-
2
-
-
0034962051
-
Mechanisms of ageing
-
Bürkle A. Mechanisms of ageing. Eye 2001; 15: 371-375.
-
(2001)
Eye
, vol.15
, pp. 371-375
-
-
Bürkle, A.1
-
3
-
-
0034992999
-
Stress, DNA damage and ageing-an integrative approach
-
Von Zglinicki T, Bürkle A and Kirkwood TB. Stress, DNA damage and ageing-an integrative approach. Exp Gerontol 2001; 36: 1049-1062.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1049-1062
-
-
von Zglinicki, T.1
Bürkle, A.2
Kirkwood, T.B.3
-
4
-
-
0036236006
-
The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
-
Brunk UT and Terman A. The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 2002; 269: 1996-2002.
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
6
-
-
77049308856
-
A theory based on free radical and radiation chemistry
-
Harman D. A theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298-300.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
7
-
-
0015319592
-
The biological clock: The mitochondria
-
Harman D. The biological clock: the mitochondria. J Am Geriatr Soc 1972; 20: 145-147.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
8
-
-
0020516814
-
Free radical theory of aging: Consequences of mitochondrial aging
-
Harman D. Free radical theory of aging: Consequences of mitochondrial aging. Age 1983; 6: 86-94.
-
(1983)
Age
, vol.6
, pp. 86-94
-
-
Harman, D.1
-
9
-
-
0035685590
-
Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging
-
Lee CH and Wei YH. Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging. Biogerentology 2001; 2: 231-244.
-
(2001)
Biogerentology
, vol.2
, pp. 231-244
-
-
Lee, C.H.1
Wei, Y.H.2
-
10
-
-
10344227782
-
Aging, oxidative stress, and mitochondrial uncoupling
-
Harper ME, Bevilacqua L, Hagopian K, Weindruch R and Ramsey JJ. Aging, oxidative stress, and mitochondrial uncoupling. Acta Physiol Scand 2004; 182: 321-331.
-
(2004)
Acta Physiol Scand
, vol.182
, pp. 321-331
-
-
Harper, M.E.1
Bevilacqua, L.2
Hagopian, K.3
Weindruch, R.4
Ramsey, J.J.5
-
11
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S and Finkel T. Mitochondria, oxidants, and aging. Cell 2005; 120: 483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
14
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
-
Sohal RS, Ku HH, Agarwal S, Forster MJ and Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 1994; 74: 121-133.
-
(1994)
Mech Ageing Dev
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
15
-
-
0029594475
-
Differential oxidative damage to mitochondrial proteins during aging
-
Agarwal S and Sohal RS. Differential oxidative damage to mitochondrial proteins during aging. Mech Ageing Dev 1995; 85: 55-63.
-
(1995)
Mech Ageing Dev
, vol.85
, pp. 55-63
-
-
Agarwal, S.1
Sohal, R.S.2
-
16
-
-
0029998087
-
Aging of the liver: Age-associated mitochondrial damage in intact hepatocytes
-
Sastre J, Pallardó FV, Plá R, Pellín A, Juan G, O'Connor JE, et al. Aging of the liver: age-associated mitochondrial damage in intact hepatocytes. Hepatology 1996; 24: 1199-1205.
-
(1996)
Hepatology
, vol.24
, pp. 1199-1205
-
-
Sastre, J.1
Pallardó, F.V.2
Plá, R.3
Pellín, A.4
Juan, G.5
O'Connor, J.E.6
-
17
-
-
0027534583
-
Modulation of membrane phospholipid fatty acid composition by age and food restriction
-
Laganiere S and Yu BP. Modulation of membrane phospholipid fatty acid composition by age and food restriction. Gerontology 1993; 39: 7-18.
-
(1993)
Gerontology
, vol.39
, pp. 7-18
-
-
Laganiere, S.1
Yu, B.P.2
-
18
-
-
0026603840
-
Cardiolipins and biomembrane function
-
Hoch FL. Cardiolipins and biomembrane function. Biochim Biophys Acta 1992; 1113: 71-133.
-
(1992)
Biochim Biophys Acta
, vol.1113
, pp. 71-133
-
-
Hoch, F.L.1
-
19
-
-
0032513135
-
Peroxidative damage to cardiac mitochondria: Cytochrome oxidase and cardiolipin alterations
-
Paradies G, Ruggiero FM, Petrosillo G and Quagliariello E. Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations. FEBS Lett 1998; 424: 155-158.
-
(1998)
FEBS Lett
, vol.424
, pp. 155-158
-
-
Paradies, G.1
Ruggiero, F.M.2
Petrosillo, G.3
Quagliariello, E.4
-
20
-
-
0032573066
-
Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
-
Yan LJ and Sohal RS. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc Natl Acad Sci USA 1998; 95: 12896-12901.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12896-12901
-
-
Yan, L.J.1
Sohal, R.S.2
-
21
-
-
0026357256
-
The inactivation of mitochondrial F1 ATPase by H2O2 is mediated by iron ions not tightly bound in the protein
-
Lippe G, Comelli M, Mazzilis D, Sala FD and Mavelli I. The inactivation of mitochondrial F1 ATPase by H2O2 is mediated by iron ions not tightly bound in the protein. Biochem Biophys Res Commun 1991; 181: 764-770.
