메뉴 건너뛰기




Volumn 18, Issue 20, 2008, Pages 1587-1593

Spatiotemporal Regulation of Ras Activity Provides Directional Sensing

Author keywords

CELLBIO; SIGNALING

Indexed keywords

CHEMOTACTIC FACTOR; NEUROFIBROMIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTOZOAL PROTEIN; RAS PROTEIN; RASG PROTEIN, DICTYOSTELIUM;

EID: 54149103045     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2008.08.069     Document Type: Article
Times cited : (91)

References (27)
  • 1
    • 34548459788 scopus 로고    scopus 로고
    • Chemotaxis: Navigating by multiple signaling pathways
    • Van Haastert P.J.M., and Veltman D.M. Chemotaxis: Navigating by multiple signaling pathways. Sci. STKE 2007 (2007) pe40
    • (2007) Sci. STKE , vol.2007
    • Van Haastert, P.J.M.1    Veltman, D.M.2
  • 2
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki A.T., Chun C., Takeda K., and Firtel R.A. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167 (2004) 505-518
    • (2004) J. Cell Biol. , vol.167 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 4
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto S., Meili R., Lee S., Parry L., and Firtel R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109 (2002) 611-623
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 5
    • 47049110588 scopus 로고    scopus 로고
    • PIP(3)-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis
    • Kamimura Y., Xiong Y., Iglesias P.A., Hoeller O., Bolourani P., and Devreotes P.N. PIP(3)-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis. Curr. Biol. 18 (2008) 1034-1043
    • (2008) Curr. Biol. , vol.18 , pp. 1034-1043
    • Kamimura, Y.1    Xiong, Y.2    Iglesias, P.A.3    Hoeller, O.4    Bolourani, P.5    Devreotes, P.N.6
  • 6
  • 7
    • 33749472179 scopus 로고    scopus 로고
    • Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum
    • Bolourani P., Spiegelman G.B., and Weeks G. Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum. Mol. Biol. Cell 17 (2006) 4543-4550
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4543-4550
    • Bolourani, P.1    Spiegelman, G.B.2    Weeks, G.3
  • 9
    • 0035881962 scopus 로고    scopus 로고
    • RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation
    • Lim C.J., Spiegelman G.B., and Weeks G. RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation. EMBO J. 20 (2001) 4490-4499
    • (2001) EMBO J. , vol.20 , pp. 4490-4499
    • Lim, C.J.1    Spiegelman, G.B.2    Weeks, G.3
  • 10
    • 44649140579 scopus 로고    scopus 로고
    • Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions
    • Mondal S., Bakthavatsalam D., Steimle P., Gassen B., Rivero F., and Noegel A.A. Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions. J. Cell Biol. 181 (2008) 747-760
    • (2008) J. Cell Biol. , vol.181 , pp. 747-760
    • Mondal, S.1    Bakthavatsalam, D.2    Steimle, P.3    Gassen, B.4    Rivero, F.5    Noegel, A.A.6
  • 11
    • 0035858886 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium
    • Funamoto S., Milan K., Meili R., and Firtel R.A. Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium. J. Cell Biol. 153 (2001) 795-810
    • (2001) J. Cell Biol. , vol.153 , pp. 795-810
    • Funamoto, S.1    Milan, K.2    Meili, R.3    Firtel, R.A.4
  • 12
    • 0032475863 scopus 로고    scopus 로고
    • G protein signaling events are activated at the leading edge of chemotactic cells
    • Parent C.A., Blacklock B.J., Froehlich W.M., Murphy D.B., and Devreotes P.N. G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95 (1998) 81-91
    • (1998) Cell , vol.95 , pp. 81-91
    • Parent, C.A.1    Blacklock, B.J.2    Froehlich, W.M.3    Murphy, D.B.4    Devreotes, P.N.5
  • 13
