyostelium pseudopodium extension and cell locomotion
-
Vicker MG. 2000. Reaction-diffusion waves of actin filament polymerization/depolymerization in Dictyostelium pseudopodium extension and cell locomotion. Biophys. Chem. 84:87-98
-
(2000)
Biophys. Chem.
, vol.84
, pp. 87-98
-
-
Vicker, M.G.1
-
119
-
-
34548103595
-
Mechanisms of gradient detection: A comparison of axon pathfinding with eukaryotic cell migration
-
von Philipsborn A, Bastmeyer M. 2007. Mechanisms of gradient detection: a comparison of axon pathfinding with eukaryotic cell migration. Int. Rev. Cytol. 263:1-62
-
(2007)
Int. Rev. Cytol.
, vol.263
, pp. 1-62
-
-
Von Philipsborn, A.1
Bastmeyer, M.2
-
121
-
-
0030873976
-
Dictyostelium development in the absence of cAMP
-
Wang B, Kuspa A 1997. Dictyostelium development in the absence of cAMP. Science 277:251-254
-
(1997)
Science
, vol.277
, pp. 251-254
-
-
Wang, B.1
Kuspa, A.2
-
122
-
-
0037770197
-
Roles played by Ras subfamily proteins in the cell and developmental biology of microorganisms
-
Weeks G, Spiegelman GB. 2003. Roles played by Ras subfamily proteins in the cell and developmental biology of microorganisms. Cell Signal 15:901-909
-
(2003)
Cell Signal
, vol.15
, pp. 901-909
-
-
Weeks, G.1
Spiegelman, G.B.2
-
123
-
-
34548703094
-
Anactin-basedwavegenerator organizes cell motility
-
Weiner OD, Marganski WA, Wu LF, Altschuler SJ, Kirschner MW. 2007. Anactin-basedwavegenerator organizes cell motility. PLoS Biol. 5:e221
-
(2007)
PLoS Biol
, vol.5
-
-
Weiner, O.D.1
Marganski, W.A.2
Wu, L.F.3
Altschuler, S.J.4
Kirschner, M.W.5
-
124
-
-
0036308972
-
A PtdInsP(3)-and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
-
Weiner OD, Neilsen PO, Prestwich GD, Kirschner MW, Cantley LC, Bourne HR. 2002. A PtdInsP(3)-and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat. Cell Biol. 4:509-513
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 509-513
-
-
Weiner, O.D.1
Neilsen, P.O.2
Prestwich, G.D.3
Kirschner, M.W.4
Cantley, L.C.5
Bourne, H.R.6
-
125
-
-
34548258389
-
PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis
-
Wessels D, Lusche DF, Kuhl S, Heid P, Soll DR. 2007. PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. J. Cell Sci. 120:2517-2531
-
(2007)
J. Cell Sci.
, vol.120
, pp. 2517-2531
-
-
Wessels, D.1
Lusche, D.F.2
Kuhl, S.3
Heid, P.4
Soll, D.R.5
-
126
-
-
0023924075
-
Cell motility and chemo-taxis in Dictyostelium amebae lacking myosin heavy chain
-
Wessels D, Soll DR, Knecht D, Loomis WF, De Lozanne A, Spudich J. 1988. Cell motility and chemo-taxis in Dictyostelium amebae lacking myosin heavy chain. Dev. Biol. 128:164-177
-
(1988)
Dev. Biol.
, vol.128
, pp. 164-177
-
-
Wessels, D.1
Soll, D.R.2
Knecht, D.3
Loomis, W.F.4
De Lozanne, A.5
Spudich, J.6
-
127
-
-
0029020634
-
The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium
-
Wu L, Valkema R, Van Haastert PJ, Devreotes PN. 1995. The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium. J. Cell Biol. 129:1667-1675
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1667-1675
-
-
Wu, L.1
Valkema, R.2
Van Haastert, P.J.3
Devreotes, P.N.4
-
128
-
-
0030729285
-
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation
-
Xiao Z, Zhang N, Murphy DB, Devreotes PN. 1997. Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J. Cell Biol. 139:365-374
-
(1997)
J. Cell Biol.
, vol.139
, pp. 365-374
-
-
Xiao, Z.1
Zhang, N.2
Murphy, D.B.3
Devreotes, P.N.4
-
129
-
-
12844268483
-
Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium
-
Xu X, Meier-Schellersheim M, Jiao X, Nelson LE, Jin T. 2005. Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium. Mol. Biol. Cell 16:676-688
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 676-688
-
-
Xu, X.1
Meier-Schellersheim, M.2
Jiao, X.3
Nelson, L.E.4
Jin, T.5
-
130
-
-
64049086259
-
Akt2 is required for macrophage chemotaxis
-
Zhang B, Ma Y, Guo H, Sun B, Niu R, et al. 2009. Akt2 is required for macrophage chemotaxis. Eur. J. Immunol. 39:894-901
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 894-901
-
-
Zhang, B.1
Ma, Y.2
Guo, H.3
Sun, B.4
Niu, R.5
-
131
-
-
0037089078
-
Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity during Dictyostelium chemotaxis
-
Zhang H, Wessels D, Fey P, Daniels K, Chisholm RL, Soll DR. 2002. Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity during Dictyostelium chemotaxis. J. Cell Sci. 115:1733-1747
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1733-1747
-
-
Zhang, H.1
Wessels, D.2
Fey, P.3
Daniels, K.4
Chisholm, R.L.5
Soll, D.R.6
-
132
-
-
12844273394
-
Constitutively active G protein-coupled receptor mutants block Dictyostelium development
-
Zhang M, Goswami M, Hereld D. 2005. Constitutively active G protein-coupled receptor mutants block Dictyostelium development. Mol. Biol. Cell 16:562-572
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 562-572
-
-
Zhang, M.1
Goswami, M.2
Hereld, D.3
-
133
-
-
0034746777
-
Ggamma in Dictyostelium: Its role in localization of gbetagamma to the membrane is required for chemotaxis in shallow gradients
-
Zhang N, Long Y, Devreotes PN. 2001. Ggamma in Dictyostelium: Its role in localization of gbetagamma to the membrane is required for chemotaxis in shallow gradients. Mol. Biol. Cell 12:3204-3213
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3204-3213
-
-
Zhang, N.1
Long, Y.2
Devreotes, P.N.3
-
134
-
-
54149103045
-
Spatiotemporal regulation of Ras activity provides directional sensing
-
Zhang S, Charest PG, Firtel RA. 2008. Spatiotemporal regulation of Ras activity provides directional sensing. Curr. Biol. 18:1587-1593
-
(2008)
Curr. Biol.
, vol.18
, pp. 1587-1593
-
-
Zhang, S.1
Charest, P.G.2
Firtel, R.A.3
-
135
-
-
0030849454
-
Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42
-
Zigmond SH, Joyce M, Borleis J, Bokoch GM, Devreotes PN. 1997. Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42. J. Cell Biol. 138:363-374
-
(1997)
J. Cell Biol.
, vol.138
, pp. 363-374
-
-
Zigmond, S.H.1
Joyce, M.2
Borleis, J.3
Bokoch, G.M.4
Devreotes, P.N.5
|