Antioxidants in treating pathologies involving oxidative damage: An update on medicinal chemistry and biological activity of stobadine and related pyridoindoles

Current Medicinal Chemistry

Volumn 17, Issue 6, 2010, Pages 552-570

  Juranek, I ^a   Horakova, L ^a   Rackova, L ^a   Stefek, M ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

Author keywords

Free radical diseases; Oxidative stress; Reactive oxygen species; Stobadine; Substituted pyridoindoles; Synthetic scavengers and antioxidants

Indexed keywords

21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CARBOLINE DERIVATIVE; DEHYDROSTOBADINE; MELATONIN; METHYLPREDNISOLONE; N TERT BUTYL ALPHA PHENYLNITRONE; REACTIVE OXYGEN METABOLITE; SEROTONIN; STOBADINE; TROLOX C; UNCLASSIFIED DRUG; ZOPOLRESTAT;

ALBUMINURIA; BIOLOGICAL ACTIVITY; BRAIN EDEMA; BRAIN ISCHEMIA; CARDIOMYOPATHY; CATARACT; CHRONIC INFLAMMATION; DEGENERATIVE DISEASE; DIABETES MELLITUS; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG EFFICACY; DRUG SAFETY; HEART INFARCTION; HEART PROTECTION; HUMAN; HYPOXIA; IC 50; ISCHEMIA; KIDNEY DYSFUNCTION; LIPID PEROXIDATION; LIPOPHILICITY; LIVER PROTECTION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEINURIA; RENAL PROTECTION; REVIEW; SINGLE DRUG DOSE; STROKE; STRUCTURE ACTIVITY RELATION;

ALDEHYDE REDUCTASE; ANIMALS; ANTIOXIDANTS; CARBOLINES; DIABETES MELLITUS, EXPERIMENTAL; INDOLES; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 77950662469     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710790416317     Document Type: Review

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