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Volumn 49, Issue , 2009, Pages 17-47

Many checkpoints on the road to cell death: Regulation of Fas-Fasl interactions and Fas signaling in peripheral immune responses

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; FAS LIGAND; FASLG PROTEIN, HUMAN; PROTEIN BCL 2;

EID: 77649330534     PISSN: 00801844     EISSN: 18610412     Source Type: Book Series    
DOI: 10.1007/400_2008_24     Document Type: Article
Times cited : (38)

References (183)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A (1996) Functional diversity of helper T lymphocytes. Nature 383:787-793
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 2
    • 0028856130 scopus 로고
    • Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver
    • Adachi M, Suematsu S, Kondo T, Ogasawara J, Tanaka T, Yoshida N, Nagata S (1995) Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver. Nat Genet 11:294-300
    • (1995) Nat Genet , vol.11 , pp. 294-300
    • Adachi, M.1    Suematsu, S.2    Kondo, T.3    Ogasawara, J.4    Tanaka, T.5    Yoshida, N.6    Nagata, S.7
  • 4
    • 0038198615 scopus 로고    scopus 로고
    • Actin dependent CD95 internalization is specific for Type i cells
    • Algeciras-Schimnich A, Peter ME (2003) Actin dependent CD95 internalization is specific for Type I cells. FEBS Lett 546:185-188
    • (2003) FEBS Lett , vol.546 , pp. 185-188
    • Algeciras-Schimnich, A.1    Peter, M.E.2
  • 6
    • 0028048353 scopus 로고
    • T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A
    • Anel A, Buferne M, Boyer C, Schmitt-Verhulst AM, Golstein P (1994) T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. Eur J Immunol 24:2469-2476
    • (1994) Eur J Immunol , vol.24 , pp. 2469-2476
    • Anel, A.1    Buferne, M.2    Boyer, C.3    Schmitt-Verhulst, A.M.4    Golstein, P.5
  • 7
    • 4143108125 scopus 로고    scopus 로고
    • CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells
    • Barnhart BC, Legembre P, Pietras E, Bubici C, Franzoso G, Peter ME (2004) CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO J 23:3175-3185
    • (2004) EMBO J , vol.23 , pp. 3175-3185
    • Barnhart, B.C.1    Legembre, P.2    Pietras, E.3    Bubici, C.4    Franzoso, G.5    Peter, M.E.6
  • 9
    • 0035037684 scopus 로고    scopus 로고
    • Membrane lipid microdomains and the role of PKCtheta in T cell activation
    • Bi K, Altman A (2001) Membrane lipid microdomains and the role of PKCtheta in T cell activation. Semin Immunol 13:139-146
    • (2001) Semin Immunol , vol.13 , pp. 139-146
    • Bi, K.1    Altman, A.2
  • 15
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F, Adams JM, Strasser A (1999) Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286:1735-1738
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5    Kontgen, F.6    Adams, J.M.7    Strasser, A.8
  • 16
    • 0036346708 scopus 로고    scopus 로고
    • ERM proteins and merlin: Integrators at the cell cortex
    • Bretscher A, Edwards K, and Fehon RG (2002) ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 3:586-599
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 586-599
    • Bretscher, A.1    Edwards, K.2    Fehon, R.G.3
  • 17
    • 0030018311 scopus 로고    scopus 로고
    • Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506
    • Brunner T, Yoo NJ, LaFace D, Ware CF, Green DR (1996) Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. Int Immunol 8:1017-1026
    • (1996) Int Immunol , vol.8 , pp. 1017-1026
    • Brunner, T.1    Yoo, N.J.2    Laface, D.3    Ware, C.F.4    Green, D.R.5
  • 21
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • Chan O, Shlomchik MJ (1998) A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J Immunol 160:51-59
    • (1998) J Immunol , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2
  • 22
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan FK, Chun HJ, Zheng L, Siegel RM, Bui KL, Lenardo MJ (2000) A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 288:2351-2354
    • (2000) Science , vol.288 , pp. 2351-2354
    • Chan, F.K.1    Chun, H.J.2    Zheng, L.3    Siegel, R.M.4    Bui, K.L.5    Lenardo, M.J.6
  • 23
    • 0035873417 scopus 로고    scopus 로고
    • CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: Evidence for involvement of CD44 in activation-induced cell death
    • Chen D, McKallip RJ, Zeytun A, Do Y, Lombard C, Robertson JL, Mak TW, Nagarkatti PS, Nagarkatti M (2001) CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death. J Immunol 166:5889-5897
    • (2001) J Immunol , vol.166 , pp. 5889-5897
    • Chen, D.1    McKallip, R.J.2    Zeytun, A.3    Do, Y.4    Lombard, C.5    Robertson, J.L.6    Mak, T.W.7    Nagarkatti, P.S.8    Nagarkatti, M.9
  • 25
    • 0034955304 scopus 로고    scopus 로고
    • Floating the raft hypothesis: Lipid rafts play a role in immune cell activation
    • Cherukuri A, Dykstra M, Pierce SK (2001) Floating the raft hypothesis: lipid rafts play a role in immune cell activation. Immunity 14:657-660
    • (2001) Immunity , vol.14 , pp. 657-660
    • Cherukuri, A.1    Dykstra, M.2    Pierce, S.K.3
  • 26
    • 0343618494 scopus 로고    scopus 로고
    • The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells
    • Chow WA, Fang JJ, Yee JK (2000) The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells. J Immunol 164:3512-3518
    • (2000) J Immunol , vol.164 , pp. 3512-3518
    • Chow, W.A.1    Fang, J.J.2    Yee, J.K.3
  • 27
    • 29144496895 scopus 로고    scopus 로고
    • Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis
    • Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, Lenardo MJ, Chan FK (2005) Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Nat Acad Sci U S A 102:18099-18104
    • (2005) Proc Nat Acad Sci U S A , vol.102 , pp. 18099-18104
    • Clancy, L.1    Mruk, K.2    Archer, K.3    Woelfel, M.4    Mongkolsapaya, J.5    Screaton, G.6    Lenardo, M.J.7    Chan, F.K.8
  • 28
    • 19244387337 scopus 로고    scopus 로고
    • Differential TCR signaling regulates apoptosis and immunopathology during antigen responses in vivo
    • Combadiere B, Reis e Sousa C, Trageser C, Zheng LX, Kim CR, Lenardo MJ (1998) Differential TCR signaling regulates apoptosis and immunopathology during antigen responses in vivo. Immunity 9:305-313
    • (1998) Immunity , vol.9 , pp. 305-313
    • Combadiere, B.1    Reis, E.2    Sousa, C.3    Trageser, C.4    Zheng, L.X.5    Kim, C.R.6    Lenardo, M.J.7
  • 29
    • 0037090252 scopus 로고    scopus 로고
    • Restricted localization of the TNF receptor CD120a to lipid rafts: A novel role for the death domain
    • Cottin V, Doan JE, Riches DW (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. J Immunol 168:4095-4102
    • (2002) J Immunol , vol.168 , pp. 4095-4102
    • Cottin, V.1    Doan, J.E.2    Riches, D.W.3
  • 32
    • 0036884315 scopus 로고    scopus 로고
    • T cell receptor ligation triggers novel nonapoptotic cell death pathways that are Fas-independent or Fas-dependent
    • Davidson WF, Haudenschild C, Kwon J, Williams MS (2002) T cell receptor ligation triggers novel nonapoptotic cell death pathways that are Fas-independent or Fas-dependent. J Immunol 169:6218-6230
    • (2002) J Immunol , vol.169 , pp. 6218-6230
    • Davidson, W.F.1    Haudenschild, C.2    Kwon, J.3    Williams, M.S.4
  • 33
    • 27144479900 scopus 로고    scopus 로고
    • Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors
    • Deng GM, Zheng L, Chan FK, Lenardo M (2005) Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors. Nat Med 11:1066-1072
    • (2005) Nat Med , vol.11 , pp. 1066-1072
    • Deng, G.M.1    Zheng, L.2    Chan, F.K.3    Lenardo, M.4
  • 35
    • 0034644505 scopus 로고    scopus 로고
    • Signaling takes shape in the immune system
    • Dustin ML, Chan AC (2000) Signaling takes shape in the immune system. Cell 103:283-294
    • (2000) Cell , vol.103 , pp. 283-294
    • Dustin, M.L.1    Chan, A.C.2
  • 37
    • 0035313050 scopus 로고    scopus 로고
    • Differential expression of Fas ligand in Th1 and Th2 cells is regulated by early growth response gene and NF-AT family members
    • Dzialo-Hatton R, Milbrandt J, Hockett RD, Jr., Weaver CT (2001) Differential expression of Fas ligand in Th1 and Th2 cells is regulated by early growth response gene and NF-AT family members. J Immunol 166:4534-4542
    • (2001) J Immunol , vol.166 , pp. 4534-4542
    • Dzialo-Hatton, R.1    Milbrandt, J.2    Hockett Jr., R.D.3    Weaver, C.T.4
  • 40
    • 33846247103 scopus 로고    scopus 로고
    • Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
    • Feig C, Tchikov V, Schutze S, Peter ME (2007) Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling. EMBO J 26:221-231
    • (2007) EMBO J , vol.26 , pp. 221-231
    • Feig, C.1    Tchikov, V.2    Schutze, S.3    Peter, M.E.4
  • 41
    • 0035881947 scopus 로고    scopus 로고
    • Fas/Fas ligand deficiency results in altered localization of anti-double-stranded DNA B cells and dendritic cells
    • Fields ML, Sokol CL, Eaton-Bassiri A, Seo S, Madaio MP, Erikson J (2001) Fas/Fas ligand deficiency results in altered localization of anti-double-stranded DNA B cells and dendritic cells. J Immunol 167:2370-2378
    • (2001) J Immunol , vol.167 , pp. 2370-2378
    • Fields, M.L.1    Sokol, C.L.2    Eaton-Bassiri, A.3    Seo, S.4    Madaio, M.P.5    Erikson, J.6
  • 44
    • 21244465055 scopus 로고    scopus 로고
    • In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death
    • Fritzsching B, Oberle N, Eberhardt N, Quick S, Haas J, Wildemann B, Krammer PH, Suri-Payer E (2005) In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. J Immunol 175:32-36
    • (2005) J Immunol , vol.175 , pp. 32-36
    • Fritzsching, B.1    Oberle, N.2    Eberhardt, N.3    Quick, S.4    Haas, J.5    Wildemann, B.6    Krammer, P.H.7    Suri-Payer, E.8
  • 47
    • 34249909831 scopus 로고    scopus 로고
    • Dominantnegative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID)
    • Garibyan L, Lobito AA, Siegel RM, Call ME, Wucherpfennig KW, Geha RS (2007) Dominantnegative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID) J Clin Invest 117:1550-1557
    • (2007) J Clin Invest , vol.117 , pp. 1550-1557
    • Garibyan, L.1    Lobito, A.A.2    Siegel, R.M.3    Call, M.E.4    Wucherpfennig, K.W.5    Geha, R.S.6
  • 48
    • 0033579820 scopus 로고    scopus 로고
    • Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc
    • Genestier L, Kasibhatla S, Brunner T, Green DR (1999) Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J Exp Med 189:231-239
    • (1999) J Exp Med , vol.189 , pp. 231-239
    • Genestier, L.1    Kasibhatla, S.2    Brunner, T.3    Green, D.R.4
  • 49
    • 33847311403 scopus 로고    scopus 로고
    • Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse
    • Gomez TS, Kumar K, Medeiros RB, Shimizu Y, Leibson PJ, Billadeau DD (2007) Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. Immunity 26:177-190
    • (2007) Immunity , vol.26 , pp. 177-190
    • Gomez, T.S.1    Kumar, K.2    Medeiros, R.B.3    Shimizu, Y.4    Leibson, P.J.5    Billadeau, D.D.6
  • 50
    • 0035284888 scopus 로고    scopus 로고
