Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 24, 2004, Pages 8951-8956

  Janetopoulos, Chris ^a   Ma, Lan ^b   Devreotes, Peter N ^a   Iglesias, Pablo A ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CHEMOATTRACTANT; LATRUNCULIN A; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL MOTILITY; CHEMOSENSITIVITY; CHEMOTAXIS; DICTYOSTELIUM DISCOIDEUM; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE; CELL POLARITY; CHEMOTACTIC FACTORS; CHEMOTAXIS; CYCLIC AMP; DICTYOSTELIUM; FLUORESCENCE; PHOSPHATIDYLINOSITOL PHOSPHATES; THIAZOLES; THIAZOLIDINES; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM;

EID: 2942687012     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0402152101     Document Type: Article

References (32)

1. Parent, C. A. & Devreotes, P. N. (1999) Science 284, 765-770.
2. Chung, C. Y., Funamoto, S. & Firtel, R. A. (2001) Trends Biochem. Sci. 26, 557-566.
3. Weiner, O. D. (2002) Curr. Opin. Cell Biol. 14, 196-202.
4. Carlos, T. M. (2001) J. Leukocyte BioL 70, 171-184.
5. Thelen, M. (2001) Nat. Immunol. 2, 129-134.
6. Murphy, P. M. (2001) N. Engl. J. Med. 345, 833-835.
7. Condeelis, J. S., Wyckoff, J. B., Bailly, M., Pestell, R., Lawrence, D., Backer, J. & Segall, J. E. (2001) Semin. Cancer Biol. 11, 119-128.
8. Jin, T., Zhang, N., Long, Y., Parent, C. A. & Devreotes, P. N. (2000) Science 287, 1034-1036.
9. Xiao, Z., Zhang, N., Murphy, D. B. & Devreotes, P. N. (1997) J. Cell Biol. 139, 365-374.
10. Servant, G., Weiner, O. D., Neptune, E. R., Sedat, J. W. & Bourne, H. R. (1999) Mol. Biol. Cell 10, 1163-1178.
11. Janetopoulos, C., Jin, T. & Devreotes, P. (2001) Science 291, 2408-2411.
12. Parent, C. A., Blacklock, B. J., Froehlich, W. M., Murphy, D. B. & Devreotes, P. N. (1998) Cell 95, 81-91.
13. Servant, G., Weiner, O. D., Herzmark, P., Balla, T., Sedat, J. W. & Bourne, H. R. (2000) Science 287, 1037-1040.
14. Iijima, M. & Devreotes, P. (2002) Cell 109, 599-610.
15. Funamoto, S., Meili, R., Lee, S., Parry, L. & Firtel, R. A. (2002) Cell 109, 611-623.
16. Meinhardt, H. (1999) J. Cell Sci. 112, 2867-2874.
17. Narang, A., Subramanian, K. K. & Lauffenburger, D. A. (2001) Ann. Biomed. Eng. 29, 677-691.
18. Postma, M. & Van Haastert, P. J. (2001) Biophys. J. 81, 1314-1323.
19. Rappel, W. J., Thomas, P. J., Levine, H. & Loomis, W. F. (2002) Biophys. J. 83, 1361-1367.
20. Devreotes, P. N. & Zigmond, S. H. (1988) Annu. Rev. Cell Biol. 4, 649-686.
21. Levchenko, A. & Iglesias, P. A. (2002) Biophys. J. 82, 50-63.
22. Iglesias, P. A. & Levchenko, A. (2002) Sci. STKE, RE12.
23. Sako, Y., Hibino, K., Miyauchi, T., Myamoto, Y., Ueda, M. & Yanagida, T. (2000) Single Mol. 1, 159-163.
24. Huang, Y. E., Iijima, M., Parent, C. A., Funamoto, S., Firtel, R. A. & Devreotes, P. (2003) Mol. Biol. Cell 14, 1913-1922.
25. Segall, J. E. (1993) Proc. Natl. Acad. Sci. USA 90, 8332-8336.
26. Weiner, O. D., Neilsen, P. O., Prestwich, G. D., Kirschner, M. W., Cantley, L. C. & Bourne, H. R. (2002) Nat. Cell Biol. 4, 509-513.
27. Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G. & Bourne, H. R. (2002) Nat. Cell Biol. 4, 513-518.
28. Zigmond, S. H. (1977) J. Cell Biol. 75, 606-616.
29. Fisher, P. R., Merkl, R. & Gerisch, G. (1989) J. Cell Biol. 108, 973-984.
30. Devreotes, P. & Janetopoulos, C. (2003) J. Biol. Chem. 278, 20445-20448.
31. Krishnan, J. & Iglesias, P. A. (2004.) J. Theor. Biol. 229, 85-99.
32. Kutscher, B., Devreotes, P. & Iglesias, P. A. (2004) Sci. STKE, p13.