In vitro antifungal activity of polyfunctionalized 2-(hetero)arylquinolines prepared through imino Diels-Alder reactions

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 17, 2008, Pages 7908-7920

  Meléndez Gómez, Carlos M ^a   Kouznetsov, Vladimir V ^a   Sortino, Maximiliano A ^b   Álvarez, Sandra L ^b   Zacchino, Susana A ^b  

^a UNIVERSIDAD INDUSTRIAL DE SANTANDER   (Colombia)

^b UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

Antifungal properties; Lewis acid catalyzed imino Diels Alder reactions; Polyfunctionalized quinolines; Synthesis

Indexed keywords

4 AMINOPYRIDINE; 4 METHYL 2 PHENYLQUINOLINE; 6 BROMO 4 METHYL 2 (BETA PYRIDYL)QUINOLINE; AMPHOTERICIN B; KETOCONAZOLE; LEWIS ACID; POLYFUNCTIONAL GROUP; QUINOLINE DERIVATIVE; TERBINAFINE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DERMATOPHYTE; DIELS ALDER REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; LIPOPHILICITY; NONHUMAN; SACCHAROMYCES CEREVISIAE; TRICHOPHYTON;

ACIDS; ANTIFUNGAL AGENTS; ARTHRODERMATACEAE; CANDIDA; CATALYSIS; CRYPTOCOCCUS; DOSE-RESPONSE RELATIONSHIP, DRUG; IMINES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; QUINOLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

ALNUS; ARTHRODERMATACEAE; FUNGI;

EID: 50349098409     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.079     Document Type: Article

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