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 764-770
-
-
Lippe, G.1
Comelli, M.2
Mazzilis, D.3
Sala, F.D.4
Mavelli, I.5
-
22
-
-
0030881686
-
Oxidative damage during aging targets mitochondrial aconitase
-
Yan LJ, Levine RL and Sohal RS. Oxidative damage during aging targets mitochondrial aconitase. Proc Natl Acad Sci USA 1997; 94: 11168-11172.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11168-11172
-
-
Yan, L.J.1
Levine, R.L.2
Sohal, R.S.3
-
23
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
Mecocci P, MacGarvey U, Kaufman AE, Koontz D, Shoffner JM, Wallace DC, et al. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann Neurol 1993; 34: 609-616.
-
(1993)
Ann Neurol
, vol.34
, pp. 609-616
-
-
Mecocci, P.1
Macgarvey, U.2
Kaufman, A.E.3
Koontz, D.4
Shoffner, J.M.5
Wallace, D.C.6
-
24
-
-
0031032817
-
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
-
Yakes FM and Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94: 514-519.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 514-519
-
-
Yakes, F.M.1
van Houten, B.2
-
25
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja G and Herrero A. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 2000; 14: 312-318.
-
(2000)
FASEB J
, vol.14
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
-
26
-
-
34948881208
-
Mitochondria: A hub of redox activities and cellular distress Control
-
Kakkar P and Singh BK. Mitochondria: a hub of redox activities and cellular distress Control. Mol Cell Biochem 2007; 305: 235-253.
-
(2007)
Mol Cell Biochem
, vol.305
, pp. 235-253
-
-
Kakkar, P.1
Singh, B.K.2
-
27
-
-
0034988397
-
Oxidative damage to mitochondria and aging
-
Van Remmen H and Richardson A. Oxidative damage to mitochondria and aging. Exp Gerontol 2001; 36: 957-968.
-
(2001)
Exp Gerontol
, vol.36
, pp. 957-968
-
-
van Remmen, H.1
Richardson, A.2
-
30
-
-
0028235259
-
Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria
-
Hsieh RH, Hou JH, Hsu HS and Wei YH. Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria. Biochem Mol Biol Int 1994; 32: 1009-1022.
-
(1994)
Biochem Mol Biol Int
, vol.32
, pp. 1009-1022
-
-
Hsieh, R.H.1
Hou, J.H.2
Hsu, H.S.3
Wei, Y.H.4
-
31
-
-
25144476923
-
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
-
Brand MD and Esteves TC. Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2005; 2: 85-93.
-
(2005)
Cell Metab
, vol.2
, pp. 85-93
-
-
Brand, M.D.1
Esteves, T.C.2
-
32
-
-
23944494249
-
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly
-
Fridell YW, Sánchez-Blanco A, Silvia BA and Helfand SL. Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly. Cell Metab 2005; 1: 145-152.
-
(2005)
Cell Metab
, vol.1
, pp. 145-152
-
-
Fridell, Y.W.1
Sánchez-Blanco, A.2
Silvia, B.A.3
Helfand, S.L.4
-
33
-
-
33645243792
-
Involvement of Drosophila uncoupling protein 5 in metabolism and aging
-
Sánchez-Blanco A, Fridell YW and Helfand SL. Involvement of Drosophila uncoupling protein 5 in metabolism and aging. Genetics 2006; 172: 1699-1710.
-
(2006)
Genetics
, vol.172
, pp. 1699-1710
-
-
Sánchez-Blanco, A.1
Fridell, Y.W.2
Helfand, S.L.3
-
34
-
-
24344491154
-
Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans
-
Iser WB, Kim D, Bachman E and Wolkow C. Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans. Mech Ageing Dev 2005; 126: 1090-1096.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 1090-1096
-
-
Iser, W.B.1
Kim, D.2
Bachman, E.3
Wolkow, C.4
-
35
-
-
0031869858
-
Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes
-
Harper ME, Monemdjou S, Ramsey JJ and Weindruch R. Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes. Am J Physiol 1998; 275: 197-206.
-
(1998)
Am J Physiol
, vol.275
, pp. 197-206
-
-
Harper, M.E.1
Monemdjou, S.2
Ramsey, J.J.3
Weindruch, R.4
-
36
-
-
36448950118
-
Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease
-
Gates AC, Bernal-Mizrachi C, Chinault SL, Feng C, Schneider JG, Coleman T, et al. Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease. Cell Metab 2007; 6: 497-505.