    • Cutting edge: The class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression
    • Gourley TS, Chang CH (2001) Cutting edge: the class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression. J Immunol 166:2917-2921
    • (2001) J Immunol , vol.166 , pp. 2917-2921
    • Gourley, T.S.1    Chang, C.H.2
  • 51
    • 34848903247 scopus 로고    scopus 로고
    • CTLs contain and use intracellular stores of FasL distinct from cytolytic granules
    • He JS, Ostergaard HL (2007) CTLs contain and use intracellular stores of FasL distinct from cytolytic granules. J Immunol 179:2339-2348
    • (2007) J Immunol , vol.179 , pp. 2339-2348
    • He, J.S.1    Ostergaard, H.L.2
  • 53
    • 0035575757 scopus 로고    scopus 로고
    • Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors
    • Hohlbaum AM, Gregory MS, Ju ST, Marshak-Rothstein A (2001) Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors. J Immunol 167:6217-6224
    • (2001) J Immunol , vol.167 , pp. 6217-6224
    • Hohlbaum, A.M.1    Gregory, M.S.2    Ju, S.T.3    Marshak-Rothstein, A.4
  • 54
    • 0031572509 scopus 로고    scopus 로고
    • Maintenance of clonotype specificity in CD95/Apo-1/ Fas-mediated apoptosis of mature T lymphocytes
    • Hornung F, Zheng L, Lenardo MJ (1997) Maintenance of clonotype specificity in CD95/Apo-1/ Fas-mediated apoptosis of mature T lymphocytes. J Immunol 159:3816-3822
    • (1997) J Immunol , vol.159 , pp. 3816-3822
    • Hornung, F.1    Zheng, L.2    Lenardo, M.J.3
  • 55
    • 3142682595 scopus 로고    scopus 로고
    • T cell receptor signaling: Beyond complex complexes
    • Huang Y, Wange RL (2004) T cell receptor signaling: beyond complex complexes. J Biol Chem 279:28827-28830
    • (2004) J Biol Chem , vol.279 , pp. 28827-28830
    • Huang, Y.1    Wange, R.L.2
  • 56
    • 0036195136 scopus 로고    scopus 로고
    • An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes
    • Hueber AO, Bernard AM, Herincs Z, Couzinet A, He HT (2002) An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes. EMBO Rep 3:190-196
    • (2002) EMBO Rep , vol.3 , pp. 190-196
    • Hueber, A.O.1    Bernard, A.M.2    Herincs, Z.3    Couzinet, A.4    He, H.T.5
  • 57
    • 38949119408 scopus 로고    scopus 로고
    • Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity
    • Hughes PD, Belz GT, Fortner KA, Budd RC, Strasser A, Bouillet P (2008) Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity 28:197-205
    • (2008) Immunity , vol.28 , pp. 197-205
    • Hughes, P.D.1    Belz, G.T.2    Fortner, K.A.3    Budd, R.C.4    Strasser, A.5    Bouillet, P.6
  • 59
    • 8744297444 scopus 로고    scopus 로고
    • Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha
    • Imamura R, Konaka K, Matsumoto N, Hasegawa M, Fukui M, Mukaida N, Kinoshita T, Suda T (2004) Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha. J Biol Chem 279:46415-46423
    • (2004) J Biol Chem , vol.279 , pp. 46415-46423
    • Imamura, R.1    Konaka, K.2    Matsumoto, N.3    Hasegawa, M.4    Fukui, M.5    Mukaida, N.6    Kinoshita, T.7    Suda, T.8
  • 60
    • 0030918820 scopus 로고    scopus 로고
    • In vivo detection of dendritic cell antigen presentation to CD4(+) T cells
    • Ingulli E, Mondino A, Khoruts A, Jenkins MK (1997) In vivo detection of dendritic cell antigen presentation to CD4(+) T cells. J Exp Med 185:2133-2141
    • (1997) J Exp Med , vol.185 , pp. 2133-2141
    • Ingulli, E.1    Mondino, A.2    Khoruts, A.3    Jenkins, M.K.4
  • 61
    • 0032727709 scopus 로고    scopus 로고
    • Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor
    • Janes PW, Ley SC, Magee AI (1999) Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J Cell Biol 147:447-461
    • (1999) J Cell Biol , vol.147 , pp. 447-461
    • Janes, P.W.1    Ley, S.C.2    Magee, A.I.3
  • 62
    • 0035880242 scopus 로고    scopus 로고
    • Major histocompatibility complex-mismatched allogeneic bone marrow transplantation using perforin and/or Fas ligand double-defective CD4(+) donor T cells: Involvement of cytotoxic function by donor lymphocytes prior to graft-versus-host disease pathogenesis
    • Jiang Z, Podack E, Levy RB (2001) Major histocompatibility complex-mismatched allogeneic bone marrow transplantation using perforin and/or Fas ligand double-defective CD4(+) donor T cells: involvement of cytotoxic function by donor lymphocytes prior to graft-versus-host disease pathogenesis. Blood 98:390-397
    • (2001) Blood , vol.98 , pp. 390-397
    • Jiang, Z.1    Podack, E.2    Levy, R.B.3
  • 64
    • 18344371455 scopus 로고    scopus 로고
    • Cutting edge: Fas Ligand (CD178) Cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity
    • Jodo S, Pidiyar VJ, Xiao S, Furusaki A, Sharma R (2005) Cutting edge: Fas Ligand (CD178) Cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity . J Immunol 174:4470-4474
    • (2005) J Immunol , vol.174 , pp. 4470-4474
    • Jodo, S.1    Pidiyar, V.J.2    Xiao, S.3    Furusaki, A.4    Sharma, R.5
  • 66
    • 33645295218 scopus 로고    scopus 로고
    • Lipid rafts in T cell receptor signalling
    • Kabouridis PS (2006) Lipid rafts in T cell receptor signalling. Mol Membr Biol 23:49-57
    • (2006) Mol Membr Biol , vol.23 , pp. 49-57
    • Kabouridis, P.S.1
  • 67
    • 0030842535 scopus 로고    scopus 로고
    • Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction
    • Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, Baekkeskov S (1997) Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat Med 3:738-743
    • (1997) Nat Med , vol.3 , pp. 738-743
    • Kang, S.M.1    Schneider, D.B.2    Lin, Z.3    Hanahan, D.4    Dichek, D.A.5    Stock, P.G.6    Baekkeskov, S.7
