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Volumn 24, Issue 4, 2010, Pages 285-301

Childhood medulloblastoma: Current status of biology and treatment

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; BETA CATENIN; CARBOPLATIN; CISPLATIN; CYCLOPAMINE; CYCLOPHOSPHAMIDE; ETOPOSIDE; FOLINIC ACID; LOMUSTINE; METHOTREXATE; NOTCH RECEPTOR; OXALIPLATIN; PREDNISONE; PROTEIN PATCHED 1; PROTEIN TYROSINE KINASE; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TEMOZOLOMIDE; TOPOTECAN; TRASTUZUMAB; VINCRISTINE; WNT1 PROTEIN;

EID: 77949599402     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/11530140-000000000-00000     Document Type: Review
Times cited : (25)

References (135)
  • 1
    • 77949580858 scopus 로고    scopus 로고
    • CBTRUS [online]. Hinsdale (IL): Central Brain Tumor Registry of United States [Accessed 2010 Jan 26]
    • CBTRUS. Statistical report: primary brain tumors in the United States 2005-2006 [online]. Hinsdale (IL): Central Brain Tumor Registry of United States 2009. Available from URL: http://www.cbtrus.org [Accessed 2010 Jan 26]
    • (2009) Statistical Report: Primary Brain Tumors in the United States 2005-2006
  • 2
    • 0034518223 scopus 로고    scopus 로고
    • Adult medullo-blastoma: Prognostic factors and patterns of relapse
    • Sep discussion 31-32
    • Chan AW, Tarbell NJ, Black PM, et al. Adult medullo-blastoma: prognostic factors and patterns of relapse. Neurosurgery 2000 Sep; 47 (3): 623-31; discussion 31-32
    • (2000) Neurosurgery , vol.47 , Issue.3 , pp. 623-31
    • Chan, A.W.1    Tarbell, N.J.2    Black, P.M.3
  • 3
    • 0029757513 scopus 로고    scopus 로고
    • Is there a correlation between duration of presenting symptoms and stage of medullo-blastoma at the time of diagnosis?
    • Aug 15
    • Halperin EC, Friedman HS. Is there a correlation between duration of presenting symptoms and stage of medullo-blastoma at the time of diagnosis? Cancer 1996 Aug 15; 78 (4): 874-880
    • (1996) Cancer , vol.78 , Issue.4 , pp. 874-880
    • Halperin, E.C.1    Friedman, H.S.2
  • 4
    • 0025391815 scopus 로고
    • A clinicopathologic and immunohistochemical analysis of 53 cases of me-dulloblastoma with emphasis on synaptophysin expression
    • Mar
    • Coffin CM, Braun JT, Wick MR, et al. A clinicopathologic and immunohistochemical analysis of 53 cases of me-dulloblastoma with emphasis on synaptophysin expression. Mod Pathol 1990 Mar; 3 (2): 164-170
    • (1990) Mod Pathol , vol.3 , Issue.2 , pp. 164-170
    • Coffin, C.M.1    Braun, J.T.2    Wick, M.R.3
  • 5
    • 0023264106 scopus 로고
    • Differentiation in the medulloblastoma: A histological and immunohisto-chemical study
    • Burger PC, Grahmann FC, Bliestle A, et al. Differentiation in the medulloblastoma: a histological and immunohisto-chemical study. Acta Neuropathol 1987; 73 (2): 115-123
    • (1987) Acta Neuropathol , vol.73 , Issue.2 , pp. 115-123
    • Burger, P.C.1    Grahmann, F.C.2    Bliestle, A.3
  • 6
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007; 114 (2): 97-109
    • (2007) Acta Neuropathol , vol.114 , Issue.2 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 7
    • 0041625921 scopus 로고    scopus 로고
    • Anaplasia and grading in me-dulloblastomas
    • Jul
    • Eberhart CG, Burger PC. Anaplasia and grading in me-dulloblastomas. Brain Pathol 2003 Jul; 13 (3): 376-385
    • (2003) Brain Pathol , vol.13 , Issue.3 , pp. 376-385
    • Eberhart, C.G.1    Burger, P.C.2
  • 8
    • 0037080303 scopus 로고    scopus 로고
    • Histo-pathologic grading of medulloblastomas: A Pediatric Oncology Group study
    • Eberhart CG, Kepner JL, Goldthwaite PT, et al. Histo-pathologic grading of medulloblastomas: a Pediatric Oncology Group study. Cancer 2002 Jan 15; 94 (2): 552-560
    • (2002) Cancer , vol.94 , Issue.2 , pp. 552-560
    • Eberhart, C.G.1    Kepner, J.L.2    Goldthwaite, P.T.3
  • 9
    • 1842614251 scopus 로고    scopus 로고
    • Clinical, histo-pathologic, and molecular markers of prognosis: Toward a new disease risk stratification system for medullo-blastoma
    • Mar 15
    • Gajjar A, Hernan R, Kocak M, et al. Clinical, histo-pathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medullo-blastoma. J Clin Oncol 2004 Mar 15; 22 (6): 984-993
    • (2004) J Clin Oncol , vol.22 , Issue.6 , pp. 984-993
    • Gajjar, A.1    Hernan, R.2    Kocak, M.3
  • 10
    • 0038309244 scopus 로고    scopus 로고
    • Medulloblastoma: Present concepts of stratification into risk groups
    • Jul
    • Packer RJ, Rood BR, MacDonald TJ. Medulloblastoma: present concepts of stratification into risk groups. Pediatr Neurosurg 2003 Jul; 39 (2): 60-67
    • (2003) Pediatr Neurosurg , vol.39 , Issue.2 , pp. 60-67
    • Packer, R.J.1    Rood, B.R.2    MacDonald, T.J.3
  • 11
    • 0033050817 scopus 로고    scopus 로고
    • Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: Conclusions from the Children's Cancer Group 921 randomized phase III study
    • Zeltzer PM, Boyett JM, Finlay JL, et al. Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study. J Clin Oncol 1999; 17 (3): 832-845
    • (1999) J Clin Oncol , vol.17 , Issue.3 , pp. 832-845
    • Zeltzer, P.M.1    Boyett, J.M.2    Finlay, J.L.3
  • 12
    • 0025093160 scopus 로고
    • False-positive spinal MR findings for subarachnoid spread of primary CNS tumor in postoperative pediatric patients
    • Wiener MD, Boyko OB, Friedman HS, et al. False-positive spinal MR findings for subarachnoid spread of primary CNS tumor in postoperative pediatric patients. AJNR Am J Neuroradiol 1990; 11 (6): 1100-1103
    • (1990) AJNR Am J Neuroradiol , vol.11 , Issue.6 , pp. 1100-1103
    • Wiener, M.D.1    Boyko, O.B.2    Friedman, H.S.3
  • 13
    • 20044371594 scopus 로고    scopus 로고
    • Treatment of early childhood medulloblastoma by postoperative chemotherapy alone
    • Mar 10
    • Rutkowski S, Bode U, Deinlein F, et al. Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med 2005 Mar 10; 352 (10): 978-986
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 978-986
    • Rutkowski, S.1    Bode, U.2    Deinlein, F.3
  • 14
    • 42349104993 scopus 로고    scopus 로고
    • Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "head Start" i and II protocols
    • Jun
    • Dhall G, Grodman H, Ji L, et al. Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocols. Pediatr Blood Cancer 2008 Jun; 50 (6): 1169-1175
    • (2008) Pediatr Blood Cancer , vol.50 , Issue.6 , pp. 1169-1175
    • Dhall, G.1    Grodman, H.2    Ji, L.3
  • 15
    • 33748660920 scopus 로고    scopus 로고
    • Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medullo-blastoma
    • Sep 1
    • Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medullo-blastoma. J Clin Oncol 2006 Sep 1; 24 (25): 4202-4208
    • (2006) J Clin Oncol , vol.24 , Issue.25 , pp. 4202-4208
    • Packer, R.J.1    Gajjar, A.2    Vezina, G.3
  • 16
  • 17
    • 33749044182 scopus 로고    scopus 로고
    • Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective multicentre trial
    • Oct
    • Gajjar A, Chintagumpala M, Ashley D, et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol 2006 Oct; 7 (10): 813-820
    • (2006) Lancet Oncol , vol.7 , Issue.10 , pp. 813-820
    • Gajjar, A.1    Chintagumpala, M.2    Ashley, D.3
  • 18
    • 27244443906 scopus 로고    scopus 로고
    • Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies
    • Oct 1
    • Fouladi M, Gilger E, Kocak M, et al. Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies. J Clin Oncol 2005 Oct 1; 23 (28): 7152-7160
    • (2005) J Clin Oncol , vol.23 , Issue.28 , pp. 7152-7160
    • Fouladi, M.1    Gilger, E.2    Kocak, M.3
  • 19
    • 32944482676 scopus 로고    scopus 로고
    • Multiagent chemo-therapy and deferred radiotherapy in infants with malignant brain tumors: A report from the Children's Cancer Group
    • Oct 20
    • Geyer JR, Sposto R, Jennings M, et al. Multiagent chemo-therapy and deferred radiotherapy in infants with malignant brain tumors: a report from the Children's Cancer Group. J Clin Oncol 2005 Oct 20; 23 (30): 7621-7631
