Enzyme catalysis by hydrogen bonds: The balance between transition State binding and substrate binding in oxyanion holes

Journal of Organic Chemistry

Volumn 75, Issue 6, 2010, Pages 1831-1840

  Simón, Luis ^a,b   Goodman, Jonathan M ^a,b  

^a UNILEVER RESEARCH   (United Kingdom)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CAMBRIDGE; CHEMICAL EQUATIONS; CRYSTALLOGRAPHIC DATABASE; DATA SETS; DFT CALCULATION; ENZYME ACTIVE SITES; ENZYME CATALYSIS; ENZYME STRUCTURES; HYDROGEN BONDINGS; OXYANION HOLE; OXYANIONS; OXYGEN ANION; REACTION PATHWAYS; SMALL MOLECULES; STARTING MATERIALS; SUBSTRATE BINDING; TRANSITION STATE; TRANSITION STATE STRUCTURE; TRANSITION-STATE BINDING;

CATALYSTS; CHEMICAL REACTIONS; ENZYMES; HYDROGEN; OXYGEN; POSITIVE IONS; SULFUR COMPOUNDS;

HYDROGEN BONDS;

ANION; OXYGEN;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DATA BASE; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; HYDROGEN BOND; MOLECULAR INTERACTION;

ACYL COENZYME A; ANIONS; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; OXYGEN; PROTEIN STRUCTURE, TERTIARY; QUANTUM THEORY;

EID: 77949820602     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo901503d     Document Type: Article

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