-
1
-
-
1842486792
-
The spindle checkpoint, aneuploidy, and cancer
-
Bharadwaj R., Yu H. The spindle checkpoint, aneuploidy, and cancer. Oncogene. 23:2004;2016-2027
-
(2004)
Oncogene
, vol.23
, pp. 2016-2027
-
-
Bharadwaj, R.1
Yu, H.2
-
2
-
-
0034214405
-
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function
-
Brady D.M., Hardwick K.G. Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr. Biol. 10:2000;675-678
-
(2000)
Curr. Biol.
, vol.10
, pp. 675-678
-
-
Brady, D.M.1
Hardwick, K.G.2
-
3
-
-
0036322225
-
BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
-
Chen R.H. BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1. J. Cell Biol. 158:2002;487-496
-
(2002)
J. Cell Biol.
, vol.158
, pp. 487-496
-
-
Chen, R.H.1
-
4
-
-
4143069361
-
Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint
-
Chen R.H. Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint. EMBO J. 23:2004;3113-3121
-
(2004)
EMBO J.
, vol.23
, pp. 3113-3121
-
-
Chen, R.H.1
-
5
-
-
0042696987
-
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint
-
Chung E., Chen R.H. Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint. Nat. Cell Biol. 5:2003;748-753
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 748-753
-
-
Chung, E.1
Chen, R.H.2
-
6
-
-
0142123285
-
The spindle checkpoint requires cyclin-dependent kinase activity
-
D'Angiolella V., Mari C., Nocera D., Rametti L., Grieco D. The spindle checkpoint requires cyclin-dependent kinase activity. Genes Dev. 17:2003;2520-2525
-
(2003)
Genes Dev.
, vol.17
, pp. 2520-2525
-
-
D'Angiolella, V.1
Mari, C.2
Nocera, D.3
Rametti, L.4
Grieco, D.5
-
7
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
8
-
-
0036199862
-
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
-
Fang G. Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol. Biol. Cell. 13:2002;755-766
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 755-766
-
-
Fang, G.1
-
9
-
-
0032525783
-
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
-
a
-
Fang G., Yu H., Kirschner M.W. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev. 12:1998;1871-1883. a
-
(1998)
Genes Dev.
, vol.12
, pp. 1871-1883
-
-
Fang, G.1
Yu, H.2
Kirschner, M.W.3
-
10
-
-
0032133145
-
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
-
b
-
Fang G., Yu H., Kirschner M.W. Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol. Cell. 2:1998;163-171. b
-
(1998)
Mol. Cell
, vol.2
, pp. 163-171
-
-
Fang, G.1
Yu, H.2
Kirschner, M.W.3
-
11
-
-
0031893014
-
Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint
-
Farr K.A., Hoyt M.A. Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint. Mol. Cell. Biol. 18:1998;2738-2747
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2738-2747
-
-
Farr, K.A.1
Hoyt, M.A.2
-
12
-
-
0036713310
-
The anaphase-promoting complex: It's not just for mitosis any more
-
Harper J.W., Burton J.L., Solomon M.J. The anaphase-promoting complex. it's not just for mitosis any more Genes Dev. 16:2002;2179-2206
-
(2002)
Genes Dev.
, vol.16
, pp. 2179-2206
-
-
Harper, J.W.1
Burton, J.L.2
Solomon, M.J.3
-
13
-
-
0034683744
-
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
-
Howell B.J., Hoffman D.B., Fang G., Murray A.W., Salmon E.D. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells. J. Cell Biol. 150:2000;1233-1250
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1233-1250
-
-
Howell, B.J.1
Hoffman, D.B.2
Fang, G.3
Murray, A.W.4
Salmon, E.D.5
-
14
-
-
0033598127
-
Regulation of APC activity by phosphorylation and regulatory factors
-
Kotani S., Tanaka H., Yasuda H., Todokoro K. Regulation of APC activity by phosphorylation and regulatory factors. J. Cell Biol. 146:1999;791-800
-
(1999)
J. Cell Biol.
, vol.146
, pp. 791-800
-
-
Kotani, S.1
Tanaka, H.2
Yasuda, H.3
Todokoro, K.4
-
15
-
-
0346363801
-
Mitotic regulation of the human anaphase-promoting complex by phosphorylation
-
Kraft C., Herzog F., Gieffers C., Mechtler K., Hagting A., Pines J., Peters J.M. Mitotic regulation of the human anaphase-promoting complex by phosphorylation. EMBO J. 22:2003;6598-6609
-
(2003)
EMBO J.