    • (2005) J Clin Oncol , vol.23 , Issue.30 , pp. 7621-7631
    • Geyer, J.R.1    Sposto, R.2    Jennings, M.3
  • 20
    • 0028145103 scopus 로고
    • Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: A report from the Childrens Cancer Group
    • Aug
    • Geyer JR, Zeltzer PM, Boyett JM, et al. Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: a report from the Childrens Cancer Group. J Clin Oncol 1994 Aug; 12 (8): 1607-1615
    • (1994) J Clin Oncol , vol.12 , Issue.8 , pp. 1607-1615
    • Geyer, J.R.1    Zeltzer, P.M.2    Boyett, J.M.3
  • 21
    • 0033108117 scopus 로고    scopus 로고
    • The treat-ment of malignant brain tumors in infants and very young children: An update of the Pediatric Oncology Group experience
    • Apr
    • Duffner PK, Horowitz ME, Krischer JP, et al. The treat-ment of malignant brain tumors in infants and very young children: an update of the Pediatric Oncology Group experience. Neuro Oncol 1999 Apr; 1 (2): 152-161
    • (1999) Neuro Oncol , vol.1 , Issue.2 , pp. 152-161
    • Duffner, P.K.1    Horowitz, M.E.2    Krischer, J.P.3
  • 22
    • 0027314975 scopus 로고
    • Post-operative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors
    • Jun 17
    • Duffner PK, Horowitz ME, Krischer JP, et al. Post-operative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med 1993 Jun 17; 328 (24): 1725-1731
    • (1993) N Engl J Med , vol.328 , Issue.24 , pp. 1725-1731
    • Duffner, P.K.1    Horowitz, M.E.2    Krischer, J.P.3
  • 23
    • 22944436550 scopus 로고    scopus 로고
    • Treatment of me-dulloblastoma with postoperative chemotherapy alone: An SFOP prospective trial in young children
    • Grill J, Sainte-Rose C, Jouvet A, et al. Treatment of me-dulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children. Lancet Oncol 2005; 6: 573-580
    • (2005) Lancet Oncol , vol.6 , pp. 573-580
    • Grill, J.1    Sainte-Rose, C.2    Jouvet, A.3
  • 24
    • 37049037998 scopus 로고    scopus 로고
    • Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91: Implications for investigating childhood medulloblastoma
    • Nov-Dec
    • Grotzer MA, von Hoff K, von Bueren AO, et al. Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91: implications for investigating childhood medulloblastoma. Klin Padiatr 2007 Nov-Dec; 219 (6): 312-317
    • (2007) Klin Padiatr , vol.219 , Issue.6 , pp. 312-317
    • Grotzer, M.A.1    Von Hoff, K.2    Von Bueren, A.O.3
  • 25
    • 32944461274 scopus 로고    scopus 로고
    • Beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: The United Kingdom Children's Cancer Study Group Brain Tumour Committee
    • Nov 1
    • Ellison DW, Onilude OE, Lindsey JC, et al. beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee. J Clin Oncol 2005 Nov 1; 23 (31): 7951-7957
    • (2005) J Clin Oncol , vol.23 , Issue.31 , pp. 7951-7957
    • Ellison, D.W.1    Onilude, O.E.2    Lindsey, J.C.3
  • 26
    • 2442681686 scopus 로고    scopus 로고
    • Histopathological and molecular prognostic markers in medulloblastoma: C-myc, N-myc, TrkC, and anaplasia
    • May
    • Eberhart CG, Kratz J, Wang Y, et al. Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia. J Neuropathol Exp Neurol 2004 May; 63 (5): 441-449
    • (2004) J Neuropathol Exp Neurol , vol.63 , Issue.5 , pp. 441-449
    • Eberhart, C.G.1    Kratz, J.2    Wang, Y.3
  • 27
    • 0028568009 scopus 로고
    • Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
    • Segal RA, Goumnerova LC, Kwon YK, et al. Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci USA 1994; 91 (26): 12867-12871
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.26 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3
  • 28
    • 0036020503 scopus 로고    scopus 로고
    • Immunohisto-chemical markers for prognosis of average-risk pediatric medulloblastomas: The effect of apoptotic index, TrkC, and C-myc expression
    • Korshunov A, Savostikova M, Ozerov S. Immunohisto-chemical markers for prognosis of average-risk pediatric medulloblastomas: the effect of apoptotic index, TrkC, and C-myc expression. J Neurooncol 2002; 58 (3): 271-279
    • (2002) J Neurooncol , vol.58 , Issue.3 , pp. 271-279
    • Korshunov, A.1    Savostikova, M.2    Ozerov, S.3
  • 29
    • 0036245047 scopus 로고    scopus 로고
    • MYCC and MYCN oncogene amplification in medulloblastoma: A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group
    • May
    • Aldosari N, Bigner SH, Burger PC, et al. MYCC and MYCN oncogene amplification in medulloblastoma: a fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group. Arch Pathol Lab Med 2002 May; 126 (5): 540-544
    • (2002) Arch Pathol Lab Med , vol.126 , Issue.5 , pp. 540-544
    • Aldosari, N.1    Bigner, S.H.2    Burger, P.C.3
  • 30
    • 0034890563 scopus 로고    scopus 로고
    • MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma
    • Aug
    • Grotzer MA, Hogarty MD, Janss AJ, et al. MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma. Clin Cancer Res 2001 Aug; 7 (8): 2425-2433
    • (2001) Clin Cancer Res , vol.7 , Issue.8 , pp. 2425-2433
    • Grotzer, M.A.1    Hogarty, M.D.2    Janss, A.J.3
  • 31
    • 0037224320 scopus 로고    scopus 로고
    • ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma
    • Jan 1
    • Hernan R, Fasheh R, Calabrese C, et al. ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res 2003 Jan 1; 63 (1): 140-148
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 140-148
    • Hernan, R.1    Fasheh, R.2    Calabrese, C.3
  • 32
    • 0031803734 scopus 로고    scopus 로고
    • Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome
    • Jul
    • Scheurlen WG, Schwabe GC, Joos S, et al. Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J Clin Oncol 1998 Jul; 16 (7): 2478-2485
    • (1998) J Clin Oncol , vol.16 , Issue.7 , pp. 2478-2485
    • Scheurlen, W.G.1    Schwabe, G.C.2    Joos, S.3
  • 33
    • 33751042197 scopus 로고    scopus 로고
    • Histopathological prognostic factors in medulloblastoma: High expression of survivin is related to unfavourable outcome
    • Haberler C, Slavc I, Czech T, et al. Histopathological prognostic factors in medulloblastoma: high expression of survivin is related to unfavourable outcome. Eur J Cancer 2006; 42 (17): 2996-3003
    • (2006) Eur J Cancer , vol.42 , Issue.17 , pp. 2996-3003
    • Haberler, C.1    Slavc, I.2    Czech, T.3
  • 34
    • 0037273964 scopus 로고    scopus 로고
    • What's new in neuro-oncology? Recent advances in medulloblastoma
    • Ellison DW, Clifford SC, Gajjar A, et al. What's new in neuro-oncology? Recent advances in medulloblastoma. Eur J Paediatr Neurol 2003; 7 (2): 53-66
    • (2003) Eur J Paediatr Neurol , vol.7 , Issue.2 , pp. 53-66
    • Ellison, D.W.1    Clifford, S.C.2    Gajjar, A.3
  • 35
    • 45549091581 scopus 로고    scopus 로고
    • Medulloblastoma stem cells
    • Jun 10
    • Fan X, Eberhart CG. Medulloblastoma stem cells. J Clin Oncol 2008 Jun 10; 26 (17): 2821-2827
    • (2008) J Clin Oncol , vol.26 , Issue.17 , pp. 2821-2827
    • Fan, X.1    Eberhart, C.G.2
  • 36
    • 34250892622 scopus 로고    scopus 로고
    • Tumorigenesis in the brain: Location, location, location
    • Jun 15
    • Gilbertson RJ, Gutmann DH. Tumorigenesis in the brain: location, location, location. Cancer Res 2007 Jun 15; 67 (12): 5579-5582
    • (2007) Cancer Res , vol.67 , Issue.12 , pp. 5579-5582
    • Gilbertson, R.J.1    Gutmann, D.H.2
  • 37
    • 1642307767 scopus 로고    scopus 로고
    • Medulloblastoma: Signalling a change in treatment
    • Apr
    • Gilbertson RJ. Medulloblastoma: signalling a change in treatment. Lancet Oncol 2004 Apr; 5 (4): 209-218
    • (2004) Lancet Oncol , vol.5 , Issue.4 , pp. 209-218
    • Gilbertson, R.J.1
  • 38
    • 29644434598 scopus 로고    scopus 로고
    • Molecular biology of medullo-blastoma: Will it ever make a difference to clinical management?
