Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors

Journal of Clinical Oncology

Volumn 16, Issue 7, 1998, Pages 2486-2493

  Gururangan, Sridharon ^a   Dunkel, Ira J ^b   Goldman, Stewart ^b   Garvin, James H ^b   Rosenblum, Marc ^b   Boyett, James M ^b   Gardner, Sharon ^b   Merchant, Thomas E ^b   Gollamudi, Smitha ^b   Finlay, Jonathan L ^b  

^a CHILDREN S ONCOLOGY GROUP   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; IFOSFAMIDE; LOMUSTINE; METHOTREXATE; THIOTEPA; VINCRISTINE;

ARTICLE; BONE MARROW RESCUE; BRAIN TUMOR; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GLIOBLASTOMA; HUMAN; MALE; MEDULLOBLASTOMA; MINIMAL RESIDUAL DISEASE; MOUTH INFLAMMATION; NEUROECTODERM TUMOR; NEUTROPENIA; PANCYTOPENIA; PHARYNGITIS; PRIORITY JOURNAL; RECURRENT CANCER; TREATMENT INDICATION; TREATMENT OUTCOME;

EID: 0031861022     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1998.16.7.2486     Document Type: Article

References (35)

1. Torres CF, Rebsamen S, Silber JH, et al: Surveillance scanning of children with medulloblastoma. N Engl J Med 330:892-895, 1994
2. Belza MG, Donaldson SS, Steinberg GK, et al: Medulloblastoma: Freedom from relapse longer than 8 years - A therapeutic cure? J Neurosurg 75:575-582, 1991
3. Finlay JL, Boyett JM, Yates AJ, et al: Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. J Clin Oncol 13:112-123, 1995
4. Baram TZ, Van Eys J, Dowell RE, et al: Survival and neurologic outcome of infants with medulloblastoma treated with surgery and MOPP chemotherapy. Cancer 60:173-177, 1987
5. Geyer JR, Zeltzer PM, Boyett JM, et al. Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: A report from the Childrens Cancer Group. J Clin Oncol 12:1607-1615, 1994
6. Geyer JR, Finlay JL, Boyett JM, et al: Survival of infants with malignant gliomas. A report from the Childrens Cancer Group. Cancer 75:1045-1050, 1995
7. Gajjar A, Mulhern RK, Heideman RL, et al: Medulloblastoma in very young children: Outcome of definitive craniospinal irradiation following incomplete response to chemotherapy. J Clin Oncol 12:1212-1216, 1994
8. Hartsell WF, Gajjar A, Heideman RL, et al: Patterns of failure in children with medulloblastoma: Effects of preirradiation chemotherapy. Int J Radiat Oncol Biol Phys 39:15-24, 1997
9. Duffner PK, Horowitz ME, Krischer JP, et al: Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med 328: 1725-1731, 1993
10. Duffner PK, Krischer JP, Burger PC, et al: Treatment of infants with malignant gliomas: The Pediatric Oncology Group experience. J Neurooncol 28:245-256, 1996
11. Duffner PK, Cohen ME, Sanford RA, et al: Lack of efficacy of postoperative chemotherapy and delayed radiation in very young children with pineoblastoma. Med Pediatr Oncol 25:38-44, 1995
12. Dupuis-Girod S, Hartmann O, Benhamou E, et al: Will high-dose chemotherapy followed by autologous bone marrow transplantation supplant craniospinal irradiation in young children treated for medulloblastoma? J Neurooncol 27:87-98, 1996
13. Finlay JL, Goldman S, Wong MC, et al: Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. J Clin Oncol 14:2495-2503, 1996
14. Finlay JL, August C, Packer R, et al: High-dose multi-agent chemotherapy followed by bone marrow "rescue" for malignant astrocytomas of childhood and adolescence. J Neurooncol 9:239-248, 1990
15. Dunkel IJ, Boyett JM, Yates A, et al: High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. J Clin Oncol 16:222-228, 1998
16. Phillips GL, Wolff SN, Fay JW, et al: Intensive 1,3-Bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma. J Clin Oncol 4:639-645, 1986
17. Graham ML, Herndon JE, Casey JR, et al: High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. J Clin Oncol 15:1814-1823, 1997
18. Calvert AH, Newell DR, Gumbrell LA, et al: Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol 7:1748-1756, 1989
19. Newell DR, Pearson ADJ, Balmanno K, et al: Carboplatin pharmacokinetics in children: The development of a pediatric dosing formula. J Clin Oncol 11:2314-2323, 1993
20. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
21. Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 34:585-612, 1976
22. Rosenblum ML, Wheeler KT, Wilson CB, et al: In vitro evaluation of in vivo brain tumor chemotherapy with 1,3-Bis (2-chloroethyl)-1-nitrosourea. Cancer Res 35:1387-1391, 1975
23. Teicher BA, Holden SA, Eder JP, et al: Influence of schedule on alkylating agent cytotoxicity in vitro and in vivo. Cancer Res 49:5994-5998, 1989
24. Freidman HS, Colvin OM, Skapek SX, et al: Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents. Cancer Res 48:4189-4195, 1988
25. Gaynon PS, Ettinger LJ, Baum ES, et al: Carboplatin in childhood brain tumors. A Children's Cancer Study Group phase II trial. Cancer 66:2465-2469, 1990
26. Heideman RL, Cole DE, Balis F, et al: Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: Evidence for dose-dependent plasma clearance of thiotepa. Cancer Res 49:736-741, 1989
27. Heideman RL, Packer RJ, Reaman GH, et al: A phase II evaluation of thiotepa in pediatric central nervous system malignancies. Cancer 72:271-275, 1993
28. Wolfe SN, Fer MF, McKay CM, et al: High-dose VP-16 and autologous bone marrow transplantation for refractory malignancies: A phase I study. J Clin Oncol 1:701-705, 1983
29. Mahoney DH, Strother D, Camitta B, et al: High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: A pilot Pediatric Oncology Group study. J Clin Oncol 14:382-388, 1996
30. Finlay J: High-dose chemotherapy with autologous bone marrow rescue (HDCx + ABMR) improves survival of patients with recurrent malignant glioma (MG) compared with conventional or no chemotherapy. J Neurooncol 15:S8, 1993 (abstr)
31. Heideman RL, Douglass EC, Krance RA, et al: High-dose chemotherapy and autologous bone marrow rescue followed by interstitial and external-beam radiotherapy in newly diagnosed pediatric malignant gliomas. J Clin Oncol 11:1458-1465, 1993
32. Faulkner ED, Lindsley KL, Kher U, et al: High-dose chemotherapy with autologous marrow rescue for malignant brain tumors: Analysis of the impact of prior chemotherapy and craniospinal irradiation on hematopoeitic recovery. Bone Marrow Transplant 17:389-394, 1996
33. George D, Ginsberg J, Weingast R, et al: Multi-organ failure syndrome in patients undergoing myeloablative chemotherapy and autologous bone marrow rescue for malignant brain tumors. Exp Hematol 22:379, 1994 (abstr)
34. Biron P, Vial C, Chauvin F, et al: Strategy including surgery, high-dose BCNU followed by ABMT and radiotherapy in supratentorial high-grade astrocytomas: A report of 98 patients, in Dicke KA, Armitage JO, Dicke-Evinger (eds): Autologous Bone Marrow Transplantation: Proceedings of the Fifth International Symposium. Omaha, NE, The University of Nebraska Medical Center, 1991, pp 637-645
35. Mason WP, Grovas A, Halpern S, et al: Intensive chemotherapy and bone marrow rescue for young children with newly-diagnosed malignant brain tumors. J Clin Oncol 16:210-221, 1998