, vol.22
, pp. 6598-6609
-
-
Kraft, C.1
Herzog, F.2
Gieffers, C.3
Mechtler, K.4
Hagting, A.5
Pines, J.6
Peters, J.M.7
-
16
-
-
0034025648
-
Mitotic regulation of the APC activator proteins CDC20 and CDH1
-
Kramer E.R., Scheuringer N., Podtelejnikov A.V., Mann M., Peters J.M. Mitotic regulation of the APC activator proteins CDC20 and CDH1. Mol. Biol. Cell. 11:2000;1555-1569
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 1555-1569
-
-
Kramer, E.R.1
Scheuringer, N.2
Podtelejnikov, A.V.3
Mann, M.4
Peters, J.M.5
-
17
-
-
0343986407
-
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
-
Luo X., Fang G., Coldiron M., Lin Y., Yu H., Kirschner M.W., Wagner G. Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat. Struct. Biol. 7:2000;224-229
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 224-229
-
-
Luo, X.1
Fang, G.2
Coldiron, M.3
Lin, Y.4
Yu, H.5
Kirschner, M.W.6
Wagner, G.7
-
18
-
-
0036161468
-
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
-
Luo X., Tang Z., Rizo J., Yu H. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol. Cell. 9:2002;59-71
-
(2002)
Mol. Cell
, vol.9
, pp. 59-71
-
-
Luo, X.1
Tang, Z.2
Rizo, J.3
Yu, H.4
-
19
-
-
1842420626
-
The Mad2 spindle checkpoint protein has two distinct natively folded states
-
Luo X., Tang Z., Xia G., Wassmann K., Matsumoto T., Rizo J., Yu H. The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat. Struct. Mol. Biol. 11:2004;338-345
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 338-345
-
-
Luo, X.1
Tang, Z.2
Xia, G.3
Wassmann, K.4
Matsumoto, T.5
Rizo, J.6
Yu, H.7
-
20
-
-
0036789555
-
The spindle checkpoint: Structural insights into dynamic signalling
-
Musacchio A., Hardwick K.G. The spindle checkpoint. structural insights into dynamic signalling Nat. Rev. Mol. Cell Biol. 3:2002;731-741
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 731-741
-
-
Musacchio, A.1
Hardwick, K.G.2
-
21
-
-
0037178719
-
Segregating sister genomes: The molecular biology of chromosome separation
-
Nasmyth K. Segregating sister genomes. the molecular biology of chromosome separation Science. 297:2002;559-565
-
(2002)
Science
, vol.297
, pp. 559-565
-
-
Nasmyth, K.1
-
22
-
-
0034717297
-
Splitting the chromosome: Cutting the ties that bind sister chromatids
-
Nasmyth K., Peters J.M., Uhlmann F. Splitting the chromosome. cutting the ties that bind sister chromatids Science. 288:2000;1379-1385
-
(2000)
Science
, vol.288
, pp. 1379-1385
-
-
Nasmyth, K.1
Peters, J.M.2
Uhlmann, F.3
-
23
-
-
14444267778
-
How cells get the right chromosomes
-
Nicklas R.B. How cells get the right chromosomes. Science. 275:1997;632-637
-
(1997)
Science
, vol.275
, pp. 632-637
-
-
Nicklas, R.B.1
-
24
-
-
0036284778
-
The anaphase-promoting complex. Proteolysis in mitosis and beyond
-
Peters J.M. The anaphase-promoting complex. Proteolysis in mitosis and beyond. Mol. Cell. 9:2002;931-943
-
(2002)
Mol. Cell
, vol.9
, pp. 931-943
-
-
Peters, J.M.1
-
25
-
-
0029160299
-
The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
-
Rieder C.L., Cole R.W., Khodjakov A., Sluder G. The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J. Cell Biol. 130:1995;941-948
-
(1995)
