Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding

Biochemical and Biophysical Research Communications

Volumn 393, Issue 4, 2010, Pages 688-693

  Istrate, Monica A ^a   Nussler, Andreas K ^b   Eichelbaum, Michel ^a   Burk, Oliver ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

CYP3A4; Hepatocyte; Induction; Nuclear receptor; PXR

Indexed keywords

CELL NUCLEUS RECEPTOR; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; CYTOCHROME P450 3A4; PREGNANE X RECEPTOR; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA;

ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME INDUCTION; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN MOTIF;

BINDING, COMPETITIVE; CELL LINE, TUMOR; COUP TRANSCRIPTION FACTOR I; COUP TRANSCRIPTION FACTOR II; CYTOCHROME P-450 CYP3A; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; RECEPTORS, STEROID; RESPONSE ELEMENTS; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA;

EID: 77949492634     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.058     Document Type: Article

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