    • Dec
    • Gilbertson RJ, Gajjar A. Molecular biology of medullo-blastoma: will it ever make a difference to clinical management? J Neurooncol 2005 Dec; 75 (3): 273-278
    • (2005) J Neurooncol , vol.75 , Issue.3 , pp. 273-278
    • Gilbertson, R.J.1    Gajjar, A.2
  • 39
    • 58149151088 scopus 로고    scopus 로고
    • Nevoid basal cell carcinoma syndrome (Gorlin syndrome)
    • Lo Muzio L. Nevoid basal cell carcinoma syndrome (Gorlin syndrome). Orphanet J Rare Dis 2008; 3 (32): 1-16
    • (2008) Orphanet J Rare Dis , vol.3 , Issue.32 , pp. 1-16
    • Lo Muzio, L.1
  • 40
    • 15844386165 scopus 로고    scopus 로고
    • Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
    • Jun 14
    • Hahn H, Wicking C, Zaphiropoulous PG, et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996 Jun 14; 85 (6): 841-851
    • (1996) Cell , vol.85 , Issue.6 , pp. 841-851
    • Hahn, H.1    Wicking, C.2    Zaphiropoulous, P.G.3
  • 41
    • 15844381336 scopus 로고    scopus 로고
    • Human homolog of patched, a candidate gene for the basal cell nevus syndrome
    • Jun 14
    • Johnson RL, Rothman AL, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996 Jun 14; 272 (5268): 1668-1671
    • (1996) Science , vol.272 , Issue.5268 , pp. 1668-1671
    • Johnson, R.L.1    Rothman, A.L.2    Xie, J.3
  • 42
    • 0032959871 scopus 로고    scopus 로고
    • Control of neuronal pre-cursor proliferation in the cerebellum by Sonic hedgehog
    • Jan
    • Wechsler-Reya RJ, Scott MP. Control of neuronal pre-cursor proliferation in the cerebellum by Sonic hedgehog. Neuron 1999 Jan; 22 (1): 103-114
    • (1999) Neuron , vol.22 , Issue.1 , pp. 103-114
    • Wechsler-Reya, R.J.1    Scott, M.P.2
  • 43
    • 0034927062 scopus 로고    scopus 로고
    • The developmental biology of brain tumors
    • Wechsler-Reya R, Scott MP. The developmental biology of brain tumors. Annu Rev Neurosci 2001; 24: 385-428
    • (2001) Annu Rev Neurosci , vol.24 , pp. 385-428
    • Wechsler-Reya, R.1    Scott, M.P.2
  • 44
    • 0141816821 scopus 로고    scopus 로고
    • A molecular fingerprint for medulloblastoma
    • Sep 1
    • Lee Y, Miller HL, Jensen P, et al. A molecular fingerprint for medulloblastoma. Cancer Res 2003 Sep 1; 63 (17): 5428-5437
    • (2003) Cancer Res , vol.63 , Issue.17 , pp. 5428-5437
    • Lee, Y.1    Miller, H.L.2    Jensen, P.3
  • 45
    • 0030913169 scopus 로고    scopus 로고
    • Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched
    • Jun 1
    • Pietsch T, Waha A, Koch A, et al. Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 1997 Jun 1; 57 (11): 2085-2088
    • (1997) Cancer Res , vol.57 , Issue.11 , pp. 2085-2088
    • Pietsch, T.1    Waha, A.2    Koch, A.3
  • 46
    • 0033990220 scopus 로고    scopus 로고
    • Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma
    • Jan
    • Zurawel RH, Allen C, Chiappa S, et al. Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma. Genes Chromosomes Cancer 2000 Jan; 27 (1): 44-51
    • (2000) Genes Chromosomes Cancer , vol.27 , Issue.1 , pp. 44-51
    • Zurawel, R.H.1    Allen, C.2    Chiappa, S.3
  • 47
    • 0034123010 scopus 로고    scopus 로고
    • Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice
    • May
    • Zurawel RH, Allen C, Wechsler-Reya R, et al. Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice. Genes Chromosomes Cancer 2000 May; 28 (1): 77-81
    • (2000) Genes Chromosomes Cancer , vol.28 , Issue.1 , pp. 77-81
    • Zurawel, R.H.1    Allen, C.2    Wechsler-Reya, R.3
  • 48
    • 27644512310 scopus 로고    scopus 로고
    • Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients
    • Jul 1
    • Pan E, Pellarin M, Holmes E, et al. Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients. Clin Cancer Res 2005 Jul 1; 11 (13): 4733-4740
    • (2005) Clin Cancer Res , vol.11 , Issue.13 , pp. 4733-4740
    • Pan, E.1    Pellarin, M.2    Holmes, E.3
  • 49
    • 3242722919 scopus 로고    scopus 로고
    • REN(KCTD11) is a suppressor of hedgehog signalling and is deleted in human medulloblastoma
    • Jul 20
    • Di Marcotullio L, Ferretti E, De Smaele E, et al. REN(KCTD11) is a suppressor of hedgehog signalling and is deleted in human medulloblastoma. Proc Natl Acad Sci USA 2004 Jul 20; 101 (29): 10833-10838
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.29 , pp. 10833-10838
    • Di Marcotullio, L.1    Ferretti, E.2    De Smaele, E.3
  • 50
    • 13944275921 scopus 로고    scopus 로고
    • Chromo-some 17p deletion in human medulloblastoma: A missing checkpoint in the Hedgehog pathway
    • Oct
    • De Smaele E, Di Marcotullio L, Ferretti E, et al. Chromo-some 17p deletion in human medulloblastoma: a missing checkpoint in the Hedgehog pathway. Cell Cycle 2004 Oct; 3 (10): 1263-1266
    • (2004) Cell Cycle , vol.3 , Issue.10 , pp. 1263-1266
    • De Smaele, E.1    Di Marcotullio, L.2    Ferretti, E.3
  • 51
    • 34748851341 scopus 로고    scopus 로고
    • Cell and molecular biology of Notch
    • Sep
    • Fiuza UM, Arias AM. Cell and molecular biology of Notch. J Endocrinol 2007 Sep; 194 (3): 459-474
    • (2007) J Endocrinol , vol.194 , Issue.3 , pp. 459-474
    • Fiuza, U.M.1    Arias, A.M.2
  • 52
    • 33947214529 scopus 로고    scopus 로고
    • Notch signalling, gamma-secretase inhibitors, and cancer therapy
    • Mar 1
    • Shih Ie M, Wang TL. Notch signalling, gamma-secretase inhibitors, and cancer therapy. Cancer Res 2007 Mar 1; 67 (5): 1879-1882
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 1879-1882
    • Shih Ie, M.1    Wang, T.L.2
  • 53
    • 0033090560 scopus 로고    scopus 로고
    • Phylogenetic analysis of ver-tebrate and invertebrate Delta/Serrate/LAG-2 (DSL) proteins
    • Mar
    • Lissemore JL, Starmer WT. Phylogenetic analysis of ver-tebrate and invertebrate Delta/Serrate/LAG-2 (DSL) proteins. Mol Phylogenet Evol 1999 Mar; 11 (2): 308-319
    • (1999) Mol Phylogenet Evol , vol.11 , Issue.2 , pp. 308-319
    • Lissemore, J.L.1    Starmer, W.T.2
  • 54
    • 6044221204 scopus 로고    scopus 로고
    • Cancer stem cells in nervous system tumors
    • Sep 20
    • Singh SK, Clarke ID, Hide T, et al. Cancer stem cells in nervous system tumors. Oncogene 2004 Sep 20; 23 (43): 7267-7273
    • (2004) Oncogene , vol.23 , Issue.43 , pp. 7267-7273
    • Singh, S.K.1    Clarke, I.D.2    Hide, T.3
  • 55
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Sep 15
    • Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003 Sep 15; 63 (18): 5821-5828
    • (2003) Cancer Res , vol.63 , Issue.18 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 56
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Nov 18
    • Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004 Nov 18; 432 (7015): 396-401
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 57