  • 68
    • 0033534465 scopus 로고    scopus 로고
    • Regulation of fas-ligand expression during activationinduced cell death in T lymphocytes via nuclear factor kappaB
    • Kasibhatla S, Genestier L, Green DR (1999) Regulation of fas-ligand expression during activationinduced cell death in T lymphocytes via nuclear factor kappaB. J Biol Chem 274:987-992
    • (1999) J Biol Chem , vol.274 , pp. 987-992
    • Kasibhatla, S.1    Genestier, L.2    Green, D.R.3
  • 69
    • 18744425429 scopus 로고    scopus 로고
    • The caspase-8 inhibitor FLIP promotes activation of NF-C:\Documents and Settings\KGunasekaran\Desktop\WOBLB and Erk signaling pathways
    • Kataoka T, Budd RC, Holler N, Thome M, Martinon F (2000) The caspase-8 inhibitor FLIP promotes activation of NF-C:\Documents and Settings\KGunasekaran\ Desktop\WOBLB and Erk signaling pathways. Curr Biol 10:640-648
    • (2000) Curr Biol , vol.10 , pp. 640-648
    • Kataoka, T.1    Budd, R.C.2    Holler, N.3    Thome, M.4    Martinon, F.5
  • 70
    • 0035895967 scopus 로고    scopus 로고
    • Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement
    • Kavurma MM, Santiago FS, Bonfoco E, Khachigian LM (2001) Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement. J Biol Chem 276:4964-4971
    • (2001) J Biol Chem , vol.276 , pp. 4964-4971
    • Kavurma, M.M.1    Santiago, F.S.2    Bonfoco, E.3    Khachigian, L.M.4
  • 71
    • 0037183972 scopus 로고    scopus 로고
    • Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1
    • Kavurma MM, Bobryshev Y, Khachigian LM (2002) Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1. J Biol Chem 277:36244-36252
    • (2002) J Biol Chem , vol.277 , pp. 36244-36252
    • Kavurma, M.M.1    Bobryshev, Y.2    Khachigian, L.M.3
  • 72
    • 0033386808 scopus 로고    scopus 로고
    • Caspase activation is required for T cell proliferation
    • Kennedy NJ, Kataoka T, Tschopp J, Budd RC (1999) Caspase activation is required for T cell proliferation. J Exp Med 190:1891-1896
    • (1999) J Exp Med , vol.190 , pp. 1891-1896
    • Kennedy, N.J.1    Kataoka, T.2    Tschopp, J.3    Budd, R.C.4
  • 74
    • 0036467365 scopus 로고    scopus 로고
    • Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter
    • Kirchhoff S, Sebens T, Baumann S, Krueger A, Zawatzky R, Li-Weber M, Meinl E, Neipel F, Fleckenstein B, Krammer PH (2002) Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter. J Immunol 168:1226-1234
    • (2002) J Immunol , vol.168 , pp. 1226-1234
    • Kirchhoff, S.1    Sebens, T.2    Baumann, S.3    Krueger, A.4    Zawatzky, R.5    Li-Weber, M.6    Meinl, E.7    Neipel, F.8    Fleckenstein, B.9    Krammer, P.H.10
  • 76
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 14:5579-5588
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Krammer, P.H.6    Peter, M.E.7
  • 77
    • 0027183703 scopus 로고
    • Activation interferes with the APO-1 pathway in mature human T cells
    • Klas C, Debatin KM, Jonker RR, Krammer PH (1993) Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 5:625-630
    • (1993) Int Immunol , vol.5 , pp. 625-630
    • Klas, C.1    Debatin, K.M.2    Jonker, R.R.3    Krammer, P.H.4
  • 78
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S (1997) Essential roles of the Fas ligand in the development of hepatitis. Nat Med 3:409-413
    • (1997) Nat Med , vol.3 , pp. 409-413
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 79
    • 0030560974 scopus 로고    scopus 로고
    • Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: Role of decreased intracellular TNF-alpha
    • Kovacs B, Vassilopoulos D, Vogelgesang SA, Tsokos GC (1996) Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: role of decreased intracellular TNF-alpha. Clin Immunol Immunopathol 81:293-302
    • (1996) Clin Immunol Immunopathol , vol.81 , pp. 293-302
    • Kovacs, B.1    Vassilopoulos, D.2    Vogelgesang, S.A.3    Tsokos, G.C.4
  • 81
    • 0031465970 scopus 로고    scopus 로고
    • Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
    • Latinis KM, Norian LA, Eliason SL, Koretzky GA (1997b) Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells. J Biol Chem 272:31427-31434
    • (1997) J Biol Chem , vol.272 , pp. 31427-31434
    • Latinis, K.M.1    Norian, L.A.2    Eliason, S.L.3    Koretzky, G.A.4
  • 82
    • 0030017476 scopus 로고    scopus 로고
    • Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice
    • Lau HT, Yu M, Fontana A, Stoeckert CJ, Jr. (1996) Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science 273:109-112
    • (1996) Science , vol.273 , pp. 109-112
    • Lau, H.T.1    Yu, M.2    Fontana, A.3    Stoeckert Jr., C.J.4
  • 83
    • 34548125310 scopus 로고    scopus 로고
    • T(H)-17 differentiation: Of mice and men
    • Laurence A, O'Shea JJ (2007) T(H)-17 differentiation: of mice and men. Nat Immunol 8:903-905
    • (2007) Nat Immunol , vol.8 , pp. 903-905
    • Laurence, A.1    O'Shea, J.J.2
  • 84
    • 40449130509 scopus 로고    scopus 로고
    • Interleukin-22: A sheep in wolf's clothing
    • Laurence A, O'Shea JJ, Watford WT (2008) Interleukin-22: a sheep in wolf's clothing. Nat Med 14:247-249
    • (2008) Nat Med , vol.14 , pp. 247-249
    • Laurence, A.1    O'Shea, J.J.2    Watford, W.T.3
  • 86
    • 0036181491 scopus 로고    scopus 로고
    • Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells
    • Lee MO, Kang HJ, Kim YM, Oum JH, Park J (2002) Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells. Eur J Biochem 269:1162-1170
    • (2002) Eur J Biochem , vol.269 , pp. 1162-1170
