Intensive chemotherapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors

Journal of Clinical Oncology

Volumn 16, Issue 1, 1998, Pages 210-221

  Mason, Warren P ^a   Grovas, Alfred ^a   Halpern, Steven ^a   Dunkel, Ira J ^a   Garvin, James ^a   Heller, Glenn ^a   Rosenblum, Marc ^a   Gardner, Sharon ^a   Lyden, David ^a   Sands, Stephen ^a   Puccetti, Diane ^a   Lindsley, Karen ^a   Merchant, Thomas E ^a   O'Malley, Bernard ^a   Bayer, Lisa ^a   Petriccione, Mary McElwain ^a   Allen, Jeffrey ^a   Finlay, Jonathan L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; THIOTEPA; VINCRISTINE;

ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW RESCUE; BONE MARROW SUPPRESSION; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; DRUG TOLERABILITY; ELECTROLYTE DISTURBANCE; FEMALE; HEARING LOSS; HUMAN; HYPERPIGMENTATION; INFECTION; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; NAUSEA; NEUTROPENIA; PRESCHOOL CHILD; PRIORITY JOURNAL; REMISSION; SEPSIS; THROMBOCYTOPENIA; TREATMENT OUTCOME; VOMITING;

EID: 0031983154     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.1.210     Document Type: Article

References (51)