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • Aug 1
    • Fan X, Matsui W, Khaki L, et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 2006 Aug 1;66 (15): 7445-7452
    • (2006) Cancer Res , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3
  • 58
    • 0034033921 scopus 로고    scopus 로고
    • Nuclear localization and mutation of beta-catenin in medulloblastomas
    • Apr
    • Eberhart CG, Tihan T, Burger PC. Nuclear localization and mutation of beta-catenin in medulloblastomas. J Neuropathol Exp Neurol 2000 Apr; 59 (4): 333-337
    • (2000) J Neuropathol Exp Neurol , vol.59 , Issue.4 , pp. 333-337
    • Eberhart, C.G.1    Tihan, T.2    Burger, P.C.3
  • 59
    • 33751234205 scopus 로고    scopus 로고
    • Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
    • Nov
    • Clifford SC, Lusher ME, Lindsey JC, et al. Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle 2006 Nov; 5 (22): 2666-2670
    • (2006) Cell Cycle , vol.5 , Issue.22 , pp. 2666-2670
    • Clifford, S.C.1    Lusher, M.E.2    Lindsey, J.C.3
  • 60
    • 56249131423 scopus 로고    scopus 로고
    • Radiobiologic response of medulloblastoma cell lines: Involvement of beta-catenin?
    • Salaroli R, Di Tomaso T, Ronchi A, et al. Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin? J Neurooncol 2008; 90 (3): 243-251
    • (2008) J Neurooncol , vol.90 , Issue.3 , pp. 243-251
    • Salaroli, R.1    Di Tomaso, T.2    Ronchi, A.3
  • 61
    • 0037011776 scopus 로고    scopus 로고
    • Expression of stabi-lized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation
    • Dec 2
    • Kratz JE, Stearns D, Huso DL, et al. Expression of stabi-lized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation. BMC Cancer 2002 Dec 2; 233: 1-9
    • (2002) BMC Cancer , vol.233 , pp. 1-9
    • Kratz, J.E.1    Stearns, D.2    Huso, D.L.3
  • 62
    • 0030741967 scopus 로고    scopus 로고
    • Prognostic significance of HER2 and HER4 coexpressionin childhood medulloblastoma
    • Aug 1
    • Gilbertson RJ, Perry RH, Kelly PJ, et al. Prognostic significance of HER2 and HER4 coexpressionin childhood medulloblastoma. Cancer Res 1997 Aug 1; 57 (15): 3272-3280
    • (1997) Cancer Res , vol.57 , Issue.15 , pp. 3272-3280
    • Gilbertson, R.J.1    Perry, R.H.2    Kelly, P.J.3
  • 63
    • 0035445646 scopus 로고    scopus 로고
    • Clinical and molecular stratification of disease risk in medullo-blastoma
    • Sep 1
    • Gilbertson R, Wickramasinghe C, Hernan R, et al. Clinical and molecular stratification of disease risk in medullo-blastoma. Br J Cancer 2001 Sep 1; 85 (5): 705-712
    • (2001) Br J Cancer , vol.85 , Issue.5 , pp. 705-712
    • Gilbertson, R.1    Wickramasinghe, C.2    Hernan, R.3
  • 64
    • 35648956157 scopus 로고    scopus 로고
    • Functional VEGF and VEGF receptors are expressed in human me-dulloblastomas
    • Oct
    • Slongo ML, Molena B, Brunati AM, et al. Functional VEGF and VEGF receptors are expressed in human me-dulloblastomas. Neuro Oncol 2007 Oct; 9 (4): 384-392
    • (2007) Neuro Oncol , vol.9 , Issue.4 , pp. 384-392
    • Slongo, M.L.1    Molena, B.2    Brunati, A.M.3
  • 65
    • 0034145706 scopus 로고    scopus 로고
    • Autocrine secreted insulin-like growth factor-I stimulates MAP kinase-dependent mitogenic effects in human primitive neuro-ectodermal tumor/medulloblastoma
    • Mar
    • Patti R, Reddy CD, Geoerger B, et al. Autocrine secreted insulin-like growth factor-I stimulates MAP kinase-dependent mitogenic effects in human primitive neuro-ectodermal tumor/medulloblastoma. Int J Oncol 2000 Mar; 16 (3): 577-584
    • (2000) Int J Oncol , vol.16 , Issue.3 , pp. 577-584
    • Patti, R.1    Reddy, C.D.2    Geoerger, B.3
  • 66
    • 0034665975 scopus 로고    scopus 로고
    • Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma
    • Sep 15
    • Hahn H, Wojnowski L, Specht K, et al. Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J Biol Chem 2000 Sep 15; 275 (37): 28341-28344
    • (2000) J Biol Chem , vol.275 , Issue.37 , pp. 28341-28344
    • Hahn, H.1    Wojnowski, L.2    Specht, K.3
  • 67
    • 38549146069 scopus 로고    scopus 로고
    • Functional and mol-ecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma
    • Feb
    • Li Y, Guessous F, Johnson EB, et al. Functional and mol-ecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma. Lab Invest 2008 Feb; 88 (2): 98-111
    • (2008) Lab Invest , vol.88 , Issue.2 , pp. 98-111
    • Li, Y.1    Guessous, F.2    Johnson, E.B.3
  • 68
    • 27144524893 scopus 로고    scopus 로고
    • The scatter factor/hepatocyte growth factor: C-met pathway in human embryonal central nervous system tumor malignancy
    • Oct 15
    • Li Y, Lal B, Kwon S, et al. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy. Cancer Res 2005 Oct 15; 65 (20): 9355-9362
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9355-9362
    • Li, Y.1    Lal, B.2    Kwon, S.3
  • 69
    • 0035863498 scopus 로고    scopus 로고
    • Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched
    • Jan 15
    • Wetmore C, Eberhart DE, Curran T. Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched. Cancer Res 2001 Jan 15; 61 (2): 513-516
    • (2001) Cancer Res , vol.61 , Issue.2 , pp. 513-516
    • Wetmore, C.1    Eberhart, D.E.2    Curran, T.3
  • 70
    • 7444228699 scopus 로고    scopus 로고
    • The SmoA1 mouse model reveals that notch signalling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
    • Nov 1
    • Hallahan AR, Pritchard JI, Hansen S, et al. The SmoA1 mouse model reveals that notch signalling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas. Cancer Res 2004 Nov 1; 64 (21): 7794-7800
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7794-7800
    • Hallahan, A.R.1    Pritchard, J.I.2    Hansen, S.3
  • 71
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • Aug 22
    • Goodrich LV, Milenkovic L, Higgins KM, et al. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 1997 Aug 22; 277 (5329): 1109-1113
    • (1997) Science , vol.277 , Issue.5329 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3
  • 72
    • 40949158954 scopus 로고    scopus 로고
    • The Smo/Smo model: Hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread
    • Mar 15
    • Hatton BA, Villavicencio EH, Tsuchiya KD, et al. The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread. Cancer Res 2008 Mar 15; 68 (6): 1768-1776
    • (2008) Cancer Res , vol.68 , Issue.6 , pp. 1768-1776
    • Hatton, B.A.1    Villavicencio, E.H.2    Tsuchiya, K.D.3
  • 73
    • 20444468917 scopus 로고    scopus 로고
    • Targeting medulloblastoma: Small-molecule inhibitors of the Sonic hedgehog pathway as potential cancer therapeutics
    • Jun 15