    • Lee, M.O.1    Kang, H.J.2    Kim, Y.M.3    Oum, J.H.4    Park, J.5
  • 88
    • 28844456504 scopus 로고    scopus 로고
    • Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression
    • Legge KL, Braciale TJ (2005) Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression. Immunity 23:649-659
    • (2005) Immunity , vol.23 , pp. 649-659
    • Legge, K.L.1    Braciale, T.J.2
  • 89
    • 0035405808 scopus 로고    scopus 로고
    • Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts
    • Legler DF, Doucey MA, Cerottini JC, Bron C, Luescher IF (2001) Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts. FASEB J 15:1601-1603
    • (2001) FASEB J , vol.15 , pp. 1601-1603
    • Legler, D.F.1    Doucey, M.A.2    Cerottini, J.C.3    Bron, C.4    Luescher, I.F.5
  • 90
    • 0038742813 scopus 로고    scopus 로고
    • Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation
    • Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C (2003) Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity 18:655-664
    • (2003) Immunity , vol.18 , pp. 655-664
    • Legler, D.F.1    Micheau, O.2    Doucey, M.A.3    Tschopp, J.4    Bron, C.5
  • 91
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo M, Chan KM, Hornung F, McFarland H, Siegel R, Wang J, Zheng L (1999) Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 17:221-253
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, K.M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 92
    • 12144251368 scopus 로고    scopus 로고
    • Activation-dependent FasL expression in T lymphocytes and Natural Killer cells
    • Lettau M, Qian J, Kabelitz D, Janssen O (2004) Activation-dependent FasL expression in T lymphocytes and Natural Killer cells. Signal Transduction 4:206-211
    • (2004) Signal Transduction , vol.4 , pp. 206-211
    • Lettau, M.1    Qian, J.2    Kabelitz, D.3    Janssen, O.4
  • 93
  • 94
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94:491-501
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 95
    • 0025685264 scopus 로고
    • Interferon gamma plays a critical role in induced cell death of effector T cell: A possible third mechanism of self-tolerance
    • Liu Y, Janeway CA, Jr. (1990) Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance. J Exp Med 172:1735-1739
    • (1990) J Exp Med , vol.172 , pp. 1735-1739
    • Liu, Y.1    Janeway Jr., C.A.2
  • 96
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 97
    • 5044228305 scopus 로고    scopus 로고
    • Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation
    • Ma Y, Liu H, Tu-Rapp H, Thiesen HJ, Ibrahim SM, Cole SM, Pope RM (2004) Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation. Nat Immunol 5:380-387
    • (2004) Nat Immunol , vol.5 , pp. 380-387
    • Ma, Y.1    Liu, H.2    Tu-Rapp, H.3    Thiesen, H.J.4    Ibrahim, S.M.5    Cole, S.M.6    Pope, R.M.7
  • 98
    • 0032548842 scopus 로고    scopus 로고
    • Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal
    • Martin DA, Siegel RM, Zheng L, Lenardo MJ (1998) Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J Biol Chem 273:4345-4349
    • (1998) J Biol Chem , vol.273 , pp. 4345-4349
    • Martin, D.A.1    Siegel, R.M.2    Zheng, L.3    Lenardo, M.J.4
  • 100
    • 0034654543 scopus 로고    scopus 로고
    • Role of activator protein-1 in TCR-mediated regulation of the murine fasl promoter
    • Matsui K, Xiao S, Fine A, Ju ST (2000) Role of activator protein-1 in TCR-mediated regulation of the murine fasl promoter. J Immunol 164:3002-3008
    • (2000) J Immunol , vol.164 , pp. 3002-3008
    • Matsui, K.1    Xiao, S.2    Fine, A.3    Ju, S.T.4
  • 101
    • 0033583315 scopus 로고    scopus 로고
    • Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1
    • McClure RF, Heppelmann CJ, Paya CV (1999) Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1. J Biol Chem 274:7756-7762
    • (1999) J Biol Chem , vol.274 , pp. 7756-7762
    • McClure, R.F.1    Heppelmann, C.J.2    Paya, C.V.3
  • 103
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 104
    • 0033613847 scopus 로고    scopus 로고
    • Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells
    • Mittelstadt PR, Ashwell JD (1999) Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells. J Biol Chem 274:3222-3227
    • (1999) J Biol Chem , vol.274 , pp. 3222-3227
    • Mittelstadt, P.R.1    Ashwell, J.D.2
  • 105
    • 0031730436 scopus 로고    scopus 로고
    • Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand
    • Miwa K, Asano M, Horai R, Iwakura Y, Nagata S, Suda T (1998) Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand. Nat Med 4:1287-1292
    • (1998) Nat Med , vol.4 , pp. 1287-1292
    • Miwa, K.1    Asano, M.2    Horai, R.3    Iwakura, Y.4    Nagata, S.5    Suda, T.6
  • 106
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yonehara S, Taniguchi N (1992) Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 149:3753-3758
    • (1992) J Immunol , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3    Tsuji, T.4    Yachie, A.5    Yonehara, S.6    Taniguchi, N.7
  • 107
    • 11144275900 scopus 로고    scopus 로고
    • Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages
    • Monari C, Bistoni F, Casadevall A, Pericolini E, Pietrella D, Kozel TR, Vecchiarelli A (2005) Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages. J Infect Dis 191:127-137
    • (2005) J Infect Dis , vol.191 , pp. 127-137
    • Monari, C.1    Bistoni, F.2    Casadevall, A.3    Pericolini, E.4    Pietrella, D.5    Kozel, T.R.6    Vecchiarelli, A.7
  • 109
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: Elusive or illusive?