1. Young JL, Ries LG, Silverberg E, et al: Cancer incidence, survival and mortality for children under 15 years of age. Cancer 58:598-602, 1985 (suppl)
2. Duffner PK, Cohen ME, Myers MH, et al: Survival of children with brain tumors: SEER program, 1973-1980. Neurology 36:597-601, 1986
3. Allen JC, Bloom J, Ertel I, et al: Brain tumors in children: Current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease. Semin Oncol 13:110-122, 1986
4. Evans AE, Jenkin RDT, Sposto R, et al: The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone. J Neurosurg 72:572-582, 1990
5. Packer, RJ, Meadows AT, Rorke LB, et al: Long-term sequellae of cancer treatment on the central nervous system in childhood. Med Pediatr Oncol 15:241-253, 1987
6. Meadows AT, Massari DJ, Fergusson J, et al: Declines in IQ scores and cognitive dysfunctions in children with acute lymphocytic leukemia treated with cranial irradiation. Lancet 2:1015-1018, 1981
7. Spunberg JJ, Chang CH, Goldman M, et al: Quality of long-term survival following irradiation for intracranial tumors in children under the age of two. Int J Radiat Oncol Biol Phys 7:727-736, 1980
8. Suc E, Kalifa C, Brauner R, et al: Brain tumors under the age of three. The price of survival. Acta Neurochir (Wien) 106:93-98, 1990
9. Ellenberg L, McComb JG, Siegel SE, et al: Factors affecting intellectual outcome in pediatric brain tumor patients. Neurosurgery 21:638-644, 1987
10. Pendergrass TW, Milstein JM, Geyer JR, et al: Eight drugs in one day chemotherapy for brain tumors: Experience in 107 children and rationale for preradiation chemotherapy. J Clin Oncol 5:1221-1231, 1987
11. Duffner PK, Horowitz ME, Krischer JP, et al: Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med 328:1725-1731, 1993
12. Geyer JR, Zeltzer PM, Boyett JM, et al: Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: A report from the Childrens Cancer Group. J Clin Oncol 12:1607-1615, 1994
13. White L, Johnston H, Jones R, et al: Postoperative chemotherapy without radiation in young children with malignant non-astrocytic brain tumors. A report from this he Australia and New Zealand Childhood Cancer Study Group. Cancer Chemother Pharmacol 32:403-406, 1993
14. Calvert A, Newell D, Gumbrel L: Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol 7:1748-1756, 1989
15. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
16. Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II: Analysis and examples. Br J Cancer 35:1-39, 1977
17. Evans AE, Anderson JR, Lefkowitz-Boudreaux IB, et al: Adjuvant chemotherapy of childhood posterior fossa ependymoma: Craniospinal irradiation with or without adjuvant CCNU, vincristine, and prednisone: A Childrens Cancer Group trial. Med Pediatr Oncol 27:8-14, 1996
18. Finlay, JL, Boyett JM, Yates AJ, et al: Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. J Clin Oncol 13:112-123, 1995
19. Friedman HS, Krischer JP, Burger P, et al: Treatment of children with progressive or recurrent brain tumors with carboplatin or iproplatin: A Pediatric Oncology Group randomized phase II study. J Clin Oncol 10:249-256, 1992
20. Tait DM, Thornton-Jones H, Bloom HJG, et al: Adjuvant chemotherapy for medulloblastoma: The first multi-center controlled trial of the International Society of Pediatric Oncology (SIOP). Eur J Cancer 26:464-469, 1990
21. Gaynon PS, Ettinger LJ, Baum ES, et al: Carboplatin in childhood brain tumors. A Children's Cancer Study Group phase II trial. Cancer 66:2465-2469, 1990
22. Allen JC, Helson L, Jereb B: Preradiation chemotherapy for newly diagnosed childhood brain tumors. A modified phase II trial. Cancer 52:2001-2006, 1983
23. Finlay JL, August C, Packer R, et al: High-dose multi-agent chemotherapy followed by bone marrow 'rescue' for malignant astrocytomas of childhood and adolescence. J Neurooncol 9:239-248, 1990
24. x) with autologous marrow rescue (ABMR) in patients with recurrent medulloblastoma (MB)/primitive neuroectodermal tumors (PNET). Proc Am Soc Clin Oncol 13:176, 1994 (abstr)
25. Mahoney DH Jr, Strother D, Camilla B, et al: High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: A pilot Pediatric Oncology Group Study. J Clin Oncol 14:382-388, 1996
26. Kalifa C, Hartmann O, Demeocq F, et al: High-dose busulfan and ThioTEPA with autologous bone marrow transplantation in childhood malignant brain tumors: A phase II study. Bone Marrow Transplant 9:227-233, 1992
27. Tomita T, McLone, DG, Yasue M: Cerebral primitive neuroectodermal tumors in childhood. J Neurooncol 6:233-243, 1988
28. Gaffney CC, Sloane JP, Bradley NJ, et al: Primitive neuroectodermal tumors of the cerebrum. Pathology and treatment. J Neurooncol 3:23-33, 1985
29. Cohen BH, Zeltzer PM, Boyett JM, et al: Prognostic factors and treatment results for supratentorial primitive neuroectodermal tumors in children using radiation and chemotherapy: A Childrens Cancer Group randomized trial. J Clin Oncol 13:1687-1696, 1995
30. Jakacki RI, Zeltzer PM, Boyett JM, et al: Survival and prognostic factors following radiation and/or chemotherapy for primitive neuroectodermal tumors of the pineal region in infants and children: A report of the Childrens Cancer Group. J Clin Oncol 13:1377-1383, 1995
31. Duffner PK, Cohen ME, Kun L, et al: Prognostic factors in infants with ependymomas. Ann Neurol 38:546, 1995
32. Baram TZ, van Eys J, Dowell RE, et al: Survival and neurologic outcome of infants with medulloblastoma treated with surgery and MOPP chemotherapy. A preliminary report. Cancer 60:173-177, 1987
33. Kovalic JJ, Flaris N, Grigsby PW: Intracranial ependymoma long term outcome, patterns of failure. J Neurooncol 15:125-131, 1993
34. Goldwein JW, Corn BW, Finlay, JL, et al: Is craniospinal irradiation required to cure children with malignant (anaplastic) intracranial ependymomas? Cancer 67:2766-2771, 1991
35. Nazar GB, Hoffman HJ, Becker LE, et al: Infratentorial ependymomas in childhood: prognostic factors and treatment. J Neurosurg 72:408-417, 1990
36. Goldwein JW, Glauser TA, Packer RJ, et al: Recurrent intracranial ependymomas in children. Survival, patterns of failure, and prognostic factors. Cancer 66:557-563, 1990
37. Mason WP, Goldman S, Grovas A, et al: Intensive chemotherapy and autologous bone marrow reconstitution for children with new or recurrent ependymoma. Proc Am Soc Clin Oncol 14:145, 1995 (abstr)
38. Kahn AB, D'Souza BJ, Wharam MD, et al: Cisplatin therapy in recurrent childhood brain tumors. Cancer Treat Rep 66:2013-2020, 1982
39. Kovnar EH, Kellie SJ, Horowitz ME, et al: Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: A phase II study. J Clin Oncol 8:330-336, 1990
40. Lefkowitz IB, Packer RJ, Siegel KR, et al: Results of treatment of children with recurrent medulloblastoma/primitive neuroectodermal tumors with lomustine, cisplatin, and vincristine. Cancer 65:412-417, 1990
41. Strauss LC, Killmond TM, Carson BS, et al: Efficacy of postoperative chemotherapy using cisplatin plus etoposide in young children with brain tumors. Med Pediatr Oncol 19:16-21, 1991
42. Kedar A, Maria BL, Graham-Pole J, et al: High-dose chemotherapy with marrow reinfusion and hyperfractionated irradiation for children with high-risk brain tumors. Med Pediatr Oncol 23:428-436, 1994
43. Heideman RL, Douglass EC, Krance RA, et al: High-dose chemotherapy and autologous bone marrow rescue followed by interstitial and external-beam radiotherapy in newly diagnosed pediatric malignant gliomas. J Clin Oncol 11:1458-1465, 1993
44. Johnson DB, Thompson JM, Corwin JA, et al: Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation. J Clin Oncol 5:783-789, 1987
45. Silber J, Radcliffe J, Peckham V, et al: Whole-brain irradiation and decline in intelligence: The influence of dose and age on IQ score. J Clin Oncol 10:1390-1396, 1992
46. Radcliffe J, Bunin G, Sutton L, et al: Cognitive deficits in long-term survivors of childhood medulloblastoma and other non cortical tumors: Age dependent effects of whole brain radiation. Int J Development Neurosci 12:327-334, 1994
47. Copeland D, Moore B, Francis D, et al: Neuropsychological effects of chemotherapy on children with cancer: A longitudinal study. J Clin Oncol 14:2826-2835, 1996
48. Moore B, Ater J, Copeland D: Improved neuropsychological outcome in children with brain tumors diagnosed during infancy and treated without cranial irradiation. J Child Neurol 7:281-290, 1992
49. Cohen B, Packer R, Siegel K, et al: Brain tumors in children under 2 years: Treatment, survival and long-term prognosis. Pediatr Neurosurg 19:171-179, 1993
50. Dupuis-Girod S, Hartmann O, Benhamou E, et al: Will high dose chemotherapy followed by autologous bone marrow transplantation supplant cranio-spinal irradiation in young children treated for medulloblastoma? J Neurooncol 27:87-98, 1996
51. Torres CF, Rebsamen S, Silber JH, et al: Surveillance scanning of children with medulloblastoma. N Engl J Med 330:892-895, 1994