    • Romer J, Curran T. Targeting medulloblastoma: small-molecule inhibitors of the Sonic hedgehog pathway as potential cancer therapeutics. Cancer Res 2005 Jun 15; 65 (12): 4975-4978
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 4975-4978
    • Romer, J.1    Curran, T.2
  • 74
    • 4544285754 scopus 로고    scopus 로고
    • Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-) p53(-/-) mice
    • Sep
    • Romer JT, Kimura H, Magdaleno S, et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 2004 Sep; 6 (3): 229-240
    • (2004) Cancer Cell , vol.6 , Issue.3 , pp. 229-240
    • Romer, J.T.1    Kimura, H.2    Magdaleno, S.3
  • 75
    • 0033554684 scopus 로고    scopus 로고
    • On behalf of the Children's Cancer Group. Treatment of high-risk neuro-blastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid
    • Oct 14
    • Matthay KK, Villablanca JG, Seeger RC, et al., on behalf of the Children's Cancer Group. Treatment of high-risk neuro-blastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. N Engl J Med 1999 Oct 14; 341 (16): 1165-1173
    • (1999) N Engl J Med , vol.341 , Issue.16 , pp. 1165-1173
    • Matthay, K.K.1    Villablanca, J.G.2    Seeger, R.C.3
  • 76
    • 41949111045 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: From highly fatal to highly curable
    • Mar 1
    • Wang ZY, Chen Z. Acute promyelocytic leukemia: from highly fatal to highly curable. Blood 2008 Mar 1; 111 (5): 2505-2515
    • (2008) Blood , vol.111 , Issue.5 , pp. 2505-2515
    • Wang, Z.Y.1    Chen, Z.2
  • 77
    • 35448998549 scopus 로고    scopus 로고
    • All-trans-retinoic acid in-duces cell growth arrest in a human medulloblastoma cell line
    • Sep
    • Chang Q, Chen Z, You J, et al. All-trans-retinoic acid in-duces cell growth arrest in a human medulloblastoma cell line. J Neurooncol 2007 Sep; 84 (3): 263-267
    • (2007) J Neurooncol , vol.84 , Issue.3 , pp. 263-267
    • Chang, Q.1    Chen, Z.2    You, J.3
  • 78
    • 0042967678 scopus 로고    scopus 로고
    • BMP-2 mediates retinoid-induced apoptosis in medullo-blastoma cells through a paracrine effect
    • Aug
    • Hallahan AR, Pritchard JI, Chandraratna RA, et al. BMP-2 mediates retinoid-induced apoptosis in medullo-blastoma cells through a paracrine effect. Nat Med 2003 Aug; 9 (8): 1033-1038
    • (2003) Nat Med , vol.9 , Issue.8 , pp. 1033-1038
    • Hallahan, A.R.1    Pritchard, J.I.2    Chandraratna, R.A.3
  • 79
    • 29844431881 scopus 로고    scopus 로고
    • Anticancer effects of fenretinide in human medullo-blastoma
    • Damodar Reddy C, Guttapalli A, Adamson PC, et al. Anticancer effects of fenretinide in human medullo-blastoma. Cancer Lett 2006 Jan 18; 231 (2): 262-269
    • (2006) Cancer Lett , vol.231 , Issue.2 , pp. 262-269
    • Damodar Reddy, C.1    Guttapalli, A.2    Adamson, P.C.3
  • 80
    • 41549151359 scopus 로고    scopus 로고
    • Response of pre-clinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA)
    • Apr
    • Spiller SE, Ditzler SH, Pullar BJ, et al. Response of pre-clinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA). J Neurooncol 2008 Apr; 87 (2): 133-141
    • (2008) J Neurooncol , vol.87 , Issue.2 , pp. 133-141
    • Spiller, S.E.1    Ditzler, S.H.2    Pullar, B.J.3
  • 81
    • 40349106236 scopus 로고    scopus 로고
    • Gamma-secretase modulation and its promise for Alzheimer's disease: A medicinal chemistry perspective
    • Peretto I, La Porta E. Gamma-secretase modulation and its promise for Alzheimer's disease: a medicinal chemistry perspective. Curr Top Med Chem 2008; 8 (1): 38-46
    • (2008) Curr Top Med Chem , vol.8 , Issue.1 , pp. 38-46
    • Peretto, I.1    La Porta, E.2
  • 82
    • 55849121517 scopus 로고    scopus 로고
    • Gamma-secretase modulators: Hopes and setbacks for the future of Alzheimer's treatment
    • Nov
    • Evin G. Gamma-secretase modulators: hopes and setbacks for the future of Alzheimer's treatment. Expert Rev Neurother 2008 Nov; 8 (11): 1611-1613
    • (2008) Expert Rev Neurother , vol.8 , Issue.11 , pp. 1611-1613
    • Evin, G.1
  • 83
    • 0037200078 scopus 로고    scopus 로고
    • Medulloblastoma growth inhibition by hedgehog pathway blockade
    • Aug 30
    • Berman DM, Karhadkar SS, Hallahan AR, et al. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 2002 Aug 30; 297 (5586): 1559-1561
    • (2002) Science , vol.297 , Issue.5586 , pp. 1559-1561
    • Berman, D.M.1    Karhadkar, S.S.2    Hallahan, A.R.3
  • 84
    • 70349244812 scopus 로고    scopus 로고
    • Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
    • Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med 2009; 361 (12): 1173-1178
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1173-1178
    • Rudin, C.M.1    Hann, C.L.2    Laterra, J.3
  • 85
    • 38549160823 scopus 로고    scopus 로고
    • Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors
    • Feb
    • Emanuel SL, Hughes TV, Adams M, et al. Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors. Mol Pharmacol 2008 Feb; 73 (2): 338-348
    • (2008) Mol Pharmacol , vol.73 , Issue.2 , pp. 338-348
    • Emanuel, S.L.1    Hughes, T.V.2    Adams, M.3
  • 86
    • 0033518310 scopus 로고    scopus 로고
    • Cross-regulation of beta-catenin-LEF/TCF and retinoid signalling pathways
    • Dec 2
    • Easwaran V, Pishvaian M, Salimuddin, et al. Cross-regulation of beta-catenin-LEF/TCF and retinoid signalling pathways. Curr Biol 1999 Dec 2; 9 (23): 1415-1418
    • (1999) Curr Biol , vol.9 , Issue.23 , pp. 1415-1418
    • Easwaran, V.1    Salimuddin, P.M.2
  • 87
    • 3042777393 scopus 로고    scopus 로고
    • Late neuro-cognitive sequelae in survivors of brain tumours in childhood
    • Mulhern RK, Merchant TE, Gajjar A, et al. Late neuro-cognitive sequelae in survivors of brain tumours in childhood. Lancet Oncol 2004; 5 (7): 399-408
    • (2004) Lancet Oncol , vol.5 , Issue.7 , pp. 399-408
    • Mulhern, R.K.1    Merchant, T.E.2    Gajjar, A.3
  • 88
    • 8544275303 scopus 로고    scopus 로고
    • Long-term effects of radiation therapy on cog-nitive and endocrine function in children with leukemia and brain tumors
    • Duffner P. Long-term effects of radiation therapy on cog-nitive and endocrine function in children with leukemia and brain tumors. Neurologist 2004; 10 (6): 293-310
    • (2004) Neurologist , vol.10 , Issue.6 , pp. 293-310
    • Duffner, P.1
  • 89
    • 0025327476 scopus 로고
    • The treatment of medulloblastoma: Results of a prospective randomized trial of radiation therapy with and without CCNU, vin-cristine, and prednisone
    • Evans AE, Jenkin RD, Sposto R, et al. The treatment of medulloblastoma: results of a prospective randomized trial of radiation therapy with and without CCNU, vin-cristine, and prednisone. J Neurosurg 1990; 72 (4): 572-582
