Cutting edge: The class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression

Journal of Immunology

Volumn 166, Issue 5, 2001, Pages 2917-2921

  Gourley, T S ^a   Chang, C H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL DEATH; CELL SURFACE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE; TARGET CELL;

EID: 0035284888     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.5.2917     Document Type: Article

References (30)

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3. Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells
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5. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
6. Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand
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8. Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
9. Inhibitory funcfion of two NFAT family members in lymphoid homeostasis and Th2 development
10. Sequential involvement of NFAT and Egr transcription factors in FasL regulation
11. Cyclosporin A-sensitive transcription factor Egr-3 regulated Fas ligand expression
12. Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1
13. Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor κB
14. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
15. Class II transactivator regulates the expression of multiple genes involved in antigen presentation
16. Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter
17. MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300
18. Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes
19. Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator
20. The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32
21. A novel role for the major histocompatibility complex class II transactivator CIITA in the repression of IL-4 production
22. 2+/calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene
23. CIITA activates the expression of MHC class II genes in mouse T cells
24. Autocrine growth inhibition of a cloned line of helper T cells
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26. Activation-induced cell death in T cell hybridomas is due to apoptosis: Morphologic aspects and DNA fragmentation
27. Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter
28. A possible involvement of Fas-Fas ligand signaling in the pathogenesis of murine autoimmune gastritis
29. The tumor counterattack hypothesis revisited: Colon cancer cells do not induce T cell apoptosis via the Fas (CD95, APO-I) pathway
30. cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)