Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death

Journal of Cell Science

Volumn 120, Issue 13, 2007, Pages 2259-2271

  Lee, Jong Hee ^a   Kim, Hea Sook ^a   Lee, Sung Jin ^a   Kim, Kyong Tai ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Acetylation; Cdk5; Neuronal apoptosis; p53; Phosphorylation; Ubiquitylation

Indexed keywords

CYCLIN DEPENDENT KINASE 5; MITOMYCIN C; NITROPRUSSIDE SODIUM; PROTEIN MDM2; PROTEIN P300; PROTEIN P53; SERINE;

ACETYLATION; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL; NERVE CELL DEGENERATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSCRIPTION INITIATION; UBIQUITINATION;

ACETYLATION; ACTIVE TRANSPORT, CELL NUCLEUS; APOPTOSIS; CELL LINE, TUMOR; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE 5; DNA DAMAGE; DOWN-REGULATION; E1A-ASSOCIATED P300 PROTEIN; HUMANS; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN;

EID: 34447498931     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.03468     Document Type: Article

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