    • (1990) J Neurosurg , vol.72 , Issue.4 , pp. 572-582
    • Evans, A.E.1    Jenkin, R.D.2    Sposto, R.3
  • 90
    • 0025365252 scopus 로고
    • Adjuvant chemotherapy for medulloblastoma: The first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I)
    • Tait DM, Thornton-Jones H, Bloom HJ, et al. Adjuvant chemotherapy for medulloblastoma: the first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I). Eur J Cancer 1990; 26 (4): 464-469
    • (1990) Eur J Cancer , vol.26 , Issue.4 , pp. 464-469
    • Tait, D.M.1    Thornton-Jones, H.2    Bloom, H.J.3
  • 91
    • 0037842140 scopus 로고    scopus 로고
    • Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study
    • Apr 15
    • Taylor RE, Bailey CC, Robinson K, et al. Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study. J Clin Oncol 2003 Apr 15; 21 (8): 1581-1591
    • (2003) J Clin Oncol , vol.21 , Issue.8 , pp. 1581-1591
    • Taylor, R.E.1    Bailey, C.C.2    Robinson, K.3
  • 92
    • 0033056823 scopus 로고    scopus 로고
    • Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group study
    • Packer RJ, Goldwein JW, Nicholson HS, et al. Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: a Children's Cancer Group study. J Clin Oncol 1999; 17: 2127-2136
    • (1999) J Clin Oncol , vol.17 , pp. 2127-2136
    • Packer, R.J.1    Goldwein, J.W.2    Nicholson, H.S.3
  • 93
    • 0024331926 scopus 로고
    • Pre-irradiation chemotherapy for infants and children with medullo-blastoma: A preliminary report
    • Kretschmar CS, Tarbell NJ, Kupsky W, et al. Pre-irradiation chemotherapy for infants and children with medullo-blastoma: a preliminary report. J Neurosurg 1989; 71 (6): 820-825
    • (1989) J Neurosurg , vol.71 , Issue.6 , pp. 820-825
    • Kretschmar, C.S.1    Tarbell, N.J.2    Kupsky, W.3
  • 94
    • 0027495426 scopus 로고
    • Preradia-tion chemotherapy in advanced medulloblastoma: A Pediatric Oncology Group pilot study
    • Mosijczuk AD, Nigro MA, Thomas PRM, et al. Preradia-tion chemotherapy in advanced medulloblastoma: a Pediatric Oncology Group pilot study. Cancer 1993; 72 (9): 2755-2762
    • (1993) Cancer , vol.72 , Issue.9 , pp. 2755-2762
    • Mosijczuk, A.D.1    Nigro, M.A.2    Thomas, P.R.M.3
  • 95
    • 0342614892 scopus 로고    scopus 로고
    • Post-operative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medullo-blastoma in childhood: Results of the German prospective randomized trial HIT'91
    • Kortmann R-D, Kuhl J, Timmermann B, et al. Post-operative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medullo-blastoma in childhood: results of the German prospective randomized trial HIT'91. Int J Radiat Oncol Biol Phys 2000; 46 (2): 269-279
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , Issue.2 , pp. 269-279
    • Kortmann, R.-D.1    Kuhl, J.2    Timmermann, B.3
  • 96
    • 0014083105 scopus 로고
    • Response to medulloblastoma to vincristine sulfate: A case report
    • May 1
    • Lampkin BC, Mauer AM, McBride BH. Response to medulloblastoma to vincristine sulfate: a case report. Pediatrics 1967 May 1; 39 (5): 761-763
    • (1967) Pediatrics , vol.39 , Issue.5 , pp. 761-763
    • Lampkin, B.C.1    Mauer, A.M.2    McBride, B.H.3
  • 97
    • 0019471767 scopus 로고
    • Pharmacokinetics of vincristine in the cerebrospinal fluid of humans
    • Jackson Jr D, Sethi V, Spurr C, et al. Pharmacokinetics of vincristine in the cerebrospinal fluid of humans. Cancer Res 1981; 41: 1466-1468
    • (1981) Cancer Res , vol.41 , pp. 1466-1468
    • Jackson Jr, D.1    Sethi, V.2    Spurr, C.3
  • 98
    • 0037086460 scopus 로고    scopus 로고
    • Cerebrospinal fluid concentrations of vincristine after bolus intravenous dosing
    • Kellie SJ, Barbaric D, Koopmans P, et al. Cerebrospinal fluid concentrations of vincristine after bolus intravenous dosing. Cancer 2002; 94 (6): 1815-1820
    • (2002) Cancer , vol.94 , Issue.6 , pp. 1815-1820
    • Kellie, S.J.1    Barbaric, D.2    Koopmans, P.3
  • 99
    • 0025649742 scopus 로고
    • Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa
    • Packer RJ. Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa. Ann Neurol 1990; 28: 823-828
    • (1990) Ann Neurol , vol.28 , pp. 823-828
    • Packer, R.J.1
  • 100
    • 0019776955 scopus 로고
    • High-dose cyclophosphamide chemo-therapy for recurrent CNS tumors in children
    • Allen JC, Helson L. High-dose cyclophosphamide chemo-therapy for recurrent CNS tumors in children. J Neuro-surg 1981; 55: 749-756
    • (1981) J Neuro-surg , vol.55 , pp. 749-756
    • Allen, J.C.1    Helson, L.2
  • 101
    • 0028982811 scopus 로고
    • Cyclophosphamide in combination with sargramostim for treatment of recurrent medulloblastoma
    • Moghrabi A, Fuchs H, Brown M, et al. Cyclophosphamide in combination with sargramostim for treatment of recurrent medulloblastoma. Med Pediatr Oncol 1995; 25 (3): 190-196
    • (1995) Med Pediatr Oncol , vol.25 , Issue.3 , pp. 190-196
    • Moghrabi, A.1    Fuchs, H.2    Brown, M.3
  • 102
    • 34648828209 scopus 로고    scopus 로고
    • Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors
    • Nicholson HS, Kretschmar CS, Krailo M, et al. Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors. Cancer 2007; 110 (7): 1542-1550
    • (2007) Cancer , vol.110 , Issue.7 , pp. 1542-1550
    • Nicholson, H.S.1    Kretschmar, C.S.2    Krailo, M.3
  • 103
    • 0028080028 scopus 로고
    • Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy
    • Packer RJ, Sutton LN, Elterman RD, et al. Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy. J Neuro-surg 1994; 81: 690-698
    • (1994) J Neuro-surg , vol.81 , pp. 690-698
    • Packer, R.J.1    Sutton, L.N.2    Elterman, R.D.3
  • 104
    • 0023134873 scopus 로고
    • Carboplatin and re-current childhood brain tumors
    • Mar 1
    • Allen JC, Walker R, Luks E, et al. Carboplatin and re-current childhood brain tumors. J Clin Oncol 1987 Mar 1; 5 (3): 459-463
    • (1987) J Clin Oncol , vol.5 , Issue.3 , pp. 459-463
    • Allen, J.C.1    Walker, R.2    Luks, E.3
  • 105
    • 0025689697 scopus 로고
    • Carboplatin in childhood brain tumors: A Children's Cancer Study Group Phase II trial
    • Gaynon PS, Ettinger LJ, Baum ES, et al. Carboplatin in childhood brain tumors: a Children's Cancer Study Group Phase II trial. Cancer 1990; 66 (12): 2465-2469
    • (1990) Cancer , vol.66 , Issue.12 , pp. 2465-2469
    • Gaynon, P.S.1    Ettinger, L.J.2    Baum, E.S.3
  • 106
    • 0028821586 scopus 로고
    • Carboplatin in childhood medulloblastoma/PNET: Feasibility of an in vivo sensitivity test in an "up-front" study
    • Mastrangelo R, Lasorella A, Riccardi R, et al. Carboplatin in childhood medulloblastoma/PNET: feasibility of an in vivo sensitivity test in an "up-front" study. Med Ped Oncol 1995; 24 (3): 188-196