    • Munro S (2003) Lipid rafts: elusive or illusive? Cell 115:377-388
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 110
    • 1142287412 scopus 로고    scopus 로고
    • Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
    • Muppidi JR, Siegel RM (2004) Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat Immunol 5:182-189
    • (2004) Nat Immunol , vol.5 , pp. 182-189
    • Muppidi, J.R.1    Siegel, R.M.2
  • 111
    • 5644222552 scopus 로고    scopus 로고
    • Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
    • Muppidi JR, Tschopp J, Siegel RM (2004) Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 21:461-465
    • (2004) Immunity , vol.21 , pp. 461-465
    • Muppidi, J.R.1    Tschopp, J.2    Siegel, R.M.3
  • 112
    • 33744517489 scopus 로고    scopus 로고
    • Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
    • Muppidi JR, Lobito AA, Ramaswamy M, Yang JK, Wang L, Wu H, Siegel RM (2006) Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis. Cell Death Differ 13:1641-1650
    • (2006) Cell Death Differ , vol.13 , pp. 1641-1650
    • Muppidi, J.R.1    Lobito, A.A.2    Ramaswamy, M.3    Yang, J.K.4    Wang, L.5    Wu, H.6    Siegel, R.M.7
  • 114
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
    • Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, et al (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J Biol Chem 267:10709-10715
    • (1992) J Biol Chem , vol.267 , pp. 10709-10715
    • Oehm, A.1    Behrmann, I.2    Falk, W.3    Pawlita, M.4    Maier, G.5    Klas, C.6    Li-Weber, M.7    Richards, S.8    Dhein, J.9    Trauth, B.C.10
  • 116
    • 0030684009 scopus 로고    scopus 로고
    • Requirement of cysteine-rich repeats of the Fas receptor for binding by the Fas ligand
    • Orlinick JR, Vaishnaw A, Elkon KB, Chao MV (1997) Requirement of cysteine-rich repeats of the Fas receptor for binding by the Fas ligand. J Biol Chem 272:28889-28894
    • (1997) J Biol Chem , vol.272 , pp. 28889-28894
    • Orlinick, J.R.1    Vaishnaw, A.2    Elkon, K.B.3    Chao, M.V.4
  • 117
    • 0033559492 scopus 로고    scopus 로고
    • Soluble Fas ligand is chemotactic for human neutrophilic polymorphonuclear leukocytes
    • Ottonello L, Tortolina G, Amelotti M, Dallegri F (1999) Soluble Fas ligand is chemotactic for human neutrophilic polymorphonuclear leukocytes. J Immunol 162:3601-3606
    • (1999) J Immunol , vol.162 , pp. 3601-3606
    • Ottonello, L.1    Tortolina, G.2    Amelotti, M.3    Dallegri, F.4
  • 118
    • 27544432516 scopus 로고    scopus 로고
    • Nonapoptotic functions of FADD-binding death receptors and their signaling molecules
    • Park SM, Schickel R, Peter ME (2005) Nonapoptotic functions of FADD-binding death receptors and their signaling molecules. Curr Opin Cell Biol 17:610-616
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 610-616
    • Park, S.M.1    Schickel, R.2    Peter, M.E.3
  • 119
    • 0034597013 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: A novel regulatory mechanism of the CD95 apoptotic pathway
    • Parlato S, Giammarioli AM, Logozzi M, Lozupone F, Matarrese P, Luciani F, Falchi M, Malorni W, Fais S (2000) CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway. EMBO J 19: 5123-5134
    • (2000) EMBO J , vol.19 , pp. 5123-5134
    • Parlato, S.1    Giammarioli, A.M.2    Logozzi, M.3    Lozupone, F.4    Matarrese, P.5    Luciani, F.6    Falchi, M.7    Malorni, W.8    Fais, S.9
  • 120
    • 41949099869 scopus 로고    scopus 로고
    • Dissecting lipid raft facilitated cell signaling pathways in cancer
    • Patra SK (2008) Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim Biophys Acta 1785:182-206
    • (2008) Biochim Biophys Acta , vol.1785 , pp. 182-206
    • Patra, S.K.1
  • 121
    • 0030949563 scopus 로고    scopus 로고
    • Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex
    • Peter ME, Kischkel FC, Scheuerpflug CG, Medema JP, Debatin KM, Krammer PH (1997) Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex. Eur J Immunol 27:1207-1212
    • (1997) Eur J Immunol , vol.27 , pp. 1207-1212
    • Peter, M.E.1    Kischkel, F.C.2    Scheuerpflug, C.G.3    Medema, J.P.4    Debatin, K.M.5    Krammer, P.H.6
  • 123
    • 0028172588 scopus 로고
    • Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death
    • Ramsdell F, Seaman MS, Miller RE, Picha KS, Kennedy MK, Lynch DH (1994a) Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. Int Immunol 6:1545-1553
    • (1994) Int Immunol , vol.6 , pp. 1545-1553
    • Ramsdell, F.1    Seaman, M.S.2    Miller, R.E.3    Picha, K.S.4    Kennedy, M.K.5    Lynch, D.H.6
  • 126
    • 0037037582 scopus 로고    scopus 로고
    • Interferon gamma is required for activationinduced death of T lymphocytes
    • Refaeli Y, Van Parijs L, Alexander SI, Abbas AK (2002) Interferon gamma is required for activationinduced death of T lymphocytes. J Exp Med 196:999-1005
