Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: A mechanism for aneuploidy in cancer

Experimental and Molecular Pathology

Volumn 88, Issue 2, 2010, Pages 225-233

  Liu, Qingdu ^a   Hirohashi, Yoshihiko ^a,b   Du, Xiulian ^a   Greene, Mark I ^a   Wang, Qiang ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cdc20; Centrosome; Kinetochore; Mad2; Mitosis; Nek2

Indexed keywords

CELL CYCLE PROTEIN 20; NEK2 PROTEIN; PROTEIN MAD2; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANEUPLOIDY; ARTICLE; CELLULAR DISTRIBUTION; CENTROSOME; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MITOSIS INHIBITION; NEOPLASM; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SPINDLE POLE BODY;

ANEUPLOIDY; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; GENE DUPLICATION; HUMANS; MITOSIS; MITOTIC SPINDLE APPARATUS; NEOPLASMS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; SEQUENCE DELETION;

EID: 77950627939     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2009.12.004     Document Type: Article

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