Global transcriptional characterization of a mouse pulmonary epithelial cell line for use in genetic toxicology

Toxicology in Vitro

Volumn 23, Issue 5, 2009, Pages 816-833

  Berndt Weis, M Lynn ^a   Kauri, Lisa M ^a   Williams, Andrew ^a   White, Paul ^a   Douglas, George ^a   Yauk, Carole ^a  

^a HEALTH CANADA   (Canada)

Author keywords

Benzo(a)pyrene; Epithelial cells; In vitro characterization; In vivo versus in vitro; Lung; Microarray; Mutagenicity; Real time PCR; Transgenic

Indexed keywords

BENZO[A]PYRENE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL METABOLISM; CONTROLLED STUDY; DNA REPAIR; ENZYME INDUCTION; GENE EXPRESSION PROFILING; GENETIC TOXICOLOGY; GENETIC TRANSCRIPTION; IN VIVO STUDY; ISOLATED LUNG; LUNG ALVEOLUS CELL; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS CELL TYPE 2; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; UNINDEXED SEQUENCE;

ANIMALS; BENZO(A)PYRENE; CELL LINE; ENZYME INDUCTION; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LUNG; MALE; MICE; MICE, TRANSGENIC; MUTAGENESIS; MUTAGENS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PULMONARY ALVEOLI; TIME FACTORS;

EID: 67649381676     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.04.008     Document Type: Article

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