Tissue-specific metabolic activation and mutagenicity of 3-nitrobenzanthrone in Muta™Mouse

Environmental and Molecular Mutagenesis

Volumn 49, Issue 8, 2008, Pages 602-613

  Chen, Guosheng ^a   Gingerich, John ^a   Soper, Lynda ^a   Douglas, George R ^a   White, Paul A ^a  

^a HEALTH CANADA   (Canada)

Author keywords

Acetyltransferase; Diesel exhaust; Nitroarene; Nitroreductase

Indexed keywords

1 NITROPYRENE REDUCTASE; 3 NITROBENZANTHRONE; 3 NITROBENZANTHRONE REDUCTASE; ACYLTRANSFERASE; BETA GALACTOSIDASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER; BONE MARROW; COLON; COLON MUCOSA; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA ADDUCT; ENZYME ACTIVITY; GENE FREQUENCY; GENE LOCUS; INTESTINE EPITHELIUM; LIVER; LUNG; METABOLISM; MOUSE; MUTAGENICITY; NONHUMAN; SALMONELLA; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ACETYLTRANSFERASES; ANIMALS; BENZ(A)ANTHRACENES; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, MUTANT STRAINS; MUTAGENICITY TESTS; MUTAGENS; NITROREDUCTASES; SUBSTRATE SPECIFICITY;

SALMONELLA;

EID: 54249168312     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20410     Document Type: Article

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