Induction of lacZ mutations in Muta™Mouse primary hepatocytes

Environmental and Molecular Mutagenesis

Volumn 51, Issue 4, 2010, Pages 330-337

  Chen, Guosheng ^a   Gingerich, John ^a   Soper, Lynda ^a   Douglas, George R ^a   White, Paul A ^a  

^a HEALTH CANADA   (Canada)

Author keywords

Muta Mouse; Mutation; Primary hepatocytes

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 3 NITROBENZANTHRONE; BENZO[A]PYRENE; BETA GALACTOSIDASE; CIGARETTE SMOKE CONDENSATE; 2 AMINO 1 METHYL 6 PHENYL 1H IMIDAZO(4,5 B)PYRIDINE; 2-AMINO-1-METHYL-6-PHENYL-1H-IMIDAZO(4,5-B)PYRIDINE; AMINOPYRIDINE DERIVATIVE; CYTOCHROME P450; IMIDAZOLE DERIVATIVE; MUTAGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; GENE FREQUENCY; IN VITRO STUDY; LIVER CELL; METABOLIC ACTIVATION; MOUSE; MUTATION; NONHUMAN; PERFUSION; TRANSGENIC MOUSE; ANIMAL; CELL CULTURE; DRUG EFFECT; LACTOSE OPERON; METABOLISM; METHODOLOGY; MOUSE MUTANT; MUTAGEN TESTING; PATHOLOGY;

AMINOPYRIDINES; ANIMALS; BENZO(A)PYRENE; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; HEPATOCYTES; IMIDAZOLES; LAC OPERON; MICE; MICE, MUTANT STRAINS; MUTAGENICITY TESTS; MUTAGENS; MUTATION;

EID: 77951624082     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20540     Document Type: Article

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