Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: Results of a collaborative study

Journal of Clinical Oncology

Volumn 19, Issue 10, 2001, Pages 2696-2704

  Strother, Douglas ^b   Ashley, David ^b   Kellie, Stewart J ^b   Patel, Akta ^b   Jones Wallace, Dana ^b   Thompson, Stephen ^b   Heideman, Richard ^b   Benaim, Ely ^b   Krance, Robert ^b   Bowman, Laura ^b   Gajjar, Amar ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; MESNA; TOPOTECAN; VINCRISTINE;

ADOLESCENT; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CARDIOTOXICITY; CHILD; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; FEMALE; FEVER; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HYPOTENSION; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; NAUSEA; NEUROECTODERM TUMOR; NEUTROPENIA; PRIORITY JOURNAL; SKULL IRRADIATION; SURVIVAL RATE; VOMITING;

EID: 0035873928     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.10.2696     Document Type: Article

References (46)

1. Legros M, Dauplat J, Fleury J, et al: High-dose chemotherapy with hematopoietic rescue in patients with stage III to IV ovarian cancer: Long term results. J Clin Oncol 15:1302-1308, 1997
2. Amman KH, Rowlings PA, Vaughan WP, et al: High-dose chemotherapy with autologous hematopoietic stem-cell support for breast cancer in North America. J Clin Oncol 15:1870-1879, 1997
3. Ayash LJ, Eilas A, Ibrahim J, et al: High-dose multimodality therapy with autologous stem-cell support for stage IIIB breast carcinoma. J Clin Oncol 16:1000-1007, 1998
4. Stadtmauer EA, O'Neill A, Goldsiein LJ, et al: Conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer: Philadelphia Bone Marrow Transplant Group. N Engl J Med 342:1069-1076, 2000
5. Stoppa AM, Bouabdallah C, Chabannon C, et al: Intensive sequential chemotherapy with repeated blood stem-cell support for untreated poor-prognosis non-Hodgkin's lymphoma. J Clin Oncol 15:1722-1729, 1997
6. Santini G, Salvagno L, Leoni P, et al: VACOP-B versus VACOP-B plus autologous bone marrow transplantation for advanced diffuse non-Hodgkin's lymphoma: Results of a prospective randomized trial by the Non-Hodgkin's Lymphoma Cooperative Study Group. J Clin Oncol 16:2796-2802, 1998
7. Mounier N, Haioun C, Cole BF, et al: Quality of life-adjusted survival analysis of high-dose therapy with autologous bone marrow transplantation versus sequential chemotherapy for patients with aggressive lymphoma in first complete remission: Groupe d'Etude les Lymphomes de l'Adulte (GELA). Blood 95:3687-3692, 2000
8. Desikan R, Barlogie B, Sawyer J, et al: Results of high-dose therapy for 1000 patients with multiple myeloma: Durable complete remissions and superior survival in the absence of chromosome 13 abnormalities. Blood 95:4008-4010, 2000
9. Bokemeyer C, Franzke A, Hartman JT, et al: A phase I/II study of sequential, dose-escalated, high dose ifosfamide plus doxorubicin with peripheral blood stem cell support for the treatment of patients with advanced soft tissue sarcomas. Cancer 80:1221-1227, 1997
10. Matthay KK, Villablanca JG, Seeger RC, et al: Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid: Children's Cancer Group. N Engl J Med 341:1165-1173, 1999
11. Grupp SA, Stern JW, Bunin N, et al: Tandem high-dose therapy in rapid sequence for children with high-risk neuroblastoma. J Clin Oncol 18:2567-2575, 2000
12. Baker KS, Gordon BG, Gross TG, et al: Autologous hematopoietic stem-cell transplantation for relapsed or refractory Hodgkin's disease in children and adolescents. J Clin Oncol 17:825-831, 1999
13. Horowitz ME, Kinsella TJ, Wexler LH, et al: Total-body irradiation and autologous bone marrow transplant in the treatment of high-risk Ewing's sarcoma and rhabdomyosarcoma. J Clin Oncol 11:1911-1918, 1993
14. Santana VM, Schell MJ, Williams R, et al: Escalating sequential high-dose carboplatin and etoposide with autologous marrow support in children with relapsed solid tumors. Bone Marrow Transplant 10:457-462, 1992
15. Finlay JL, Goldman S, Wong MC, et al: Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors: The Children's Cancer Group. J Clin Oncol 14:2495-2503, 1996
16. Graham ML, Herndon JE II, Casey JR, et al: High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. J Clin Oncol 15:1814-1823, 1997
17. Dunkel I, Boyett JM, Yates A, et al: High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma: Children's Cancer Group. J Clin Oncol 16:222-228, 1998
18. Gururangan S, Dunkel IJ, Goldman S, et al: Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors. J Clin Oncol 16:2486-2493, 1998
19. Mahoney DH, Strother D, Camilla B, et al: High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: A pilot Pediatric Oncology Group study. J Clin Oncol 14:382-388, 1996
