Temporal relationship between lens protein oxidation and cataract development in streptozotocin-induced diabetic rats

Physiological Research

Volumn 54, Issue 1, 2005, Pages 49-56

  Kyselova Z ^a   Garcia, S J ^b   Gajdosikova A ^a   Gajdosik A ^a   Stefek M ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cataract; Protein carbonyls; Protein oxidation; Protein sulfhydryls; STZ diabetes

Indexed keywords

CARBONYL DERIVATIVE; LENS PROTEIN; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATARACT; CONTROLLED STUDY; DIABETES MELLITUS; INCIDENCE; MALE; NONHUMAN; OXIDATION; PROTEIN CONTENT; QUANTITATIVE ANALYSIS; RAT; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CATARACT; CRYSTALLINS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE PROGRESSION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYPERGLYCEMIA; MALE; MOLECULAR WEIGHT; OXIDATION-REDUCTION; RATS; RATS, WISTAR; SULFHYDRYL COMPOUNDS;

EID: 14944361890     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. AGARDH E, HULTBERG B, AGARDH CD: Effect of inhibition of glycation and oxidative stress on the development of cataract and retinal vessel abnormalities in diabetic rats. Curr Eye Res 21: 543-549, 2000.
2. ALTOMARE E, VENDEMIALE G, GRATTAGLIANO L, ANGELINI P, MICELLI-FERRARI T, CARDIA L: Human diabetic cataract: role of lipid peroxidation. Diabetes Metab 21: 173-179, 1996.
3. ALTOMARE E, GRATTAGLIANO I, VENDEMIALE G, MICELLI-FERRARI T, SIGNORILE A, CARDIA L: Oxidative protein damage in human diabetic eye: evidence for a retinal participation. Eur J Clin Invest 27: 141-147, 1997.
4. ANSARI NH, SRIVASTAVA SK: Allopurinol promotes and butylated hydroxytoluene prevents sugar-induced cataractogenesis. Biochem Biophys Res Commun 168: 939-943, 1990.
5. ARGIROVA MD, BREIPOHL W: Comparison between modifications of lens proteins resulted from glycation with methylglyoxal, glyoxal, ascorbic acid, and fructose. J Biochem Mol Toxicol 16: 140-145, 2002.
6. BAYNES JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412, 1991.
7. BAYNES JW, THORPE SR: Perspectives in diabetes. Role of oxidative stress in diabetic complications. A new perspective and old paradigm. Diabetes 48: 1-9, 1999.
8. BESWICK HT, HARDING JJ: Conformational changes induced in lens α- and β-crystallins by modification with glucose 6-phosphate. Biochem J 246: 761-769, 1987.
9. BHUYAN KC, BHUYAN KD: Molecular mechanisms of cataractogenesis. III. Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract. Curr Eye Res 3: 67-81, 1984.
10. BOSCIA F, GRATTAGLIANO I, VENDEMIALE G, MICELLI-FERRARI T, ALTOMARE E: Protein oxidation and lens opacity in humans. Invest Opthalmol Vis Sci 41: 2461-2465, 2000.
11. BRON AJ, BROWN NAP, HARDING JJ, GANEA E: The lens and cataract in diabetes. Int Ophthalmol Clin 38: 37-67, 1998.
12. BROWNLEE M: Advanced glycation end products in diabetes and ageing. Annu Rev Med 46: 223-234, 1996.
13. CHEVION M, BERENSHTEIN E, STADTMAN ER: Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res 33: 99-108, 2000.
14. DUHAIMAN AS: Glycation of human lens proteins from diabetic and (nondiabetic) senile cataract patients. Glycoconj J 12: 618-621, 1995.
15. FOLLANSBEE MH, BEYER KH, VESSEL ES: Studies on pyrazinoylguanidine. 6. Prevention of cataracts in STZ-diabetic rats. Pharmacology 54: 256-260, 1997.
16. HOCKWIN O, KOJIMA M, MULLER-BREITENKAMP U, WEGENER AL: Lens and cataract research of the 20th century: a review of results, errors and misunderstandings. Dev Ophthalmol 35: 1-11, 2002.
17. HUM TP, AUGUSTEYN RC: The state of sulphydryl groups in proteins isolated from normal and cataractous human lenses. Curr Eye Res 6: 1091-1101, 1987.
18. JAHNGEN-HODGE J, TAYLOR A, SHANG F, HUANG LL, MURA C: Oxidative stress to lens crystallins. Methods Enzymol 233: 512-522, 1994.
