Stobadine protects rat kidney against ischaemia/reperfusion injury

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 3, 2007, Pages 210-216

  Guz, Galip ^a,d   Demirogullari, Billur ^a   Ulusu, Nuray N ^b   Dogu, Cihangir ^a   Demirtola, Arzu ^a   Kavutcu, Mustafa ^a   Omeroglu, Suna ^a   Stefek, Milan ^c   Karasu, Cimen ^a  

^a GAZI UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

^c INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glutathione; Ischaemia; Kidney; Malondialdehyde; Reperfusion; Stobadine

Indexed keywords

CREATININE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALONALDEHYDE; PADGEM PROTEIN; PHOSPHOGLUCONATE DEHYDROGENASE; STOBADINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KIDNEY ARTERY STENOSIS; KIDNEY DYSFUNCTION; KIDNEY ISCHEMIA; MALE; MORPHOLOGY; NONHUMAN; RAT; RENAL PROTECTION; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE; UREA NITROGEN BLOOD LEVEL; WISTAR RAT;

ANIMALS; BLOOD UREA NITROGEN; CARBOLINES; CREATININE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; KIDNEY; KIDNEY DISEASES; MALE; MALONDIALDEHYDE; PENTOSE PHOSPHATE PATHWAY; PHOSPHOGLUCONATE DEHYDROGENASE; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 33846428762     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04574.x     Document Type: Article

References (37)