    • (1995) Med Ped Oncol , vol.24 , Issue.3 , pp. 188-196
    • Mastrangelo, R.1    Lasorella, A.2    Riccardi, R.3
  • 107
    • 0030964511 scopus 로고    scopus 로고
    • Treatment of stan-dard risk medulloblastoma with craniospinal irradiation, carboplatin, and vincristine
    • Dec
    • Bergman I, Jakacki RI, Heller G, et al. Treatment of stan-dard risk medulloblastoma with craniospinal irradiation, carboplatin, and vincristine. Med Pediatr Oncol 1997 Dec; 29 (6): 563-567
    • (1997) Med Pediatr Oncol , vol.29 , Issue.6 , pp. 563-567
    • Bergman, I.1    Jakacki, R.I.2    Heller, G.3
  • 109
    • 33750503089 scopus 로고    scopus 로고
    • Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroecto-dermal tumors, and atypical teratoid rhabdoid tumors
    • Fouladi M, Blaney SM, Poussaint TY, et al. Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroecto-dermal tumors, and atypical teratoid rhabdoid tumors. Cancer 2006; 107 (9): 2291-2297
    • (2006) Cancer , vol.107 , Issue.9 , pp. 2291-2297
    • Fouladi, M.1    Blaney, S.M.2    Poussaint, T.Y.3
  • 110
    • 0009851296 scopus 로고
    • Medullo-blastoma (MBL): Evaluation of the effectiveness of pre-radiation (RT) chemotherapy (CT) [abstract]
    • Fossati-Bellani F, Tesoro-Tess JD, Ballerini E. Medullo-blastoma (MBL): evaluation of the effectiveness of pre-radiation (RT) chemotherapy (CT) [abstract]. Med Ped Oncol 1990; 18: 361
    • (1990) Med Ped Oncol , vol.18 , pp. 361
    • Fossati-Bellani, F.1    Tesoro-Tess, J.D.2    Ballerini, E.3
  • 111
    • 0023935110 scopus 로고
    • Preradiation high-dose in-travenous methotrexate with leucovorin rescue for untreated primary childhood brain tumors
    • Apr 1
    • Allen JC, Walker R, Rosen G. Preradiation high-dose in-travenous methotrexate with leucovorin rescue for untreated primary childhood brain tumors. J Clin Oncol 1988 Apr 1; 6 (4): 649-653
    • (1988) J Clin Oncol , vol.6 , Issue.4 , pp. 649-653
    • Allen, J.C.1    Walker, R.2    Rosen, G.3
  • 112
    • 0029920921 scopus 로고    scopus 로고
    • An inten-sive multiagent chemotherapy regimen for brain tumours occurring in very young children
    • Mar 1
    • Lashford L, Campbell R, Gattamaneni H, et al. An inten-sive multiagent chemotherapy regimen for brain tumours occurring in very young children. Arch Dis Child 1996 Mar 1; 74 (3): 219-223
    • (1996) Arch Dis Child , vol.74 , Issue.3 , pp. 219-223
    • Lashford, L.1    Campbell, R.2    Gattamaneni, H.3
  • 113
    • 16644383428 scopus 로고    scopus 로고
    • Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma
    • Dec 15
    • Chi SN, Gardner SL, Levy AS, et al. Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma. J Clin Oncol 2004 Dec 15; 22 (24): 4881-4887
    • (2004) J Clin Oncol , vol.22 , Issue.24 , pp. 4881-4887
    • Chi, S.N.1    Gardner, S.L.2    Levy, A.S.3
  • 114
    • 0031983154 scopus 로고    scopus 로고
    • Intensive chemo-therapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors
    • Jan 1
    • Mason W, Grovas A, Halpern S, et al. Intensive chemo-therapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors. J Clin Oncol 1998 Jan 1; 16 (1): 210-221
    • (1998) J Clin Oncol , vol.16 , Issue.1 , pp. 210-221
    • Mason, W.1    Grovas, A.2    Halpern, S.3
  • 115
    • 0032780661 scopus 로고    scopus 로고
    • Topotecan for the treatment of recurrent or progressive central nervous system tumors: A Pediatric Oncology Group phase II study
    • Kadota RP, Stewart CF, Horn M, et al. Topotecan for the treatment of recurrent or progressive central nervous system tumors: a Pediatric Oncology Group phase II study. J Neurooncol 1999; 43 (1): 43-47
    • (1999) J Neurooncol , vol.43 , Issue.1 , pp. 43-47
    • Kadota, R.P.1    Stewart, C.F.2    Horn, M.3
  • 116
    • 8944222113 scopus 로고    scopus 로고
    • Phase II evalua-tion of topotecan for pediatric central nervous system tumors
    • Blaney SM, Phillips PC, Packer RJ, et al. Phase II evalua-tion of topotecan for pediatric central nervous system tumors. Cancer 1996; 78 (3): 527-531
    • (1996) Cancer , vol.78 , Issue.3 , pp. 527-531
    • Blaney, S.M.1    Phillips, P.C.2    Packer, R.J.3
  • 117
    • 0035873928 scopus 로고    scopus 로고
    • Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medullo-blastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: Results of a collaborative study
    • May 15
    • Strother D, Ashley D, Kellie SJ, et al. Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medullo-blastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: results of a collaborative study. J Clin Oncol 2001 May 15; 19 (10): 2696-2704
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2696-2704
    • Strother, D.1    Ashley, D.2    Kellie, S.J.3
  • 118
    • 4344566362 scopus 로고    scopus 로고
    • Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor
    • Aug 15
    • Stewart CF, Iacono LC, Chintagumpala M, et al. Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor. J Clin Oncol 2004 Aug 15; 22 (16): 3357-3365
    • (2004) J Clin Oncol , vol.22 , Issue.16 , pp. 3357-3365
    • Stewart, C.F.1    Iacono, L.C.2    Chintagumpala, M.3
  • 119
    • 0025057933 scopus 로고
    • Preirradiation cisplatin and etoposide in the treatment of high-risk me-dulloblastoma and other malignant embryonal tumors of the central nervous system: A phase II study
    • Feb 1
    • Kovnar EH, Kellie SJ, Horowitz ME, et al. Preirradiation cisplatin and etoposide in the treatment of high-risk me-dulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study. J Clin Oncol 1990 Feb 1; 8 (2): 330-336
    • (1990) J Clin Oncol , vol.8 , Issue.2 , pp. 330-336
    • Kovnar, E.H.1    Kellie, S.J.2    Horowitz, M.E.3
  • 120
    • 8944252806 scopus 로고    scopus 로고
    • Response of recurrent medulloblastoma to low-dose oral etoposide
    • Ashley DM, Meier L, Kerby T, et al. Response of recurrent medulloblastoma to low-dose oral etoposide. J Clin Oncol 1996; 14 (6): 1922-1927
    • (1996) J Clin Oncol , vol.14 , Issue.6 , pp. 1922-1927
    • Ashley, D.M.1    Meier, L.2    Kerby, T.3
  • 121
    • 77949648463 scopus 로고    scopus 로고
    • A phase I/II feasibility study of oral etoposide given concurrently with radiotherapy followed with dose-intensive adjuvant chemotherapy for children with newly diagnosed high-risk medulloblastoma COG P9631 [abstract]
    • Moghrabi A, Hershon L, Rousseau P, et al. A phase I/II feasibility study of oral etoposide given concurrently with radiotherapy followed with dose-intensive adjuvant chemotherapy for children with newly diagnosed high-risk medulloblastoma COG P9631 [abstract]. Neuro-oncology 2008; 10 (3): 476.
