In vitro inhibition of lens aldose reductase by (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]Indole-8-yl)-acetic acid in enzyme preparations isolated from diabetic rats

General Physiology and Biophysics

Volumn 25, Issue 4, 2006, Pages 415-425

  Djoubissie, P O ^a   Snirc, V ^a   Sotnikova, R ^a   Zurova, J ^a   Kyselova, Z ^a   Skalska, S ^a   Gajdosik, A ^a   Javorkova, V ^b   Vlkovicova, J ^b   Vrbjar, N ^b   Stefek, Milan ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Aldose reductase inhibition; Diabetic complications; Experimental diabetes; Polyol pathway

Indexed keywords

(2 BENZYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE 8 YL)ACETIC ACID; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; GLYCERALDEHYDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DETERMINATION; DRUG EFFICACY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME KINETICS; FEMALE; IC 50; IN VITRO STUDY; KIDNEY; LENS; NONHUMAN; RAT; SEQUENCE HOMOLOGY; STREPTOZOCIN DIABETES;

ACETIC ACIDS; ALDEHYDE REDUCTASE; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; INDOLES; KIDNEY; LENS, CRYSTALLINE; MALE; RATS; RATS, WISTAR; STREPTOZOCIN;

ANIMALIA; RATTUS;

EID: 33947257808     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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