19. KUBO E, MIYOSHI N, FUKUDA M, AKAGI Y: Cataract formation through the polyol pathway is associated with free radical production. Exp Eye Res 68: 457-464, 1999.
20. LAEMMLI UK: Cleavage of structural proteins during the assembly of the head of bacteriophage. Nature 227: 680-685, 1970.
21. LEVINE RL, GARLAND D, OLIVER CN, AMICI A, CLIMENT I, LENZ AG, AHN BW, SHALTIEL S, STADTMAN ER: Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 186: 464-478, 1990.
22. LIGGINS J, FURTH AJ: Role of protein-bound carbonyl groups in the formation of advanced glycation end-products. Biochem Biophys Acta 1361: 123-130, 1997.
23. LINKLATER HA, DZIALOSZYNSKI T, MCLEOD HL, SANFORD SE, TREVITHICK JR: Modeling cortical cataractogenesis. XI. Vitamin C reduces α-crystallin leakage from lenses in diabetic rats. Exp Eye Res 51: 241-247, 1990.
24. LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ: Protein measurement with Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
25. MONNIER VM, STEVENS VJ, CERAMI A: Nonenzymatic glycosylation, sulfhydryl oxidation, and aggregation of lens proteins in experimental sugar cataracts. J Exp Med 150: 1098-1107, 1979.
26. OHTA Y, YAMASAKI T, NIWA T, MAJIMA Y, ISHIGURO I: Preventive effect of topical vitamin-E containing liposome instillation on the progression of galactose cataract. Comparison between 5-week and 12-week old rats fed a 25% galactose diet. Exp Eye Res 68: 747-755, 1999.
27. PACKER L, KRAEMER K, RIMBACH G: Molecular aspects of lipoic acid in the prevention of diabetic complications. Nutrition 17: 888-895, 2001.
28. PERRY RE, SWAMY MS, ABRAHAM EC: Progressive changes in lens crystallin glycation and high-molecular-weight aggregate formation leading to cataract development in streptozotocin-diabetic rats. Exp Eye Res 44: 269-282, 1987.
29. REZNICK AZ, PACKER L: Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 223: 357-363, 1994.
30. ROSS WM, CREIGHTON MO, STEWART-DEHAAN PJ, SANWAL M, HIRST M, TREVITHICK JR: Modeling cortical cataractogenesis. III. Effect of vitamin E on cataractogenesis in diabetic rats. Can J Ophthalmol 17: 616-6, 1982.
31. SPECTOR A: Review: oxidative stress and disease. J Ocul Pharmacol Ther 16: 193-201, 2000.
32. STADTMAN ER, BERLETT BS: Reactive oxygen-mediated protein oxidation in aging and disease. Chem Res Toxicol 10: 485-494, 1997.
33. ŠTEFEK M, TRNKOVÁ Z, KRIŽANOVÁ L: 2,4-Dinitrophenylhydrazine carbonyl assay in metal-catalysed protein glycoxidation. Redox Rep 4: 43-48, 1999.
34. STITT AV: Advanced glycation: an important pathological event in diabetic and age related disease. Br J Ophthalmol 85: 746-753, 2001.
35. SWAMY MS, ABRAHAM EC: Lens protein composition, glycation and high molecular weight aggregation in aging rats. Invest Ophthalmol Vis Sci 28: 1693-1701, 1987.
36. TAKEMOTO LJ: Oxidation of cysteine residues from alpha-A crystallin during cataractogenesis of the human lens. Biochem Biophys Res Commun 223: 216-220, 1996.
37. TAKEMOTO LJ: Beta A3/A1 crystallin from human cataractous lens contains an intramolecular disulfide bond. Curr Eye Res 16: 719-724, 1997.
38. TRUSCOTT RJW, AUGUSTEYN RC: The state of sulphydryl groups in normal and cataractous human lenses. Exp Eye Res 25: 139-148, 1977.
39. VARMA SD: Scientific basis for medical therapy of cataracts by antioxidants. Am Clin Nutr 53: 335-345, 1991.
40. VENDEMIALE G, GRATTAGLIANO I, MICELLI-FERRARI T, CARDIA L, ALTOMARE E: Abnormal protein redox status in the lens and vitreous of diabetic subjects. Diabetologia 9: 1239-1240, 1996.
41. VENDEMIALE G, GRATTAGLIANO I, ALTOMARE E: An update on the role of free radicals and antioxidant defense in human disease. Int J Clin Lab Res 29: 49-55, 1999.