    • (2002) J Exp Med , vol.196 , pp. 999-1005
    • Refaeli, Y.1    Van Parijs, L.2    Alexander, S.I.3    Abbas, A.K.4
  • 128
    • 34247590130 scopus 로고    scopus 로고
    • Palmitoylation of ligands, receptors, and intracellular signaling molecules
    • Resh MD (2006) Palmitoylation of ligands, receptors, and intracellular signaling molecules. Sci STKE 2006:re14
    • (2006) Sci STKE
    • Resh, M.D.1
  • 129
    • 34247345833 scopus 로고    scopus 로고
    • The apoptosome: Signalling platform of cell death
    • Riedl S, Salvesen G (2007) The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 8:405-413
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 405-413
    • Riedl, S.1    Salvesen, G.2
  • 139
    • 33645299092 scopus 로고    scopus 로고
    • Caspases at the crossroads of immune-cell life and death
    • Siegel RM (2006) Caspases at the crossroads of immune-cell life and death. Nat Rev Immunol 6:308-317
    • (2006) Nat Rev Immunol , vol.6 , pp. 308-317
    • Siegel, R.M.1
  • 141
    • 9444268061 scopus 로고    scopus 로고
    • SPOTS: Signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane
    • Siegel RM, Muppidi JR, Sarker M, Lobito A, Jen M, Martin D, Straus SE, Lenardo MJ (2004) SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. J Cell Biol 167:735-744
    • (2004) J Cell Biol , vol.167 , pp. 735-744
    • Siegel, R.M.1    Muppidi, J.R.2    Sarker, M.3    Lobito, A.4    Jen, M.5    Martin, D.6    Straus, S.E.7    Lenardo, M.J.8
  • 142
  • 143
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D (2000) Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1:31-39
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 144
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer GG, Abbas AK (1994) The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365-371
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 146
    • 0036514975 scopus 로고    scopus 로고
    • Autoimmune thyroid disease: New models of cell death in autoimmunity
    • Stassi G, De Maria R (2002) Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2:195-204
    • (2002) Nat Rev Immunol , vol.2 , pp. 195-204
    • Stassi, G.1    De Maria, R.2
  • 147
    • 33749185296 scopus 로고    scopus 로고
    • Centrosome polarization delivers secretory granules to the immunological synapse
    • Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM (2006) Centrosome polarization delivers secretory granules to the immunological synapse. Nature 443:462-465
    • (2006) Nature , vol.443 , pp. 462-465
    • Stinchcombe, J.C.1    Majorovits, E.2    Bossi, G.3    Fuller, S.4    Griffiths, G.M.5
  • 149
    • 0345059209 scopus 로고    scopus 로고
    • An inherited disorder of lymphocyte apoptosis: The autoimmune lymphoproliferative syndrome
    • Straus SE, Sneller M, Lenardo MJ, Puck JM, Strober W (1999) An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome. Ann Intern Med 130:591-601
    • (1999) Ann Intern Med , vol.130 , pp. 591-601
    • Straus, S.E.1    Sneller, M.2    Lenardo, M.J.3    Puck, J.M.4    Strober, W.5
  • 152
    • 0031452949 scopus 로고    scopus 로고
    • Membrane fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing
    • Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S (1997) Membrane fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 186:2045-2050
    • (1997) J Exp Med , vol.186 , pp. 2045-2050
    • Suda, T.1    Hashimoto, H.2    Tanaka, M.3    Ochi, T.4    Nagata, S.5
  • 153
    • 38449113090 scopus 로고    scopus 로고
    • Cutting edge: Two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation
    • Sun M, Lee S, Karray S, Levi-Strauss M, Ames KT, Fink PJ (2007) Cutting edge: two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation. J Immunol 179:5639-5643
    • (2007) J Immunol , vol.179 , pp. 5639-5643
    • Sun, M.1    Lee, S.2    Karray, S.3    Levi-Strauss, M.4    Ames, K.T.5    Fink, P.J.6
  • 154
    • 0029920922 scopus 로고    scopus 로고
    • A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand- induced apoptosis
    • Suss G, Shortman K (1996) A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand- induced apoptosis. J Exp Med 183:1789-1796
    • (1996) J Exp Med , vol.183 , pp. 1789-1796
    • Suss, G.1    Shortman, K.2
  • 156
    • 0037124366 scopus 로고    scopus 로고
    • Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells
    • Tan JT, Ernst B, Kieper WC, LeRoy E, Sprent J, Surh CD (2002) Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med 195:1523-1532
    • (2002) J Exp Med , vol.195 , pp. 1523-1532
    • Tan, J.T.1    Ernst, B.2    Kieper, W.C.3    Leroy, E.4    Sprent, J.5    Surh, C.D.6
  • 157
    • 33645879828 scopus 로고    scopus 로고
    • Helper T cell differentiation enters a new era: Le roi est mort; Vive le roi!
