Synthesis and biological properties of new 5-nitroindazole derivatives

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 9, 2005, Pages 3197-3207

  Arán, Vicente J ^a   Ochoa, Carmen ^a   Boiani, Lucía ^b   Buccino, Pablo ^b   Cerecetto, Hugo ^b   Gerpe, Alejandra ^b   González, Mercedes ^b   Montero, David ^c   Nogal, Juan José ^c   Gómez Barrio, Alicia ^c   Azqueta, Amaya ^d   López De Ceráin, Adela ^d   Piro, Oscar E ^e   Castellano, Eduardo E ^f  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d UNIVERSITY OF NAVARRA   (Spain)

^e FACULTAD DE CIENCIAS EXACTAS   (Argentina)

^f UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

5 Nitroindazoles; Antiprotozoal and antineoplastic activities; QSAR; Synthesis

Indexed keywords

INDAZOLE DERIVATIVE; N [2 [(3 HYDROXY 5 NITRO 1H INDAZOL 1 YL)METHYL]BENZYL]PIPERIDINE; N [5 (3 BENZYLOXY 5 NITRO 1H INDAZOL 1 YL)PENTYL]PIPERIDINE; N [5 (3 METHOXY 5 NITRO 1H INDAZOL 1 YL) 3 OXAPENTYL]PIPERIDINE; N [5 (3 METHOXY 5 NITRO 1H INDAZOL 1 YL)PENTYL]PIPERIDINE; N,N DIMETHYL 5 (3 BENZYLOXY 5 NITRO 1H INDAZOL 1 YL) 3 OXAPENTYLAMINE; N,N DIMETHYL 5 (3 BENZYLOXY 5 NITRO 1H INDAZOL 1 YL)PENTYLAMINE; N,N DIMETHYL 5 (3 METHOXY 5 NITRO 1H INDAZOL 1 YL) 3 OXAPENTYLAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRICHOMONAS VAGINALIS; X RAY CRYSTALLOGRAPHY;

EID: 20144386871     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.02.043     Document Type: Article

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