    • 0033560747 scopus 로고    scopus 로고
    • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
    • Meili R., Ellsworth C., Lee S., Reddy T.B., Ma H., and Firtel R.A. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18 (1999) 2092-2105
    • (1999) EMBO J. , vol.18 , pp. 2092-2105
    • Meili, R.1    Ellsworth, C.2    Lee, S.3    Reddy, T.B.4    Ma, H.5    Firtel, R.A.6
  • 14
    • 21344464454 scopus 로고    scopus 로고
    • Signaling to cytoskeletal dynamics during chemotaxis
    • Affolter M., and Weijer C.J. Signaling to cytoskeletal dynamics during chemotaxis. Dev. Cell 9 (2005) 19-34
    • (2005) Dev. Cell , vol.9 , pp. 19-34
    • Affolter, M.1    Weijer, C.J.2
  • 16
    • 0037743735 scopus 로고    scopus 로고
    • Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
    • Devreotes P., and Janetopoulos C. Eukaryotic chemotaxis: Distinctions between directional sensing and polarization. J. Biol. Chem. 278 (2003) 20445-20448
    • (2003) J. Biol. Chem. , vol.278 , pp. 20445-20448
    • Devreotes, P.1    Janetopoulos, C.2
  • 17
    • 33745607882 scopus 로고    scopus 로고
    • Feedback signaling controls leading-edge formation during chemotaxis
    • Charest P.G., and Firtel R.A. Feedback signaling controls leading-edge formation during chemotaxis. Curr. Opin. Genet. Dev. 16 (2006) 339-347
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 339-347
    • Charest, P.G.1    Firtel, R.A.2
  • 18
    • 34047218649 scopus 로고    scopus 로고
    • A mathematical model for neutrophil gradient sensing and polarization
    • Onsum M., and Rao C.V. A mathematical model for neutrophil gradient sensing and polarization. PLoS Comput Biol 3 (2007) e36
    • (2007) PLoS Comput Biol , vol.3
    • Onsum, M.1    Rao, C.V.2
  • 21
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima M., and Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109 (2002) 599-610
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 22
    • 0034054109 scopus 로고    scopus 로고
    • Functional overlap of the Dictyostelium RasG, RasD and RasB proteins
    • Khosla M., Spiegelman G.B., Insall R., and Weeks G. Functional overlap of the Dictyostelium RasG, RasD and RasB proteins. J. Cell Sci. 113 (2000) 1427-1434
    • (2000) J. Cell Sci. , vol.113 , pp. 1427-1434
    • Khosla, M.1    Spiegelman, G.B.2    Insall, R.3    Weeks, G.4
  • 24
    • 1642328487 scopus 로고    scopus 로고
    • Making all the right moves: chemotaxis in neutrophils and Dictyostelium
    • Parent C.A. Making all the right moves: chemotaxis in neutrophils and Dictyostelium. Curr. Opin. Cell Biol. 16 (2004) 4-13
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 4-13
    • Parent, C.A.1
  • 25
    • 0033230933 scopus 로고    scopus 로고
    • PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis
    • Chung C.Y., and Firtel R.A. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol. 147 (1999) 559-576
    • (1999) J. Cell Biol. , vol.147 , pp. 559-576
    • Chung, C.Y.1    Firtel, R.A.2
  • 27
    • 0032462246 scopus 로고    scopus 로고
    • A computer-assisted system for reconstructing and interpreting the dynamic three-dimensional relationships of the outer surface, nucleus and pseudopods of crawling cells
    • Wessels D., Voss E., Von Bergen N., Burns R., Stites J., and Soll D.R. A computer-assisted system for reconstructing and interpreting the dynamic three-dimensional relationships of the outer surface, nucleus and pseudopods of crawling cells. Cell Motil. Cytoskeleton 41 (1998) 225-246
    • (1998) Cell Motil. Cytoskeleton , vol.41 , pp. 225-246
    • Wessels, D.1    Voss, E.2    Von Bergen, N.3    Burns, R.4    Stites, J.5    Soll, D.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.