-
(2007)
Cell Metab
, vol.6
, pp. 497-505
-
-
Gates, A.C.1
Bernal-Mizrachi, C.2
Chinault, S.L.3
Feng, C.4
Schneider, J.G.5
Coleman, T.6
-
37
-
-
57049176975
-
The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice
-
Nabben M, Hoeks J, Briedé JJ, Glatz JF, Moonen-Kornips E, Hesselink MK, et al. The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. FEBS Lett 2008; 582: 4147-4152.
-
(2008)
FEBS Lett
, vol.582
, pp. 4147-4152
-
-
Nabben, M.1
Hoeks, J.2
Briedé, J.J.3
Glatz, J.F.4
Moonen-Kornips, E.5
Hesselink, M.K.6
-
38
-
-
52949106861
-
Membrane phospholipids, lipoxidative damage and molecular integrity: A causal role in aging and longevity
-
Pamplona R. Membrane phospholipids, lipoxidative damage and molecular integrity: a causal role in aging and longevity. Biochim Biophys Acta 2008; 1777: 1249-1262.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 1249-1262
-
-
Pamplona, R.1
-
39
-
-
0030841350
-
Protein oxidation in aging, disease, and oxidative stress
-
Berlett BS and Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 1997; 272: 20313-20216.
-
(1997)
J Biol Chem
, vol.272
, pp. 20313-20216
-
-
Berlett, B.S.1
Stadtman, E.R.2
-
40
-
-
0034992999
-
Stress, DNA damage and ageing - an integrative approach
-
Von Zglinicki T, Bürkle A and Kirkwood TB. Stress, DNA damage and ageing - an integrative approach. Exp Gerontol 2001; 36: 1049-1062.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1049-1062
-
-
von Zglinicki, T.1
Bürkle, A.2
Kirkwood, T.B.3
-
41
-
-
77953750914
-
Reproduction and its Endocrine control
-
In: Allen D, Ed., Times mirror/Mosby college publishing. US, St Louis: Missouri
-
Shauf C, Moffett D and Moffett S. Reproduction and its Endocrine control. In: Allen D, Ed. Human physiology. Times mirror/Mosby college publishing. US, St Louis: Missouri 1990; pp. 646-661.
-
(1990)
Human Physiology
, pp. 646-661
-
-
Shauf, C.1
Moffett, D.2
Moffett, S.3
-
42
-
-
77953791207
-
The male reproductive system
-
In: Foltin J, Lebowitz H and Boyle P, Eds., US: MacGraw Hill companies
-
Junqueira LC and Carneiro J. The male reproductive system. In: Foltin J, Lebowitz H and Boyle P, Eds. Basic histology. US: MacGraw Hill companies 2003; pp. 431-447.
-
(2003)
Basic Histology
, pp. 431-447
-
-
Junqueira, L.C.1
Carneiro, J.2
-
44
-
-
0011403166
-
Spermatogenesis, overview
-
In: Knobil E and Neill JD, Eds., San Diego: Academic Press
-
Hess RA. Spermatogenesis, overview. In: Knobil E and Neill JD, Eds. Enciclopedia of reproduction. San Diego: Academic Press 1999; pp. 539-545.
-
(1999)
Enciclopedia of Reproduction
, pp. 539-545
-
-
Hess, R.A.1
-
45
-
-
0000585726
-
The Cytology of the testis
-
In: Knobil E and Neill JD, Eds., New York: Raven Press Ltd
-
de Kreteser DM and Kerr JB. The Cytology of the testis. In: Knobil E and Neill JD, Eds. The physiology of reproduction. New York: Raven Press Ltd. 1994; pp. 1212-1241.
-
(1994)
The Physiology of Reproduction
, pp. 1212-1241
-
-
de Kreteser, D.M.1
Kerr, J.B.2
-
46
-
-
10844255002
-
Hormonal regulation of spermatogenesis
-
Holdcraft RW and Braun RE. Hormonal regulation of spermatogenesis. Int J Androl 2004; 27: 335-342.
-
(2004)
Int J Androl
, vol.27
, pp. 335-342
-
-
Holdcraft, R.W.1
Braun, R.E.2
-
47
-
-
0030061741
-
The endocrine regulation of spermatogenesis: Independent roles for testosterone and FSH
-
Maclachlan RI, Wreford NG, O'Donnell L, De Kretser DM and Robertson DM. The endocrine regulation of spermatogenesis: independent roles for testosterone and FSH. J Endocrinol 1996; 148: 1-9.
-
(1996)
J Endocrinol
, vol.148
, pp. 1-9
-
-
Maclachlan, R.I.1
Wreford, N.G.2
O'Donnell, L.3
de Kretser, D.M.4
Robertson, D.M.5
-
48
-
-
0031957180
-
Changes in carbohydrate metabolism of testicular germ cells during meiosis in the rat
-
Bajpai M, Gupta G and Setty BS. Changes in carbohydrate metabolism of testicular germ cells during meiosis in the rat. Eur J Endocrinol 1998; 138: 322-327.