20. Johnson DB, Thompson JM, Corwin JA, et al: Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation. J Clin Oncol 5:783-789, 1987
21. Heideman RL, Douglass EC, Krance RA, et al: High-dose chemotherapy and autologous bone marrow rescue followed by interstitial and external-beam radiotherapy in newly diagnosed pediatric malignant gliomas. J Clin Oncol 11:1458-1465, 1993
22. Kalita C, Hartmann O, Demeocq F, et al: High-dose busulfan and thiotepa with autologous bone marrow transplantation in childhood malignant brain tumors: A phase II study. Bone Marrow Transplant 9:227-233, 1992
23. Bouffet E, Mottolese C, Jouvet A, et al: Etoposide and thiotepa followed by autologous bone marrow transplantation in children and young adults with high-grade gliomas. Eur J Cancer 33:91-95, 1997
24. Papadopoulos KP, Garvin JH, Fetell M, et al: High-dose thiotepa and etoposide-based regimens with autologous hematopoietic support for high-risk or recurrent CNS tumors in children and adults. Bone Marrow Transplant 33:661-667, 1998
25. Dupuis-Girod S, Hartman O, Benhamou E, et al: Will high dose chemotherapy followed by autologous bone marrow transplantation supplant cranio-spinal irradiation in young children treated for medulloblastoma? J Neurooncol 27:87-98, 1996
26. Mason WP, Grovas A, Halpern S, et al: Intensive chemotherapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors. J Clin Oncol 16:210-221, 1998
27. Gajjar A, Kuhl J, Epelman S, et al: Chemotherapy of medulloblastoma. Childs Nerv Syst 15:554-562, 1999
28. Allen JC, Helson L: High-dose cyclophosphamide chemotherapy for recurrent CNS tumors in children. J Neurosurg 55:749-756, 1981
29. Friedman HS, Mahaley MS Jr, Schold SC Jr, et al: Efficacy of vincristine and cyclophosphamide in the therapy of recurrent medulloblastoma. Neurosurgery 18:335-340, 1986
30. Abrahamsen TG, Lange BJ, Packer RJ, et al: A phase I and II trial of dose-intensified cyclophosphamide and GM-CSF in pediatric malignant brain tumors. J Pediatr Hematol Oncol 17:134-139, 1995
31. Lachance DH, Oette D, Schold SC Jr, et al: Dose escalation trial of cyclophosphamide with sargramostim in the treatment of central nervous system (CNS) neoplasms. Med Pediatr Oncol 24:241-247, 1995
32. Skipper HE: Criteria associated with destruction of leukemic and solid tumor cells in animals. Cancer Res 27:2636-2645, 1967
33. Baynes RD, Dansey RD, Klein JL, et al: High-dose chemotherapy and autologous stem cell transplantation for breast cancer. Cancer Invest 18:440-455, 2000
34. Frei E III, Canellos GP: Dose: A critical factor in cancer chemotherapy. Am J Med 69:585-594, 1980
35. Hryniuk W, Levine MN: Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer. J Clin Oncol 4:1162-1170, 1986
36. Schilder RJ, Johnson S, Gallo J, et al: Phase I trial of multiple cycles of high-dose chemotherapy supported by autologous peripheral-blood stem cells. J Clin Oncol 17:2198-2207, 1999
37. Pettengell R, Woll PJ, Thatcher N, et al. Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood. J Clin Oncol 13:148-156, 1995
38. Shea TC, Mason JR, Storniolo AM, et al: Sequential cycles of high-dose carboplatin administered with recombinant human granulocyte-macrophage colony-stimulating factor and repeated infusions of autologous peripheral-blood progenitor cells: A novel and effective method for delivering multiple courses of dose-intensive therapy. J Clin Oncol 10:464-473, 1992
39. Jakacki RI, Jamison C, Heifetz SA, et al: Feasibility of sequential high-dose chemotherapy and peripheral blood stem cell support for pediatric central nervous system malignancies. Med Pediatr Oncol 29:553-559, 1997
40. Friedman HS, Oakes JW, Bigner SH, et al: Medulloblastoma: Tumor biological and clinical perspectives. J Neurooncol 11:1-15, 1991
41. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
42. Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized clinical trials requiring prolonged observation of each patient, II: Analysis and examples. Br J Cancer 35:1-39, 1977
43. Packer RJ, Goldwein J, Nicholson HS, et al: Treatment of children with medulloblastoma with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study. J Clin Oncol 17:2127-2136, 1999
44. Tarbell NJ, Friedman H, Kepner J, et al: Outcome for children with high stage medulloblastoma: Results of the Pediatric Oncology Group 9031. Int J Radiat Oncol Biol Phys 48:134, 20000 (abstr)
45. Cohen BH, Zweidler P, Goldwein JW, et al: Ototoxic effects of cisplatin in children with brain tumors. Pediatr Neurosurg 16:292-296, 1990-91
46. Freilich RJ, Kraus DH, Budnick AS, et al: Hearing loss in children with brain tumors treated with cisplatin and carboplatin-based high-dose chemotherapy with autologous bone marrow rescue. Med Pediatr Oncol 26:95-100, 1996