J. Cell Biol.
, vol.130
, pp. 941-948
-
-
Rieder, C.L.1
Cole, R.W.2
Khodjakov, A.3
Sluder, G.4
-
26
-
-
0028089758
-
The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase
-
Roberts B.T., Farr K.A., Hoyt M.A. The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase. Mol. Cell. Biol. 14:1994;8282-8291
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8282-8291
-
-
Roberts, B.T.1
Farr, K.A.2
Hoyt, M.A.3
-
28
-
-
0034704182
-
Waiting for anaphase: Mad2 and the spindle assembly checkpoint
-
Shah J.V., Cleveland D.W. Waiting for anaphase. Mad2 and the spindle assembly checkpoint Cell. 103:2000;997-1000
-
(2000)
Cell
, vol.103
, pp. 997-1000
-
-
Shah, J.V.1
Cleveland, D.W.2
-
29
-
-
0035844878
-
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity
-
Sharp-Baker H., Chen R.H. Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity. J. Cell Biol. 153:2001;1239-1250
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1239-1250
-
-
Sharp-Baker, H.1
Chen, R.H.2
-
30
-
-
0037093326
-
Crystal structure of the tetrameric Mad1-Mad2 core complex: Implications of a "safety belt" binding mechanism for the spindle checkpoint
-
Sironi L., Mapelli M., Knapp S., Antoni A.D., Jeang K.T., Musacchio A. Crystal structure of the tetrameric Mad1-Mad2 core complex. implications of a "safety belt" binding mechanism for the spindle checkpoint EMBO J. 21:2002;2496-2506
-
(2002)
EMBO J.
, vol.21
, pp. 2496-2506
-
-
Sironi, L.1
Mapelli, M.2
Knapp, S.3
Antoni, A.D.4
Jeang, K.T.5
Musacchio, A.6
-
31
-
-
0035802122
-
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
-
Sudakin V., Chan G.K., Yen T.J. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J. Cell Biol. 154:2001;925-936
-
(2001)
J. Cell Biol.
, vol.154
, pp. 925-936
-
-
Sudakin, V.1
Chan, G.K.2
Yen, T.J.3
-
32
-
-
4444336508
-
Functional analysis of the spindle-checkpoint proteins using an in vitro ubiquitination assay
-
Tang Z., Yu H. Functional analysis of the spindle-checkpoint proteins using an in vitro ubiquitination assay. Methods Mol. Biol. 281:2004;227-242
-
(2004)
Methods Mol. Biol.
, vol.281
, pp. 227-242
-
-
Tang, Z.1
Yu, H.2
-
34
-
-
0035694452
-
Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells
-
Taylor S.S., Hussein D., Wang Y., Elderkin S., Morrow C.J. Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells. J. Cell Sci. 114:2001;4385-4395
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4385-4395
-
-
Taylor, S.S.1
Hussein, D.2
Wang, Y.3
Elderkin, S.4
Morrow, C.J.5
-
35
-
-
0036732884
-
Distinct chromosome segregation roles for spindle checkpoint proteins
-
Warren C.D., Brady D.M., Johnston R.C., Hanna J.S., Hardwick K.G., Spencer F.A. Distinct chromosome segregation roles for spindle checkpoint proteins. Mol. Biol. Cell. 13:2002;3029-3041
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3029-3041
-
-
Warren, C.D.1
Brady, D.M.2
Johnston, R.C.3
Hanna, J.S.4
Hardwick, K.G.5
Spencer, F.A.6
-
36
-
-
0037416186
-
Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint
-
Yamaguchi S., Decottignies A., Nurse P. Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint. EMBO J. 22:2003;1075-1087
-
(2003)
EMBO J.
, vol.22
, pp. 1075-1087
-
-
Yamaguchi, S.1
Decottignies, A.2
Nurse, P.3
-
37
-
-
0036902234
-
Regulation of APC-Cdc20 by the spindle checkpoint
-
Yu H. Regulation of APC-Cdc20 by the spindle checkpoint. Curr. Opin. Cell Biol. 14:2002;706-714
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 706-714
-
-
Yu, H.1
-
38
-
-
0034630750
-
Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint
-
Yudkovsky Y., Shteinberg M., Listovsky T., Brandeis M., Hershko A. Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint. Biochem. Biophys. Res. Commun. 271:2000;299-304
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.271
, pp. 299-304
-
-
Yudkovsky, Y.1
Shteinberg, M.2
Listovsky, T.3
Brandeis, M.4
Hershko, A.5
|