-
(1998)
Eur J Endocrinol
, vol.138
, pp. 322-327
-
-
Bajpai, M.1
Gupta, G.2
Setty, B.S.3
-
49
-
-
4444342685
-
Lactate and energy metabolism in male germ cells
-
Boussouar F and Benahmed M. Lactate and energy metabolism in male germ cells. Trends Endocrinol Metab 2004; 15: 345-350.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 345-350
-
-
Boussouar, F.1
Benahmed, M.2
-
50
-
-
0037016403
-
Germ cell survival through carbohydrate-mediated interaction with Sertoli cells
-
Akama TO, Nakagawa H, Sugihara K, Narisawa S, Ohyama C, Nishimura S, et al. Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science 2002; 295: 124-127.
-
(2002)
Science
, vol.295
, pp. 124-127
-
-
Akama, T.O.1
Nakagawa, H.2
Sugihara, K.3
Narisawa, S.4
Ohyama, C.5
Nishimura, S.6
-
51
-
-
0032130527
-
The central role of Sertoli cells in spermatogenesis
-
Griswold MD. The central role of Sertoli cells in spermatogenesis. Semin Cell Dev Biol 1998; 9: 411-416.
-
(1998)
Semin Cell Dev Biol
, vol.9
, pp. 411-416
-
-
Griswold, M.D.1
-
52
-
-
9344243516
-
Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility
-
Miki K, Qu W, Goulding EH, Willis WD, Bunch DO, Strader LF, et al. Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc Natl Acad Sci USA 2004; 101: 16501-16506.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16501-16506
-
-
Miki, K.1
Qu, W.2
Goulding, E.H.3
Willis, W.D.4
Bunch, D.O.5
Strader, L.F.6
-
53
-
-
0019466605
-
Metabolism of glucose by Sertoli cells in culture
-
Robinson R and Fritz IB. Metabolism of glucose by Sertoli cells in culture. Biol Reprod 1981; 24: 1032-1041.
-
(1981)
Biol Reprod
, vol.24
, pp. 1032-1041
-
-
Robinson, R.1
Fritz, I.B.2
-
54
-
-
0021748633
-
The role of glucose, pyruvate and lactate in ATP production by rat spermatocytes and spermatids
-
Grootegoed JA, Jansen R and Van der Molen HJ. The role of glucose, pyruvate and lactate in ATP production by rat spermatocytes and spermatids. Biochim Biophys Acta 1984; 767: 248-256.
-
(1984)
Biochim Biophys Acta
, vol.767
, pp. 248-256
-
-
Grootegoed, J.A.1
Jansen, R.2
van der Molen, H.J.3
-
55
-
-
0021615259
-
Metabolism of pachytene primary spermatocytes from rat testes: Pyruvate maintenance of adenosine triphosphate level
-
Nakamura M, Okinaga S and Arai K. Metabolism of pachytene primary spermatocytes from rat testes: pyruvate maintenance of adenosine triphosphate level. Biol Reprod 1984; 30: 1187-1197.
-
(1984)
Biol Reprod
, vol.30
, pp. 1187-1197
-
-
Nakamura, M.1
Okinaga, S.2
Arai, K.3
-
56
-
-
0033088466
-
Expression of mitochondrial marker proteins during spermatogenesis
-
Meinhardt A, Wilhelm B and Seitz J. Expression of mitochondrial marker proteins during spermatogenesis. Hum Reprod Update 1999; 5: 108-119.
-
(1999)
Hum Reprod Update
, vol.5
, pp. 108-119
-
-
Meinhardt, A.1
Wilhelm, B.2
Seitz, J.3
-
57
-
-
33846026025
-
The role of mitochondrion in sperm function: Is there a role for oxidative phosphorilation or is this a purely glycolitic process?
-
Ruiz-Pesini E, Diéz-Sánchez C, López-Pérez MJ and Enríquez JA. The role of mitochondrion in sperm function: is there a role for oxidative phosphorilation or is this a purely glycolitic process? Curr Top Dev Biol 2007; 77: 3-19.
-
(2007)
Curr Top Dev Biol
, vol.77
, pp. 3-19
-
-
Ruiz-Pesini, E.1
Diéz-Sánchez, C.2
López-Pérez, M.J.3
Enríquez, J.A.4
-
58
-
-
0018773465
-
Morphological, histochemical and biochemical studies on germ cell mitochondria of normal rats
-
De Martino C, Floridi A, Marcante ML, Malorni W, Scorza Barcellona P, Bellocci M, et al. Morphological, histochemical and biochemical studies on germ cell mitochondria of normal rats. Cell Tissue Res 1979; 196: 1-22.
