Stobadine-modulated human neutrophil functional responsiveness: Effect on particular and soluble stimulation

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 26, Issue 6, 2004, Pages 395-398

  Pecivova J ^a,b   Macickova T ^a   Nosal' R ^a   Fabryova V ^a  

^a UNIVERSITY HOSPITAL BRATISLAVA   (Slovakia)

^b INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

Author keywords

Human Neutrophils; Myeloperoxidase; Respiratory Burst; Stobadine; Superoxide

Indexed keywords

CALCIMYCIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FREE RADICAL; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; STOBADINE; SUPEROXIDE DISMUTASE; WORTMANNIN; ZYMOSAN;

ARTICLE; CELL FUNCTION; DEGRANULATION; DOSE RESPONSE; ENZYME RELEASE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; NEUTROPHIL; NORMAL HUMAN; OPSONIZATION; RESPIRATORY BURST;

CARBOLINES; CELL DEGRANULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; HUMANS; NEUTROPHILS; RESPIRATORY BURST; SOLUBILITY; SUPEROXIDES;

EID: 4043145759     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Heinecke, J.W. Tyrosyl radical production by myeloperoxidase: A phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins. Toxicology 2002, 177: 11-22.
2. Klebanoff, S.J. Myeloperoxidase. Proc Assoc Am Physicians 1999, 111: 383-9.
3. Reinhold, S.L., Prescott, S.M., Zimmerman,G.A., McIntyre, T.M. Activation of human neutrophil phospholipase D by three separable mechanisms. FASEBJ 1990, 4: 208-14.
4. Horáková, E., Štolc, S. Antioxidant and pharmacodynamic effects of pyridoindole stobadine. Gen Pharmac 1998, 30: 627-38.
5. Drábiková, K., Pečivová, J., Mačičková, T., Kotuliaková, K., Nosál', R., Danihelová, E. Effect of stobadine on human stimulated polymorphonuclear leukocytes. Methods Find Exp Clin Pharmacol 1999, 21: 75-8.
6. Lojek, A., Kubala, L., Čížová, H., Číž, M. A comparison of whole blood neutrophil chemiluminescence measured with cuvette and microtitre luminometers. Luminescence 2002, 17: 1-4.
7. Somersalo, K., Salo, O.P., Bjorksten, F., Mustakalio, K.K. A simplified Boyden chamber assay for neutrophil chemotaxis based on quantitation of myeloperoxidase. Anal Biochem 1990, 185: 238-42.
8. Malech, L.H., Gallin, J.I. Neutrophils in human diseases. New Engl J Med 1987, 317: 687-94.
9. Burnham, D.N, Tyagi, S.R., Uhlinger, D.J., Lambeth, J.D. Diacylglycerol generation and phosphoinositide turnover in human neutrophils: Effects of particulate versus soluble stimuli. Arch Biochem Biophys 1989, 269: 345-53.
10. Pečivová, J., Mačičková, T, Nosál', R., Danihelová, E. Effect of stobadine on superoxide generation and degranulation of stimulated human polymorphonuclear leukocytes in vitro. Biologia 2000, 55: 103-6.
11. Pečivová, J., Mačičková, T., Číč, M., Nosál', R., Lojek, A. Effect of stobadine on zymosan stimulated generation of reactive oxygen species in human blood cells. Physiol Res 2004, 53: 97-102.
12. Heilmann, J., Merfort, I., Weiss, M. Radical scavenger activity of different 3′,4′-dihydroxyflavonols and 1,5-dicaffeoylquinic acid studied by inhibition of chemiluminescence. Planta Med, 1995, 61: 435-8.
13. 2+ influx channels in leukocytes: A therapeutic target? TRENDS Pharmacol Sci 2002, 23: 63-70.
14. Jančinová, V., Nosál', R., Danihelová, E. Aggregation of human blood platelets in the presence of the pyridoindole stobadine. Life Sci 1999, 65: 1983-6.
15. Pečivová, J., Drábiková, K., Kotuliaková, K., Mačičková, T., Nosál', R., Danihelová, E. Effect of stobadine on oxygen free radical generation in stimulated human polymorphonuclear leukocytes. Life Sci 1999, 65: 1987-9.