    • (2008) Neuro-oncology , vol.10 , Issue.3 , pp. 476
    • Moghrabi, A.1    Hershon, L.2    Rousseau, P.3
  • 122
    • 77949647952 scopus 로고    scopus 로고
    • 29 Jun-2 Jul Chicago (IL)
    • 13th Annual ISPNO Meeting; 29 Jun-2 Jul 2008; Chicago (IL)
    • (2008) 13th Annual ISPNO Meeting
  • 123
    • 0030054134 scopus 로고    scopus 로고
    • Will high-dose chemotherapy followed by autologous bone marrow transplantation supplant cranio-spinal irradiation in young children treated for medulloblastoma?
    • Dupuis-Girod S, Hartmann O, Benhamou E, et al. Will high-dose chemotherapy followed by autologous bone marrow transplantation supplant cranio-spinal irradiation in young children treated for medulloblastoma? J Neuro-Oncol 1996; 27: 87-98
    • (1996) J Neuro-Oncol , vol.27 , pp. 87-98
    • Dupuis-Girod, S.1    Hartmann, O.2    Benhamou, E.3
  • 124
    • 0030050173 scopus 로고    scopus 로고
    • High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: A pilot Pediatric Oncology Group study
    • Mahoney Jr DH, Strother D, Camitta B, et al. High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: a pilot Pediatric Oncology Group study. J Clin Oncol 1996; 14: 382-388
    • (1996) J Clin Oncol , vol.14 , pp. 382-388
    • Mahoney Jr, D.H.1    Strother, D.2    Camitta, B.3
  • 125
    • 17744418136 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors
    • Graham ML, Herndon 2nd JE, Casey JR, et al. High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. J Clin Oncol 1997; 15 (5): 1814-1823
    • (1997) J Clin Oncol , vol.15 , Issue.5 , pp. 1814-1823
    • Graham, M.L.1    Herndon II, J.E.2    Casey, J.R.3
  • 126
    • 0031861022 scopus 로고    scopus 로고
    • Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors
    • Guruangan S, Dunkel IJ, Goldman S, et al. Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors. J Clin Oncol 1998; 16: 2486-2493
    • (1998) J Clin Oncol , vol.16 , pp. 2486-2493
    • Guruangan, S.1    Dunkel, I.J.2    Goldman, S.3
  • 127
    • 0031982606 scopus 로고    scopus 로고
    • High-dose carbo-platin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma
    • Dunkel IJ, Boyett JM, Yates A, et al. High-dose carbo-platin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. J Clin Oncol 1998; 16 (1): 222-228
    • (1998) J Clin Oncol , vol.16 , Issue.1 , pp. 222-228
    • Dunkel, I.J.1    Boyett, J.M.2    Yates, A.3
  • 128
    • 0032797110 scopus 로고    scopus 로고
    • Long-term in-tellectual outcome in children with posterior fossa tumors according to radiation doses and volumes
    • Grill J, Renaux VK, Bulteau C, et al. Long-term in-tellectual outcome in children with posterior fossa tumors according to radiation doses and volumes. Int J Radiat Oncol Biol Phys 1999; 45 (1): 137-145
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , Issue.1 , pp. 137-145
    • Grill, J.1    Renaux, V.K.2    Bulteau, C.3
  • 129
    • 0035863507 scopus 로고    scopus 로고
    • Growth hormone replacement therapy in children with medulloblastoma: Use and effect on tumor control
    • Packer RJ, Boyett JM, Janss AJ, et al. Growth hormone replacement therapy in children with medulloblastoma: use and effect on tumor control. J Clin Oncol 2001; 19: 480-487
    • (2001) J Clin Oncol , vol.19 , pp. 480-487
    • Packer, R.J.1    Boyett, J.M.2    Janss, A.J.3
  • 130
    • 0036643969 scopus 로고    scopus 로고
    • Hypothyroidism in children with medullo-blastoma: A comparison of 3600 and 2340 cGy cranio-spinal radiotherapy
    • Paulino AC. Hypothyroidism in children with medullo-blastoma: a comparison of 3600 and 2340 cGy cranio-spinal radiotherapy. Int J Radiat Oncol Biol Phys 2002; 53 (3): 543-547
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , Issue.3 , pp. 543-547
    • Paulino, A.C.1
  • 131
    • 10744227370 scopus 로고    scopus 로고
    • Final height and body mass index among adult survivors of childhood brain cancer: Childhood Cancer Survivor Study
    • Oct 1
    • Gurney JG, Ness KK, Stovall M, et al. Final height and body mass index among adult survivors of childhood brain cancer: Childhood Cancer Survivor Study. J Clin Endocrinol Metab 2003 Oct 1; 88 (10): 4731-4739
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.10 , pp. 4731-4739
    • Gurney, J.G.1    Ness, K.K.2    Stovall, M.3
  • 132
    • 0036498884 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for pediatric medulloblastoma: Early report on the reduction of ototoxicity
    • Huang E, Teh BS, Strother DR, et al. Intensity-modulated radiation therapy for pediatric medulloblastoma: early report on the reduction of ototoxicity. Int J Radiat Oncol Biol Phys 2002; 52 (3): 599-605
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , Issue.3 , pp. 599-605
    • Huang, E.1    Teh, B.S.2    Strother, D.R.3
  • 133
    • 0032054645 scopus 로고    scopus 로고
    • The use of 3D conformal radiotherapy (3D CRT) to spare the cochlea in patients with medulloblastoma
    • Fukunaga-Johnson N, Sandler HM, Marsh R, et al. The use of 3D conformal radiotherapy (3D CRT) to spare the cochlea in patients with medulloblastoma. Int J Radiat Oncol Biol Phys 1998; 41 (1): 77-82
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , Issue.1 , pp. 77-82
    • Fukunaga-Johnson, N.1    Sandler, H.M.2    Marsh, R.3
  • 134
    • 33644848462 scopus 로고    scopus 로고
    • Ototoxicity in children receiving platinum chemotherapy: Underestimating a commonly occurring toxicity that may influence academic and social development
    • Knight KR, Kraemer DF, Neuwelt EA. Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development. J Clin Oncol 2005; 23 (34): 8588-8596
    • (2005) J Clin Oncol , vol.23 , Issue.34 , pp. 8588-8596
    • Knight, K.R.1    Kraemer, D.F.2    Neuwelt, E.A.3
  • 135
    • 4143081483 scopus 로고    scopus 로고
    • Com-bined histopathological and molecular cytogenetic stratification of medulloblastoma patients
    • Aug 15
    • Lamont JM, McManamy CS, Pearson AD, et al. Com-bined histopathological and molecular cytogenetic stratification of medulloblastoma patients. Clin Cancer Res 2004 Aug 15; 10 (16): 5482-5493
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5482-5493
    • Lamont, J.M.1    McManamy, C.S.2    Pearson, A.D.3


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