-
(1979)
Cell Tissue Res
, vol.196
, pp. 1-22
-
-
de Martino, C.1
Floridi, A.2
Marcante, M.L.3
Malorni, W.4
Scorza Barcellona, P.5
Bellocci, M.6
-
59
-
-
34250853373
-
Leydig cell steroidogenesis: Unmasking the functional importance of mitochondria
-
Haider SG. Leydig cell steroidogenesis: unmasking the functional importance of mitochondria. Endocrinology 2007; 148: 2581-2582.
-
(2007)
Endocrinology
, vol.148
, pp. 2581-2582
-
-
Haider, S.G.1
-
60
-
-
32244435076
-
Mitochondrial function in Leydig cell steroidogenesis
-
Hales DB, Allen JA, Shankara T, Janus P, Buck S, Diemer T, et al. Mitochondrial function in Leydig cell steroidogenesis. Ann NY Acad Sci 2005; 1061: 120-134.
-
(2005)
Ann NY Acad Sci
, vol.1061
, pp. 120-134
-
-
Hales, D.B.1
Allen, J.A.2
Shankara, T.3
Janus, P.4
Buck, S.5
Diemer, T.6
-
61
-
-
33746084479
-
Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis
-
Allen JA, Shankara T, Janus P, Buck S, Diemer T, Hales KH, et al. Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis. Endocrinology 2006; 147: 3924-3935.
-
(2006)
Endocrinology
, vol.147
, pp. 3924-3935
-
-
Allen, J.A.1
Shankara, T.2
Janus, P.3
Buck, S.4
Diemer, T.5
Hales, K.H.6
-
62
-
-
0037382663
-
Role of reactive oxygen species in the pathophysiology of human reproduction
-
Agarwal A, Saleh RA and Bedaiwy MA. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 2003; 79: 829-843.
-
(2003)
Fertil Steril
, vol.79
, pp. 829-843
-
-
Agarwal, A.1
Saleh, R.A.2
Bedaiwy, M.A.3
-
63
-
-
42449105332
-
Oxidative stress and male infertility-a clinical perspective
-
Tremellen K. Oxidative stress and male infertility-a clinical perspective. Hum Reprod Update 2008; 14: 243-258.
-
(2008)
Hum Reprod Update
, vol.14
, pp. 243-258
-
-
Tremellen, K.1
-
66
-
-
0036176556
-
Andropause: Clinical implications of the decline in serum testosterone levels with aging in men
-
Matsumoto AM. Andropause: clinical implications of the decline in serum testosterone levels with aging in men. J Gerontol A Biol Sci Med Sci 2002; 57: M76-99.
-
(2002)
J Gerontol a Biol Sci Med Sci
, vol.57
-
-
Matsumoto, A.M.1
-
67
-
-
0041834819
-
Declining testicular function in aging men
-
Tenover JS. Declining testicular function in aging men. Int J Impot Res 2003; 4: S3-8.
-
(2003)
Int J Impot Res
, vol.4
-
-
Tenover, J.S.1
-
69
-
-
0035097033
-
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
-
Harman SM, Metter EJ, Tobin JD, Pearson J and Blackman MR. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 2001; 86: 724-731.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 724-731
-
-
Harman, S.M.1
Metter, E.J.2
Tobin, J.D.3
Pearson, J.4
Blackman, M.R.5
-
70
-
-
0031001347
-
Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men
-
Morley JE, Kaiser FE, Perry HM III, Patrick P, Morley PM, Stauber PM, et al. Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men. Metabolism 1997; 46: 410-413.
-
(1997)
Metabolism
, vol.46
, pp. 410-413
-
-
Morley, J.E.1
Kaiser, F.E.2
Perry III, H.M.3
Patrick, P.4
Morley, P.M.5
Stauber, P.M.6
-
71
-
-
0025884064
-
Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts Male Aging Study
-
Gray A, Feldman HA and McKinlay JB. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J Clin Endocrinol Metab 1991; 73: 1016-1025.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 1016-1025
-
-
Gray, A.1
Feldman, H.A.2
McKinlay, J.B.3
-
72
-
-
20444390632
-
The decline in testosterone biosynthesis during male aging: A consequence of multiple alterations
-
Wang X and Stocco DM. The decline in testosterone biosynthesis during male aging: a consequence of multiple alterations. Mol Cell Endocrinol 2005; 238: 1-7.
-
(2005)
Mol Cell Endocrinol
, vol.238
, pp. 1-7
-
-
Wang, X.1
Stocco, D.M.2
-
74
-
-
14544277939
-
Andropause: Is androgen replacement therapy indicated for the aging male?
-
Hijazi RA and Cunningham GR. Andropause: is androgen replacement therapy indicated for the aging male? Annu Rev Med 2005; 56: 117-137.
-
(2005)
Annu Rev Med
, vol.56
, pp. 117-137
-
-
Hijazi, R.A.1
Cunningham, G.R.2
-
76
-
-
0023143155
-
Influence of age on pulsatile luteinizing hormone release and responsiveness of the gonadotrophs to sex hormone feedback in men
-
Deslypere JP, Kaufman JM, Vermeulen T, Vogelaers D, Vandalem JL and Vermeulen A. Influence of age on pulsatile luteinizing hormone release and responsiveness of the gonadotrophs to sex hormone feedback in men. J Clin Endocrinol Metab 1987; 64: 68-73.