1. Abernethy VE, Liberthal W. Acute renal failure in the critical ill patient. Crit. Care Clin. 2002; 18: 203-22.
2. Bonventre JV, Zuk A. Ischemic acute renal failure: An inflammatory disease? Kidney Int. 2004; 66: 480-5.
3. Johnson KJ, Weinberg JM. Postischemic renal injury due to oxygen radicals. Curr. Opin. Nephrol. Hypertens. 1993; 2: 625-635.
4. Patel NS, Sharples EJ, Cuzzocrea S et al. Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int. 2004; 66: 983-9.
5. Scaduto Jr RC, Gattone VH, Grotyohann LW, Wertz J, Martin LF. Effect of an altered glutathione content on renal ischemic injury. Am. J. Physiol. 1988; 255: F911-21.
6. Ulusu NN, Ozbey G, Tandogan B et al. Circadian variations in the activities of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in the liver of control and streptozotocin-induced diabetic rats. Chronobiol. Int. 2005; 22: 667-77.
7. Erbas H, Aydogdu N, Kaymak K. Effects of N-acetylcysteine on arginase, ornithine and nitric oxide in renal ischemia-reperfusion injury. Pharmacol. Res. 2004; 50: 523-7.
8. Singh D, Chander V, Chopra K. Protective effect of catechin on ischemia-reperfusion-induced renal injury in rats. Pharmacol. Rep. 2005; 57: 70-6.
9. Horakova L, Stolc S. Antioxidant and pharmacodynamic effects of pyridoindole stobadine. Gen. Pharmacol. 1998; 30: 627-38.
10. Stefek M, Gajdosik A, Tribulova N et al. The pyridoindole antioxidant stobadine attenuates albuminuria, enzymuria, kidney lipid peroxidation and matrix collagen cross-linking in streptozotocin-induced diabetic rats. Methods. Find. Exp. Clin. Pharmacol. 2002; 24: 565-71.
11. Stefek M, Tribulova N, Gajdosik A, Gajdosikova A. The pyridoindole antioxidant stobadine attenuates histochemical changes in kidney of streptozotocin-induced diabetic rats. Acta Histochem. 2002; 104: 413-17.
12. Ulusu NN, Sahilli M, Avci A et al. Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: Effects of stobadine and vitamin E. Neurochem. Res. 2003; 28: 815-23.
13. Sotnikova R, Okruhlicova L, Noskovic P. Endothelial protective effect of stobadine on ischaemia/reperfusion-induced injury. Gen. Physiol. Biophys. 1998; 17: 253-64.
14. Bartosikova L, Necas J, Benes L et al. Influence of antioxidant effect of stobadine derivative in condition of kidney ischemia-reperfusion in a pre-clinical experiment (effect in therapy). Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech. Repub. 2005; 149: 377-80.
15. Necas J, Bartosikova L, Benes L et al. Influence of antioxidant effect of stobadine derivative in condition of kidney ischemia-reperfusion in a pre-clinical experiment (effect in prophylaxis). Biomed. Pap. Med. Fac. University Palacky Olomouc Czech. Repub. 2005; 149: 385-8.
16. Aykac G, Uysal M, Yalcin AS, Kocak-Toker N, Sivas A, Oz H. The effect of chronic ethanol ingestion on hepatic lipid peroxide, glutathione, glutathione peroxidase and glutathione transferase in rats. Toxicology 1985; 36: 71-6.
17. Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 1978; 86: 271-8.
18. Betke K, Brewer GJ, Kirkman HN et al. Standardized method for G-6-PD assay of haemolysates. WHO Tech. Rep. Ser. 1967; 366: 30-2.
19. Pearse BM, Rosemeyer MA. 6-Phosphogluconate dehydrogenase from human erythrocytes. Methods Enzymol. 1975; 41: 220-6.
20. Acan NL, Tezcan EF. Sheep brain glutathione reductase: Purification and general properties. FEBS Lett. 1989; 250: 72-4.
21. Beutler E. Red cell metabolism. In: A Manual of Biochemical Methods. Grone & Stratton, New York. 1971; 66-8.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248-54.
23. Horakova L, Sies H, Steenken S. Antioxidant action of stobadine. Methods Enzymol. 1994; 234: 572-80.
24. Ross D. Glutathione, free radicals and chemotherapeutic agents. Mechanisms of free-radical induced toxicity and glutathione-dependent protection. Pharmacol. Ther. 1988; 37: 231-49.
25. Barnard ML, Snyder SJ, Engerson TD, Turrens JF. Antioxidant enzyme status of ischemic and postischemic liver and ischemic kidney in rats. Free Radic. Biol. Med. 1993; 15: 227-32.
26. Seth P, Kumari R, Madhavan S et al. Prevention of renal ischemia-reperfusion-induced injury in rats by picroliv. Biochem. Pharmacol. 2000; 59: 1315-22.
27. 2 in aorta isolated from chronically streptozotocin-diabetic rats: Effects of antioxidant enzymes and enzymes inhibitors. Free Radic. Biol. Med. 1999; 27: 16-27.
28. Volkovova K, Chorvathova V, Jurcovicova M, Koszeghyova L, Bobek P. Antioxidative state of the myocardium and kidneys in acute diabetic rats. Physiol. Res. 1993; 42: 251-5.
29. Hunkar T, Aktan F, Ceylan A, Karasu C. Effects of cod liver oil on tissue antioxidant pathways in normal and streptozotocin-diabetic rats. Cell Biochem. Funct. 2002; 20: 297-302.
30. Mak DH, Ip SP, Li PC, Poon MK, Ko KM. Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats. Mol. Cell Biochem. 1996; 162: 153-8.
31. Abdel-Rahim EA, el Saadany SS, Abo-Eytta AM, Wasif MM. The effect of sammo administration on some fundamental enzymes of pentose phosphate pathway and energy metabolites of alloxanized rats. Nahrung 1992; 36: 8-14.
32. Ulusu NN, Tandogan B. Purification and kinetics of sheep kidney cortex glucose-6-phosphate dehydrogenase. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 2006; 143: 249-55.
33. Khundmiri SJ, Asghar M, Khan F, Salim S, Yusufi AN. Effect of ischemia and reperfusion on enzymes of carbohydrate metabolism in rat kidney. J. Nephrol. 2004; 17: 377-83.
34. 2+-ATPase activity in heart and liver of streptozotocin-diabetic rats: Comparison with vitamin E. Biochim. Biophys. Acta 2002; 1588: 71-8.
35. Koo DD, Welsh KI, Roake JA, Morris PJ, Fuggle SV. Ischemia/reperfusion injury in human kidney transplantation: An immunohistochemical analysis of changes after reperfusion. Am. J. Pathol .1998; 153: 557-66.
36. Stambe C, Atkins RC, Tesch GH et al. Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis. J. Am. Soc. Nephrol. 2003; 14: 338-51.
37. Zizzi HC, Zibari GB, Granger DN et al. Quantification of P-selectin expression after renal ischemia and reperfusion. J. Pediatr. Surg. 1997; 32: 1010-13.