    • Tato CM, Laurence A, O'Shea JJ (2006) Helper T cell differentiation enters a new era: le roi est mort; vive le roi! J Exp Med 203:809-812
    • (2006) J Exp Med , vol.203 , pp. 809-812
    • Tato, C.M.1    Laurence, A.2    O'Shea, J.J.3
  • 159
    • 18844449626 scopus 로고    scopus 로고
    • Vav-family proteins in T-cell signalling
    • Tybulewicz VL (2005) Vav-family proteins in T-cell signalling. Curr Opin Immunol 17:267-274
    • (2005) Curr Opin Immunol , vol.17 , pp. 267-274
    • Tybulewicz, V.L.1
  • 161
    • 0032931219 scopus 로고    scopus 로고
    • The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations
    • [published erratum appears in J Clin Invest 1999 Apr;103(7):1099]
    • Vaishnaw AK, Orlinick JR, Chu JL, Krammer PH, Chao MV, Elkon KB (1999) The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations [published erratum appears in J Clin Invest 1999 Apr;103(7):1099]. J Clin Invest 103:355-363
    • (1999) J Clin Invest , vol.103 , pp. 355-363
    • Vaishnaw, A.K.1    Orlinick, J.R.2    Chu, J.L.3    Krammer, P.H.4    Chao, M.V.5    Elkon, K.B.6
  • 162
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
    • Van Parijs L, Peterson DA, Abbas AK (1998) The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 8:265-274
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 163
    • 0036204018 scopus 로고    scopus 로고
    • Cell death regulation by the mammalian IAP antagonist Diablo/ Smac
    • Verhagen AM, Vaux DL (2002) Cell death regulation by the mammalian IAP antagonist Diablo/ Smac. Apoptosis 7:163-166
    • (2002) Apoptosis , vol.7 , pp. 163-166
    • Verhagen, A.M.1    Vaux, D.L.2
  • 164
    • 0035851918 scopus 로고    scopus 로고
    • Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
    • Villalba M, Bi K, Rodriguez F, Tanaka Y, Schoenberger S, Altman A (2001) Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells. J Cell Biol 155:331-338
    • (2001) J Cell Biol , vol.155 , pp. 331-338
    • Villalba, M.1    Bi, K.2    Rodriguez, F.3    Tanaka, Y.4    Schoenberger, S.5    Altman, A.6
  • 165
    • 0033248120 scopus 로고    scopus 로고
    • Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death
    • Villalba M, Kasibhatla S, Genestier L, Mahboubi A, Green DR, Altman A (1999) Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death. J Immunol 163:5813-5819
    • (1999) J Immunol , vol.163 , pp. 5813-5819
    • Villalba, M.1    Kasibhatla, S.2    Genestier, L.3    Mahboubi, A.4    Green, D.R.5    Altman, A.6
  • 168
    • 0033613826 scopus 로고    scopus 로고
    • T lymphocyte costimulation mediated by reorganization of membrane microdomains
    • Viola A, Schroeder S, Sakakibara Y, Lanzavecchia A (1999) T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 283:680-682
    • (1999) Science , vol.283 , pp. 680-682
    • Viola, A.1    Schroeder, S.2    Sakakibara, Y.3    Lanzavecchia, A.4
  • 170
    • 0032563871 scopus 로고    scopus 로고
    • Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression
    • Wang R, Brunner T, Zhang L, Shi Y (1998) Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression. Oncogene 17:1503-1508
    • (1998) Oncogene , vol.17 , pp. 1503-1508
    • Wang, R.1    Brunner, T.2    Zhang, L.3    Shi, Y.4
  • 171
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S (1992a) Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 173
    • 38949210228 scopus 로고    scopus 로고
    • Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction
    • Weant AE, Michalek RD, Khan IU, Holbrook BC, Willingham MC, Grayson JM (2008) Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction. Immunity 28:218-230
    • (2008) Immunity , vol.28 , pp. 218-230
    • Weant, A.E.1    Michalek, R.D.2    Khan, I.U.3    Holbrook, B.C.4    Willingham, M.C.5    Grayson, J.M.6
  • 174
    • 0030782720 scopus 로고    scopus 로고
    • T cell receptor signals enhance susceptibility to Fas-mediated apoptosis
    • Wong B, Arron J, Choi Y (1997) T cell receptor signals enhance susceptibility to Fas-mediated apoptosis. J Exp Med 186:1939-1944
    • (1997) J Exp Med , vol.186 , pp. 1939-1944
    • Wong, B.1    Arron, J.2    Choi, Y.3
  • 175
    • 0038446861 scopus 로고    scopus 로고
    • Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: Implications for agonistic antibody-based therapeutics
    • Xu Y, Szalai AJ, Zhou T, Zinn KR, Chaudhuri TR, Li X, Koopman WJ, Kimberly RP (2003) Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics. J Immunol 171:562-568
    • (2003) J Immunol , vol.171 , pp. 562-568
    • Xu, Y.1    Szalai, A.J.2    Zhou, T.3    Zinn, K.R.4    Chaudhuri, T.R.5    Li, X.6    Koopman, W.J.7    Kimberly, R.P.8
  • 177
    • 0024596722 scopus 로고
    • A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor
    • Yonehara S, Ishii A, Yonehara M (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756
    • (1989) J Exp Med , vol.169 , pp. 1747-1756
    • Yonehara, S.1    Ishii, A.2    Yonehara, M.3
  • 178
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9:47-59
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 179
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activationinduced T-cell proliferation are defective in mice lacking FADD/Mort1
    • Zhang J, Cado D, Chen A, Kabra NH, Winoto A (1998) Fas-mediated apoptosis and activationinduced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392:296-300
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 180
    • 33645973995 scopus 로고    scopus 로고
    • Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules
    • Zhang M, Park SM, Wang Y, Shah R, Liu N, Murmann AE, Wang CR, Peter ME, Ashton-Rickardt PG (2006) Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules. Immunity 24:451-461
    • (2006) Immunity , vol.24 , pp. 451-461
    • Zhang, M.1    Park, S.M.2    Wang, Y.3    Shah, R.4    Liu, N.5    Murmann, A.E.6    Wang, C.R.7    Peter, M.E.8    Ashton-Rickardt, P.G.9
  • 181
    • 23844548539 scopus 로고    scopus 로고
    • Conditional Fas-Associated Death Domain Protein (FADD):GFP Knockout Mice Reveal FADD Is Dispensable in Thymic Development but Essential in Peripheral T Cell Homeostasis
    • Zhang Y, Rosenberg S, Wang H, Imtiyaz HZ, Hou YJ, Zhang J (2005) Conditional Fas-Associated Death Domain Protein (FADD):GFP Knockout Mice Reveal FADD Is Dispensable in Thymic Development but Essential in Peripheral T Cell Homeostasis. J Immunol 175:3033-3044
    • (2005) J Immunol , vol.175 , pp. 3033-3044
    • Zhang, Y.1    Rosenberg, S.2    Wang, H.3    Imtiyaz, H.Z.4    Hou, Y.J.5    Zhang, J.6
  • 183
    • 33846821720 scopus 로고    scopus 로고
    • Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation
    • Zuccato E, Blott E, Holt O, Sigismund S, Shaw M, Bossi G, Griffiths G (2007) Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation. J Cell Sci 120:191-199
    • (2007) J Cell Sci , vol.120 , pp. 191-199
    • Zuccato, E.1    Blott, E.2    Holt, O.3    Sigismund, S.4    Shaw, M.5    Bossi, G.6    Griffiths, G.7


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