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 68-73
-
-
Deslypere, J.P.1
Kaufman, J.M.2
Vermeulen, T.3
Vogelaers, D.4
Vandalem, J.L.5
Vermeulen, A.6
-
77
-
-
0024263835
-
Age-related alterations in the circadian rhythms of pulsatile luteinizing hormone and testosterone secretion in healthy men
-
Tenover JS, Matsumoto AM, Clifton DK and Bremner WJ. Age-related alterations in the circadian rhythms of pulsatile luteinizing hormone and testosterone secretion in healthy men. J Gerontol Med Sci 1988; 43: M163-M169.
-
(1988)
J Gerontol Med Sci
, vol.43
-
-
Tenover, J.S.1
Matsumoto, A.M.2
Clifton, D.K.3
Bremner, W.J.4
-
78
-
-
0032879225
-
Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig cell) defects in the healthy ageing male gonadotropic axis
-
Mulligan T, Iranmanesh A, Kerzner R, Demers LW and Veldhuis JD. Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig cell) defects in the healthy ageing male gonadotropic axis. Eur J Endocrinol 1999; 141: 257-266.
-
(1999)
Eur J Endocrinol
, vol.141
, pp. 257-266
-
-
Mulligan, T.1
Iranmanesh, A.2
Kerzner, R.3
Demers, L.W.4
Veldhuis, J.D.5
-
79
-
-
0034986061
-
Hormonal changes in aging men: A therapeutic indication?
-
Hermann M and Berger P. Hormonal changes in aging men: a therapeutic indication? Exp Gerontol 2001; 36: 1075-1082.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1075-1082
-
-
Hermann, M.1
Berger, P.2
-
80
-
-
51649122067
-
Aging and hormones of the hypothalamo-pituitary axis: Gonadotropic axis in men and somatotropic axes in men and women
-
Veldhuis JD. Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women. Ageing Res Rev 2008; 7: 189-208.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 189-208
-
-
Veldhuis, J.D.1
-
81
-
-
0023119507
-
Changes in amount and intracellular distribution of androgen receptor in human foreskin as a function of age
-
Roehrborn CG, Lange JL, George FW and Wilson JD. Changes in amount and intracellular distribution of androgen receptor in human foreskin as a function of age. J Clin Invest 1987; 79: 44-47.
-
(1987)
J Clin Invest
, vol.79
, pp. 44-47
-
-
Roehrborn, C.G.1
Lange, J.L.2
George, F.W.3
Wilson, J.D.4
-
82
-
-
0028824323
-
Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus
-
Tohgi H, Utsugisawa K, Yamagata M and Yoshimura M. Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus. Brain Res 1995; 700: 245-253.
-
(1995)
Brain Res
, vol.700
, pp. 245-253
-
-
Tohgi, H.1
Utsugisawa, K.2
Yamagata, M.3
Yoshimura, M.4
-
83
-
-
0023909352
-
Age-related changes in glucocorticoid and androgen receptors of cultured human pubic skin fibroblasts
-
Ono K, Haji M, Nawata H, Maki T, Kato K and Ibayashi H. Age-related changes in glucocorticoid and androgen receptors of cultured human pubic skin fibroblasts. Gerontology 1988; 34: 128-133.
-
(1988)
Gerontology
, vol.34
, pp. 128-133
-
-
Ono, K.1
Haji, M.2
Nawata, H.3
Maki, T.4
Kato, K.5
Ibayashi, H.6
-
84
-
-
0029862990
-
The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest old: Results from an Italian study of healthy free-living over-ninety-year-olds
-
Ravaglia G, Forti P, Maioli F, Boschi F, Bernardi M, Pratelli L, et al. The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest old: results from an Italian study of healthy free-living over-ninety-year-olds. J Clin Endocrinol Metab 1996; 81: 1173-1178.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1173-1178
-
-
Ravaglia, G.1
Forti, P.2
Maioli, F.3
Boschi, F.4
Bernardi, M.5
Pratelli, L.6
-
85
-
-
0029549896
-
Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline
-
Hornsby PJ. Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline. Ann NY Acad Sci 1995; 774: 29-46.
-
(1995)
Ann NY Acad Sci
, vol.774
, pp. 29-46
-
-
Hornsby, P.J.1
-
86
-
-
0018950079
-
Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin
-
Harman SM and Tsitouras PD. Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin. J Clin Endocrinol Metab 1980; 51: 35-40.
-
(1980)
J Clin Endocrinol Metab
, vol.51
, pp. 35-40
-
-
Harman, S.M.1
Tsitouras, P.D.2
-
87
-
-
27944460951
-
Mechanisms of hypoandrogenemia in healthy aging men
-
Liu PY, Iranmanesh A, Nehra AX, Keenan DM and Veldhuis JD. Mechanisms of hypoandrogenemia in healthy aging men. Endocrinol Metab Clin North Am 2005; 34: 935-955.
-
(2005)
Endocrinol Metab Clin North Am
, vol.34
, pp. 935-955
-
-
Liu, P.Y.1
Iranmanesh, A.2
Nehra, A.X.3
Keenan, D.M.4
Veldhuis, J.D.5
-
88
-
-
0031703817
-
Age-associated testosterone decline in men: Clinical issues for psychiatry
-
Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. Am J Psychiatry 1998; 155: 1310-1318.
-
(1998)
Am J Psychiatry
, vol.155
, pp. 1310-1318
-
-
Sternbach, H.1
-
89
-
-
33947261701
-
Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat
-
Weir CP and Robaire B. Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat. J Androl 2007; 28: 229-240.
-
(2007)
J Androl
, vol.28
, pp. 229-240
-
-
Weir, C.P.1
Robaire, B.2
-
90
-
-
0027254752
-
The effect of aging on the seminiferous epithelium of the brown Norway rat
-
Wright WW, Fiore C and Zirkin BR. The effect of aging on the seminiferous epithelium of the brown Norway rat. J Androl 1993; 14: 110-117.
-
(1993)
J Androl
, vol.14
, pp. 110-117
-
-
Wright, W.W.1
Fiore, C.2
Zirkin, B.R.3
-
91
-
-
0035159298
-
Selective loss of Sertoli cell and germ cell function leads to a disruption in sertoli cell-germ cell communication during aging in the Brown Norway rat
-
Syed V and Hecht NB. Selective loss of Sertoli cell and germ cell function leads to a disruption in sertoli cell-germ cell communication during aging in the Brown Norway rat. Biol Reprod 2001; 64: 107-112.
-
(2001)
Biol Reprod
, vol.64
, pp. 107-112
-
-
Syed, V.1
Hecht, N.B.2
-
92
-
-
65949119116
-
Female Mice Delay Reproductive Aging in Males
-
Schmidt JA, Oatley JM and Brinster RL. Female Mice Delay Reproductive Aging in Males. Biol Reprod 2009; 80(5): 1009-14.
-
(2009)
Biol Reprod
, vol.80
, Issue.5
, pp. 1009-1014
-
-
Schmidt, J.A.1
Oatley, J.M.2
Brinster, R.L.3
-
93
-
-
21244460324
-
Respiratory chain complexes and membrane fatty acids composition in rat testis mitochondria throughout development and ageing
-
Vázquez-Memije ME, Cárdenas-Méndez MJ, Tolosa A and Hafidi ME. Respiratory chain complexes and membrane fatty acids composition in rat testis mitochondria throughout development and ageing. Exp Gerontol 2005; 40: 482-490.
-
(2005)
Exp Gerontol
, vol.40
, pp. 482-490
-
-
Vázquez-Memije, M.E.1
Cárdenas-Méndez, M.J.2
Tolosa, A.3
Hafidi, M.E.4
-
94
-
-
36949015374
-
Analysis of age-associated changes in mitochondrial free radical generation by rat testis
-
Vázquez-Memije ME, Capin R, Tolosa A and El-Hafidi M. Analysis of age-associated changes in mitochondrial free radical generation by rat testis. Mol Cell Biochem 2008; 307: 23-30.
-
(2008)
Mol Cell Biochem
, vol.307
, pp. 23-30
-
-
Vázquez-Memije, M.E.1
Capin, R.2
Tolosa, A.3
El-Hafidi, M.4
-
95
-
-
57549112953
-
Rat testicular mitochondrial antioxidant defence system and its modulation by aging
-
Sahoo DK, Roy A and Chainy GB. Rat testicular mitochondrial antioxidant defence system and its modulation by aging. Acta Biol Hung 2008; 59: 413-424.
-
(2008)
Acta Biol Hung
, vol.59
, pp. 413-424
-
-
Sahoo, D.K.1
Roy, A.2
Chainy, G.B.3
-
96
-
-
0041326831
-
Effects of age and caloric restriction on glutathione redox state in mice
-
Rebrin I, Kamzalov S and Sohal RS. Effects of age and caloric restriction on glutathione redox state in mice. Free Radic Biol Med 2003; 35: 626-635.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 626-635
-
-
Rebrin, I.1
Kamzalov, S.2
Sohal, R.S.3
-
97
-
-
57649108974
-
Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak
-
Amaral S, Mota P, Rodrigues AS, Martins L, Oliveira PJ and Ramalho-Santos J. Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak. FEBS Lett 2008; 582: 4191-4196.
-
(2008)
FEBS Lett
, vol.582
, pp. 4191-4196
-
-
Amaral, S.1
Mota, P.2
Rodrigues, A.S.3
Martins, L.4
Oliveira, P.J.5
Ramalho-Santos, J.6
-
98
-
-
62549148154
-
Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)-A model for endangered species
-
Mota PC, Amaral S, Martins L, Pereira ML, Oliveira PJ and Ramalho-Santos J. Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)-A model for endangered species. Reprod Toxicol 2009; 27(2): 111-6.
-
(2009)
Reprod Toxicol
, vol.27
, Issue.2
, pp. 111-116
-
-
Mota, P.C.1
Amaral, S.2
Martins, L.3
Pereira, M.L.4
Oliveira, P.J.5
Ramalho-Santos, J.6
-
100
-
-
0035189247
-
Leydig cell aging: Steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme
-
Luo L, Chen H and Zirkin BR. Leydig cell aging: steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme. J Androl 2001; 22: 149-156.
-
(2001)
J Androl
, vol.22
, pp. 149-156
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
101
-
-
0029827114
-
Are leydig cell steroidogenic enzymes differentially regulated with aging?
-
Luo L, Chen H and Zirkin BR. Are leydig cell steroidogenic enzymes differentially regulated with aging? J Androl 1996; 17: 509-515
-
(1996)
J Androl
, vol.17
, pp. 509-515
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
102
-
-
0033592972
-
Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging
-
Chen H and Zirkin BR. Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging. Proc Natl Acad Sci USA 1999; 96: 14877-14881.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14877-14881
-
-
Chen, H.1
Zirkin, B.R.2
-
103
-
-
0030024408
-
Induction of Lipid Peroxidation during steroidogenesis in the Rat Testis
-
Peltola V, Huhtaniemi I, Metsa-Ketela T and Ahotupa M. Induction of Lipid Peroxidation during steroidogenesis in the Rat Testis. Endocrinology 1996; 137: 105-112.
-
(1996)
Endocrinology
, vol.137
, pp. 105-112
-
-
Peltola, V.1
Huhtaniemi, I.2
Metsa-Ketela, T.3
Ahotupa, M.4
-
104
-
-
0034899370
-
Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: Relationship to reduced steroidogenic function?
-
Chen H, Cangello D, Benson S, Folmer J, Zhu H, Trush MA, et al. Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: relationship to reduced steroidogenic function? Exp Gerontol 2001; 36: 13661-13673.
-
(2001)
Exp Gerontol
, vol.36
, pp. 13661-13673
-
-
Chen, H.1
Cangello, D.2
Benson, S.3
Folmer, J.4
Zhu, H.5
Trush, M.A.6
-
105
-
-
33644534186
-
Aging and the Brown Norway rat leydig cell antioxidant defense system
-
Luo L, Chen H, Trush MA, Show MD, Anway MD and Zirkin BR. Aging and the Brown Norway rat leydig cell antioxidant defense system. J Androl 2006; 27: 240-247.
-
(2006)
J Androl
, vol.27
, pp. 240-247
-
-
Luo, L.1
Chen, H.2
Trush, M.A.3
Show, M.D.4
Anway, M.D.5
Zirkin, B.R.6
-
106
-
-
34447316414
-
Trends in oxidative aging theories
-
Muller FL, Lustgarden MS, Jang Y, Richardson A and van Remmen H. Trends in oxidative aging theories. Free Radic Biol Med 2007; 43: 477-503.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 477-503
-
-
Muller, F.L.1
Lustgarden, M.S.2
Jang, Y.3
Richardson, A.4
van Remmen, H.5
-
107
-
-
50949112045
-
The oxidative stress theory of aging: Embattled or invincible? Insights from non-traditional organisms
-
Buffenstein R, Edrey YH, Yang T and Mele J. The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional organisms. Age 2008; 30: 99-109.
-
(2008)
Age
, vol.30
, pp. 99-109
-
-
Buffenstein, R.1
Edrey, Y.H.2
Yang, T.3
Mele, J.4
-
108
-
-
1842440378
-
Is defective electron transport at the hub of aging?
-
Maklashina E and Ackrell BAC. Is defective electron transport at the hub of aging? Aging Cell 2004; 3: 21-27.
-
(2004)
Aging Cell
, vol.3
, pp. 21-27
-
-
Maklashina, E.1
Ackrell, B.A.C.2
-
109
-
-
69049087814
-
Mitochondrial functionality and reproduction: From gonads and gametes to embryos and embryonic stem cells
-
Ramalho-Santos J, Varum S, Amaral S, Mota PC, Sousa AP and Amaral A. Mitochondrial functionality and reproduction: from gonads and gametes to embryos and embryonic stem cells. Hum Reprod Update 2009; 15(5): 553-72.
-
(2009)
Hum Reprod Update
, vol.15
, Issue.5
, pp. 553-572
-
-
Ramalho-Santos, J.1
Varum, S.2
Amaral, S.3
Mota, P.C.4
Sousa, A.P.5
Amaral, A.6
|